金子 啓介
| 歯学部 歯学科 | 助教 |
研究者情報
プロモーション
プロフィール
Neuroscience, Neurodevelopmental disorder, Anesthesiology, Multiple whole-cell patch-clamp (simultaneously sextuple patching, recording of unitary synapse, basic analysis) Axon/Dendrite patch-clamp Acute micro specimen slicing method Single-cell RNA transcriptome Optogenetics (Stereotaxic virus injection, patch-clamp in vitro and/or vivo) Voltage imaging Single-cell morphology (intracellular staining with biocytin) Immunohistochemistry
学位
研究キーワード
経歴
研究活動情報
受賞
- Society for Neuroscience, SfN (Society for Neuroscience) – JNS (Japan Neuroscience Society) Exchange Travel Award
★, 国際学会・会議・シンポジウム等の賞
Keisuke Kaneko and Ethan M. Goldberg - American Epilepsy Society, Grass Foundation – AES (American Epilepsy Society) Young Investigator Award
★, 国際学会・会議・シンポジウム等の賞
Keisuke Kaneko and Ethan M. Goldberg - 佐藤奨学金
- ロバート・ケネディ奨学金
- モリタ・ハノー補綴学賞
論文
- ★Targeted therapy improves cellular dysfunction, ataxia, and seizure susceptibility in a model of a progressive myoclonus epilepsy
Huijie Feng; Jerome Clatot; Keisuke Kaneko; Marco Flores-Mendez; Eric R. Wengert; Carly Koutcher; Emily Hoddeson; Emily Lopez; Demetrius Lee; Leroy Arias; Qiansheng Liang; Xiaohong Zhang; Ala Somarowthu; Manuel Covarrubias; Martin J. Gunthorpe; Charles H. Large; Naiara Akizu; Ethan M. Goldberg
Cell Reports Medicine, 2024年01月, 査読有り - ★Developmentally regulated impairment of parvalbumin interneuron synaptic transmission in an experimental model of Dravet syndrome
Keisuke Kaneko; Christopher B. Currin; Kevin M. Goff; Eric R. Wengert; Ala Somarowthu; Tim P. Vogels; Ethan M. Goldberg
Cell Reports, 2022年03月, 査読有り, 通常論文
筆頭著者 - ★Corticohippocampal circuit dysfunction in a mouse model of Dravet syndrome
Joanna Mattis; Ala Somarowthu; Kevin M Goff; Evan Jiang; Jina Yom; Nathaniel Sotuyo; Laura M Mcgarry; Huijie Feng; Keisuke Kaneko; Ethan M Goldberg
eLife, 2022年02月, 査読有り - ★Propofol-induced potentiation of GABAA receptor-mediated tonic Cl-currents in the rat insular cortex
金子啓介
2019年03月, 査読有り, 通常論文
筆頭著者 - ★Propofol-induced spike firing suppression is more pronounced in pyramidal neurons than in fast-spiking neurons in the rat insular cortex.
Keisuke Kaneko
Neuroscience, 2016年10月, 査読有り, 通常論文
筆頭著者 - Desflurane-Induced Delayed Onset of Malignant Hyperthermia: A Case Report.
Seki H; Takei N; Kajiwara M; Tsumura M; Naito N; Tsujiuchi M; Higa M; Koyanagi Y; Oka S; Kaneko K
Anesthesia Progress, 2026年06月, 査読有り
ラスト(シニア)オーサー - A new phenotype identification method with the fluorescent expression in cross-sectioned tails in Thy1-GCaMP6s transgenic mice
Shutaro Kobayashi; Kazunori O’Hashi; Keisuke Kaneko; Satomi Kobayashi; Shouhei Ogisawa; Morio Tonogi; Satoshi Fujita; Masayuki Kobayashi
Journal of Oral Science, 2022年02月, 査読有り - Presynaptic NK1 Receptor Activation by Substance P Suppresses EPSCs via Nitric Oxide Synthesis in the Rat Insular Cortex.
