HIDAI Chiaki
| School of Medicine Department of Medicine | Professor |
Researcher Information
Research activity information
Paper
- Accreditation of Medical Education at Nihon University School of Medicine
Chiaki Hidai; Saki Suzuki; Yuriko Abe
Journal of Nihon University Medical Association, Dec. 2023 - Our Journey to the Unification of Learning Management Systems (LMS) in Disarray
Saki Suzuki; Yuriko Abe; Eric H. Jego; Chiaki Hidai
Medical Education (Japan), Dec. 2023, Refereed - 医学生の授業評価に対する認識と行動に関する探索的研究
鈴木 沙季; 今福 輪太郎; 川上 ちひろ; 阿部 百合子; Jego Eric H.; 西城 卓也; 日台 智明
医学教育, Jul. 2023 - 医学生の授業評価に対する認識と行動に関する探索的研究
鈴木 沙季; 今福 輪太郎; 川上 ちひろ; 阿部 百合子; Jego Eric H.; 西城 卓也; 日台 智明
医学教育, Jul. 2023 - ChatGPTを活用したアクティブラーニング強化に関するアイデアの授業内実践(Lesson Ideas for using ChatGPT and AI to enhance active learning in medical school classrooms)
Jego Eric H.; 鈴木 沙季; 阿部 百合子; 内海 邑; 日台 智明
医学教育, Jul. 2023 - ChatGPTを活用したアクティブラーニング強化に関するアイデアの授業内実践(Lesson Ideas for using ChatGPT and AI to enhance active learning in medical school classrooms)
Jego Eric H.; 鈴木 沙季; 阿部 百合子; 内海 邑; 日台 智明
医学教育, Jul. 2023 - マルチメディア模擬患者の映像医療面接を用いたオンライン参加型PBLの試み
阿部 百合子; 大谷 尚子; 井上 広一; 吉川 裕子; 林田 亜紋; 高津 洋志; Jego Eric H.; 鈴木 沙季; 日台 智明
医学教育, Jul. 2023 - 医学英語ライティング教育 10：医学英語の授業におけるパラグラフ・ライティング教育の試み 3パラグラフを書いてみよう
Ryoko Takahashi; 沙季 鈴木; 直紀 野田; ハジメ ジェーゴ エリック; 淳 飯島; 智明 日臺
Journal of Nihon University Medical Association, Feb. 2022 - EGF domain peptide of Developmentally regulated endothelial locus1 facilitates gene expression of extracellularly applied plasmid DNA
Hisataka Kitano; Kazunori Kanemaru; Toshio Miki; Chiaki Hidai
Biologicals, Jan. 2022, Refereed, Not invited
Last - Activation peptide of coagulation factor IX improves the prognosis after traumatic brain injury
Yuusuke Fujiwara; Hisataka Kitano; Takamitsu Yamamoto; Shinichiro Kokubun; Chiaki Hidai
Biochemical and Biophysical Research Communications, Sep. 2021 - Oral multicentric carcinoma arising from four different sites in a female patient
Hisataka Kitano; Yoh Masaoka; Atsushi Mamiya; Yusuke Fujiwara; Toshio Miki; Chiaki Hidai.
J Oral Sci, Mar. 2021, Refereed, Not invited
Last - Combination Cancer Therapy of a Del1 Fragment and Cisplatin Enhanced Therapeutic Efficiency In Vivo.
Hisataka Kitano; Yoh Masaoka; Atsushi Mamiya; Yusuke Fujiwara; Toshio Miki; Chiaki Hidai.
In Vivo, Mar. 2021, Refereed, Not invited
Last - An Epidermal Growth Factor Motif of Developmental Endothelial Locus 1 Protein Inhibits Efficient Angiogenesis in Explanted Squamous Cell Carcinoma In Vivo
Hisataka Kitano; Atsushi Mamiya; Tomomi Ishikawa; Yusuke Fujiwara; Yoh Masaoka; Toshio Miki; Chiaki Hidai
Rev Invest Clin, May 2020, Refereed, Not invited
Last - 医学英語ライティング教育1
Ryoko Takahashi; Atsushi Ijima; Naoki Noda; Kazuhide Takada; Chiaki Hidai
J. Nihon Univ. Med. Ass., 2019, Refereed, Invited - 医学英語ライティング教育2
Ryoko Takahashi; Atsushi Ijima; Naoki Noda; Kazuhide Takada; Chiaki Hidai
J. Nihon Univ. Med. Ass., 2019, Refereed, Invited - EGF-like domains with a C-x-D-x(4)-Y-x-C motif
Chiaki Hidai
Open Access Journal of Translational Medicine & Research, Apr. 2018, Refereed, Invited
Lead - Treatment of Endothelial Permeability with Hemostatic Factors
Chiaki Hidai
Journal of Blood Disorders, Symptoms & Treatments, Apr. 2018, Refereed, Invited
Lead - Bidirectional Pathologic Effects of Thrombin
Chiaki Hidai
Anatomy & Physiology, Feb. 2018, Refereed, Invited
Lead - Efficient Cancer Gene therapy with a Del1 fragment administered by hypodermic injection in a mouse explanted tumor model.
