Saito Yoshio

Department of Chemical Biology and Applied ChemistryProfessor

Research Keyword

  • 遺伝子診断
  • ヌクレオシド
  • 核酸化学
  • Bioorganic Chemistry

Field Of Study

  • Nanotechnology/Materials, Biochemistry, Chemistry Related to Living Systems

Award

  • 日本光医学・光生物学会奨励賞

Paper

  • Acyclic 2-ethynylnaphthalene-modified 8-aza-3,7-dideaza-2'-deoxyadenosine affords thymine discrimination by probing the DNA minor groove environment
    Y. Oku; M. Kai; S. Kobayashi; R. Katoh; Y. Saito
    Synlett, Apr. 2023, Refereed, Not invited
    Corresponding
  • FRET-based dual-labeled oligonucleotide probe detects target DNA by probing a minor groove environment
    S. Koboku; T. Tsukada; Y. Oku; S. Kobayashi; Y. Saito
    Org. Biomol. Chem., Feb. 2022, Refereed, Not invited
    Corresponding
  • 2-Ethynylnaphthalene-modified 8-aza-3,7-dideaza-2′-deoxyadenosine derivative discriminates thymine in target DNA via changes in the fluorescence wavelength
    S. Koboku; M. Yanagi; A. Funato; A. Suzuki; Y. Saito
    Tetrahedron Lett., Mar. 2020, Refereed, Not invited
    Corresponding
  • Synthesis of ethynylpyrene-modified 3-deaza-2'-deoxyguanosines as environmentally sensitive fluorescent nucleosides: target DNA-sequence detection via changes in the fluorescence wavelength (Selected as a "Front cover")
    T. Takeda; M. Yanagi; A. Suzuki; R. Katoh; Y. Saito
    Tetrahedron Lett., Mar. 2019, Refereed, Not invited
    Corresponding
  • 6-Phenylpyrrolocytidine: an intrinsically fluorescent, environmentally responsive nucleoside analogue
    S. Cho; A. Ghorbani-Choghamarani; Y. Saito; R. H. E. Hudson
    Current Protocols in Nucleic Acid Chemistry, Jan. 2019, Refereed, Not invited
  • Base-modified fluorescent purine nucleosides and nucleotides for use in oligonucleotide probes
    Y. Saito; R. H. E. Hudson
    J. Photochem. Photobiol. C: Photochemistry Reviews, Jul. 2018, Refereed, Not invited
    Lead
  • A fluorescent 3,7-bis-(naphthalen-1-ylethynylated)-2′-deoxyadenosine analogue reports thymidine in complementary DNA by a large emission Stokes shift
    Masaki Yanagi; Azusa Suzuki; Robert H. E. Hudson; Yoshio Saito
    Organic and Biomolecular Chemistry, Mar. 2018, Refereed, Not invited
  • The fluorescently responsive 3-(naphthalen1-ylethynyl)-3-deaza-2'-deoxyguanosine discriminates cytidine via the DNA minor groove
    Azusa Suzuki; Masaki Yanagi; Takuya Takeda; Robert H. E. Hudson; Yoshio Saito
    ORGANIC & BIOMOLECULAR CHEMISTRY, Oct. 2017, Refereed, Not invited
  • C2-substituted 8-aza-7-deaza-2 '-deoxyadenosines as environmentally sensitive fluorescent nucleosides for discriminating apurinic/apyrimidinic sites in DNA duplex
    Takumi Yamauchi; Takuya Takeda; Masaki Yanagi; Noriki Takahashi; Azusa Suzuki; Yoshio Saito
    TETRAHEDRON LETTERS, Jan. 2017, Refereed, Not invited
  • Design and synthesis of a novel fluorescent benzo[g]imidazo[4,5-c]quinoline nucleoside for monitoring base-pair-induced protonation with cytosine (Selected as a "Hot article")
    S. Siraiwa; A. Suzuki; R. Katoh; Y. Saito
    Org. Biomol. Chem., Apr. 2016, Refereed, Not invited
    Corresponding
  • Design and synthesis of environmentally sensitive fluorescent 2-naphthylethynylated 2 '-deoxyadenosines: Detection of target DNA via changes in fluorescence intensity and wavelength
    Azusa Suzuki; Ryota Kozakai; Tatsuya Aso; Isao Saito; Takuya Takeda; Yoshio Saito
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jan. 2016, Refereed, Not invited
  • Design and synthesis of 7-naphthyl-8-aza-7-deaza-2'-deoxyadenosines as environmentally sensitive fluorescent nucleosides
    Y. Saito; A. Suzuki; T. Yamauchi; I. Saito
    Tetrahedron Lett., Memorial Symposium-in-Print for Harry Wasserman, May 2015, Refereed, Not invited
    Lead
  • Synthesis of 8-aza-3,7-dideaza-2 '-deoxyadenosines possessing a new adenosine skeleton as an environmentally sensitive fluorescent nucleoside for monitoring the DNA minor groove
    Azusa Suzuki; Mio Saito; Ryuzi Katoh; Yoshio Saito
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, Refereed, Not invited
  • Synthesis and photophysical properties of pyrene-labeled 3-deaza-2 '-deoxyadenosines comprising a non-pi-conjugated linker: fluorescence quenching-based oligodeoxynucleotide probes for thymine identification
    Tatsuya Aso; Koichiro Saito; Azusa Suzuki; Yoshio Saito
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, Refereed, Not invited
  • Development of environmentally sensitive fluorescent 3-deaza-2'-deoxyadenosine derivatives and their applications to DNA probe
    A. Suzuki; I. Saito; Y. Saito
    Photomed. Photobiol., Dec. 2014, Not refereed, Not invited
    Corresponding
  • Molecular design of an environmentally sensitive fluorescent nucleoside, 3-deaza-2'-deoxyadenosine derivative: Distinguishing thymine by probing the DNA minor groove (Selected as an "Inside cover")
    A. Suzuki; T. Yanaba; I. Saito; Y. Saito
    ChemBioChem, Jul. 2014, Refereed, Not invited
    Corresponding
  • Design of an environmentally sensitive fluorescent 8-aza-7-deaza-2 '-deoxyadenosine derivative with dual fluorescence for the specific detection of thymine
    Azusa Suzuki; Nobukatsu Nemoto; Isao Saito; Yoshio Saito
    ORGANIC & BIOMOLECULAR CHEMISTRY, Jan. 2014, Refereed, Not invited
  • Synthesis of solvatofluorochromic 7-arylethynylated 7-deaza-2'-deoxyadenosine derivatives: Application to the design of environmentally sensitive fluorescent probes forming stable DNA duplexes
    A. Suzuki; K. Kimura; S. Ishioroshi; I. Saito; N. Nemoto; Y. Saito
    Tetrahedron Lett., Mar. 2013, Refereed, Not invited
    Corresponding
  • Naphthalene-based environmentally sensitive fluorescent 8-substituted 2'-deoxyadenosines: Application to DNA detection
    A. Suzuki; N. Takahashi; Y. Okada; I. Saito; N. Nemoto; Y. Saito
    Bioorg. Med. Chem. Lett., Feb. 2013, Refereed, Not invited
    Corresponding
  • An environmentally sensitive fluorescent purine nucleoside that changes emission wavelength upon hybridization
    Yoshio Saito; Azusa Suzuki; Yuji Okada; Yuki Yamasaka; Nobukatsu Nemoto; Isao Saito
    CHEMICAL COMMUNICATIONS, 2013, Refereed, Not invited
  • Drastic enhancement of excess electron-transfer efficiency through DNA by inserting consecutive 5-phenylethynyl-2'-deoxyuridines as a modulator
    M. Tanaka; K. Oguma; Y. Saito; I. Saito
    Chem.Commun., Aug. 2012, Refereed, Not invited
  • Enhancement of fluorescence quenching and exciplex formation in DNA major groove by double incorporation of modified fluorescent deoxyuridines
    M. Tanaka; K. Oguma; Y. Saito; I. Saito
    Bioorg. Med. Chem. Lett., May 2012, Refereed, Not invited
    Corresponding
  • Fluorometric detection of adenine in target DNA by exciplex formation with fluorescent 8-arylethynylated deoxyguanosine
    Y. Saito; K. Kugenuma; M. Tanaka; A. Suzuki; I. Saito
    Bioorg. Med. Chem. Lett., Apr. 2012, Refereed, Not invited
    Lead
  • Fluorescent nucleosides with ‘on-off’ switching function, pH-responsive fluorescent uridine derivatives
    Y. Saito; S. Miyamoto; A. Suzuki; K. Matsumoto; T. Ishihara; I. Saito
    Bioorg. Med. Chem. Lett., Mar. 2012, Refereed, Not invited
    Lead
  • Expansion of the genetic alphabet: Unnatural nucleobases and their applications
    Subhendu Sekhar Bag; Jennifer M. Heemstra; Yoshio Saito; David M. Chenoweth
    Journal of Nucleic Acids, 2012, Refereed, Not invited
  • Stabilization of DNA duplex by 2-substituted adenine as a minor groove modifier
    M. Tanaka; R. Kozakai; Y. Saito; I. Saito
    Bioorg. Med. Chem. Lett., Sep. 2011, Refereed, Not invited
    Corresponding
  • Synthesis and photophysical properties of novel push-pull-type solvatochromic 7-deaza-2'-deoxypurine nucleosides
    Y. Saito; A. Suzuki; S. Ishioroshi; I. Saito
    Tetrahedron Lett., Jul. 2011, Refereed, Not invited
    Lead
  • Design and application of novel nucleobase analogs as an environmentally sensitive probe
    M. Tanaka; K. Oguma; R. Kozakai; K. Kugenuma; Y. Saito; I. Saito
    Photomed. Photobiol., May 2011, Not refereed, Not invited
    Corresponding
  • 環境感応型蛍光核酸の開発と蛍光DNAプローブへの応用
    Y. Saito
    光化学, Apr. 2011, Not refereed, Not invited
    Lead
  • Design and Synthesis of Highly Solvatochromic Fluorescent 2'-Deoxyguanosine and 2'-Deoxyadenosine Analogs
    K. Matsumoto; N. Takahashi; A. Suzuki; T. Morii; Y. Saito; I. Saito
    Bioorg. Med. Chem. Lett., Mar. 2011, Refereed, Not invited
    Corresponding
  • Synthesis of environmentally sensitive 2'-deoxyguanosine containing solvatochromic pyrene fluorophore
    Y. Saito; Y. Shinohara; S. Ishioroshi; A. Suzuki; M. Tanaka; I. Saito
    Tetrahedron Lett., Mar. 2011, Refereed, Not invited
    Lead
  • Synthesis and photophysical properties of 8-arylbutadienyl 2'-deoxyguanosines
    Y. Saito; M. Koda; Y. Shinohara; I. Saito
    Tetrahedron Lett., Feb. 2011, Refereed, Not invited
    Lead
  • Design of ends free and self-quenched molecular beacons
    Y. Saito; A. Suzuki; K. Matsumoto; I. Saito
    Photomed. Photobiol., Dec. 2010, Not refereed, Not invited
    Lead
  • Singly and doubly labeled base-discriminating fluorescent oligonucleotide probes containing oxo-pyrene chromophore
    S. S. Bag; R. Kundu; K. Matsumoto; Y. Saito; I. Saito
    Bioorg. Med. Chem. Lett., Apr. 2010, Refereed, Not invited
  • Synthesis of Novel Push-Pull Type Solvatochromic 2'-Deoxyguanosine Derivatives with Longer Wavelength Emission
    Y. Saito; A. Suzuki; K. Imai; N. Nemoto; I. Saito
    Tetrahedron Lett., Mar. 2010, Refereed, Not invited
    Lead
  • Design of Environmentally Sensitive Fluorescent 2'-Deoxyguanosine Containing Arylethynyl Moieties: Distinction of Thymine Base by Base-Discriminating Fluorescent (BDF) Probe
    Y. Shinohara; K. Matsumoto; K. Kugenuma; T. Morii; Y. Saito; I. Saito
    Bioorg. Med. Chem. Lett., Mar. 2010, Refereed, Not invited
    Corresponding
  • A Probe Containing Two Base-discriminating Fluorescent (BDF) Nucleosides for SNP Typing
    Y. Yoshida; K. Niwa; K. Yamada; M. Tokeshi; Y. Baba; Y.Saito; A. Okamoto; I. Saito
    Chem. Lett., Feb. 2010, Refereed, Not invited
  • Light Energy Induced Fluorescence Switching Based on Novel Photochromic Nucleosides
    K. Matsumoto; Y. Saito; I. Saito; T. Morii
    Green Energy and Technology, 2010, Refereed, Not invited
  • Pyrene-labeled deoxyguanosine as a fluorescence sensor to discriminate single and double stranded DNA structures: Design of ends free molecular beacons
    K. Matsumoto; Y. Shinohara; S. S. Bag; Y. Takeuchi; T. Morii; Y. Saito; I. Saito
    Bioorg. Med. Chem. Lett., Sep. 2009, Refereed, Not invited
    Corresponding
  • Design of extremely facile 3'- and 5'- ends free molecular beacons using C8 alkylamino substituted 2'-deoxyguanosine
    K. Matsumoto; Y. Shinohara; S. S. Bag; Y. Takeuchi; T. Morii; Y. Saito; I. Saito
    Nucleic Acids Symp. Ser., Sep. 2009, Not refereed, Not invited
    Corresponding
  • Photo-switching of vinylpyrene-substituted 2'-deoxyguanosine and its application
