Life sciences, Tumor biology

Evaluation of the Mechanisms Involved in the Development of Bladder Toxicity following Exposure to Occupational Bladder Cancer Causative Chemicals Using DNA Adductome Analysis
Shugo Suzuki; Min Gi; Masami Komiya; Asuka Obikane; Arpamas Vachiraarunwong; Masaki Fujioka; Anna Kakehashi; Yukari Totsuka; Hideki Wanibuchi
Biomolecules, Dec. 2023, Refereed

Cytotoxic Homo- and Hetero-Dimers of o-toluidine, o-anisidine, and Aniline Formed by In Vitro Metabolism.
Takuma Kobayashi; Shinji Kishimoto; Shogo Watanabe; Yasukiyo Yoshioka; Takeshi Toyoda; Kumiko Ogawa; Kenji Watanabe; Yukari Totsuka; Keiji Wakabayashi; Noriyuki Miyoshi
Chemical research in toxicology, Sep. 2022, Refereed

Induction of DNA Damage in Mouse Colorectum by Administration of Colibactin-producing Escherichia coli, Isolated from a Patient With Colorectal Cancer
TAKUMI NARITA; YUTA TSUNEMATSU; NORIYUKI MIYOSHI; MASAMI KOMIYA; TAKAHIRO HAMOYA; GEN FUJII; YUKO YOSHIKAWA; MICHIO SATO; MASANOBU KAWANISHI; HARUHIKO SUGIMURA; YUJI IWASHITA; YUKARI TOTSUKA; MASARU TERASAKI; KENJI WATANABE; KEIJI WAKABAYASHI; MICHIHIRO MUTOH
In Vivo, 2022, Refereed

Complex Modulating Effects of Dietary Calcium Intake on Obese Mice.
Takahashi M; Hamoya T; Narita T; Fujii G; Totsuka Y; Hagio M; Tashiro K; Komiya M; Mutoh M
In Vivo, Jul. 2021, Refereed

o-Anisidine Dimer, 2-Methoxy-N4-(2-methoxyphenyl) Benzene-1,4-diamine, in Rat Urine Associated with Urinary bladder Carcinogenesis.
Takuma Kobayashi; Takeshi Toyoda; Yuya Tajima; Shinji Kishimoto; Yuta Tsunematsu; Michio Sato; Kohei Matsushita; Takanori Yamada; Yuko Shimamura; Shuichi Masuda; Masako Ochiai; Kumiko Ogawa; Kenji Watanabe; Takeji Takamura-Enya; Yukari Totsuka; Keiji Wakabayashi; Noriyuki Miyoshi
Chemical research in toxicology, Mar. 2021, Refereed

U.S.-Japan cooperative medical sciences program: 22nd International Conference on Emerging Infectious Diseases in the Pacific Rim.
Kristina T Lu; Takuya Yamamoto; David McDonald; Wei Li; Marissa Tan; Meng Ling Moi; Eun-Chung Park; Kumiko Yoshimatsu; Marie Ricciardone; Allan Hildesheim; Yukari Totsuka; Asuka Nanbo; Opass Putcharoen; Gompol Suwanpimolkul; Watsamon Jantarabenjakul; Leilani Paitoonpong; F Gray Handley; K Gayle Bernabe; Masahiko Noda; Miwa Sonoda; Patrick Brennan; Diane E Griffin; Ichiro Kurane
Virology, Mar. 2021, Refereed

Establishment of Novel Genotoxicity Assay System Using Murine Normal Epithelial Tissue-Derived Organoids.
Masami Komiya; Rikako Ishigamori; Mie Naruse; Masako Ochiai; Noriyuki Miyoshi; Toshio Imai; Yukari Totsuka
Frontiers in genetics, 2021, Refereed
Corresponding

New horizons of DNA adductome for exploring environmental causes of cancer.
Yukari Totsuka; Masatoshi Watanabe; Yingsong Lin
Cancer science, Jan. 2021
Lead

Correction to A Novel o-Toluidine Metabolite in Rat Urine Associated with Urinary Bladder Carcinogenesis.
Yuya Tajima; Takeshi Toyoda; Yuichiro Hirayama; Kohei Matsushita; Takanori Yamada; Kumiko Ogawa; Kenji Watanabe; Takeji Takamura-Enya; Yukari Totsuka; Keiji Wakabayashi; Noriyuki Miyoshi
Chemical research in toxicology, Dec. 2020, Refereed

Novel o-Toluidine Metabolite in Rat Urine Associated with Urinary Bladder Carcinogenesis.
Yuya Tajima; Takeshi Toyoda; Yuichiro Hirayama; Kohei Matsushita; Takanori Yamada; Kumiko Ogawa; Kenji Watanabe; Takeji Takamura-Enya; Yukari Totsuka; Keiji Wakabayashi; Noriyuki Miyoshi
Chemical research in toxicology, May 2020, Refereed, Not invited

がん患者ゲノムDNAにおける化学損傷のバイオマーカー、DNA付加体の多様性(Diversity of DNA adducts as a biomarker for chemical damages on genome DNA of cancer patients)
岩下 雄二; 大西 一平; 大塚 駿介; 松島 芳隆; 戸塚 ゆ加里; 鈴木 潮人; 森 弘樹; 小澤 享史; 谷岡 書彦; 椙村 春彦
日本病理学会会誌, Mar. 2020

がん患者ゲノムDNAにおける化学損傷のバイオマーカー、DNA付加体の多様性(Diversity of DNA adducts as a biomarker for chemical damages on genome DNA of cancer patients)
岩下 雄二; 大西 一平; 大塚 駿介; 松島 芳隆; 戸塚 ゆ加里; 鈴木 潮人; 森 弘樹; 小澤 享史; 谷岡 書彦; 椙村 春彦
日本病理学会会誌, Mar. 2020

Biological significance of aminophenyl-β-carboline derivatives formed from co-mutagenic action of β-carbolines and aniline and o-toluidine and its effect on tumorigenesis in humans: A review.
Totsuka Y; Wakabayashi K
Mutat Res., Mar. 2020, Refereed
Lead

Genotoxicity of micro- and nano-particles of kaolin in human primary dermal keratinocytes and fibroblasts.
Masanobu Kawanishi; Reimi Yoneda; Yukari Totsuka; Takashi Yagi
Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2020, Refereed

Comprehensive analysis of DNA adducts (DNA adductome analysis) in the liver of rats treated with 1,4-dioxane.
Yukari Totsuka; Yuya Maesako; Hanako Ono; Momoko Nagai; Mamoru Kato; Min Gi; Hideki Wanibuchi; Shoji Fukushima; Kazuhiro Shiizaki; Hitoshi Nakagama
Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2020, Refereed, Not invited
Corresponding

High information content assays for genetic toxicology testing: A report of the International Workshops on Genotoxicity Testing (IWGT).
Stephen D Dertinger; Yukari Totsuka; Jason H Bielas; Ann T Doherty; Jos Kleinjans; Masamitsu Honma; Francesco Marchetti; Maik J Schuler; Veronique Thybaud; Paul White; Carole L Yauk
Mutation research, Nov. 2019, Refereed

Quantitative analysis of mutagenicity and carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in F344 gpt delta transgenic rats
Min Gi; Masaki Fujioka; Yukari Totsuka; Michiharu Matsumoto; Kenichi Masumura; Anna Kakehashi; Takashi Yamaguchi; Shoji Fukushima; Hideki Wanibuchi
Mutagenesis, Sep. 2019, Refereed, Not invited

DNA Adductome Analysis Identifies N-Nitrosopiperidine Involved in the Etiology of Esophageal Cancer in Cixian, China
Totsuka Y; Lin Y; He Y; Ishino K; Sato H; Kato M; Nagai M; Elzawahry A; Totoki Y; Nakamura H; Hosoda F; Shibata T; Matsuda T; Matsushima Y; Song G; Meng F; Li D; Liu J; Qiao Y; Wei W; Inoue M; Kikuchi S; Nakagama H; Shan B
Chemical Research in Toxicology, Aug. 2019, Refereed, Not invited