H. Kitano; T. Ishikawa; R. Tamura; S. Kokubun; and C. Hidai
Translational Cancer Research, 2018, Refereed, Invited
Corresponding - XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells
Akihiro Kishino; Ken Hayashi; Chiaki Hidai; Takeshi Masuda; Yasuyuki Nomura; Takeshi Oshima
SCIENTIFIC REPORTS, Jun. 2017, Refereed, Not invited - EGF domain of coagulation factor IX is conducive to exposure of phosphatidylserine
Chiaki Hidai; Yusuke Fujiwara; Shinichiro Kokubun; Hisataka Kitano
CELL BIOLOGY INTERNATIONAL, Apr. 2017, Refereed, Not invited - Activation peptide of coagulation factor IX regulates endothelial permeability
Atsushi Mamiya; Hisataka Kitano; Shinichiro Kokubun; Chiaki Hidai
TRANSLATIONAL RESEARCH, Nov. 2016, Not refereed, Not invited - The first EGF domain of coagulation factor IX attenuates cell adhesion and induces apoptosis
Ishikawa T; Kitano H; Mamiya A; Kokubun S; Hidai C
Biosci Rep., Apr. 2016, Refereed, Not invited
Corresponding - Long-term gene therapy with Del1 fragment using nonviral vectors in mice with explanted tumors
Hisataka Kitano; Atsushi Mamiya; Tomomi Ishikawa; Kayo Egoshi; Shinichiro Kokubun; Chiaki Hidai
ONCOTARGETS AND THERAPY, 2016, Refereed, Not invited - Coagulation factor IX regulates cell migration and adhesion in vitro.
H Kitano; A Mamiya; T Ishikawa; S Kokubun; C Hidai
Cell Biology International, Oct. 2015, Refereed, Not invited
Corresponding - 【よくわかる遺伝子】 機能と遺伝子 味覚と遺伝子 hTAS2R遺伝子発現を用いたヒト舌における味覚機能の新しい指標
高尾 恭一; 小池 文彦; 高尾 哲也; 日臺 智明; 國分 眞一朗; 小池 一喜; 須賀 比奈子
JOHNS, Jun. 2014, Not refereed, Not invited - An epidermal growth factor motif from Del1 protein increases the efficiency of in vivo gene transfer with a non-viral vector.
Mamiya A; Kitano H; Takao K; Kokubun S; Komiya M; Hidai C.
Mol Biotechnol., Jan. 2013, Refereed, Not invited
Corresponding - Efficient nonviral gene therapy with FasL and Del1 fragments in mice
Hisataka Kitano; Atsushi Mamiya; Shinichiro Kokubun; Chiaki Hidai
JOURNAL OF GENE MEDICINE, Nov. 2012, Not refereed, Not invited - The extracellular matrix protein Del1 induces apoptosis via its epidermal growth factor motif.
Hisataka Kitano; Shinnichiro Kokubun
Biochem Biophys Res Commun., Mar. 2010, Refereed, Not invited
Corresponding - The Del1 deposition domain can immobilize 3 alpha-hydroxysteroid dehydrogenase in the extracellular matrix without interfering with enzymatic activity
Chiaki Hidai; Hisataka Kitano; Shinichiro Kokubun
BIOPROCESS AND BIOSYSTEMS ENGINEERING, Aug. 2009, Refereed, Not invited - An epidermal growth factor-like repeat of Del1 protein increases the efficiency of gene transfer in vitro
kitano h.; kawana m.; kokubun s.
Molecular biotechnology, Jun. 2008, Refereed, Not invited
Corresponding - Discoidin domain of Del1 protein contributes to its deposition in the extracellular matrix.
Kawana M; Kitano H; Kokubun S
Cell & Tissue Research, Oct. 2007, Refereed, Not invited
Lead - Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery
Chiaki Hidai1; 6; Masatoshi Kawana2; Kiyoshi Habu3; Hiromi Kazama1; Yosuke Kawase3; Takamitsu Iwata3; Hiroshi Suzuki4; Thomas Quertermous5; and Shinichiro Kokubun1
Anatomical Research, 2005, Refereed, Not invited
Lead - Heparin regulates transcription of endotheline-1 gene in endothelial cells.