    Y. Saito; Y. Takeuchi; K. Matsumoto; N. Takahashi; A. Suzuki; I. Saito
    Nucleic Acids Symp. Ser., Sep. 2009, Not refereed, Not invited
    Lead
  • Ends free and self-quenched molecular beacon with pyrene labeled pyrrolocytidine in the middle of the stem
    Y. Saito; Y. Shinohara; S. S. Bag; Y. Takeuchi; K. Matsumoto; I. Saito
    Tetrahedron, Sep. 2009, Refereed, Not invited
    Lead
  • Fluorescence switching of photochromic vinylpyrene-substituted 2'-deoxyguanosine
    Yoshio Saito; Katsuhiko Matsumoto; Yoshiki Takeuchi; Subhendu Sekhar Bag; Satoshi Kodate; Takashi Morii; Isao Saito
    Tetrahedron Lett., Sep. 2009, Refereed, Not invited
    Lead
  • Anthracene based base-discriminating fluorescent oligonucleotide probes for SNPs typing: Synthesis and photophysical properties
    Y. Saito; K. Motegi; S. S. Bag; I. Saito
    Bioorg. Med. Chem., 2008, Refereed, Not invited
    Lead
  • C8-alkynyl- and alkylamino substituted 2'-deoxyguanosines: A universal linker for nucleic acids modification
    Y. Saito; K. Matsumoto; S. S. Bag; S. Ogasawara; K. Fujimoto; K. Hanawa; I. Saito
    Tetrahedron, 2008, Refereed, Not invited
    Lead
  • Fluorometric sensing of conformational switching of DNA; The use of fluorescence labeled C8-alkylamino substituted 2'-deoxyguanosine
    K. Matsumoto; S. S. Bag; A. Misawa; I. Saito
    Nucleic Acids Symp. Ser., 2008, Not refereed, Not invited
    Lead
  • Design of an efficient self-quenched molecular beacon for SNPs genotyping
    K. Numajiri; S. S. Bag; E. Mizuno; I. Saito
    Nucleic Acids Symp. Ser., 2008, Not refereed, Not invited
    Lead
  • Design of Practically Important Fluorescent Molecules for SNP Genotyping –Ends Free and Quencher Free Molecular Beacons-
    Y. Shinohara; S. S. Bag; Y. Takeuchi; E. Mizuno; K. Numajiri; K. Matsumoto; I. Saito
    Nucleic Acids Symp. Ser., 2008, Not refereed, Not invited
    Lead
  • Dual-labeled oligonucleotide probe for sensing adenosine via FRET: A novel alternative to SNPs genotyping
    Y. Saito; S. S. Bag; K. Kusakabe; C. Nagai; K. Matsumoto; E. Mizuno; S. Kodate; I. Suzuka; I. Saito
    Chem. Commun., 2007, Refereed, Not invited
    Lead
  • Synthesis of C8-alkylamino substituted 2'-deoxyguanosine
    K. Matsumoto; S. S. Bag; S. Ogasawara; I. Suzuka; I. Saito
    Nucleic Acids Symp. Ser., 2007, Not refereed, Not invited
    Lead
  • Design of dual-labeled oligonucleotide probes for SNPs genotyping
    S. S. Bag; S. Kodate; I. Suzuka; I. Saito
    Nucleic Acids Symp. Ser., 2007, Not refereed, Not invited
    Lead
  • Design of a novel G-quenched molecular beacon: A simple and efficient strategy for DNA sequence analysis
    E. Mizuno; S. S. Bag; I. Suzuka; I. Saito
    Chem. Commun., 2007, Refereed, Not invited
    Lead
  • 高精度DNAチップのための塩基識別型蛍光性核酸塩基(BDF塩基)の開発
    Y. Saito; A. Okamoto; I. Saito
    BIO INDUSTRY, 2006, Not refereed, Not invited
    Lead
  • Synthesis of pyrene-labeled base-discriminating fluorescent (BDF) nucleoside and its fluorescence properties
    S. S. Bag; Y. Saito; K. Hanawa; K. Hayashi; S. Kodate; I. Suzuka; I. Saito
    Nucleic Acids Symp. Ser., 2006, Not refereed, Not invited
  • Synthesis and properties of acridone-labeled base-discriminating fluorescent (BDF) nucleosides
    Y. Saito; K. Hanawa; S. S. Bag; K. Motegi; I. Saito
    Nucleic Acids Symp. Ser., 2006, Not refereed, Not invited
    Lead
  • Luminescence properties of dual fluorescent pyrene derivatives used as DNA probe molecule
    S. Kodate; H. Wada; I. Suzuka; A. Okamoto; K. Tainaka; Y. Saito; I. Saito
    Nucleic Acids Symp. Ser., 2006, Not refereed, Not invited
  • High selective fluorescent nucleobases for designing base-discriminating fluorescence probe useful for homogeneous SNP typing
    I. Saito; Y. Saito; K. Hanawa; K. Hayashi; K. Motegi; S. S. Bag; C. Dohno; A. Okamoto
    Pure Appl. Chem., 2006, Refereed, Not invited
  • Intelligent fluorescent nucleoside in sensing cytosine base: Importance of hydrophobic nature of perylene fluorophore
    S. S. Bag; Y. Saito; K. Hanawa; S. Kodate; I. Suzuka; I. Saito
    Bioorg. Med. Chem. Lett., 2006, Refereed, Not invited
  • Acridone Labeled Base-discriminating Fluorescence (BDF) Nucleoside: Synthesis and Their Photophysical Properties
    Y. Saito; K. Hanawa; N. Kawasaki; S. S. Bag; I. Saito
    Chem. Lett., 2006, Refereed, Not invited
    Lead
  • Design of highly selective fluorescent nucleobases for SNP typing: Base-discriminating fluorescent (BDF) probe
    Saito, I; Y Saito; A Okamoto; T Ichiba; K Kanatani; K Tainaka
    Chemistry of Nucleic Acid Components, 2005, Refereed, Not invited
  • Template-directed photoreversible ligation of DNA via 7-carboxyvinyl-7-deaza-2'-doxyadenosine
    I. Saito; Y. Miyauchi; Y. Saito; K. Fujimoto
    Tetrahedron Lett., 2005, Refereed, Not invited
  • Synthesis and properties of novel base-discriminating fluorescent (BDF) nucleosides
    Y. Saito; K. Hanawa; K. Hayashi; K. Motegi; A. Okamoto; I. Saito
    Nucleic Acids Symp. Ser., 2005, Not refereed, Not invited
    Lead
  • Design of base-discriminating fluorescent nucleosides
    A. Okamoto; Y. Saito; I. Saito
    J. Photochem. Photobiol. C: Photochemistry Reviews, 2005, Refereed, Not invited
  • Synthesis and properties of purine-type base-discriminating fluorescent (BDF) nucleosides: Distinction of thymine by fluorescence-labeled deoxyadenosine
    Y. Saito; K. Hanawa; K. Motegi; K. Omoto; A. Okamoto; I. Saito
    Tetrahedron Lett., 2005, Refereed, Not invited
    Lead
  • A novel fluorescent guanine derivatives distinguishable of three structures, single strand, duplex, and quadruplex
    A. Okamoto; K. Kanatani; Y. Ochi; Y. Saito; I. Saito
    Tetrahedron Lett., 2004, Refereed, Not invited
  • Base-discriminating fluorescent (BDF) nucleoside: distinction of thymine by fluorescence quenching
    Y. Saito; Y. Miyauchi; A. Okamoto; I. Saito
    Chem. Commun., 2004, Refereed, Not invited
    Lead
  • Synthesis and properties of novel base-discriminating fluorescent (BDF) nucleosides: A highly polarity-sensitive fluorophore for SNP typing
    Y. Saito; Y. Miyauchi; A. Okamoto; I. Saito
    Tetrahedron Lett., 2004, Refereed, Not invited
    Lead
  • Design of base-discriminating fluorescent (BDF) nucleobase for SNP typing
    Y. Saito; K.Kanatani; Y. Ochi; A. Okamoto; I. Saito
    Nucleic Acids Symp. Ser., 2004, Not refereed, Not invited
    Lead
  • Fluorescence properties of DNA probes multiply labeled by a base-discriminating fluorescent nucleobase, PyU
    A. Okamoto; K. Kanatani; Y. Saito; I. Saito
    Photomed. Photobiol., 2004, Not refereed, Not invited
  • Liquid chromatographic separation of phosphoramidate diastereomers on a polysaccharide-type chiral stationary phase
    N. Mesplet; Y. Saito; P. Morin; L. A. Agrofoglio
    J. Chromatogr. A, 2003, Refereed, Not invited
  • Palladium-assisted route to nucleosides
    L. A. Agrofoglio; I. Gillaizeau; Y. Saito
    Chem. Rev., 2003, Refereed, Not invited
  • Synthesis of 1,2,3-triazolo-carbanucleoside analogues of ribavirin targeting an HCV in replicon
    Y. Saito; V. Escuret; D. Durantel; F. Zoulim; R.F. Schinazi; L.A. Agrofoglio
    Bioorg. Med. Chem., 2003, Refereed, Not invited
    Lead
  • HPLC and mass spectrometry analysis of the enzymatic hydrolysis of anti-HIV pronucleotide diastereomers
    N. Mesplet; Y. Saito; P. Morin; L. A. Agrofoglio
    Bioorg. Chem., 2003, Refereed, Not invited
  • Chemical synthesis of 13C labeled anti-HIV nucleosides as mass-internal standards
    Y. Saito; T. A. Zevaco; L. A. Agrofoglio
    Tetrahedron, 2002, Refereed, Not invited
    Lead
  • Synthesis of carbocyclic phosphononucleosides
    B. Legeret; Z. Sarakauskaite; F. Pradaux; Y. Saito; S. Tumkevicius; L. A. Agrofoglio
    Nucleosides, Nucleotides, Nucleic Acids, 2001, Not refereed, Not invited
  • Synthesis of sugar-modified derivatives of the unusual nucleoside oxanosine and its carbocyclic analogs as potential inhibitors of HIV
    Y. Saito; M. Nakamura; T. Ohno; C. Chaicharoenpong; E. Ichikawa; S. Yamamura; K. Kato; K. Umezawa
    J. Chem. Soc., Perkin Trans. 1, 2001, Refereed, Not invited
    Lead
  • Synthesis of carbocyclic phosphononucleosides
    B. Legeret; Z. Sarakauskaite; F. Pradaux; Y. Saito; S. Tumkevicius; L. A. Agrofoglio
    Nucleosides, Nucleotides, Nucleic Acids, 2001, Not refereed, Not invited
  • Efficient synthesis of D-[1'-13C]ribonucleosides for incorporation into oligo-RNA
    Y. Saito; A. Nyilas; L. A. Agrofoglio
    Nucleosides, Nucleotides, Nucleic Acids, 2001, Not refereed, Not invited
    Lead
  • Synthesis of isotopically labeled D-[1'-13C]ribonucleoside phosphoramidites
    Y. Saito; A. Nyilas; L. A. Agrofoglio
    Carbohydrate Res., 2001, Refereed, Not invited
    Lead
  • Inhibition of acidic sphingomyelinase by xanthone compound isolated from Garcinia Speciosa
    C. Okudaira; Y. Ikeda; S. Kondo; S. Furuya; Y. Hirabayashi; T. Koyano; Y. Saito; K. Umezawa
    J. Enzyme inhibition, 2000, Refereed, Not invited
  • Phosphatidylinositol 4-kinase assay in ovarian carcinoma cells
    S. Isonishi; A. Okamoto; K. Ochiai; Y. Saito; K. Umezawa
    Methods in Molecular Medicine, 2000, Not refereed, Not invited
  • Syntheses of oxanosine and carbocyclic oxanosine derivatives as anti-HIV agents
    Y. Saito; M. Nakamura; T. Ohno; C. Chaicharoenpong; E. Ichikawa; S. Yamamura; K. Kato; K. Umezawa
    J. Antibiotics, 2000, Refereed, Not invited
    Lead
  • Synthesis and inhibitory activity against phosphatidylinositol 4-kinase of echiguanine analogs
    Y. Saito; K. Kato; K. Umezawa
    Nucleosides, Nucleotides, 1999, Not refereed, Not invited
    Lead
  • Synthesis and anti-HIV activity of unusual nucleoside oxanosine derivatives
    Y. Saito; C. Chaicharoenpong; O. Ohno; E. Ichikawa; S. Yamamura; K. Kato; M. Nakamura; T. Ohno; K. Umezawa
    Nucleic Acids Symp. Ser., 1999, Not refereed, Not invited
    Lead
  • Synthetic study on a 26-membered macrolide, amphidinolide B: Synthesis of the C-1-C-13 fragment
    K Ohi; K Shima; K Hamada; Y Saito; N Yamada; S Ohba; S Nishiyama
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Oct. 1998, Refereed, Not invited
  • Synthesis and structure-activity relationship of ribofuranosyl echiguanine analogs as inhibitors of phosphatidylinositol 4-kinase
    Y. Saito; K. Kato; K. Umezawa
    Tetrahedron, 1998, Refereed, Not invited
  • Synthesis of echiguanine analogs and their ribofuranosyl glycosides that inhibit phosphatidylinositol 4-kinase
    Y Saito; K Umezawa; K Kato
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Apr. 1997, Refereed, Not invited
  • Synthesis of echiguanine analogs and their ribofuranosyl glycosides that inhibit phosphatidylinositol 4-kinase
    Y. Saito; K. Kato; K. Umezawa
    Nucleic Acids Symp. Ser., 1997, Not refereed, Not invited
    Lead
  • Synthesis of ribofuranosyl glycosides of echiguanines A and B, inhibitors of phosphatidylinositol 4-kinase
    K. Sanpei; Y. Saito; M. Imoto; K. Umezawa; K. Kato
    Bioorg. Med. Chem. Lett., 1996, Refereed, Not invited