γ-H2AX formation in the urinary bladder of rats treated with two norharman derivatives obtained from o-toluidine and aniline
T. Toyoda; Y. Totsuka; K. Matsushita; T. Morikawa; N. Miyoshi; K. Wakabayashi; K. Ogawa
Journal of Applied Toxicology, Apr. 2018, Refereed, Not invited

Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.
Emi Fukai; Haruna Sato; Masatoshi Watanabe; Dai Nakae; Yukari Totsuka
Cancer science, Apr. 2018, Refereed, Not invited
Corresponding

Influence of GSH S-transferase on the mutagenicity induced by dichloromethane and 1,2-dichloropropane.
Nozomi Akiba; Kazuhiro Shiizaki; Yoshitaka Matsushima; Osamu Endo; Kazuho Inaba; Yukari Totsuka
Mutagenesis, Jul. 2017, Refereed, Not invited
Corresponding

Esophageal cancer in high-risk areas of China: research progress and challenges.
Yingsong Lin; Yukari Totsuka; Baoen Shan; Chaochen Wang; Wenqiang Wei; Youlin Qiao; Shogo Kikuchi; Manami Inoue; Hideo Tanaka; Yutong He
Annals of epidemiology, Mar. 2017, Refereed, Not invited

Effect of physicochemical character differences on the genotoxic potency of kaolin.
Tatsuya Kato; Tatsushi Toyooka; Yuko Ibuki; Shuichi Masuda; Masatoshi Watanabe; Yukari Totsuka
Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2017, Refereed, Not invited
Corresponding

Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes.
Sachiyo Mimaki; Yukari Totsuka; Yutaka Suzuki; Chikako Nakai; Masanori Goto; Motohiro Kojima; Hirofumi Arakawa; Shigekazu Takemura; Shogo Tanaka; Shigeru Marubashi; Masahiko Kinoshita; Tomonari Matsuda; Tatsuhiro Shibata; Hitoshi Nakagama; Atsushi Ochiai; Shoji Kubo; Shoji Nakamori; Hiroyasu Esumi; Katsuya Tsuchihara
Carcinogenesis, Aug. 2016, Refereed, Not invited

Major Anaerobic Bacteria Responsible for the Production of Carcinogenic Acetaldehyde from Ethanol in the Colon and Rectum
Atsuki Tsuruya; Akika Kuwahara; Yuta Saito; Haruhiko Yamaguchi; Natsuki Tenma; Makoto Inai; Seiji Takahashi; Eri Tsutsumi; Yoshihide Suwa; Yukari Totsuka; Wataru Suda; Kenshiro Oshima; Masahira Hattori; Takeshi Mizukami; Akira Yokoyama; Takefumi Shimoyama; Toru Nakayama
ALCOHOL AND ALCOHOLISM, Jul. 2016, Refereed, Not invited

Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer.
Atsuki Tsuruya; Akika Kuwahara; Yuta Saito; Haruhiko Yamaguchi; Takahisa Tsubo; Shogo Suga; Makoto Inai; Yuichi Aoki; Seiji Takahashi; Eri Tsutsumi; Yoshihide Suwa; Hidetoshi Morita; Kenji Kinoshita; Yukari Totsuka; Wataru Suda; Kenshiro Oshima; Masahira Hattori; Takeshi Mizukami; Akira Yokoyama; Takefumi Shimoyama; Toru Nakayama
Scientific reports, Jun. 2016, Refereed, Not invited

Effects of NSAIDs on the risk factors of colorectal cancer: a mini review.
Takahiro Hamoya; Gen Fujii; Shingo Miyamoto; Mami Takahashi; Yukari Totsuka; Keiji Wakabayashi; Jiro Toshima; Michihiro Mutoh
Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2016, Refereed, Not invited

Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice
Masami Komiya; Gen Fujii; Shingo Miyamoto; Mami Takahashi; Rikako Ishigamori; Wakana Onuma; Kousuke Ishino; Yukari Totsuka; Kyoko Fujimoto; Michihiro Mutoh
CANCER SCIENCE, Nov. 2015, Refereed, Not invited

DNA adductome analyses at multiple sites of human gastric mucosa, resected for gastric cancer
Nobuya Kurabe; Ippei Ohnishi; Masako Suzuki; Yusuke Inoue; Tomoaki Kahyo; Moriya Lwaizumi; Yoshitaka Matsushima; Yukari Totsuka; Hitoshi Nakagama; Masako Kasami; Hideto Ochiai; Keigo Matsumoto; Shioto Suzuki; Fumihiko Tanioka; Haruhiko Sugimura
CANCER RESEARCH, Aug. 2015, Refereed, Not invited

Comprehensive DNA Adduct Analysis Reveals Pulmonary Inflammatory Response Contributes to Genotoxic Action of Magnetite Nanoparticles
Kousuke Ishino; Tatsuya Kato; Mamoru Kato; Tatsuhiro Shibata; Masatoshi Watanabe; Keiji Wakabayashi; Hitoshi Nakagama; Yukari Totsuka
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Feb. 2015, Refereed, Not invited
Corresponding

Exploration of the etiology of esophageal cancer in China using comprehensive DNA adduct analysis
TOTSUKA Yukari; NAKAGAMA Hitoshi
Annual Meeting of the Japanese Society of Toxicology, 2015

Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts
Masanori Goto; Kazuya Shinmura; Yoshitaka Matsushima; Kousuke Ishino; Hidetaka Yamada; Yukari Totsuka; Tomonari Matsuda; Hitoshi Nakagama; Haruhiko Sugimura
FREE RADICAL BIOLOGY AND MEDICINE, Nov. 2014, Refereed, Not invited

ゲノム中のDNA付加体部位同定の試み(Identification of the location of DNA adducts within the genome)
椎崎 一宏; 後藤 正憲; 荒井 康仁; 濱 奈津子; 柴田 龍弘; 中釜 斉; 戸塚 ゆ加里
日本癌学会総会記事, Sep. 2014, Refereed, Not invited

Validity of a self-administered food frequency questionnaire in the estimation of heterocyclic aromatic amines
Motoki Iwasaki; Tomomi Mukai; Ribeka Takachi; Junko Ishihara; Yukari Totsuka; Shoichiro Tsugane
CANCER CAUSES & CONTROL, Aug. 2014, Refereed, Not invited

Magnetite Nanoparticles Induce Genotoxicity in the Lungs of Mice via Inflammatory Response
Yukari Totsuka; Kousuke Ishino; Tatsuya Kato; Sumio Goto; Yukie Tada; Dai Nakae; Masatoshi Watanabe; Keiji Wakabayashi
NANOMATERIALS, Mar. 2014, Refereed, Not invited
Corresponding

Air pollution with particulate matter and mutagens: Relevance of Asian dust to mutagenicity of airborne particles in Japan
Tetsushi Watanabe; Tomohiro Hasei; Osamu Kokunai; Souleymane Coulibaly; Sachi Nishimura; Moe Fukasawa; Ryohei Takahashi; Yasuko Mori; Kosuke Fujita; Yuri Yoshihara; Yumi Miyake; Akane Kishi; Motoki Matsui; Fumikazu Ikemori; Kunihiro Funasaka; Akira Toriba; Kazuichi Hayakawa; Kei-Ichi Arashidani; Yohei Inaba; Nobuyuki Sera; Yuya Deguchi; Tetsurou Seiyama; Takako Yamaguchi; Masanari Watanabe; Naoko Honda; Keiji Wakabayashi; Yukari Totsuka
Genes and Environment, 2014, Refereed, Not invited

Current situation of environmental pollution in East-Asia and concern for human health - JEMS Symposium in 2013
Yukari Totsuka; Tetsushi Watanabe
Genes and Environment, 2014, Refereed, Not invited