Kazue Kuwahara-Watanabe; Chiaki Hidai; Hiromi Ikeda Yoshikazu Aoka; Ken-ichiro Ichikawa Nobuo Iguchi; Masako Okada-Ohno; Jinko Yokota; Hiroshi Kasanuki; Masatoshi Kawana
Journal of Vascular Research, 2005, Refereed, Not invited - Endothelin-1 gene expression in endothelial cells is potently inhibited by a vasodilator, dilazep.
Shrestha B; Hidai C; Ikeda H; Okada-Ohno M; Kasanuki H; Kawana M.
hypertension research, 2004, Refereed, Not invited - ラット心虚血再灌流モデルの非虚血領域心筋においてアデノシンA1受容体遺伝子の発現は増加する
OHYA Toshiyuki; HIDAI Chiaki; NAKAYAMA Tomohiro; KAZAMA Hiromi; KANMATSUSE Katsuo; KOKUBUN Shinichiro
脈管学, 2004, Refereed, Not invited
Corresponding - Specific Regulation of Nucleocytoplasmic Distribution of Poly(C) -Binding Protein Gene mRNA in Mouse Development.
Chiaki Hidai1*; Masako Ohno2*; Hiromi Kazama1; Hiromi Ikeda2; Hiroshi Kasanuki2; Shinichiro Kokubun1; and Masatoshi Kawana2#
BBRC, 2003, Refereed, Not invited
Lead - FGF-1 Enhanced Cardiogenesis in Differentiating Embryonal Carcinoma Cell Cultures, Which was Opposite to the Effect of FGF-2.
Hidai Chiaki; Masako Okada; Hiromi Ikeda; Hirotaka Nagashima; Rumiko Matsuoka; Thomas Quertermous; Hiroshi Kasanuki; Shinichiro Kokubun; and Masatoshi Kawana
Journal of Molecular Cellular Cardiology, 2003, Not refereed, Not invited
Lead - 細胞外基質タンパクDel1による血管内皮細胞間の接着の制御
風間 宏美; 日臺 智明; 有賀 豊彦; 國分 眞一朗
日大医学雑誌, 2003, Not refereed, Not invited - The embryonic angiogenic factor del1 accelerates tumor growth by enhancing vascular formation
Aoka Y; Johnson FL; Penta K; Hirata Ki K; Hidai C; Schatzman R; Varner JA; Quertermous T
microvascular research, 2002, Refereed, Not invited - ラット舌より分離されたGPR14受容体の呈味性物質に対する応答性
高尾哲也、酒井麻美子、吉田友佳、高尾恭一、日台智明、風間宏美、須賀比奈子
精糖技術研究会誌, 2002, Refereed, Not invited - 心房房室結節解離を伴った房室結節リエントリー頻拍の一例
笠貫宏、大西哲、稲葉茂樹、細田瑳一
臨床心臓電気生理, 2002, Not refereed, Not invited
Lead - Retinoic acid suppresses endothelin-1 gene expression at the transcription level in endothelial cells
Yokota J; Kawana M; Hidai C; Aoka Y; Ichikawa K; Iguchi N; Okada M; Kasanuki H
Atherosclerosis, 2001, Refereed, Not invited - Del-1 induces integrin signaling and angiogenesis by ligation of αVβ3.
K Penta; JA Varner; L Liaw; C Hidai; R Schatzman; T Quertermous
J. Biol. Chem., 1999, Not refereed, Not invited - Cloning and characterization of developmental endothelial locus-1.
C Hidai; T Zupancic; K Penta; A Mikhail; M Kawana; EE Quertermous; Y Aoka; M Fukagawa; Y Matsui; D Platika; R Auerbach; BLM Hogan; R Snodgrass; T Quertermous
Genes and Development, 1998, Not refereed, Not invited - The role of cadherin-catenin-cytoskeleton complex in angiogenesis: antisense oligonucleotide of plakoglobin promotes angiogenesis in vitro, and protein kinase C (PKC) enhances angiogenesis through the plakoglobin signaling pathway
Nagashima; H. Okada; M. Hidai; C. Hosoda; S. Kasanuki; H. Kawana; M.
