Iwamoto Masaaki

College of Humanities and Sciences Department of BiosciencesProfessor

Research Keyword

  • 繊毛虫
  • テトラヒメナ
  • ゾウリムシ
  • 接合
  • 細胞核
  • 系列分化
  • 核膜孔複合体
  • ヌクレオポリン
  • 核ー細胞質間輸送
  • 収縮胞

Field Of Study

  • Life sciences, Cell biology
  • Life sciences, Molecular biology

Career

  • Apr. 2020 - Present
    Nihon University, College of Humanities and Sciences Department of Biosciences, 教授
  • 2012 - Mar. 2020
    情報通信研究機構, 主任研究員
  • 2007 - 2012
    情報通信研究機構, 専攻研究員
  • 2004 - 2007
    情報通信研究機構, 特別研究員
  • 2001 - 2004
    米国ハワイ大学パシフィックバイオメディカルリサーチセンター, 博士研究員

Educational Background

  • 1996 - 2001
    Osaka University
  • 1994 - 1996
    Yamaguchi University

Member History

  • Nov. 2021 - Present
  • Sep. 2020 - Present
  • Nov. 2009 - Nov. 2024
  • Nov. 2012 - Oct. 2018

Award

  • 第45回日本発生生物学会・第64回日本細胞生物学会合同大会, Young Presenters Award for Poster Presentation
    岩本 政明
  • 日本原生動物学会賞
    岩本 政明