MISC

  • Design and synthesis of fluorescent oligodeoxyribonucleotides sensitive to the micro environmental change in polarity
    K. Matsumoto; Y. Saito; T. Morii; I. Saito
    The 2nd International Symposium Kyoto University Global COE Program, Uji, 2010.8.19-20, 2010, Refereed, Not invited
  • Design of an ultimate quencher free molecular beacon containing pyrrocytidine-guanine base pair.
    齋藤 烈; Y. Saito; Y. Shinohara; S. S. Bag; Y. Takeuchi; K. Matsumsoto; I. Saito
    Nucleic Acids Symp. Ser, 2008, Not refereed, Not invited

Books and other publications

  • 核酸科学ハンドブック(日本核酸化学会) 第II部 25. 遺伝子チップ
    Joint work, 473-477
    講談社, Dec. 2020, Not refereed
    9784065207864
  • Modified Nucleic Acids (Nucleic Acids and Molecular Biology Vol. 31)
    Y. Saito; A. Suzuki; I. Saito, Contributor, Chapter 2, Y. Saito; A. Suzuki; I. Saito
    Springer, Apr. 2016, Not refereed
  • ゲノム化学
    齋藤義雄; 齋藤烈, Joint work, 第7章, 齋藤義雄、齋藤烈
    化学同人, Mar. 2007, Not refereed

Lectures, oral presentations, etc.