Keisuke Kaneko
Neuroscience, 2020年12月, 査読有り, 通常論文 - Orexin facilitates GABAergic IPSCs via postsynaptic OX1 receptors coupling to the intracellular PKC signalling cascade in the rat cerebral cortex.
Keisuke Kaneko
Neuropharmacology, 2019年02月, 査読有り, 通常論文 - Menthol-induced facilitation of cerebrocortical excitatory propagation induced by air puff stimulation of the nasal cavity in the rat: An optical imaging study.
Keisuke Kaneko
Neuroscience letters, 2018年12月, 査読有り, 通常論文
MISC
講演・口頭発表等
- ★Neocortical parvalbumin-positive fast-spiking GABAergic interneurons exhibit persistent deficits in axonal function in an experimental mouse model of Dravet syndrome
Keisuke Kaneko and Ethan M. Goldberg
Better Patient Outcomes through Diversity Poster session in American Epilepsy Society 2020 Annual Meeting, 2020年12月, American Epilepsy Society, 招待有り - ★Neocortical parvalbumin-positive fast-spiking GABAergic interneurons exhibit persistent deficits in axonal function in an experimental mouse model of Dravet syndrome
Keisuke Kaneko and Ethan M. Goldberg
American Epilepsy Society 2020 Annual Meeting, 2020年12月, American Epilepsy Society, 通常論文 - Neocortical parvalbumin-positive interneurons exhibit persistent deficits in axonal function in an experimental mouse model of Dravet syndrome (Scn1a+/- mice)
Keisuke Kaneko and Ethan M. Goldberg
36th Annual MINS UnRetreat Symposium, 2020年04月, Mahoney Institute for Neurosciences, 通常論文 - Neocortical parvalbumin-positive interneurons exhibit persistent deficits in axonal function in an experimental mouse model of Dravet syndrome
Keisuke Kaneko and Ethan M. Goldberg
Japan Neuroscience Society 2020, 2020年, 通常論文 - ラット大脳皮質に存在するコリン作動性介在ニューロンは錐体細胞を脱抑制させる
金子啓介,松村幸恵,藤田智史,小林真之
三叉神経領域の感覚-運動統合機構研究会, 2018年12月, 通常論文 - Cholinergic inputs to cortical cholinergic neurons facilitate disinhibition of excitatory neurons in the rat cerebral cortex
Keisuke Kaneko; Sachie Matsumura; Yoshiyuki Oi; Masayuki Kobayashi
Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology), 2018年, 通常論文 - Cholinergic inputs to cortical cholinergic neurons facilitate disinhibition of excitatory neurons in the rat cerebral cortex
Kaneko K; Matsumura S; Oi Y; and Kobayashi M
Society for Neuroscience 2018, 2018年, 通常論文 - Effects of propofol on the electrophysiological membrane properties of pyramidal ,neurons and GABAergic interneurons in the rat agranular insular cortex
3.Keisuke Kaneko; Yuko Koyanagi; Masayuki Kobayashi; Yoshiyuki Oi
日本麻酔科学会第64回学術集会, 2017年06月, 通常論文 - ラット大脳皮質に存在するコリン作動性ニューロンの役割
金子啓介; 小林真之; 大井良之
第69回日本大学歯学会総会・学術大会, 2017年05月, 日本大学歯学部, 通常論文 - Propofol-mediated spike firing suppression is more sensitive in pyramidal neurons,than in fast-spiking interneurons in the rat insular cortex
2.Keisuke Kaneko; Yuko Koyanagi; Yoshiyuki Oi; Masayuki Kobayashi
Society for Neuroscience, 2016年11月, 通常論文 - Neuronal subtype-dependent modulation of electrophysiological properties by propofol,in rat cerebral cortex
1.Keisuke Kaneko; Yuko Koyanagi; Yoshiyuki Oi; Masayuki Kobayashi
第89回日本薬理学会年会, 2016年03月, 通常論文