Paper

  • Close cooperation between Semi1 and Semi2 proteins is essential for pronuclear positioning in Tetrahymena thermophila
    Akematsu T; Loidl J; Fukuda Y; Iwamoto M
    Molecular Biology of the Cell, Mar. 2025
  • Live CLEM imaging of Tetrahymena to analyze the dynamic behavior of the nuclear pore complex
    Haraguchi T, Osakada H, Iwamoto M
    Methods in Molecular Biology, Apr. 2022, Refereed, Invited
  • Asymmetrical localization of Nup107-160 subcomplex components within the nuclear pore complex in fission yeast
    Asakawa H; Kojidani T; Yang HJ; Ohtsuki C; Osakada H; Matsuda A; Iwamoto M; Chikashige Y; Nagao K; Obuse C; Hiraoka Y; Haraguchi T
    PLOS Genetics, Jun. 2019, Refereed, Not invited
  • Subcellular targeting of the Euplotes raikovi kinase Er-MAPK1, as revealed by expression in different cell systems
    Candelori A; Yamamoto TG; Iwamoto M; Montani M; Amici A; Vallesi A
    Frontiers in Cell and Developmental Biology, 2019, Refereed, Not invited
  • Identification of the evolutionarily conserved nuclear envelope proteins Lem2 and MicLem2 in Tetrahymena thermophila
    Iwamoto M; Fukuda Y; Osakada H; Mori C; Hiraoka Y; Haraguchi T
    Gene, Jan. 2019, Refereed, Not invited
    Lead
  • Remodeling the specificity of an endosomal CORVET tether underlies formation of regulated secretory vesicles in the ciliate Tetrahymena thermophila
    Sparvoli D; Richardson E; Osakada H; Lan X; Iwamoto M; Bowman GR; Kontur C; Bourland WA; Lynn DH; Pritchard JK; Haraguchi T; Dacks JB; Turkewitz AP
    Current Biology, Mar. 2018, Refereed, Not invited
  • Newly found Tetrahymena nucleoporins, Nup214, Nup153 and Pom121/Pom82, differentiate nuclear pore complexes of functionally distinct nuclei
    Iwamoto M; Hiraoka Y; Haraguchi T
    Communicative and Integrative Biology, 2018, Refereed, Invited
    Lead
  • Nuclear localization signal targeting to macronucleus and micronucleus in binucleated ciliate Tetrahymena thermophila
    Masaaki Iwamoto; Chie Mori; Hiroko Osakada; Takako Koujin; Yasushi Hiraoka; Tokuko Haraguchi
    GENES TO CELLS, 2018, Refereed, Not invited
    Lead
  • Function of nuclear membrane proteins in shaping the nuclear envelope integrity during closed mitosis
    Yang HJ; Iwamoto M; Hiraoka Y; Haraguchi T
    Journal of Biochemistry, Jun. 2017, Refereed, Not invited
  • An endosomal syntaxin and the AP-3 complex are required for formation and maturation of candidate lysosome-related secretory organelles (mucocysts) in Tetrahymena thermophila
    Kaur H; Sparvoli D; Osakada H; Iwamoto M; Haraguchi T; Turkewitz AP
    Molecular Biology of the Cell, Jun. 2017, Refereed, Not invited
  • Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in the ciliate Tetrahymena
    Iwamoto M; Osakada H; Mori C; Fukuda Y; Nagao K; Obuse C; Hiraoka Y; Haraguchi T
    Journal of Cell Science, May 2017, Refereed, Not invited
    Lead
  • 繊毛虫テトラヒメナの二種類の核を分ける核膜孔複合体の構造と動態
    岩本政明; 原口徳子
    藻類, 2017, Refereed, Invited
    Lead
  • Live correlative light-electron microscopy to observe molecular dynamics in high resolution
    Kobayashi S; Iwamoto M; Haraguchi T
    Microscopy, Aug. 2016, Refereed, Not invited
  • Uniquely designed nuclear structures of lower eukaryotes
    Iwamoto M; Hiraoka Y; Haraguchi T
    Current Opinion in Cell Biology, Jun. 2016, Refereed, Not invited
    Lead
  • Biased assembly of the nuclear pore complex is required for somatic and germline nuclear differentiation in Tetrahymena
    Iwamoto M; Koujin T; Osakada H; Mori C; Kojidani T; Matsuda A; Asakawa H; Hiraoka Y; Haraguchi T
    Journal of Cell Science, May 2015, Refereed, Not invited
    Lead
  • The nuclear pore complex acts as a master switch for nuclear and cell differentiation
    Iwamoto M; Hiraoka Y; Haraguchi T
    Communicative and Integrative Biology, 2015, Refereed, Not invited
    Lead
  • Uncleavable Nup98-Nup96 is functional in the fission yeast Schizosaccharomyces pombe
    Asakawa H; Mori C; Ohtsuki C; Iwamoto M; Hiraoka Y; Haraguchi T
    FEBS Open Bio, 2015, Refereed, Not invited
  • Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe
    Asakawa H; Yang HJ; Yamamoto TG; Ohtsuki C; Chikashige Y; Sakata-Sogawa K; Tokunaga M; Iwamoto M; Hiraoka Y; Haraguchi T
    Nucleus (United States), Mar. 2014, Refereed, Not invited
  • Puromycin resistance gene as an effective selection marker for ciliate Tetrahymena
    Iwamoto M; Mori C; Hiraoka Y; Haraguchi T
    Gene, Jan. 2014, Refereed, Not invited
    Lead
  • Monoclonal antibodies recognize Gly-Leu-Phe-Gly repeat of nucleoporin Nup98 of Tetrahymena, yeasts, and humans
    Iwamoto M; Asakawa H; Ohtsuki C; Osakada H; Koujin T; Hiraoka Y; Haraguchi T
    Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, Apr. 2013, Refereed, Not invited
    Lead
  • 繊毛虫 Tetrahymena thermophila の核膜孔複合体と核−細胞質間輸送
    岩本政明
    原生動物学雑誌, 2011, Refereed, Invited
  • Identification and characterization of nuclear pore complex components in Arabidopsis thaliana
    Tamura K; Fukao Y; Iwamoto M; Haraguchi T; Hara-Nishimura I
    Plant Cell, Dec. 2010, Refereed, Not invited
  • Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms
    Iwamoto M; Asakawa H; Hiraoka Y; Haraguchi T
    Genes to Cells, Jul. 2010, Refereed, Not invited
    Lead
  • Two distinct repeat sequences of Nup98 nucleoporins characterize dual nuclei in the binucleated ciliate Tetrahymena
    Iwamoto M; Mori C; Kojidani T; Bunai F; Hori T; Fukagawa T; Hiraoka Y; Haraguchi T
    Current Biology, May 2009, Refereed, Not invited
    Lead
  • 電子線トモグラフィー法を用いたテトラヒメナ細胞核構造の3次元解析
    武内 史英; 岩本 政明; 平岡 泰; 原口 徳子
    阪大複合機能ナノファウンダリ研究成果報告書, Apr. 2009, Refereed, Not invited
  • Cell volume control in Paramecium: factors that activate the control mechanisms
    Iwamoto M; Sugino K; Allen RD; Naitoh Y
    Journal of Experimental Biology, Feb. 2005, Refereed, Not invited
    Lead
  • Cell division induced by mechanical stimulation in starved Tetrahymena thermophila: Cell cycle without synthesis of macronuclear DNA
    Iwamoto M; Sugai T; Nakaoka Y
    Cell Biology International, Jul. 2004, Refereed, Not invited
    Lead
  • Uptake and rapid transfer of fluorescent ceramide analogues to acidosomes (late enclosomes) in Paramecium
    Iwamoto M; Allen RD
    Journal of Histochemistry & Cytochemictry, May 2004, Refereed, Not invited
    Lead
  • Hypo-osmotic or Ca2+-rich external conditions trigger extra contractile vacuole complex generation in Paramecium multimicronucleatum
    Iwamoto M; Allen RD; Naitoh Y
    Journal of Experimental Biology, Dec. 2003, Refereed, Not invited
    Lead
  • External GTP binding and induction of cell division in starved Tetrahymena thermophila
    Iwamoto M; Nakaoka Y
    European Journal of Cell Biology, Sep. 2002, Refereed, Not invited
    Lead
  • Activation of prostacyclin synthesis by mechanical stimulation in the ciliated protozoan Tetrahymena thermophila
    Iwamoto M; Murata T; Morii H; Watanabe Y; Nakaoka Y
    Biochemical and Biophysical Research Communications, Dec. 2000, Refereed, Not invited
    Lead
  • A macronuclear nucleoli-specific protein of the ciliate Paramecium caudatum.
    Fujishima M; Iwamoto M; Fok AK; Allen RD
    European Journal of Protistology, 1996, Refereed, Not invited