  • Design and synthesis of environmentally sensitive fluorescent 7-deaza-2,8-diazaadenosine derivatives
    Takumi Tsukada; Subaru Kakegawa; Takumi Yamauchi; Yoshio Saito
    第49回国際核酸化学シンポジウム, Nov. 2022, Not invited
  • Synthesis and photophysical properties of novel fluorescent DNA probes containing bis- pyrene unit for target DNA detection
    Saika Kobayashi; Yanagi Masaki; Katsuhiko Matsumoto; Yoshio Saito
    2022年 第49回国際核酸化学シンポジウム, Nov. 2022, Not invited
  • Design and synthesis of novel fluorescent DNA probes containing bis-pyrene unit for DNA detection
    小林彩夏; 柳昌樹; 松本桂彦; 齋藤義雄
    令和4年度 化学系学協会東北大会, Sep. 2022, Not invited
  • Synthesis and photophysical properties of novel acyclic ESF nucleoside
    Y. Oku; N. Abiko; Y. Saito
    日本化学会第102春季年会, Mar. 2022, Not invited
  • Design of novel environmentally sensitive fluorescence nucleosides containing,7-deaza-2,8-diazaadenine skeleton
    T. Tsukada; S. Kakegawa; T. Yamauchi; Y. Saito
    日本化学会第102春季年会, Mar. 2022, Not invited
  • Development of novel fluorescent DNA probes possessing bis-pyrene unit for target DNA detection
    S. Kobayashi; M. Yanagi; K. Matsumoto; Y. Saito
    日本化学会第102春季年会, Mar. 2022, Not invited
  • Development of novel FRET-based oligonucleotide probes for target DNA detection
    Y. Oku; S. koboku; Y. Saito
    The 48th International Symposium on Nucleic Acids Chemistry, Nov. 2021, Not invited
  • FRETを利用した新規8-アザ-3,7-ジデアザアデノシン誘導体の合成とDNAプローブへの応用
    奥 友里乃; 小木 聖徳; 塚田 匠; 齋藤 義雄
    2021年度化学系学協会東北大会, Oct. 2021, Not invited
  • 8-アザ-3,7-ジデアザアデニン骨格を有する新規環境感応型蛍光PNAプローブの開発
    小林彩夏、渡辺大地、岡部早矢加、齋藤義雄
    2021年度化学系学協会東北大会, Oct. 2021, Not invited
  • 糖部位がフレキシブルな環境感応型蛍光ヌクレオシドの合成と光学特性
    塚田匠、小木聖徳、齋藤義雄
    2021年度化学系学協会東北大会, Oct. 2021, Not invited
  • Design and photophysical properties of dual-labelled oligonucleotide probes for DNA ,detection
    Y. Oku; S. koboku; Y. Saito
    有機合成化学夏季国際セミナー, Sep. 2021, Not invited
  • C3位に1-フェニルナフタレンを含む8-アザ-3,7-ジデアザ-2′-デオキシアデノシン誘導体の合成と光学特性
    船戸彩加、一色田萌衣、塚田匠、小林彩夏、齋藤義雄
    日本化学会第101春季年会, Mar. 2021, 日本化学会, Not invited
  • 2-ナフトナトリルを含む環境感応型8-アザ-3,7-ジデアザ-2′-デオキシアデノシン誘導体の合成と蛍光核酸プローブへの応用
    奥友里乃、小木聖徳、齋藤義雄
    日本化学会第101春季年会, Mar. 2021, 日本化学会, Not invited
  • C3位に2-ナフトニトリルを含む8-アザ-3,7-ジデアザ-2′-デオキシアデノシンの開発と応用
    小木聖徳、柳昌樹、鈴木梓、齋藤義雄
    2020年度化学系学協会東北大会, Sep. 2020, Not invited
  • 1-フェニルナフタレンを導入した8-アザ-3,7-ジデアザ-2′-デオキシアデノシン誘導体の合成と光学特性
    船戸彩加、桑原健、小木聖徳、齋藤義雄
    2020年度化学系学協会東北大会, Sep. 2020
  • C3位に2-ナフトニトリルを含む8-アザ-3,7-ジデアザ-2-デオキシアデノシン誘導体の光学特性とDNAプローブへの応用
    小木聖徳、柳昌樹、鈴木梓、齋藤義雄
    2020年光化学討論会, Sep. 2020, 光化学協会, Not invited
  • フェニルナフタレンを含む8-アザ-3,7-ジデアザアデニン誘導体の光学特性
    船戸彩加、桑原健、小木聖徳、齋藤義雄
    2020年光化学討論会, Sep. 2020, 光化学協会, Not invited
  • Design and synthesis of solvatochromic 3-deaza-2’-deoxyguanosine derivatives: distinction of cytosine by probing the DNA minorgroove
    S. Koboku; M. Yanagi; A. Suzuki; Y. Saito
    The 46th International Symposium on Nucleic Acids Chemistry, Oct. 2019, Not invited
  • 8-アザ-3,7-ジデアザアデニン骨格を有する新規蛍光ヌクレオシドの合成と光学特性
    小木聖徳、船戸彩加、桑原健、齋藤義雄
    2019年度化学系学協会東北大会, Sep. 2019, Not invited
  • 3-デアザ-2'-デオキシグアノシン誘導体を含む環境感応型蛍光DNAプローブの開発
    小木聖徳、柳昌樹、鈴木梓、齋藤義雄
    2019年光化学討論会, Sep. 2019, Not invited
  • Synthesis of 3-(naphthalen-1-ylethynyl)-3-deaza-2’-deoxyguanosine as an environmentally sensitive fluorescent nucleoside
    小木聖徳、柳昌樹、鈴木梓、齋藤義雄
    日本化学会第99春季年会, Mar. 2019, Not invited
  • Development of a novel fluorescent benzo[g]imidazo[4,5-c]quinoline nucleoside for monitoring base-pair-induced protonation with cytosine
    Development of a novel fluorescent benzo[g]imidazo[4; 5-c]quinoline nucleoside for monitoring base-pair-induced protonation with cytosine
    平成30年度化学系学協会東北大会, Sep. 2018, Not invited
  • 新規蛍光性ベンゾイミダゾキノリンヌクレオシドのデザインと光学特性
    柳昌樹、白岩昭吾、齋藤義雄
    2018年光化学討論会, Sep. 2018, Not invited
  • Development of fluorescent benzo[g]imidazo[4,5-c]quinoline nucleoside for monitoring base-pair-induced protonation with cytosine: Distinguishing cytosine via changes in fluorescence intensity and wavelength
    Y. Saito; S. Siraiwa; M. Yanagi
    XXIII International Round Table on Nucleosides, Nucleotides & Nucleic Acids, Aug. 2018, Not invited
  • 8-アザ-7-デアザ-2'-デオキシアデノシン誘導体を含む環境感応型蛍光DNAプローブの開発
    柳昌樹、白岩昭吾、齋藤義雄
    第29回万有仙台シンポジウム, Jun. 2018, Not invited
  • Enviromentally sensitive fluorescent purine nucleosides for discriminating AP sites in DNA duplex
    M. Yanagi; T. Yamauchi; N. Nemoto; Y. Saito
    The 44th International Symposium on Nucleic Acids Chemistry, Nov. 2017, Not invited
  • 新規蛍光性8-アザ-7-デアザ-2'-デオキシアデノシン誘導体を用いたDNA配列の識別
    柳昌樹、山内拓史、根本修克、齋藤義雄
    2017年光化学討論会, Sep. 2017, Not invited
  • Design and synthesis of C2-substituted 8-aza-7-deaza-2’-deoxyadenosines as environmentally sensitive fluorescent nucleosides
    Y. Saito; M. Yanagi
    254th American Chemical Society National Meeting &Exposition, Aug. 2017, Not invited
  • 8-アザ-7-デアザ-2'-デオキシアデノシン誘導体を含む環境感応型蛍光DNAプローブの開発
    柳昌樹、山内拓史、武田拓也、齋藤義雄
    日本化学会第97春季年会, Mar. 2017, Not invited
  • 蛍光消光を利用した3-デアザアデニン骨格を含むチミン塩基識別DNAプローブの開発
    武田拓也、阿相達也、齋藤義雄
    日本化学会第97春季年会, Mar. 2017, Not invited
  • Design of pyrene-labeled 3-deaza-2’-deoxyadenosines comprising a non-π-conjugated linker: Novel fluorescence quenching-based oligodeoxynucleotide probes
    Y. Saito; T. Takeda; T. Aso; M. Yanagi; N. Takahashi
    Asian Photochemistry Conference (APC) 2016, Dec. 2016, Not invited
  • Design of novel fluorescence quenching-based ODN probes for SNPs genotyping
    Y. Saito; T. Takeda; T. Aso; M. Yanagi; N. Takahashi
    The 43rd International Symposium on Nucleic Acids Chemistry, Sep. 2016, Not invited
  • Synthesis of fluorescence quenching-based ODN probes for SNPs genotyping
    武田拓也、阿相達也、柳昌樹、高橋知希、齋藤義雄
    平成28年度化学系学協会東北大会, Sep. 2016, Not invited
  • Synthesis and photophysical properties of environmentally sensitive fluorescent purine nucleosides
    平成28年度化学系学協会東北大会, Sep. 2016, Invited
  • ピレンの蛍光消光を利用したチミン塩基識別プローブの開発
    武田拓也、阿相達也、柳昌樹、高橋知希、齋藤義雄
    2016年光化学討論会, Sep. 2016, Not invited
  • Design and synthesis of pyrene-labeled 3-deaza-2’-deoxyadenosine derivatives comprising a non-π-conjugated linker: distinction of thymine by fluorescence quenching
    Y. Saito; T. Aso; T. Takeda
    XXII International Round Table on Nucleosides, Nucleotides & Nucleic Acids, Jul. 2016, Not invited
  • Synthesis and photophysical properties of an environmentally sensitive fluorescent nucleoside possessing 8-aza-3,7-dideazaadenine skeleton for monitoring DNA minor groove
    Y. Saito; A. Suzuki; M. Saito
    XXVIth IUPAC Symposium on Photochemistry, Apr. 2016, Not invited
  • 8-アザ-3,7-ジデアザアデニン骨格を有する新規蛍光性ヌクレオシドの開発とチミン塩基識別プローブへの応用
    鈴木梓、山内拓史、武田拓也、齋藤義雄
    日本化学会第96春季年会, Mar. 2016, Not invited
  • Development of an environmentally sensitive fluorescent nucleoside possessing 8-aza-3,7-dideazaadenine skeleton for monitoring DNA minor groove
    A. Suzuki; M. Saito; Y. Saito
    The 42nd International Symposium on Nucleic Acids Chemistry, Sep. 2015, Not invited
  • Synthesis and photophysical properties of C7-naphthylated 8-aza-7-deaza-2'-deoxyadenines as environmentally sensitive fluorescent nucleoside
    T. Takeda; A. Imaizumi; A. Suzuki; Y. Saito
    The 42nd International Symposium on Nucleic Acids Chemistry, Sep. 2015, Not invited
  • 7-ナフチル-8-アザ-7-デアザ-2'-デオキシアデノシン誘導体を含むDNAプローブの合成