Heart Vessels, 1997, Not refereed, Not invited - Endogeneous endothelin-1 mediates cardiac hypertrophy and Switching of myosin heavy chain gene expression in rat Ventricular myocardium
K Ichikawa; C Hidai; C Okuda; S Kimata; R Matsuoka; S Hosoda; T Quertermous; M Kawana
J. Am. Col. Cardiol., 1996, Not refereed, Not invited - 胎生初期に血管内皮細胞に限局して発現する遺伝子del-1の同定と解析
東京女子医科大学雑誌, 1996, Refereed, Not invited
Lead - Determining factors of successful percutaneous transvenous mitral commissurotomy and eligible indications for the procedure
Kebukawa; K. Magosaki; N. Sakai; K. Umemura; J. Ueda; T. Kimura; H. Hidai; C. Suzuki; T. Kasanuki; H. Hosoda; S.
Kokyu To Junkan, 1993, Refereed, Not invited - 拡張型心筋症における短期予後因子としての右室機能
心筋症調査研究班報告集, 1993, Not refereed, Not invited
Lead
MISC
- オンライン授業が学生生活にもたらす身体的精神的影響
鈴木 沙季; 阿部 百合子; Eric Jego; 日台 智明
医学教育, Jul. 2022 - Constructive Alignment 日本の機能的な問診票評価(JFHTA)(Constructive Alignment: Japan Functional History Taking Assessment(JFHTA))
Jego Eric H.; 鈴木 沙季; 阿部 百合子; 日台 智明
医学教育, Jul. 2022 - マルチメディア模擬患者の開発とオンライン参加型PBLの試み
阿部 百合子; 鈴木 沙季; 丸岡 秀一郎; 伊藤 玲子; 日臺 智明
医学教育, Jul. 2022 - オンラインの少人数ディスカッションは学生の孤独を癒す効果があるか
阿部 百合子; ジェーゴ・エリック; 鈴木 沙季; 日臺 智明
医学教育, Jul. 2021 - 成績分布の経時的変化の検証
鈴木 沙季; 阿部 百合子; ジェーゴ・エリック; 日臺 智明
医学教育, Jul. 2021 - Accentuation of glycolysis of vascular endothelial cell under the hypoxia by activation peptide of coagulation factor IX
A. Mamiya; H. Kitano; Y. Fujiwara; T. Ishikawa; E. Yamamoto; C. Hidai
MOLECULAR BIOLOGY OF THE CELL, 2016, Not refereed, Not invited - Coagulation factor IX improves the prognosis of pulmonary edema under the hypoxia.
Y. Fujiwara; H. Kitano; A. Mamiya; C. Hidai; K. Shinichiro
MOLECULAR BIOLOGY OF THE CELL, 2016, Not refereed, Not invited - The apoptotic signal by an EGF motif of coagulation factor IX
T. Ishikawa; H. Kitano; A. Mamiya; Y. Fujiwara; K. Shinichiro; C. Hidai; Y. Eri
MOLECULAR BIOLOGY OF THE CELL, 2015, Not refereed, Not invited - Coagulation factor IX regulates cell migration and adhesion.
A. Mamiya; H. Kitano; T. Ishikawa; Y. Fujiwara; E. Yamamoto; M. Yoshida; C. Hidai; S. Kokubun
MOLECULAR BIOLOGY OF THE CELL, 2015, Not refereed, Not invited - An EGF motif of Del1 suppresses Notch function and hampers angiogenesis in vivo
H. Kitano; A. Mamiya; T. Ishikawa; Y. Fujiwara; E. Yamamoto; S. Kokubun; C. Hidai
MOLECULAR BIOLOGY OF THE CELL, 2015, Not refereed, Not invited - Coagulation factor IX regulates cell migration and adhesion in vitro
A. Mamiya; H. Kitano; T. Ishikawa; Y. Fujiwara; M. Yoshida; Kokubun; C. Hidai
MOLECULAR BIOLOGY OF THE CELL, Dec. 2014, Not refereed, Not invited - Clustering of lipid rafts is accelerated by active coagulation factor IX via exposure to phosphatidylserine at the adhesion complex.
H. Kitano; A. Mamiya; T. Ishikawa; Y. Fujiwara; M. Yoshida; S. Kokubun; C. Hidai
MOLECULAR BIOLOGY OF THE CELL, Dec. 2014, Not refereed, Not invited - Membrane endocytosis plays a significant role in de-adhesion induced by activated coagulation factor IX
C. Hidai; H. Kitano; A. Mamiya; T. Ishikawa; S. Kokubun
MOLECULAR BIOLOGY OF THE CELL, 2013, Not refereed, Not invited - Membrane endocytosis plays a significant role in de-adhesion induced by activated coagulation factor IX
C. Hidai; H. Kitano; A. Mamiya; T. Ishikawa; S. Kokubun
MOLECULAR BIOLOGY OF THE CELL, 2013, Not refereed, Not invited - A discoidin domain of the Del1 protein is essential and sufficient for its deposition in the extracellular matrix.