MISC

  • 分裂酵母に特異的な核膜孔複合体アウターリングの非対称性局在
    淺川東彦; 糀谷知子; 糀谷知子; 松田厚志; 楊惠如; 楊惠如; 大槻千鶴; 小坂田裕子; 岩本政明; 岩本政明; 近重祐次; 長尾恒治; 小布施力史; 平岡泰; 原口徳子; 原口徳子
    日本分子生物学会年会プログラム・要旨集(Web), 2020
  • 分裂酵母核膜孔複合体タンパク質の生細胞蛍光イメージング解析
    淺川東彦; 糀谷知子; 糀谷知子; 松田厚志; 楊惠如; 大槻千鶴; 小坂田裕子; 岩本政明; 近重裕次; 長尾恒治; 長尾恒治; 小布施力史; 小布施力史; 平岡泰; 平岡泰; 原口徳子; 原口徳子
    日本遺伝学会大会プログラム・予稿集, 2019
  • 分裂酵母に特異的な核膜孔複合体の構造と機能
    淺川東彦; 糀谷知子; 糀谷知子; 楊恵如; 大槻千鶴; 小坂田裕子; 松田厚志; 松田厚志; 岩本政明; 近重裕次; 近重裕次; 高木尚充; 長尾恒治; 長尾恒治; 小布施力史; 小布施力史; 平岡泰; 平岡泰; 原口徳子; 原口徳子
    日本分子生物学会年会プログラム・要旨集(Web), 2018
  • 分裂酵母における核膜孔複合体の構成と機能
    淺川東彦; YANG Hui-Ju; 山本孝治; 大槻千鶴; 近重裕次; 近重裕次; 十川久美子; 十川久美子; 徳永万喜洋; 徳永万喜洋; 岩本政明; 平岡泰; 平岡泰; 原口徳子; 原口徳子
    日本細胞生物学会大会要旨集, 2014
  • Organization of the nuclear pore complex in fission yeast Schizosaccharomyces pombe.
    ASAKAWA Haruhiko; CHIKASHIGE Yuji; CHIKASHIGE Yuji; OHTSUKI Chizuru; IWAMOTO Masaaki; HIRAOKA Yasushi; HIRAOKA Yasushi; HARAGUCHI Tokuko; HARAGUCHI Tokuko
    Program and Abstract Book. Annual Meeting for the Japanese Society of Developmental Biologists, 2012
  • Biased assembly of the nuclear pore complex determines nuclear differentiation in the ciliate Tetrahymena thermophila
    IWAMOTO Masaaki; KOUJIN Takako; BUNAI Fumihide; SAKADA Hiroko; MORI Chie; ASAKAWA Haruhiko; ASAKAWA Haruhiko; HIRAOKA Yasushi; HIRAOKA Yasushi; HARAGUCHI Tokuko; HARAGUCHI Tokuko
    Program and Abstract Book. Annual Meeting for the Japanese Society of Developmental Biologists, 2012
  • The nuclear pore complex leads nuclear differentiation of the macronucleus in Tetrahymena thermophila
    IWAMOTO Masaaki; KOUJIN Takako; BUNAI Fumihide; OSAKADA Hiroko; MORI Chie; KOJIDANI Tomoko; KOJIDANI Tomoko; ASAKAWA Haruhiko; HIRAOKA Yasushi; HIRAOKA Yasushi; HARAGUCHI Tokuko; HARAGUCHI Tokuko
    日本分子生物学会年会プログラム・要旨集(Web), 2011
  • Live CLEM: A new approach for observing molecular dynamics in high resolution
    HARAGUCHI Tokuko; HARAGUCHI Tokuko; KOUJIN Takako; KOJIDANI Tomoko; OSAKADA Hiroko; KOBAYASHI Shohei; IWAMOTO Masaaki; BUNAI Fumihide; ASAKAWA Haruhiko; ASAKAWA Haruhiko; CHIKASHIGE Yuji; CHIKASHIGE Yuji; HIRAOKA Yasushi; HIRAOKA Yasushi
    日本細胞生物学会大会要旨集, 2008
  • Cell volume control in Paramecium by the contractile vacuole complex and regulatory volume decrease system
    M Iwamoto; RD Allen; Y Naitoh
    MOLECULAR BIOLOGY OF THE CELL, Nov. 2002, Not refereed, Not invited