    山内拓史、鈴木梓、齋藤義雄
    平成27年度化学系学協会東北大会, Sep. 2015, Not invited
  • Fluorescence properties of violanthrene A and B crystals
    佐藤憲幸、鈴木梓、齋藤義雄、関根あき子、加藤隆二
    平成27年度化学系学協会東北大会, Sep. 2015, Not invited
  • 8-アザ-3,7-ジデアザアデニン骨格を有する環境感応型蛍光性ヌクレオシドの開発とDNAプローブへの応用
    鈴木梓、齋藤未生、齋藤義雄
    2015年光化学討論会, Sep. 2015, Not invited
  • 8-アザ-7-デアザアデニンの7位にナフチル基を有する新規蛍光性核酸の光学特性
    鈴木梓、山内拓史、齋藤義雄
    2015年光化学討論会, Sep. 2015, Not invited
  • Synthesis and photophysical properties of environmentally sensitive 7-naphthyl-8-aza-7-deaza-2'-deoxyadenosines
    Y. Saito; A. Suzuki
    27th International Conference on Photochemistry, Jul. 2015, Not invited
  • 7位にナフチル基を有する環境感応型蛍光性8−アザ−7-デアザ−2'-デオキシアデノシンの開発とチミン塩基識別プローブへの応用
    鈴木梓、齋藤烈、齋藤義雄
    第37回日本光医学・光生物学会, Jul. 2015, Not invited
  • Design and synthesis of environmentally sensitive dual fluorescent nucleosides
    Y. Saito
    The 11th Korea-Japan Symposium on Frontier Photoscience, Jun. 2015, Invited
  • 環境感応型蛍光性3-デアザ-2'-デオキシアデノシン誘導体の開発と塩基識別プローブへの応用
    鈴木梓、阿相達也、齋藤烈、齋藤義雄
    日本化学会第95春季年会, Mar. 2015, Not invited
  • Design of an environmentally sensitive fluorescent 3-deaza-2'-deoxyadenosine derivative: Detection of Thymine by probing the DNA minor groove
    A. Suzuki; T. Yanaba; I. Saito; Y. Saito
    The 41st International Symposium on Nucleic Acids Chemistry, Nov. 2014, Not invited
  • 環境感応型蛍光性3-デアザ-2'-デオキシアデノシン誘導体の開発とDNAプローブへの応用
    鈴木梓、簗場匠、阿相達也、齋藤烈、齋藤義雄
    2014年光化学討論会, Oct. 2014, Not invited
  • 環境感応型蛍光性8-アザ-7-デアザプリン-2,6-ジアミン誘導体の開発
    山坂勇喜、齋藤義雄
    平成26年度化学系学協会東北大会, Sep. 2014, Not invited
  • 新規蛍光性3-デアザ-2'-デオキシアデノシン誘導体の合成とDNAプローブの開発
    阿相達也、鈴木梓、齋藤義雄
    平成26年度化学系学協会東北大会, Sep. 2014, Not invited
  • ソルバトフルオロクロミックな性質を有するデアザプリンヌクレオシドの開発
    五十嵐将、鈴木梓、齋藤義雄
    平成26年度化学系学協会東北大会, Sep. 2014, Not invited
  • 新規蛍光性多環ヌクレオシドの開発
    白岩昭吾、鈴木梓、齋藤義雄
    平成26年度化学系学協会東北大会, Sep. 2014, Not invited
  • C7位に蛍光発色団を導入した新規8-アザ7-デアザプリンヌクレオシドの合成と光学特性
    山内拓史、齋藤義雄
    平成26年度化学系学協会東北大会, Sep. 2014, Not invited
  • Design and photophysical properties of environmentally sensitive fluorescent 8-aza-7-deaza -2'-deoxypurine nucleoside analogs
    A. Suzuki; I. Saito; Y. Saito
    XX International Round Table on Nucleosides, Nucleotides & Nucleic Acids, Aug. 2014, Not invited
  • Synthesis of an environmentally sensitive dual fluorescent 3-deaza -2'-deoxyadenosine derivative: distinction of thymine by probing microenvironmental changes in the DNA minor groove
    Y. Saito; A. Suzuki; T. Yanaba; I. Saito
    XX International Round Table on Nucleosides, Nucleotides & Nucleic Acids, Aug. 2014, Not invited
  • ナフタレン含有環境感応型蛍光3-デアザアデノシン誘導体の開発と一塩基識別プローブへの応用
    鈴木梓、齋藤烈、齋藤義雄
    第36回日本光医学・光生物学会, Jul. 2014, Not invited
  • 新規蛍光性8-アザ-7-デアザプリン-2,6-ジアミン誘導体の合成と光学特性
    山坂勇喜、鈴木梓、山内拓史、齋藤烈、齋藤義雄
    日本化学会第94春季年会, Mar. 2014, Not invited
  • 鈴木-宮浦カップリングでナフタレン誘導体を連結した8-アザ-7-デアザ-2'-デオキシプリンヌクレオシドの合成と光学特性
    鈴木梓、福間絵里香、齋藤烈、齋藤義雄
    日本化学会第94春季年会, Mar. 2014, Not invited
  • Design and photophysical properties of environmentally sensitive fluorescent (ESF) purine nucleosides
    Y. Saito
    The 9th Korea-Japan Symposium on Frontier Photoscience, Nov. 2013, Invited
  • Synthesis and photophysical properties of environmentally sensitive 8-aza-7-deazapurine nucleosides forming stable Watson-Crick base pairs
    A. Suzuki; Y. Yamasaka; I. Saito; Y. Saito
    The 40th International Symposium on Nucleic Acids Chemistry, Nov. 2013, Not invited
  • 環境感応型蛍光核酸の開発と遺伝子検出への応用
    齋藤義雄
    日本薬学会東北支部 第2回物理•分析系若手研究者セミナー, Nov. 2013, 日本薬学会東北支部, Invited
  • Environmentally sensitive fluorescent 8-aza-7-deaza-2'-deoxyadenosines that form a stable Watson-Crick base pair and their photophysical properties
    A. Suzuki; I. Saito; N. Nemoto; Y. Saito
    International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan, Sep. 2013, Not invited
  • Synthesis of solvatofluorochromic 7-arylethynylated 8-aza-7-deaza-2'-deoxyguanosine derivatives and their applications
    Y. Yamasaka; A. Suzuki; Y. Okada; I. Saito; Y. Saito
    International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan, Sep. 2013, Not invited
  • Development of polymeric nanoparticles for liver-specific ribavirin delivery
    T. Ishihara; N. Hirano; Y. Saito; M. Haruki; S. Uno; M. Makishima
    International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan, Sep. 2013, Not invited
  • Design and Synthesis of Environmentally Sensitive Fluorescent (ESF) Purine Nucleosides
    Y. Saito
    International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan, Sep. 2013, Invited
  • 環境感応型蛍光性8-アザ-7-デアザ-2'-デオキシアデノシン誘導体の開発とDNA蛍光プローブへの応用
    鈴木梓、齋藤烈、根本修克、齋藤義雄
    2013年光化学討論会, Sep. 2013, Not invited
  • 7位にアリールエチニル基を有する8-アザ-7-デアザ-2'-デオキシグアノシン誘導体を含むDNAプローブの合成と光学特性
    山坂勇喜、鈴木梓、岡田雄慈、齋藤烈、齋藤義雄
    2013年光化学討論会, Sep. 2013, Not invited
  • 8-アザ-7-デアザプリン骨格を有する環境感応型蛍光核酸塩基の開発と遺伝子検出への応用
    鈴木梓、齋藤烈、齋藤義雄
    第35回日本光医学・光生物学会, Jul. 2013, Not invited
  • ウラシルの5位にアントラセン骨格を有するpH蛍光センサーヌクレオシドの開発と応用
    横山祥太、宮本茂憲、齋藤烈、齋藤義雄
    日本化学会第93春季年会, Mar. 2013, Not invited
  • アリールエチニル基を有する新規蛍光性3-デアザ-2'-デオキシアデノシン誘導体の合成と光学特性
    簗場匠、長江亮幸、橋本優允子、齋藤烈、齋藤義雄
    日本化学会第93春季年会, Mar. 2013, Not invited
  • 新規蛍光性8-アザ-7-デアザプリンヌクレオシド誘導体の合成と光学と光学特性
    鈴木梓、岡田雄慈、本田かおり、齋藤烈、齋藤義雄
    日本化学会第93春季年会, Mar. 2013, Not invited
  • Efficient excess electron transfer through modified DNA using 2'-deoxyuridine derivatives
    M. Tanaka; K. Oguma; Y. Saito; I. Saito
    The 39th International Symposium on Nucleic Acids Chemistry, Nov. 2012, Not invited
  • Synthesis and photophysical properties of environmentally sensitive 7-deaza-2'-deoxyadenosine analogs
    A. Suzuki; I. Saito; N. Nemoto; Y. Saito
    The 39th International Symposium on Nucleic Acids Chemistry, Nov. 2012, Not invited
  • pH変化に敏感なアントラセン骨格を有する蛍光性ヌクレオシドの開発と応用
    鈴木梓、宮本茂憲、横山祥太、石原務、齋藤烈、根本修克、齋藤義雄
    2011年光化学討論会, Sep. 2012, Not invited
  • フェニルエチニル基を有するデオキシウリジン誘導体を電子メディエーターとする修飾DNA内の高効率過剰電子移動
    田仲真紀子、小熊一裕、齋藤義雄、齋藤烈
    2011年光化学討論会, Sep. 2012, Not invited
  • ピリジン骨格を有するpH蛍光センサーヌクレオシドの開発
    横山祥太、鈴木梓、宮本茂憲、齋藤烈、齋藤義雄
    平成24年度化学系学協会東北大会, Sep. 2012, Not invited
  • ナフタレンを含む新規蛍光性デアザアデノシン誘導体の合成と光特性
    簗場匠、石下真也、齋藤義雄
    平成24年度化学系学協会東北大会, Sep. 2012, Not invited
  • Synthesis and photophysical properties of novel push-pull-type fluorescent purine and 7-deazapurine 2'-deoxynucleosides
    A. Suzuki; I. Saito; N. Nemoto; Y. Saito
    XX International Round Table on Nucleosides, Nucleotides & Nucleic Acids, Aug. 2012, Not invited
  • Design and synthesis of pH-responsive fluorescent sensor nucleosides
    Y. Saito; S. Miyamoto; A. Suzuki; I. Saito
    XXIVth IUPAC Symposium on Photochemistry, Jul. 2012, Not invited
  • DNA二本鎖中に複数導入した修飾核酸塩基の光物性
    田仲真紀子、小熊一裕、小坂井亮太、齋藤義雄、齋藤烈
    日本化学会第92春季年会, Mar. 2012, Not invited
  • 8位にアリールエチニル基を有する2'-デオキシアデノシン誘導体の合成と光学特性
    岡田雄慈、高橋尚弥、桑原拓也、横山祥太、齋藤烈、齋藤義雄
    日本化学会第92春季年会, Mar. 2012, Not invited
  • デアザプリン骨格を有する新規蛍光ヌクレオシドの合成と光学特性
    鈴木梓、石下真也、簗場匠、工藤裕也、齋藤烈、根本修克、齋藤義雄
    日本化学会第92春季年会, Mar. 2012, Not invited
  • 【招待講演】新しい蛍光核酸の開発と遺伝子検出への応用
    有機合成化学協会東北支部福島地区講演会, Oct. 2011, Not invited
  • ソルバトクロミックな新規ピレン誘導体の合成と蛍光性グアノシンの光学特性
    齋藤義雄、石下真也、篠原雄太、鈴木梓、齋藤烈
    2011年光化学討論会, Sep. 2011, Not invited
  • 芳香族化合物を含むウリジン誘導体の合成とDNAへの複数導入による光物性の検討
    齋藤義雄、小熊一裕、田仲真紀子、齋藤烈
    2011年光化学討論会, Sep. 2011, Not invited
  • ナフタレン骨格を有する新規蛍光性アデノシン誘導体の合成と光特性
    岡田雄慈、高橋尚弥、齋藤烈、齋藤義雄