In vivo genotoxicity of a novel heterocyclic amine, aminobenzoazepinoquinolinone-derivative (ABAQ), produced by the Maillard reaction between glucose and L-tryptophan
Yukari Totsuka; Tetsushi Watanabe; Souleymane Coulibaly; Sae Kobayashi; Marina Nishizaki; Miho Okazaki; Tomohiro Hasei; Keiji Wakabayashi; Hitoshi Nakagama
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Jan. 2014, Refereed, Not invited

A novel aromatic mutagen, 5-amino-6-hydroxy-8H-benzo[6,7]azepino[5,4,3-de]quinolin-7-one (ABAQ), induces colonic preneoplastic lesions in mice
Takahiro Kochi; Masahito Shimizu; Yukari Totsuka; Yohei Shirakami; Takayuki Nakanishi; Tetsushi Watanabe; Takuji Tanaka; Hitoshi Nakagama; Keiji Wakabayashi; Hisataka Moriwaki
Toxicology Reports, Jan. 2014, Refereed, Not invited

In vivo examination of the genotoxicity of the urban air and surface soil pollutant, 3,6-dinitrobenzo[e]pyrene, with intraperitoneal and intratracheal administration
Tatsuya Kato; Yukari Totsuka; Tomohiro Hasei; Tetsushi Watanabe; Keiji Wakabayashi; Naohide Kinae; Shuichi Masuda
ENVIRONMENTAL TOXICOLOGY, Oct. 2013, Refereed, Not invited

Effects of Fe3O4 Magnetic Nanoparticles on A549 Cells
Masatoshi Watanabe; Misao Yoneda; Ayaka Morohashi; Yasuki Hori; Daiki Okamoto; Akiko Sato; Daisuke Kurioka; Tadashi Nittami; Yoshifumi Hirokawa; Taizo Shiraishi; Kazuaki Kawai; Hiroshi Kasai; Yukari Totsuka
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Aug. 2013, Refereed, Not invited

Epidemiology of Esophageal Cancer in Japan and China
Yingsong Lin; Yukari Totsuka; Yutong He; Shogo Kikuchi; Youlin Qiao; Junko Ueda; Wenqiang Wei; Manami Inoue; Hideo Tanaka
JOURNAL OF EPIDEMIOLOGY, Jul. 2013, Refereed, Not invited

Genotoxicity of multi-walled carbon nanotubes in both in vitro and in vivo assay systems
Tatsuya Kato; Yukari Totsuka; Kousuke Ishino; Yoko Matsumoto; Yukie Tada; Dai Nakae; Sumio Goto; Shuichi Masuda; Sayaka Ogo; Masanobu Kawanishi; Takashi Yagi; Tomonari Matsuda; Masatoshi Watanabe; Keiji Wakabayashi
NANOTOXICOLOGY, Jun. 2013, Refereed, Not invited
Corresponding

Metabolic syndrome: A novel high-risk state for colorectal cancer
Kousuke Ishino; Michihiro Mutoh; Yukari Totsuka; Hitoshi Nakagama
CANCER LETTERS, Jun. 2013, Refereed, Not invited

Genotoxicity and reactive oxygen species production induced by magnetite nanoparticles in mammalian cells
Masanobu Kawanishi; Sayaka Ogo; Miho Ikemoto; Yukari Totsuka; Kousuke Ishino; Keiji Wakabayashi; Takashi Yagi
JOURNAL OF TOXICOLOGICAL SCIENCES, Jun. 2013, Refereed, Not invited

Demonstration of Cytotoxicity against Wasps by Pierisin-1: A Possible Defense Factor in the Cabbage White Butterfly
Azusa Takahashi-Nakaguchi; Yasuko Matsumoto; Masafumi Yamamoto; Kikuo Iwabuchi; Yukari Totsuka; Takashi Sugimura; Keiji Wakabayashi
PLOS ONE, Apr. 2013, Refereed, Not invited

ADP-ribosylation of guanosine by SCO5461 protein secreted from Streptomyces coelicolor
Tsuyoshi Nakano; Yuko Matsushima-Hibiya; Masafumi Yamamoto; Azusa Takahashi-Nakaguchi; Hirokazu Fukuda; Masaya Ono; Takeji Takamura-Enya; Haruyasu Kinashi; Yukari Totsuka
TOXICON, Mar. 2013, Refereed, Not invited

Induction of glandular stomach cancers in Helicobacter pylori-infected Mongolian gerbils by 1-nitrosoindole-3-acetonitrile
Satoshi Matsubara; Shinji Takasu; Tetsuya Tsukamoto; Michihiro Mutoh; Shuichi Masuda; Takashi Sugimura; Keiji Wakabayashi; Yukari Totsuka
INTERNATIONAL JOURNAL OF CANCER, Jan. 2012, Refereed, Not invited

Comparative epidemiology of gastric cancer between Japan and China
Yingsong Lin; Junko Ueda; Shogo Kikuchi; Yukari Totsuka; Wen-Qiang Wei; You-Lin Qiao; Manami Inoue
WORLD JOURNAL OF GASTROENTEROLOGY, Oct. 2011, Refereed, Not invited

Nucleotide sequence and chromosomal localization of the gene for pierisin-1, a DNA ADP-ribosylating protein, in the cabbage butterfly Pieris rapae
Masafumi Yamamoto; Azusa Takahashi-Nakaguchi; Yuko Matsushima-Hibiya; Tsuyoshi Nakano; Yukari Totsuka; Shigeo Imanishi; Jun Mitsuhashi; Masahiko Watanabe; Hitoshi Nakagama; Takashi Sugimura; Keiji Wakabayashi
GENETICA, Oct. 2011, Refereed, Not invited

Concerns over genotoxicity of nanomaterials - JEMS symposium in 2010
Yukari Totsuka; Takashi Yagi
Genes and Environment, 2011, Refereed, Not invited

In vitro and in vivo genotoxicity induced by Fullerene (C 60) and Kaolin
Yukari Totsuka; Tatsuya Kato; Shu-Ichi Masuda; Kousuke Ishino; Yoko Matsumoto; Sumio Goto; Masanobu Kawanishi; Takashi Yagi; Keiji Wakabayashi
Genes and Environment, 2011, Refereed, Not invited
Corresponding

Low-dose carcinogenicity of 2-amino-3-methylimidazo[4,5-f ]quinoline in rats: Evidence for the existence of no-effect levels and a mechanism involving p21(Cip/WAF1)
Min Wei; Hideki Wanibuchi; Dai Nakae; Hiroyuki Tsuda; Satoru Takahashi; Masao Hirose; Yukari Totsuka; Masae Tatematsu; Shoji Fukushima
CANCER SCIENCE, Jan. 2011, Refereed, Not invited

Chemical confirmation of the structure of a mutagenic aminophenylnorharman, 9-(4'-aminophenyl)-9H-pyrido[3,4-b]indole : An authentic synthesis of 9-(4'nitrophenyl)-9H- pyrido[3,4-b]indole as its relay compound
Yasuoki Murakami; Nobuyuki Imai; Tsuyoshi Miura; Takashi Sugimura; Keiji Wakabayashi; Yukari Totsuka; Noriyasu Hada; Yuusaku Yokoyama; Hideharu Suzuki; Katsuyoshi Mitsunaga
Heterocycles, Jan. 2010, Refereed, Not invited

Tumorigenesis of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), but not enhancing effects of concomitant high-fat diet, on lung carcinogenesis in female A/J mice
Hijiri Takeuchi; Kousuke Saoo; Keiko Yamakawa; Yoko Matsuda; Masanao Yokohira; Yu Zeng; Totshiya Kuno; Yukari Totsuka; Mami Takahashi; Keiji Wakabayashi; Katsumi Imaida
ONCOLOGY LETTERS, Jan. 2010, Refereed, Not invited