C. Hidai; H. Kitano; A. Mamiya; S. Kokubun
MOLECULAR BIOLOGY OF THE CELL, 2011, Not refereed, Not invited - An EGF motif of Del1 induces apoptosis in vitro.
H. Kitano; A. Mamiya; M. Komiya; S. Kokubun; C. Hidai
MOLECULAR BIOLOGY OF THE CELL, 2011, Not refereed, Not invited - THE ENERGY METABOLISM IN AGGREGATING SLIME MOLD
Chiaki Hidai; Takanobu Sumii; Seiichiro Nakabayashi; Shinichiro Kokubun
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not refereed, Not invited - 健常者および味覚異常者に発現する味覚受容体とその変化
高尾哲也; 森明子; 高尾恭一; 小池文彦; 日台智明; 風間宏美; 清水初美; 吉田友佳; 須賀比奈子
日本味と匂学会誌, 01 Dec. 2005, Not refereed, Not invited - 細胞外基質蛋白Del-1による細胞間接着の制御
風間 宏美; 日臺 智明; 國分 眞一朗
日本農芸化学会, 2003, Not refereed, Not invited - ラット舌上に存在するGPR14受容体の呈味物質に対する応答性
高尾哲也; 酒井麻美子; 吉田友佳; 高尾恭一; 日台智明; 風間宏美; 須賀比奈子
日本食品科学工学会大会講演集, 29 Aug. 2002, Not refereed, Not invited - ENDOTHELIN MEDIATES CARDIAC-HYPERTROPHY AND SWITCHING OF MYOSIN HEAVY-CHAIN GENE-EXPRESSION IN RAT VENTRICULAR MYOCARDIUM
K ICHIKAWA; C HIDAI; M KAWANA; C OKUDA; T OKA; J YOKOTA; T TANINO; M HATSUMI; S KIMATA; R MATSUOKA; E HIRATSUKA; M NARUSE; S HOSODA
CIRCULATION, Oct. 1993, Not refereed, Not invited - ENDOTHELIN-1 GENE-EXPRESSION IS ENHANCED IN THE LUNG WITH MONOCROTALINE-INDUCED PULMONARY-HYPERTENSION
C OKUDA; M KAWANA; C HIDAI; T OKA; S IMAMURA; R MATSUOKA; M HORIE; S KIMATA; M NARUSE; S HOSODA
CIRCULATION, Oct. 1992, Not refereed, Not invited
Books and other publications
Lectures, oral presentations, etc.
- 学生の自主的な学びをささえる
日台智明
第54回 日本医学教育学会, Aug. 2022 - Fuluoresent microscopic analysis of single cell metabolism in Dictyostelium Discoideum
Takanobu Sumii; Seiichiro Nakabayashi; Shinichiro Kokubun
Cold Spring Harbor meeting on computational cell biology, Mar. 2009, Not invited - 細胞性粘菌の多細胞化に伴うエネルギー代謝量の変化
野村竜文
日本生物物理学会年会, Nov. 2006, Not invited
Research Themes
- Activation peptide of coagulation factor IX protects vascular endothelial cells
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2021 - 31 Mar. 2024
日だい 智明 - Research of the mechanism of exosome propagation for fibromyalgia accompanied with the cochlea and vestibular symptoms
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2018 - 31 Mar. 2022
NOMURA Yasuyuki - Development of a new keloid treatment using dedifferentiated fat cells and coagulation factor-derived protein.
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2017 - 31 Mar. 2021
NAKAZAWA Hiroaki - The function of activation peptide of coagulation factor IX
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2017 - 31 Mar. 2021
HIDAI Chiaki - The mechanism underlying the upregulation of A1R mRNA expression in non-ischemic raight ventricle by the ischemia of left ventricle
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2003 - 2004
KOKUBUN Shinichiro; HIDAI Chiaki - Function of Dell in Embryonic Development
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2001 - 2002
HIDAI Chiaki; KAWANA Masatoshi - 心筋移植療法のための心筋分化誘導に関する研究
日本学術振興会, 科学研究費助成事業, 1999 - 2000
日臺 智明 - 新しい細胞外基質蛋白del-1の心臓発生における機能の研究
日本学術振興会, 科学研究費助成事業, 1997 - 1998
日〓 智明; 日臺 智明; 川名 正敏 - 内皮細胞分化調節遺伝子の心臓発生、分化に対する役割
日本学術振興会, 科学研究費助成事業, 1994 - 1994
川名 正敏; 市川 健一郎; 日台 智明; 上田 みどり; 木全 心一