    平成23年度化学系学協会東北大会, Sep. 2011, Not invited
  • 環境感応型蛍光プローブとなる新規核酸塩基誘導体の開発とその応用
    田仲真紀子、小熊一裕、小坂井亮太、久下沼賢志、齋藤義雄、齋藤烈
    第33回日本光医学・光生物学会, Jul. 2011, Not invited
  • 芳香族化合物をエチニルリンカーで連結した核酸塩基誘導体の光物性
    田仲真紀子、小熊一裕、齋藤義雄、齋藤烈
    日本化学会第91春季年会, Mar. 2011, Not invited
  • C8位にアリールブタジエニル基を含む新規2'-デオキシグアノシン誘導体の合成と光化学的性質
    齋藤義雄、幸田真基夫、篠原雄太、齋藤烈
    日本化学会第91春季年会, Mar. 2011, Not invited
  • 1,6および2,7置換ピレンを含む2'-デオキシグアノシン誘導体の合成と光化学的性質
    齋藤義雄、鈴木梓、石下真也、齋藤烈
    日本化学会第91春季年会, Mar. 2011, Not invited
  • Design of ends free and self-quenched molecular beacon for SNPs genotyping
    Y. Saito; A. Matsumoto; I. Saito
    The International Chemical Congress of Pacific Basin Societies 2010 (PACIFICHEM), Dec. 2010, Not invited
  • Synthesis and photophysical properties of novel push-pull-type solvatochromic 2'-deoxyguanosine derivatives
    Y. Saito; A. Suzuki; I. Saito
    The International Chemical Congress of Pacific Basin Societies 2010 (PACIFICHEM), Dec. 2010, Not invited
  • Synthesis of pyrene labeled push-pull-type 2'-deoxyguanosine derivatives and its photophysical properties
    Y. Saito; A. Suzuki; S. Ishioroshi; K. Oguma; K. Kugenuma; M. Koda; R. Kozakai; S. Miyamoto; I. Saito
    The 37th International Symposium on Nucleic Acids Chemistry 2010, Nov. 2010, Not invited
  • Push-Pull型ピレン含有2'―デオキシグアノシン誘導体の合成と光学特性
    齋藤義雄、鈴木梓、今井和俊、根本修克、齋藤烈
    2010年光化学討論会, Sep. 2010, Not invited
  • アシル置換ビニルピレン含有2'-デオキシグアノシンの合成と蛍光特性
    石下真也、齋藤義雄、齋藤烈
    平成22年度化学系学協会東北大会, Sep. 2010, Not invited
  • 8位で共役ジエンで連結した置換2'-デオキシグアノシン誘導体の合成と光化学的性質
    幸田真基夫、齋藤義雄、齋藤烈
    平成22年度化学系学協会東北大会, Sep. 2010, Not invited
  • 5位に置換アリールエチニル基を有する新規ウリジン誘導体の合成と応用
    小熊一裕、田仲真紀子、齋藤義雄、齋藤烈
    平成22年度化学系学協会東北大会, Sep. 2010, Not invited
  • 8位に置換アリールエチニル基を有する2'-デオキシグアノシン誘導体の合成とDNAへの導入
    久下沼賢志、齋藤義雄、齋藤烈
    平成22年度化学系学協会東北大会, Sep. 2010, Not invited
  • pHに鋭敏な蛍光核酸塩基の開発
    宮本茂憲、齋藤義雄、齋藤烈
    平成22年度化学系学協会東北大会, Sep. 2010, Not invited
  • 新規2-アリールエチニル置換2'-デオキシグアノシン誘導体の合成
    小坂井亮太、齋藤義雄、齋藤烈
    平成22年度化学系学協会東北大会, Sep. 2010, Not invited
  • 新しい機能性核酸の合成と遺伝子検出への応用
    第5回相模ケイ素材料フォーラム, Aug. 2010, 公益財団法人相模中央化学研究所, Not invited
  • 【第31回奨励賞受賞記念講演】遺伝子診断のための蛍光DNAプローブの開発
    第32回日本光医学・光生物学会, Jul. 2010, Not invited
  • 極性環境変化に敏感な蛍光核酸塩基を用いた遺伝子検出プローブ
    松本桂彦、森井孝、齋藤義雄、齋藤烈
    第32回日本光医学・光生物学会, Jul. 2010, Not invited
  • Design of ends free and quencher free molecular beacons
    Y. Saito; Y. Shinohara; K. Matsumoto; I. Saito
    XXIIIrd IUPAC Symposium on Photochemistry, Jul. 2010, Not invited
  • キノリン環を含む核酸塩基の合成
    齋藤義雄、小坂井亮太、松本桂彦、篠原雄太、高橋尚弥、齋藤烈
    日本化学会第90春季年会, Mar. 2010, Not invited
  • 8位に置換アリールエチニル基を有する2'―デオキシグアノシン誘導体の合成
    齋藤義雄、久下沼賢志、幸田真基夫、篠原雄太、松本桂彦、鈴木梓、齋藤烈
    日本化学会第90春季年会, Mar. 2010, Not invited
  • 5位に置換アリールエチニル基を有するウリジン誘導体の合成と光化学的性質
    齋藤義雄、小熊一裕、松本桂彦、竹内辰樹、齋藤烈
    日本化学会第90春季年会, Mar. 2010, Not invited
  • 溶媒極性で蛍光が変化する2'-デオキシグアノシン誘導体の合成と応用
    齋藤義雄、篠原雄太、松本桂彦、齋藤烈
    日本化学会第90春季年会, Mar. 2010, Not invited
  • Photo-switching of vinylpyrene-substituted 2'-deoxyguanosine and its application
    Y. Saito; Y. Takeuchi; K. Matsumoto; N. Takahashi; A. Suzuki; I. Saito
    The 6th International Symposium on Nucleic Acids Chemistry (36th Symposium on Nucleic Acids Chemistry), Sep. 2009, Not invited
  • Design of extremely facile 3'- and 5'- ends free molecular beacons using C8 alkylamino substituted 2'-deoxyguanosine
    K. Matsumoto; Y. Shinohara; S. S. Bag; Y. Takeuchi; T. Morii; Y. Saito; I. Saito
    The 6th International Symposium on Nucleic Acids Chemistry (36th Symposium on Nucleic Acids Chemistry), Sep. 2009, Not invited
  • 溶媒極性に敏感な新規蛍光性核酸塩基の合成とその応用
    高橋尚弥、篠原雄太、齋藤烈
    平成21年度化学系学協会東北大会, Sep. 2009, Not invited
  • ピレン骨格を有する新規蛍光プローブの開発とDNA検出への応用
    鈴木梓、今井和俊、根本修克、齋藤烈
    平成21年度化学系学協会東北大会, Sep. 2009, Not invited
  • 新しい遺伝子検出プローブの開発
    平成21年度化学系学協会東北大会【特別企画:有機化学コロキウム】, Sep. 2009, Not invited
  • 新しいSolvofluorochromicなプリン核酸塩基のデザインと応用
    高橋尚弥、松本桂彦、篠原雄太、竹内辰樹、齋藤烈
    2009年光化学討論会, Sep. 2009, Not invited
  • DNA検出のためのアントラセン、ピレン骨格を有するTwinプローブの開発
    鈴木梓、篠原雄太、石下真也、今井和俊、根本修克、齋藤烈
    2009年光化学討論会, Sep. 2009, Not invited
  • 両末端フリーの自己消光型モレキュラービーコンの開発
    篠原雄太、松本桂彦、沼尻恭子、齋藤烈
    2009年光化学討論会, Sep. 2009, Not invited
  • 遺伝子検出の為の画期的なモレキュラービーコンの開発
    松本桂彦、篠原雄太、竹内辰樹、齋藤烈、森井孝
    第24回生体機能関連化学シンポジウム,第12回バイオテクノロジー部会シンポジウム, Sep. 2009, Not invited
  • 遺伝子診断のための画期的なモレキュラービーコンの開発
    齋藤烈
    第31回日本光医学・光生物学会, Jul. 2009, Not invited
  • C8位にリンカーをもつ新規グアノシン誘導体の応用
    松本桂彦、篠原雄太、沼尻恭子、水野絵梨香、笠原竜、佐藤直樹、藤井美里、齋藤烈
    日本化学会第89春季年会, Mar. 2009, Not invited
  • ビニルピレン置換グアニン塩基を用いる蛍光スイッチの開発
    竹内辰樹、松本桂彦、高橋尚弥、齋藤烈
    日本化学会第89春季年会, Mar. 2009, Not invited
  • アントラセン骨格を有するTwinプローブの開発と遺伝子検出への応用
    篠原雄太、鈴木梓、石下真也、齋藤烈
    日本化学会第89春季年会, Mar. 2009, Not invited
  • 蛍光消光型プローブを用いたモレキュラービーコンの開発
    篠原雄太、竹内辰樹、松本桂彦、齋藤烈
    平成20年度化学系学協会東北大会, Oct. 2008, Not invited
  • 光応答性ヌクレオシドの合成と応用
    竹内辰樹、松本桂彦、齋藤烈
    平成20年度化学系学協会東北大会, Oct. 2008, Not invited
  • ポストDNA修飾可能な2’-デオキシグアノシン誘導体の合成と応用
    松本桂彦、藤井美里、齋藤烈
    平成20年度化学系学協会東北大会, Oct. 2008, Not invited
  • 芳香環を含む新規ヌクレオシドの合成とDNA鎖への導入
    水野絵梨香、沼尻恭子、齋藤烈
    平成20年度化学系学協会東北大会, Oct. 2008, Not invited
  • クエンチャーフリーモレキュラービーコンの開発とDNA検出
    沼尻恭子、松本桂彦、水野絵梨香、齋藤烈
    平成20年度化学系学協会東北大会, Oct. 2008, Not invited
  • 平成20年度化学系学協会東北大会
    平成20年度化学系学協会東北大会, Oct. 2008, Not invited
  • Fluorometric sensing of the B–Z DNA transition of DNA containing C8-alkylamino substituted 2'-deoxyguanosine
    K. Matsumoto; S. S. Bag; A. Misawa; I. Saito
    Joint Symposium of the 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry, Sep. 2008, Not invited
  • Design of an ultimate quencher free molecular beacon containing pyrrolocytidine-guanine base pair
    Y. Shinohara; S. S. Bag; Y. Takeuchi; K. Matsumoto; I. Saito
    Joint Symposium of the 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry, Sep. 2008, Not invited
  • Design of an efficient self-quenched molecular beacon for SNPs genotyping
    K. Numajiri; S. S. Bag; E. Mizuno; I. Saito
    Joint Symposium of the 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry, Sep. 2008, Not invited
  • Design of Practically Important Fluorescent Molecules for SNP Genotyping –Ends Free and Quencher Free Molecular Beacons-
    Y. Shinohara; S. S. Bag; Y. Takeuchi; E. Mizuno; K. Numajiri; K. Matsumoto; I. Saito
    International Symposium on Molecular Recognition of DNA: Biological Application, Sep. 2008, Not invited
  • フォトクロミック核酸塩基のデザインと合成
    松本桂彦、BAG Subhendu Sekhar、小舘知史、齋藤烈
    2008年光化学討論会, Sep. 2008, Not invited
  • ピレン含有pyrrolocytidine誘導体を用いたクエンチャーフリーモレキュラービーコンの開発
    竹内辰樹、篠原雄太、松本桂彦、齋藤烈
    2008年光化学討論会, Sep. 2008, Not invited
  • Design of G-quenched molecular beacons for DNA detection
    Y. Saito; E. Mizuno; K. Numajiri; S.S. Bag; I. Saito
    XXIInd IUPAC Symposium on Photochemistry, Jul. 2008, Not invited
  • Solvent dependencies in the fluorescence quantum yield of some aromatic carbonyl derivatives as fluorescence probe
    S. Kodate; H. Wada; S. Yoshimoto; I. Suzuka; S.S. Bag; Y. Saito; I. Saito
    XXIInd IUPAC Symposium on Photochemistry, Jul. 2008, Not invited
  • 遺伝子診断のためのクエンチャー分子を用いないモレキュラービーコンの開発
    水野絵梨香、沼尻恭子、BAG Subhendu Sekhar、齋藤烈
    第30回日本光医学・光生物学会, Jul. 2008, Not invited
  • 蛍光プローブを用いたDNA塩基配列の解析
    第4回東北地区活性化若手セミナー, Mar. 2008, Not invited
  • グアニンによる蛍光消光を利用したG認識プローブの開発
    篠原雄太、竹内辰樹、齋藤烈
    日本化学会第88春季年会, Mar. 2008, Not invited