Molecular cloning of apoptosis-inducing Pierisin-like proteins, from two species of white butterfly, Pieris melete and Aporia crataegi
Masafumi Yamamoto; Tsuyoshi Nakano; Yuko Matsushima-Hibiya; Yukari Totsuka; Azusa Takahashi-Nakaguchi; Yasuko Matsumoto; Takashi Sugimura; Keiji Wakabayashi
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, Nov. 2009, Refereed, Not invited

Isolation and Identification of a Novel Aromatic Amine Mutagen Produced by the Maillard Reaction
Rena Nishigaki; Tetsushi Watanabe; Tetsuya Kajimoto; Atsuko Tada; Takeji Takamura-Enya; Shigeki Enomoto; Haruo Nukaya; Yoshiyasu Terao; Atsush Muroyama; Minoru Ozeki; Manabu Node; Tomohiro Hasei; Yukari Totsuka; Keiji Wakabayashi
CHEMICAL RESEARCH IN TOXICOLOGY, Sep. 2009, Refereed, Not invited

Enhancing effects of a high fat diet on 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced lung tumorigenesis in female A/J mice
Yoko Matsuda; Hijiri Takeuchi; Masanao Yokohira; Kousuke Saoo; Kyoko Hosokawa; Keiko Yamakawa; Yu Zeng; Yukari Totsuka; Keiji Wakabayashi; Katsumi Imaida
MOLECULAR MEDICINE REPORTS, Sep. 2009, Refereed, Not invited

Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems
Yukari Totsuka; Takashi Higuchi; Toshio Imai; Akiyoshi Nishikawa; Takehiko Nohmi; Tatsuya Kato; Shuich Masuda; Naohide Kinae; Kyoko Hiyoshi; Sayaka Ogo; Masanobu Kawanishi; Takashi Yagi; Takamichi Ichinose; Nobutaka Fukumori; Masatoshi Watanabe; Takashi Sugimura; Keiji Wakabayashi
PARTICLE AND FIBRE TOXICOLOGY, Sep. 2009, Refereed, Not invited
Corresponding

Induction of SCEs in CHL cells by dichlorobiphenyl derivative water pollutants, 2-phenylbenzotriazole (PBTA) congeners and river water concentrates.
Ohe T; Suzuki A; Watanabe T; Hasei T; Nukaya H; Totsuka Y; Wakabayashi K
Mutation research, Aug. 2009, Refereed, Not invited

Analysis of an RNA adduct formed from aminophenylnorharman.
Nishimura K; Totsuka Y; Higuchi T; Kawahara N; Sugimura T; Wakabayashi K
Nucleic acids symposium series (2004), 2009, Refereed, Not invited

Formation of RNA Adduct with a Novel Endogenous Mutagen and Carcinogen, Aminophenylnorharman
Yukari Totsuka; Takeji Takamura-Enya; Takashi Sugimura; Keiji Wakabayashi
CHEMICAL RESEARCH IN TOXICOLOGY, Dec. 2008, Refereed, Not invited
Corresponding

Application of a New Bioassay Technique Using Goldfish for Assessment of Water Toxicity
Yuya Deguchi; Nan Xiang Wu; Tomoyasu Toyoizumi; Shuichi Masuda; Hiroaki Nagaoka; Tetsushi Watanabe; Yukari Totsuka; Keiji Wakabayashi; Naohide Kinae
ENVIRONMENTAL TOXICOLOGY, Dec. 2008, Refereed, Not invited

Mutagenicity of 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) and benzo[a]pyrene (BaP) in the gill and hepatopancreas of rpsL transgenic zebrafish
Kimiko Amanuma; Suguru Tone; Masato Nagaya; Michi Matsumoto; Tetsushi Watanabe; Yukari Totsuka; Keiji Wakabayashi; Yasunobu Aoki
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Oct. 2008, Refereed, Not invited

Mutagenicity of 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) and benzo[a]pyrene (BaP) in the gill and hepatopancreas of rpsL transgenic zebrafish.
Amanuma K; Tone S; Nagaya M; Matsumoto M; Watanabe T; Totsuka Y; Wakabayashi K; Aoki Y
Mutation research, Oct. 2008, Refereed, Not invited

ヒトがん発生に係わる環境要因及び感受性要因に関する研究.
中釜 斉; 戸塚 ゆ加里; 山田 雅巳; 片岡 洋行; 桑原 義和; 岡田 太; 立道 昌幸; 川西 正祐; 松田 知成; 葛西 宏; 武田 健; 堤 雅弘; 白井 智之; 向所 賢一; 吉見 直己; 甲野 裕之; 今井田 克己; 島田 義也; 豊國 伸哉; 鰐渕 英機; 市瀬 孝道; 横田 淳; 渡邉 昌俊; 山添 康; 森下由紀雄; 金井 弥栄; 柳原 五吉; 平木 章夫
厚生労働省がん研究助成金による研究報告集., Sep. 2008, Not refereed, Not invited

Detection of endogenous DNA adducts, O-6-carboxymethyl-2 '-deoxyguanosine and 3-ethanesulfonic acid-2 '-deoxycytidine, in the rat stomach after duodenal reflux
Masaru Terasaki; Yukari Totsuka; Koichi Nishimura; Ken-ichi Mukaisho; Kuan-Hao Chen; Takanori Hattori; Takeji Takamura-Enya; Takashi Sugimura; Keiji Wakabayashi
CANCER SCIENCE, Sep. 2008, Refereed, Not invited
Corresponding

Carcinogenic risk of heterocyclic amines in combination - Assessment with a liver initiation model
Akihiro Hirata; Tetsuya Tsukamoto; Hiroki Sakai; Shinji Takasu; Hisayo Ban; Toshio Imai; Yukari Totsuka; Rena Nishigaki; Keiji Wakabayashi; Tokuma Yanai; Toshiaki Masegi; Masae Tatematsu
FOOD AND CHEMICAL TOXICOLOGY, Jun. 2008, Refereed, Not invited

Evidence of a Threshold-Effect for 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline Liver Carcinogenicity in F344/DuCrj Rats
Takshi Murai; Satoru Mori; Jin Seok Kang; Keiichirou Morimura; Hideki Wanibuchi; Yukari Totsuka; Shoji Fukushima
TOXICOLOGIC PATHOLOGY, Apr. 2008, Refereed, Not invited

Tumor-initiating potency of a novel heterocyclic amine, aminophenylnorharman in mouse colonic carcinogenesis model
Hiroyuki Kohno; Yukari Totsuka; Yumiko Yasui; Rikako Suzuki; Shigeyuki Sugie; Keiji Wakabayashi; Takuji Tanaka
INTERNATIONAL JOURNAL OF CANCER, Oct. 2007, Refereed, Not invited

Molecular evidence of the involvement of the nucleotide excision repair (NER) system in the repair of the mono(ADP-ribosyl)ated DNA adduct produced by pierisin-1, an apoptosis-inducing protein from the cabbage butterfly
Masanobu Kawanishi; Kazuki Matsukawa; Isao Kuraoka; Takeji Takamura-Enya; Yukari Totsuka; Yasuko Matsumoto; Masahiko Watanabe; Yue Zou; Kiyoji Tanaka; Takashi Sugimura; Keiji Wakabayashi; Takashi Yagi
CHEMICAL RESEARCH IN TOXICOLOGY, Apr. 2007, Refereed, Not invited

Analysis of the Major RNA Adduct Derived from Aminophenylnorharman, a Novel Endogenous Mutagen and Carcinogen
Yukari Totsuka; Rena Nishigaki; Takeji Takamura-Enya; Nobuo Kawahara; Takashi Sugimura; Keiji Wakabayashi
Genes and Environment, 2007, Not refereed, Not invited