Lectures, oral presentations, etc.

  • ★The nuclear pore complexes of ciliates’ dimorphic nuclei: different structures composed of the same components.
    Iwamoto M, Osakada H, Hiraoka Y, Haraguchi T
    28 Jun. 2022, Invited
  • ★The nuclear pore complexes of ciliates’ dimorphic nuclei: different structures composed of the same components.
    Iwamoto M, Osakada H, Hiraoka Y, Haraguchi T
    28 Jun. 2022, Invited
  • ★The nuclear pore complexes of ciliates’ dimorphic nuclei: different structures composed of the same components.
    Iwamoto M, Osakada H, Hiraoka Y, Haraguchi T
    28 Jun. 2022, Invited
  • 01 Sep. 2022, Not invited
  • 01 Dec. 2021, Not invited
  • 01 Dec. 2021, Not invited
  • 22 Nov. 2021, Not invited
  • 22 Nov. 2021, Not invited
  • Basal bodies in the anterior region of the Tetrahymena cell are binding sites for nucleoporin MicNup98A.
    Yamamoto T, Fukuta N, Iwamoto M, Matsuda A
    2021 Ciliate Molecular Biology Meeting, 19 Jul. 2021, Not invited
  • 01 Sep. 2022, Not invited
  • 01 Dec. 2021, Not invited
  • 01 Dec. 2021, Not invited
  • 22 Nov. 2021, Not invited
  • 22 Nov. 2021, Not invited
  • Basal bodies in the anterior region of the Tetrahymena cell are binding sites for nucleoporin MicNup98A.
    Yamamoto T, Fukuta N, Iwamoto M, Matsuda A
    2021 Ciliate Molecular Biology Meeting, 19 Jul. 2021, Not invited
  • 01 Sep. 2022, Not invited
  • 01 Dec. 2021, Not invited
  • 01 Dec. 2021, Not invited
  • 22 Nov. 2021, Not invited
  • 22 Nov. 2021, Not invited
  • Basal bodies in the anterior region of the Tetrahymena cell are binding sites for nucleoporin MicNup98A.
    Yamamoto T, Fukuta N, Iwamoto M, Matsuda A
    2021 Ciliate Molecular Biology Meeting, 19 Jul. 2021, Not invited
  • 03 Dec. 2019, Not invited
  • 27 Oct. 2019, Not invited
  • 28 Nov. 2018, Not invited
  • 28 Nov. 2018, Not invited
  • 03 Dec. 2019, Not invited
  • 27 Oct. 2019, Not invited
  • 28 Nov. 2018, Not invited
  • 28 Nov. 2018, Not invited
  • 03 Dec. 2019, Not invited
  • 27 Oct. 2019, Not invited
  • 28 Nov. 2018, Not invited
  • 28 Nov. 2018, Not invited

Affiliated academic society

  • 日本原生生物学会
  • 日本分子生物学会
  • International Society of Protistologists

Research Themes

  • 繊毛虫核の系列分化における運命決定メカニズムの解明
    日本学術振興会, 科学研究費助成事業, Apr. 2024 - Mar. 2027
    岩本 政明
  • Molecular structures of the nuclear pore complex in Tetrahymena
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2014 - 31 Mar. 2017
    Haraguchi Tokuko; OBUSE CHIKASHI; IWAMOTO MASAAKI