  • クエンチャーフリーモレキュラービーコンの開発
    水野絵梨香、沼尻恭子、BAG Subhendu Sekhar、鈴鹿敢、齋藤烈
    日本化学会第88春季年会, Mar. 2008, Not invited
  • C8位を置換した2'-デオキシグアノシン誘導体の合成と応用
    松本桂彦、三澤祥大、鈴鹿敢、齋藤烈
    日本化学会第88春季年会, Mar. 2008, Not invited
  • Synthesis of C8-alkylamino substituted 2'-deoxyguanosine
    K. Matsumoto; S. S. Bag; S. Ogasawara; I. Suzuka; I. Saito
    第5回国際核酸化学シンポジウム, Nov. 2007, Not invited
  • Design of dual-labeled oligonucleotide probes for SNPs genotyping
    S. S. Bag; S. Kodate; I. Suzuka; I. Saito
    第5回国際核酸化学シンポジウム, Nov. 2007, Not invited
  • C8位にアルキルアミノ基を有する2'-デオキシグアノシン誘導体の合成
    松本桂彦、鈴鹿敢、齋藤烈
    平成19年度化学系学協会東北大会, Sep. 2007, Not invited
  • 蛍光消光分子を必要としないモレキュラービーコンの開発
    水野絵梨香、鈴鹿敢、齋藤烈
    平成19年度化学系学協会東北大会, Sep. 2007, Not invited
  • ドナー・アクセプター置換基をもつピレン化合物の二重蛍光ダイナミクス
    小舘知史、和田晴光、岡本晃充、田井中一貴、BAG Subhendu Sekhar、鈴鹿敢、齋藤烈
    2007年光化学討論会, Sep. 2007, Not invited
  • ペリレンカルボニル誘導体の蛍光寿命と低温スペクトル‐ペリレンカルボニル誘導体との比較‐
    和田晴光、小舘知史、鈴鹿敢、BAG Subhendu Sekhar、齋藤烈
    2007年光化学討論会, Sep. 2007, Not invited
  • クエンチャーを必要としないモレキュラービーコンの開発
    水野絵梨香、BAG Subhendu Sekhar、鈴鹿敢、齋藤烈
    2007年光化学討論会, Sep. 2007, Not invited
  • FRETを用いた塩基識別型蛍光性核酸塩基の開発
    齋藤義雄、松本桂彦、水野絵梨香、小舘知史、鈴鹿敢、齋藤烈
    第29回日本光医学・光生物学会, Jul. 2007, Not invited
  • 第29回日本光医学・光生物学会
    第29回日本光医学・光生物学会, Jul. 2007, Not invited
  • 塩基識別型蛍光性核酸塩基(BDF)の開発: アントラセンで蛍光標識された2'―デオキシヌクレオシドによる塩基識別
    BAG Subhendu Sekhar、齋藤義雄、花輪和夫、小舘知史、鈴鹿敢、齋藤烈
    日本化学会第87春季年会, Mar. 2007, Not invited
  • FRETを利用した塩基識別型蛍光性核酸塩基(BDF)の開発
    齋藤義雄、花輪和夫、日下部雄一、松本桂彦、小舘知史、鈴鹿敢、齋藤烈
    日本化学会第87春季年会, Mar. 2007, Not invited
  • 新規ペリレン修飾塩基識別型蛍光性核酸塩基(BDF)プローブの合成とその性質
    林圭吾、永井千晴、水野絵梨香、小舘知史、鈴鹿敢、齋藤義雄、齋藤烈
    日本化学会第87春季年会, Mar. 2007, Not invited
  • ペリレンカルボニル誘導体の発光電子状態の特性
    和田晴光、小舘知史、鈴鹿敢、BAG Subhendu Sekhar、齋藤義雄、齋藤烈
    日本化学会第87春季年会, Mar. 2007, Not invited
  • Synthesis of pyrene-labeled base-discriminating fluorescent (BDF) nucleoside and its fluorescence properties
    S. S. Bag; Y. Saito; K. Hanawa; K. Hayashi; S. Kodate; I. Suzuka; I. Saito
    第33回核酸化学シンポジウム, Nov. 2006, Not invited
  • Synthesis and properties of acridone-labeled base-discriminating fluorescent (BDF) nucleosides
    Y. Saito; K. Hanawa; S. S. Bag; K. Motegi; I. Saito
    第33回核酸化学シンポジウム, Nov. 2006, Not invited
  • Luminescence properties of dual fluorescent pyrene derivatives used as DNA probe molecule
    S. Kodate; H. Wada; I. Suzuka; A. Okamoto; K. Tainaka; Y. Saito; I. Saito
    第33回核酸化学シンポジウム, Nov. 2006, Not invited
  • 長波長で発光する塩基識別型蛍光性核酸塩基(FRET-BDFプローブ)の開発
    齋藤義雄、永井千晴、日下部雄一、小舘知史、鈴鹿敢、齋藤烈
    2006年光化学討論会, Sep. 2006, Not invited
  • ピレン系DNA蛍光プローブ分子の二重蛍光メカニズムに関する新しい解釈
    小舘知史、和田晴光、鈴鹿敢、岡本晃充、田井中一貴、齋藤義雄、齋藤烈
    2006年光化学討論会, Sep. 2006, Not invited
  • ペリレンカルボニル誘導体の量子収量の溶媒効果と発光電子状態に関する検討
    和田晴光、小舘知史、鈴鹿敢、Subhendu S. Bag、齋藤義雄、齋藤烈
    2006年光化学討論, Sep. 2006, Not invited
  • 次世代DNAチップの開発
    齋藤義雄
    科学技術振興機構SORSTシンポジウム ゲノム化学の最先端―医学・分子生物学への応用と展開, Sep. 2006, Not invited
  • 蛍光ラベリングがいらないDNAチップの開発
    齋藤烈、齋藤義雄
    国際バイオエキスポ ―バイオアカデミックフォーラム―, May 2006, Not invited
  • 塩基識別型蛍光性核酸塩基(BDF): アクリドンで蛍光標識された2'-デオキシヌクレオシド誘導体による塩基識別
    齋藤義雄、花輪和夫、林圭吾、BAG S.S.、石田智哉、川崎尚美、齋藤烈
    日本化学会第86春季年会, Mar. 2006, Not invited
  • 新規リンカーを有する塩基識別型蛍光性核酸塩基によるチミン塩基の識別
    齋藤義雄、茂木かおり、齋藤烈
    日本化学会第86春季年会, Mar. 2006, Not invited
  • 日本化学会第86春季年会
    日本化学会第86春季年会, Mar. 2006, Not invited
  • FRETを利用した塩基識別型蛍光性核酸塩基の開発
    齋藤義雄、岡本晃充、齋藤烈
    2005年光化学討論会, Sep. 2005, Not invited
  • ピレンカルボニル誘導体の励起状態の帰属と蛍光消光過程に関する再検討
    小舘知史、齋藤義雄、竹内健太、鈴鹿敢、齋藤烈
    2005年光化学討論会, Sep. 2005, Not invited
  • Design of highly selective fluorescent nucleobases for SNP typing: Base-discriminating fluorescent (BDF) probe
    I. Saito; Y. Saito; A. Okamoto; T. Ichiba; K. Kanatani; K. Tainaka
    Chemistry of Nucleic Acid components, XIIIth Symposium, Sep. 2005, Not invited
  • FRETを利用した塩基識別型蛍光性核酸塩基(BDF塩基)の開発
    齋藤義雄、齋藤烈
    第27回日本光医学・光生物学会, Aug. 2005, Not invited
  • 塩基識別型蛍光性核酸塩基(BDF):蛍光標識された2'-デオキシアデノシン誘導体による塩基識別
    齋藤義雄、花輪和夫、茂木かおり、岡本晃充、齋藤烈
    日本化学会第85春季年会, Mar. 2005, Not invited
  • 塩基識別型蛍光性核酸塩基(BDF)-アデノシン識別プローブの開発-
    齋藤義雄、遠藤文敬、岡本晃充、齋藤烈
    日本化学会第85春季年会, Mar. 2005, Not invited
  • 塩基識別型蛍光性核酸塩基–蛍光消光によるチミン塩基の識別-
    齋藤義雄、遠藤文敬、茂木かおり、花輪和夫、岡本晃充、齋藤烈
    2004年光化学討論会, Nov. 2004, Not invited
  • 塩基識別型蛍光性核酸塩基(BDF)のデザインとSNPタイピング
    Y. Saito; K. Kanatani; Y. Ochi; A. Okamoto; I. Saito
    第31回核酸化学シンポジウム, Nov. 2004, Not invited
  • Base-discriminating fluorescent (BDF) nucleoside: distinction of thymine by fluorescence quenching
    Y. Saito; Y. Miyauchi; A. Okamoto; I. Saito
    20th IUPAC Symposium on Photochemistry, Jul. 2004, Not invited
  • Design of Base-Discriminating Fluorescent Nucleoside for SNP Typing
    I. Saito; K. Kanatani; Y. Saito; A. Okamoto
    14th International Congress on Photobiology, Jun. 2004, Not invited
  • 新規光連結性核酸の合成と性質
    宮内陽平、齋藤義雄、藤本健造、齋藤烈
    日本化学会第84春季年会, Mar. 2004, Not invited
  • 塩基識別型蛍光性核酸塩基–デアザアデノシン型プローブによるピリミジン塩基の認識-
    齋藤義雄、金谷啓一郎、岡本晃充、齋藤烈
    日本化学会第84春季年会, Mar. 2004, Not invited
  • アデノシン8位に蛍光分子を導入した新規修飾核酸塩基の合成と評価
    齋藤義雄、尾本賢治、岡本晃充、齋藤烈
    日本化学会第84春季年会, Mar. 2004, Not invited
  • 塩基識別型蛍光性核酸塩基–デアザアデノシン型プローブによるピリミジン塩基の認識-
    齋藤義雄、金谷啓一郎、岡本晃充、齋藤烈
    2003年光化学討論会, Nov. 2003, Not invited
  • Conception de nucléosides non-classiques incluant des 1,2,3-triazolo-carbanucléosides ciblant le virus de l’hépatite C (VHC) dans u système réplicon
    Y. Saito; N. Joubert; V. Aucagne; V. Escuret; D. Durantel; F. Zoulim; R. F. Schinazi; L. A. Agrofoglio
    16ème colloque biotechnocentre, Nov. 2003, Not invited
  • Synthesis of benzotrithiole oxide derivatives and their DNA-cleaving activity
    Y. Saito; T. Bando; H. Sugiyama; I. Saito
    39th IUPAC Congress and 86th Conference of The Canadian Society for Chemistry, Aug. 2003, Not invited
  • HPLC and mass spectrometry analysis of the enzymatic hydrolysis of anti-HIV Pronucleotide diastereomers
    N. Mesplet; Y. Saito; Ph. Morin; L. A. Agrofoglio
    The 2nd IAS Conference on HIV Pathogenesis and Treatment (IAS 2003), Jul. 2003, Not invited
  • benzotrithiole oxideによるDNA切断と応用
    齋藤義雄、板東俊和、杉山弘、齋藤烈
    日本化学会第83春季年会, Mar. 2003, Not invited
  • Separation of diastereomers of anti-HIV amidate pro-drugs by chiral liquid chromatography
    L. A. Agrofoglio; N. Mesplet; Y. Saito; P. Morin
    15th International Conference on Antiviral Research (ICAR), Mar. 2002, Not invited
  • Synthesis of isosteric phosphonate analogs of cyclopentyl carbocyclic 3'-deoxyribonucleosides
    Y. Saito; B. Legeret; J. Blu; L. A. Agrofoglio
    37th International Meeting on Medicinal Chemistry, Jul. 2001, Not invited
  • Evaluation of volatile elutions for capillary electrophoresis of the active metabolite of anti-HIV didanosine
    T. T. Tran; Y. Saito; P. Morin; L. A. Agrofoglio
    37th International Meeting on Medicinal Chemistry, Jul. 2001, Not invited
  • Efficient synthesis of D-[1'-13C] ribonucleosides for incorporation into oligo-RNA
    Y. Saito; A. Nyilas; L. A. Agrofoglio
    XIV International Round Table-Nucleoside, Nucleotide and Their Biological Applications, Sep. 2000, Not invited
  • Synthesis and anti-HIV activity of unusual nucleoside oxanosine derivatives
    齋藤義雄、チャイチャローンポングチャンヤー、大野修、市川英子、山村庄亮、加藤國基、中村真理子、大野典也、梅澤一夫
    第26回核酸化学シンポジウム, Sep. 1999, Not invited
  • 異常ヌクレオシド・オキザノシンの誘導体合成と生物活性
    齋藤義雄、大野修、市川英子、山村庄亮、加藤國基、梅澤一夫
    日本薬学会第119年会, Mar. 1999, Not invited