Detection of aminophenylnorharman, a possible endogenous mutagenic and carcinogenic compound, in human urine samples
Rena Nishigaki; Yukari Totsuka; Hiroyuki Kataoka; Hirohumi Ushiyama; Sumio Goto; Takayuki Akasu; Tetsushi Watanabe; Takashi Sugimura; Keiji Wakabayashi
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, Jan. 2007, Refereed, Not invited

Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains
Yoshimitsu Oda; Yukari Totsuka; Keiji Wakabayashi; F. Peter Guengerich; Tsutomu Shimada
MUTAGENESIS, Nov. 2006, Refereed, Not invited

The possible involvement of mutagenic and carcinogenic heterocyclic amines in human cancer
Yukari Totsuka; Rena Nishigaki; Takashi Sugimura; Keiji Wakabayashi
Acrylamide and Other Hazardous Compounds in Heat-Treated Foods, Oct. 2006, Refereed, Not invited

Purification and molecular cloning of a DNA ADP-ribosylating protein, CARP-1, from the edible clam Meretrix lamarckii
Tsuyoshi Nakano; Yuko Matsushima-Hibiya; Masafumi Yamamoto; Shigeki Enomoto; Yasuko Matsumoto; Yukari Totsuka; Masahiko Watanabe; Takashi Sugimura; Keiji Wakabayashi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Sep. 2006, Refereed, Not invited

Existence of a no effect level for MeIQx hepatocarcinogenicity on a background of thioacetamide-induced liver damage in rats
JS Kang; H Wanibuchi; K Morimura; Y Totsuka; Yoshimura, I; S Fukushima
CANCER SCIENCE, Jun. 2006, Refereed, Not invited

Absence of in vivo genotoxic potential and tumor initiation activity of kojic acid in the rat thyroid
T Tamura; K Mitsumori; Y Totsuka; K Wakabayashi; R Kido; H Kasai; M Nasu; M Hirose
TOXICOLOGY, May 2006, Refereed, Not invited

Induction of gastric GIST in rat and establishment of GIST cell line
K Mukaisho; K Miwa; Y Totsuka; A Shimomura; H Sugihara; K Wakabayashi; T Hattori
CANCER LETTERS, Jan. 2006, Refereed, Not invited

Structures and biological properties of DNA adducts derived from N-nitroso bile acid conjugates
Y Totsuka; R Nishigaki; S Enomoto; T Takamura-Enya; K Masumura; T Nohmi; N Kawahara; T Sugimura; K Wakabayashi
CHEMICAL RESEARCH IN TOXICOLOGY, Oct. 2005, Refereed, Not invited

ラットにおけるコリン欠乏アミノ酸食前処置のaminophenylnorharmanの肝臓および大腸発がん性に及ぼす影響
高橋 正一; 戸塚 ゆ加里; 高橋 真美; 植松 史行; 五十嵐 麻希; 吉田 緑; 前川 昭彦; 若林 敬二; 中江 大
日本癌学会総会記事, Sep. 2005

Involvement of nucleotide excision repair (NER) system in repair of mono ADP-ribosylated dG adducts produced by pierisin-1, a cytotoxic protein from cabbage butterfly
B Shiotani; M Watanabe; Y Totsuka; T Sugimura; K Wakabayashi
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, May 2005, Refereed, Not invited

Lack of elevated liver carcinogenicity of aminophenylnorharman in p53-deficient mice
T Iidaka; T Tsukamoto; Y Totsuka; A Hirata; H Sakai; N Shirai; M Yamamoto; K Wakabayashi; T Yanai; T Masegi; LA Donehower; M Tatematsu
CANCER LETTERS, Jan. 2005, Refereed, Not invited

Induction of DNA-adducts and increase of 8-hydroxy-2-deoxyguanosine, but no development of preneoplastic lesions in offspring liver with transplacental and trans-breast milk exposure to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MelQx) in rats
T Ichihara; H Wanibuchi; Y Totsuka; K Morimura; M Wei; D Nakae; S Fukushima
CANCER SCIENCE, Dec. 2004, Refereed, Not invited

Carcinogenicity of aminophenylnorharman, a possible novel endogenous mutagen, formed from norharman and aniline, in F344 rats
T Kawamori; Y Totsuka; N Uchiya; T Kitamura; H Shibata; T Sugimura; K Wakabayashi
CARCINOGENESIS, Oct. 2004, Refereed, Not invited

Identification of cytochrome P-450s involved in the formation of APNH from norharman with aniline
R Nishigaki; Y Totsuka; T Takamura-Enya; T Sugimura; K Wakabayashi
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Aug. 2004, Refereed, Not invited

Identification of cytochrome P-450s involved in the formation of APNH from norharman with aniline.
Nishigaki R; Totsuka Y; Takamura-Enya T; Sugimura T; Wakabayashi K
Mutation research, Aug. 2004, Refereed, Not invited

Mechanisms of co-mutagenic action of norharman
Totsuka Yukari
Environmental Mutagen Research, Apr. 2004

Mutagens formed from beta-carbolines with aromatic amines
Y Totsuka; T Takamura-Enya; R Nishigaki; T Sugimura; K Wakabayashi
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, Mar. 2004, Not refereed, Not invited

Detection of initiating and promoting activity of aminophenylnorharman with a five-week in vivo initiation assay
Takeshi Iidaka; Hiroki Sakai; Tetsuya Tsukamoto; Masami Yamamoto; Norimitsu Shirai; Yukari Totsuka; Keiji Wakabayashi; Tokuma Yanai; Toshiaki Masegi; Masae Tatematsu
Journal of Toxicologic Pathology, 2004, Not refereed, Not invited

Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse
K Masumura; Y Totsuka; K Wakabayashi; T Nohmi
CARCINOGENESIS, Dec. 2003, Refereed, Not invited

Analysis of HPRT and supF mutations caused by pierisin-1, a guanine specific ADP-ribosylating toxin derived from the cabbage butterfly
Y Totsuka; M Kawanishi; R Nishigaki; K Matsukawa; T Yagi; T Takamura-Enya; M Watanabe; T Sugimura; K Wakabayashi
CHEMICAL RESEARCH IN TOXICOLOGY, Aug. 2003, Refereed, Not invited

Post-initiation inhibition of MeIQx hepatocarcinogenesis in rats by cysteine.
Ogawa M; Wanibuchi H; Nishkawa T; Yano Y; Otani S; Totsuka Y; Wakabayashi K; Nakae D; Fukushima S
Osaka city medical journal, Jun. 2003, Refereed, Not invited

Analysis of estrogenic activity of foodstuffs and cigarette smoke condensates using a yeast estrogen screening method
T Takamura-Enya; J Ishihara; S Tahara; S Goto; Y Totsuka; T Sugimura; K Wakabayashi
FOOD AND CHEMICAL TOXICOLOGY, Apr. 2003, Not refereed, Not invited

Structure of DNA adduct formed with aminophenylnorharman, being responsible for the comutagenic action of norharman with aniline
Y Totsuka; T Takamura-Enya; N Kawahara; R Nishigaki; T Sugimura; K Wakabayashi
CHEMICAL RESEARCH IN TOXICOLOGY, Oct. 2002, Refereed, Not invited

Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine
S Fukushima; H Wanibuchi; K Morimura; M Wei; D Nakae; Y Konishi; H Tsuda; N Uehara; K Imaida; T Shirai; M Tatematsu; T Tsukamoto; M Hirose; F Furukawa; K Wakabayashi; Y Totsuka
JAPANESE JOURNAL OF CANCER RESEARCH, Oct. 2002, Refereed, Not invited

In vitro and in vivo formation of aminophenylnorharman from norharman and aniline
Y Totsuka; H Kataoka; T Takamura-Enya; T Sugimura; K Wakabayashi
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, Sep. 2002, Refereed, Not invited

Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline
T Ohe; T Takata; Y Maeda; Y Totsuka; N Hada; A Matsuoka; N Tanaka; K Wakabayashi
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Mar. 2002, Refereed, Not invited

Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline.
Ohe T; Takata T; Maeda Y; Totsuka Y; Hada N; Matsuoka A; Tanaka N; Wakabayashi K
Mutation research, Mar. 2002, Refereed, Not invited

Metabolism of sulphobromophthalein II. Species differences between rats, guinea-pigs and rabbits
K Sano; Y Totsuka; Y Ikegami; T Uesugi
JOURNAL OF PHARMACY AND PHARMACOLOGY, Feb. 2002, Refereed, Not invited

Mono(ADP-ribosyl)ation of DNA by apoptosis-inducing protein, pierisin.
Watanabe M; Takamura-Enya T; Kanazawa T; Totsuka Y; Matsushima-Hibiya Y; Koyama K; Sugimura T; Wakabayashi K
Nucleic acids research. Supplement (2001), 2002, Refereed, Not invited

Mono(ADP-ribosyl)ation of 2 '-deoxyguanosine residue in DNA by an apoptosis-inducing protein, pierisin-1, from cabbage butterfly
T Takamura-Enya; M Watanabe; Y Totsuka; T Kanazawa; Y Matsushima-Hibiya; K Koyama; T Sugimura; K Wakabayashi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Oct. 2001, Not refereed, Not invited

Testicular toxicity in F344 rats by aminophenylnorharman, formed from Norharman and Aniline
Y Totsuka; T Kawamori; S Hisada; K Mitsumori; J Ishihara; T Sugimura; K Wakabayashi
TOXICOLOGY AND APPLIED PHARMACOLOGY, Sep. 2001, Refereed, Not invited

Metabolism of sulphobromophthalein I: positional isomers of sulphobromophthalein monoglutathione conjugate
K Sano; Y Totsuka; Y Ikegami; T Uesugi
JOURNAL OF PHARMACY AND PHARMACOLOGY, Jul. 2001, Refereed, Not invited

Oxidative DNA damage by an N-hydroxy metabolite of the mutagenic compound formed from norharman and aniline
S Ohnishi; M Murata; S Oikawa; Y Totsuka; T Takamura; K Wakabayashi; S Kawanishi
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Jul. 2001, Refereed, Not invited

Structures of mutagens produced by the co-mutagen norharman with o- and m-toluidine isomers
Noriyasu Hada; Yukari Totsuka; Takeji Enya; Kumiko Tsurumaki; Mariko Nakazawa; Nobuo Kawahara; Yasuoki Murakami; Yuusaku Yokoyama; Takashi Sugimura; Keiji Wakabayashi
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, Jun. 2001, Refereed, Not invited

Induction of liver preneoplastic lesions by aminophenylnorharman, formed from norharman and aniline, in male F344 rats
T Kawamori; Y Totsuka; J Ishihara; N Uchiya; T Sugimura; K Wakabayashi
CANCER LETTERS, Feb. 2001, Refereed, Not invited

Delay of DNA-adduct repair and severe toxicity in xeroderma pigmentosum group A gene (XPA) deficient mice treated with 2-amino-1-methyl-6-phenyl- imidazo [4,5-b] pyridine (PhIP)
Katsumi Imaida; Kumiko Ogawa; Satoru Takahashi; Takayasu Ito; Tsuyoshi Yamaguchi; Yukari Totsuka; Keiji Wakabayashi; Kiyoji Tanaka; Nobuyuki Ito; Tomoyuki Shirai
Cancer Letters, Mar. 2000, Refereed, Not invited

Quantification of the co-mutagenic beta-carbolines, norharman and harman, in cigarette smoke condensates and cooked foods
Y Totsuka; H Ushiyama; J Ishihara; R Sinha; S Goto; T Sugimura; K Wakabayashi
CANCER LETTERS, Sep. 1999, Refereed, Not invited

Structural determination of a mutagenic aminophenylnorharman produced by the co-mutagen norharman with aniline
Y Totsuka; N Hada; K Matsumoto; N Kawahara; Y Murakami; Y Yokoyama; T Sugimura; K Wakabayashi
CARCINOGENESIS, Nov. 1998, Refereed, Not invited

Inhibitory effects of antioxidants on formation of heterocyclic amines
A Oguri; M Suda; Y Totsuka; T Sugimura; K Wakabayashi
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, Jun. 1998, Refereed, Not invited

Identification of estrogen-modified nucleosides from calf thymus DNA reacted with 6-hydroxyestrogen 6-sulfates
Shinji Itoh; Toshiaki Hirai; Yukari Totsuka; Hidetoshi Takagi; Yumiko Tashiro; Koji Wada; Keiji Wakabayashi; Shinya Shibutani; Itsuo Yoshizawa
Chemical Research in Toxicology, 1998, Refereed, Not invited

Reduction in formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced aberrant crypt foci in the rat colon by docosahexaenoic acid (DHA)
M Takahashi; Y Totsuka; M Masuda; K Fukuda; A Oguri; K Yazawa; T Sugimura; K Wakabayashi
CARCINOGENESIS, Oct. 1997, Not refereed, Not invited

Human exposure to mutagenic/carcinogenic heterocyclic amines and comutagenic beta-carbolines
K Wakabayashi; Y Totsuka; K Fukutome; A Oguri; H Ushiyama; T Sugimura
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, May 1997, Refereed, Not invited

Formation of DNA adducts by the co-mutagen norharman with aromatic amines
M Mori; Y Totsuka; K Fukutome; T Yoshida; T Sugimura; K Wakabayashi
CARCINOGENESIS, Jul. 1996, Refereed, Not invited

Human exposure to carcinogenic heterocyclic amines and their mutational fingerprints in experimental animals
M Nagao; K Wakabayashi; T Ushijima; M Toyota; Y Totsuka; T Sugimura
ENVIRONMENTAL HEALTH PERSPECTIVES, May 1996, Refereed, Not invited

Presence of N2-(deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo4,5-flqumoxaline (dG-C8-MeIQx) in human tissues
Yukari Totsuka; Kazuo Fukutome; Mami Takahashi; Satoru Takahashi; Akihiro Tada; Takashi Sugimura; Keiji Wakabayashi
Carcinogenesis, 1996, Not refereed, Not invited

Norharman and Harman in Human Urine
Hirofumi Ushiyama; Atsuko Oguri; Yukari Totsuka; Takashi Sugimura; Keiji Wakabayashi; Hajime Itoh
Proceedings of the Japan Academy, Series B, 1995, Refereed, Not invited

マウス正常組織由来オルガノイドを用いた遺伝毒性解析法の構築
小宮 雅美; 落合 雅子; 今井 俊夫; 戸塚 ゆ加里
日本薬学会第143年会要旨集, Mar. 2023, Not refereed
Last

加熱式タバコの遺伝毒性評価
広田 航太郎; 山口 大雅; 小宮 雅美; 稲葉 洋平; 加藤 孝一; 戸塚 ゆ加里
日本薬学会第143年会要旨集, Mar. 2023
Last

次世代シークエンサーにより環境要因と ヒト発がんの関係を解明する
戸塚 ゆ加里; 小宮雅美; 永井桃子; 加藤 護
日本薬学会第143年会要旨集, Mar. 2023, Not refereed, Not invited
Lead

New horizons of DNA adductome for exploring environmental causes of cancer
Yukari Totsuka
13th International Conference on Environmental Mutagens, Aug. 2022, Not refereed, Invited
Lead

Next generation sequencing elucidates the association between environmental factors and human cancer development
戸塚ゆ加里; 戸塚ゆ加里; 小宮雅美; 松田知成; 加藤護
日本癌学会学術総会抄録集(Web), 2022

In vitro formations of homo and heterodimer of urinary bladder carcinogens, monocyclic aromatic amines
小林琢磨; 豊田武士; 吉岡泰淳; 村井尚子; 岸本真治; 松下幸平; 山田貴宣; 山田貴宣; 小川久美子; 渡辺賢二; 高村岳樹; 戸塚ゆ加里; 戸塚ゆ加里; 若林敬二; 三好規之
日本環境変異原ゲノム学会大会プログラム・要旨集, 2021