Affiliated academic society

  • Dec. 2008 - Present
    有機合成化学協会
  • Oct. 2004 - Present
    日本光医学・光生物学会
  • Oct. 2004 - Present
    光化学協会
  • Nov. 2002 - Present
    日本化学会
  • Dec. 1996 - Present
    日本薬学会

Research Themes

  • Development of novel environmentally sensitive fluorescent PNA probes
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2019 - 31 Mar. 2022
    SAITO Yoshio
  • Development of dual-fluorescent ODN probes for SNPs typing
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2016 - 31 Mar. 2019
    Saito Yoshio
  • Development of pH-responsive fluorescent nucleosides for SNPs detection
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2013 - 31 Mar. 2016
    SAITO Yoshio
  • Design of Environmentally Sensitive Fluorescent Nucleosides and Their Application to Innovative Fluorescence Probe for Gene Analysis
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2011 - 31 Mar. 2014
    SAITO Isao; SAITO Yoshio

Industrial Property Rights

  • 特願2014-107161, ウラシルヌクレオシド誘導体、ウラシルヌクレオチド誘導体及びポリヌクレオチド誘導体ならびにそれらを含むプローブ
    齋藤義雄、横山祥太、鈴木梓
  • 特願2014-26733, 3-デアザプリンヌクレオシド誘導体、3-デアザプリンヌクレオチド誘導体及びポリヌクレオチド誘導体
    齋藤義雄、簗場匠、鈴木梓
  • 特願2016-022811, 化合物、プローブ、縮合物及びシトシンの検出方法
    齋藤義雄、白岩昭吾
  • 特願2015-15525, 8-アザ-3,7-ジデアザアデニンヌクレオシド誘導体、8-アザ-3,7-ジデアザアデニンヌクレオチド誘導体及びポリヌクレオチド誘導体ならびにプローブ
    齋藤義雄、鈴木梓、齋藤未生
  • 特願2008-225347, ステムループ構造を有する蛍光プローブ
    齋藤烈、松本桂彦
  • 特願2012-021547, 蛍光DNAプローブに応用可能な新規蛍光性デアザプリンヌクレオシド誘導体
    齋藤義雄、齋藤烈、鈴木梓、石下真也
  • 特願2009-188664, C8位置換プリン塩基誘導体及びそれを利用した蛍光プローブ
    齋藤烈、高橋尚弥
  • 特開2008-162916, 特願2006-352017, 水素結合性置換基を有する8―置換グアノシン誘導体及びそれを含むオリゴヌクレオチド
  • 特開2007-31388, 特願2005-219708, ヌクレオチド誘導体及びその利用(FRET)
  • 特開2007-31389, 特願2005-219709, ヌクレオチド誘導体及びその利用(アントラセン)
  • 特開2006-76905, 特願2004-260749, 光反応性核酸及び可逆的核酸光連結又は開裂方法
  • PCT/JP2005/004703, ヌクレオチド誘導体とDNAマイクロアレイ