単環芳香族アミン化合物の試験管内反応による二量体形成
小林琢磨; 田島悠也; 豊田武士; 岸本真治; 松下幸平; 山田貴宣; 山田貴宣; 小川久美子; 渡辺賢二; 高村岳樹; 戸塚ゆ加里; 戸塚ゆ加里; 若林敬二; 三好規之
がん予防学術大会プログラム・抄録集, 2021

アスベスト誘発ラット中皮腫におけるゲノム変異の特徴
赤塚 慎也; 蒋 麗; エルザワハリ・アスマ; 加藤 護; 戸塚 ゆ加里; 柴田 龍弘; 豊國 伸哉
日本癌学会総会記事, Oct. 2020

Multifocal origin of occupational cholangiocarcinoma revealed by comparison of multilesion mutational profiles.
Sachiyo Mimaki; Masahiko Watanabe; Masahiko Kinoshita; Riu Yamashita; Hiroshi Haeno; Shigekazu Takemura; Shogo Tanaka; Shigeru Marubashi; Yukari Totsuka; Tatsuhiro Shibata; Hitoshi Nakagama; Atsushi Ochiai; Shoji Nakamori; Shoji Kubo; Katsuya Tsuchihara
Carcinogenesis, 14 May 2020, Not refereed, Not invited

アスベスト誘発ラット中皮腫におけるゲノム変異の特徴解析
赤塚 慎也; 蒋 麗; 戸塚 ゆ加里; 加藤 護; エルザワハリ・アスマ; 柴田 龍弘; 豊國 伸哉
日本病理学会会誌, Mar. 2020

Quest for metabolite in urine of rats exposed to o-anisidine
小林琢磨; 田島悠也; 豊田武士; 岸本真治; 松下幸平; 山田貴宣; 山田貴宣; 小川久美子; 渡辺賢二; 高村岳樹; 戸塚ゆ加里; 若林敬二; 三好規之
日本環境変異原学会大会プログラム・要旨集, 2020

職業性胆管がんの変異プロファイルより推定されたがん化に重要な遺伝子(Estimated acquired gene variants contributing to the carcinogenesis of occupational cholangiocarcinoma)
三牧 幸代; 渡辺 雅彦; 木下 正彦; 戸塚 ゆ加里; 柴田 龍弘; 落合 淳志; 中森 正二; 久保 正二; 土原 一哉
日本癌学会総会記事, Sep. 2018

全ゲノム解析データを用い、化学物質のヒト発がんへの関与を明らかにする(Whole genome sequencing analysis elucidates the interaction between environmental factors and causes of human cancer)
戸塚 ゆ加里; 松田 知成; 加藤 護; Elzawahry Asmaa; 十時 泰; 柴田 龍弘; 中釜 斉
日本癌学会総会記事, Sep. 2018, Not refereed, Not invited

全ゲノム解析データを用い,化学物質のヒト発がんへの関与を明らかにする
戸塚ゆ加里; 佐藤春菜; 松田知成; 加藤護; ELZAWAHRY Asmaa; 遠藤治
日本環境変異原学会大会プログラム・要旨集, 2018

モデル生物を用いた化学物質により誘発される変異シグネチャーの解析
秋場望; 秋場望; 佐藤春菜; 松田知成; 遠藤治; 稲葉一穂; 戸塚ゆ加里
日本環境変異原学会大会プログラム・要旨集, 17 Oct. 2017, Not refereed, Not invited

マウス正常上皮の3次元培養系を用いる化学発がん過程の早期変化検出系
今井 俊夫; 落合 雅子; 成瀬 美衣; 松浦 哲也; 戸塚 ゆ加里; 筆宝 義隆
日本癌学会総会記事, Sep. 2017, Not refereed, Not invited

Identification of gastric cancer-related DNA adducts by DNA adductome analysis
Y. Iwashita; Ohnishi, I; N. Kurabe; T. Yamashita; S. Ohtsuka; M. Suzuki; T. Kahyo; M. Iwaizumi; Y. Matsushima; Y. Totsuka; H. Ochiai; K. Matsumoto; S. Suzuki; H. Mori; T. Ozawa; F. Tanioka; H. Sugimura
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Sep. 2017, Not refereed, Not invited

次世代シークエンサーとDNAアダクトーム解析の統合による発がん要因の探索
戸塚ゆ加里; 善家茜; 古川英作; 加藤護; 十時泰; 柴田龍弘; 中釜斉
日本環境変異原学会大会プログラム・要旨集, 31 Oct. 2016, Not refereed, Not invited

血漿中cis-4-decenalの大腸がんリスクマーカーとしての可能性
伴野 勧; 山地 太樹; 岩崎 基; 成島 大智; 加藤 護; 戸塚 ゆ加里; 三好 規之; 今井 俊夫
日本癌学会総会記事, Oct. 2016, Not refereed, Not invited

職業性胆管がん 症例に認められた同時多発腫瘍の変異プロファイルの比較
三牧 幸代; 中森 正二; 久保 正二; 木下 正彦; 戸塚 ゆ加里; 中釜 斉; 落合 淳志; 江角 浩安; 土原 一哉
日本癌学会総会記事, Oct. 2016, Not refereed, Not invited

DNAアダクトーム解析により中国食道癌の要因を探索する
戸塚 ゆ加里; 林 櫻松; 加藤 護; 十時 泰; 柴田 龍弘; 松島 芳隆; 中釜 斉
日本癌学会総会記事, Oct. 2016, Not refereed, Not invited

印刷業従業者胆管癌のゲノム変異より明らかとなった変異原物質の特徴
三牧 幸代; 戸塚 ゆ加里; 落合 淳志; 久保 正二; 中森 正二; 中釜 斉; 江角 浩安; 土原 一哉
日本癌学会総会記事, Oct. 2015, Not refereed, Not invited

発癌因子ワークショップ(禁煙指導講習会) 喫煙関連DNAアダクトのヒト組織内での検出
倉部 誠也; 大西 一平; 鈴木 雅子; 井上 裕介; 華表 友暁; 戸塚 ゆ加里; 中釜 斉; 嵩 眞佐子; 鈴木 潮人; 船井 和仁; 谷岡 書彦; 椙村 春彦
肺癌, Oct. 2015, Not refereed, Not invited

疫学が提案するポストゲノムがん研究 DNA付加体の網羅的解析(アダクトーム)により発がん要因を探索する
戸塚 ゆ加里; 林 櫻松; 加藤 護; 十時 泰; 柴田 龍弘; 松島 芳隆; 中釜 斉
日本癌学会総会記事, Oct. 2015, Not refereed, Not invited

質量分析機器を用いたDNA付加体の網羅的解析による食道癌発症要因の解明
戸塚ゆ加里; LIN Yingsong; 加藤護; 十時泰; 柴田龍弘; 松島芳隆; 中釜斉
衛生薬学・環境トキシコロジー講演要旨集, 31 Aug. 2015, Not refereed, Not invited

ヒトDNAグリコシラーゼTDGはエテノDNA付加体と誤対合するチミンの除去修復に関わる
新村和也; 後藤正憲; 後藤正憲; 松島芳隆; 石野孔祐; 戸塚ゆ加里; 松田知成; 中釜斉; 椙村春彦
日本酸化ストレス学会学術集会プログラム・抄録集, 29 May 2015, Not refereed, Not invited

胃粘膜の多数部位のDNAアダクトーム解析(DNA adductome analyses at multiple sites of human gastric mucosa, resected for gastric cancer)
倉部 誠也; 大西 一平; 井上 裕介; 華表 友暁; 戸塚 ゆ加里; 中釜 斉; 嵩 眞佐子; 鈴木 潮人; 谷岡 書彦; 椙村 春彦
日本病理学会会誌, Mar. 2015, Not refereed, Not invited

S2-2 Exploration of cancer etiology using whole genome/exome analysis and comprehensive DNA adduct analysis(Symposium 2 Kitaji Mochizuki Memorial Symposium Molecular Mechanism of Mutagenesis)
Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2015

P-056 Influence of GSH S-transferase on the mutagenicity induced by dichloromethane and 1,2-dichloropropane, being responsible for occupational cholangiocarcinoma(Poster Sessions)
Akiba Nozomi; Shiizaki Kazuhiro; Endo Osamu; Mimaki Sachiyo; Tsuchihara Katsuya; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2015, Not refereed, Not invited

職業性胆管がんの候補物質、ジクロロメタンと1,2-ジクロロプロパンの遺伝毒性分析(Genotoxicity analyses of dichloromethane and 1,2-dichloropropane, being responsible for occupational bile duct cancer)
後藤 正憲; 戸塚 ゆ加里; 土原 一哉; 三牧 幸代; 尾島 英知; 柴田 龍弘; 落合 淳志; 中釜 斉
日本癌学会総会記事, Sep. 2014, Not refereed, Not invited

O-1(P-004) A multidisciplinary approach to explore the etiology of esophageal cancer in China(Platform Session 1)
Ikeda Akane; Kato Mamoru; Shibata Tatsuhiro; Kurosaka Isao; Lin Yingsong; Matsushima Yoshitaka; Endo Osamu; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2014

P-005(O-2) Mutation signature analysis of occupational cholangiocarcinoma and dichrolopropane-exposed cells(Poster Sessions)
Goto Masanori; Mimaki Sachiyo; Kubo Shoji; Tsuchihara Katsuya; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2014

O-2(P-005) Mutation signature analysis of occupational cholangiocarcinoma and dichrolopropaneexposed cells(Platform Session 1)
Goto Masanori; Mimaki Sachiyo; Kubo Shoji; Tsuchihara Katsuya; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2014

P-038 Establishment of novel genotoxicity evaluation systems suitable for nanomaterials based on nanotoxicologic mechanisms(Poster Sessions)
Fukai Emi; Watanabe Masatoshi; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2014

P-014 Comprehensive analysis of DNA adducts in the liver of rats treated with non-genotoxic carcinogen, 1,4-dioxane(Poster Sessions)
Akimoto Shuntaro; Kato Mamoru; Shibata Tatsuhiro; Endo Osamu; Wei Min; Nakagama Hitoshi; Wanibuchi Hideki; Fukushima Shoji; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2014

P-010 Single molecule detection of the DNA modification within the genome(Poster Sessions)
Shiizaki Kazuhiro; Goto Masanori; Hama Natsuko; Arai Yasuhito; Shibata Tatsuhiro; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2014

P-004(O-1) A multidisciplinary approach to explore the etiology of esophageal cancer in China(Poster Sessions)
Ikeda Akane; Kato Mamoru; Shibata Tatsuhiro; Kurosaka Isao; Lin Yingsong; Matsushima Yoshitaka; Endo Osamu; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2014

P-040 Particle properties and the genotoxicity of titanium dioxide(Poster Sessions)
Yoneda Reimi; Kawanishi Masanobu; Totsuka Yukari; Yagi Takashi
日本環境変異原学会大会プログラム・要旨集, 2014

化学物質、放射線と発がん 1,2-DCP、DCM曝露歴のある印刷工胆管癌に認められた高頻度ゲノム変異(Biological effects of Ionizing radiation and genotoxic chemotherapeutic agents Hypermutation in cholangiocarcinoma of an offset color proof-printing worker exposed to 1,2-DCP and/or DCM)
中釜 斉; 戸塚 ゆ加里; 三牧 幸代; 中森 正二; 鈴木 穣; 柴田 龍弘; 落合 淳志; 土原 一哉
日本癌学会総会記事, Oct. 2013, Not refereed, Not invited

職業性胆管がんの原因候補物質であるハロゲン系炭化水素由来のDNA付加体及び変異原性の解析(DNA adduct formation and mutagenicity of Haloalkanes responsible for bile duct cancer developed in the printing industry)
石野 孔輔; 戸塚 ゆ加里; 松島 芳隆; 鰐渕 英機; 魏 民; 山野 荘太郎; 中森 正二; 柴田 龍弘; 土原 一哉; 落合 淳志; 中釜 斉
日本癌学会総会記事, Oct. 2013, Not refereed, Not invited

エテノアダクトにおけるヒト塩基除去修復酵素TDGの修復機構(The repair mechanism of human base excision repair enzyme TDG on etheno-DNA adducts)
後藤 正憲; 新村 和也; 松島 芳隆; 石野 孔祐; 戸塚 ゆ加里; 中釜 斉; 椙村 春彦
日本癌学会総会記事, Oct. 2013, Not refereed, Not invited

P-024 Analyses of gpt mutations and their spectra induced by dichloromethane and 1,2-dichloro-propane, being responsible for occupational bile duct cancer(Poster presentation)
Banba Mei; Goto Sumio; Matsushima Yoshitaka; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2013

P-056 Establishment of an in vitro toxicity assessment system for nanomaterials(Poster presentation)
Fukai Emi; Watanabe Masatoshi; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2013

P-058(O-8) Mutagenicity test in human cells using the shuttle plasmid containing dichloromethane-derived DNA adducts(Poster presentation)
Goto Masanori; Matsushima Yoshitaka; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2013

P-059 Genotoxicity and Surface treatment of titanium dioxide nanoparticles in human skin cultured cells(Poster presentation)
Yoneda Reimi; Kawanishi Masanobu; Totsuka Yukari; Yagi Takashi
日本環境変異原学会大会プログラム・要旨集, 2013

P-028 Comprehensive analysis of DNA adducts (DNA adductome analysis) derived from haloalkanes responsible for bile duct cancer developed in workers of printing industry(Poster presentation)
Tsujita Toshihiro; Ishino Kousuke; Kato Mamoru; Shibata Tatsuhiro; Goto Sumio; Wei Min; Matsushima Yoshitaka; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2013

P-088 Identification of the locations of DNA modification within the genome(Poster presentation)
Ono Aya; Goto Masanori; Arai Yasuhito; Shibata Tatushiro; Matsushima Yoshitaka; Nakagama Hitosih; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2013

P-018 In vivo mutagenicity of aminobenzoazepinoquinolinone derivative (ABAQ) formed from L-tryptophan and glucose by the Maillard reaction(I. Mutagenicity・Genotoxicity,Poster Presentation)
Sakaizawa Aya; Goto Sumio; Wakabayashi Keiji; Watanabe Tetsushi; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2012

W-6 Mechanisms of Genotoxicity Induced By Nanomaterials(Workshop "Effect of Environmental Mutagens・Carcinogens on Respiratory Disease Development")
Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2012

P-038 Analysis of DNA adducts derived from dihaloalkanes(I. Mutagenicity・Genotoxicity,Poster Presentation)
Totsuka Yukari; Ishino Kousuke; Matsushima Yoshitaka; Nakagama Hitoshi
日本環境変異原学会大会プログラム・要旨集, 2012

P-037 Adductome analysis of DNA adducts in lungs of mice exposed to magnetite (MGT)(I. Mutagenicity・Genotoxicity,Poster Presentation)
Sekine Akihiro; Ishino Kousuke; Goto Sumio; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2012

P-036 Adduct-DNA Immunoprecipitation (A-DIP) method for concentration of DNA-adducts in human genome(I. Mutagenicity・Genotoxicity,Poster Presentation)
Ono Aya; Nakano Tsuyoshi; Nakagama Hitoshi; Matsushima Yoshitaka; Nunoshiba Tatsuo; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2012

P-034 Clarification of the mechanism of genotoxicity caused by kaolin(I. Mutagenicity・Genotoxicity,Poster Presentation)
Ikemoto Miho; Kawanishi Masanobu; Totsuka Yukari; Wakabayashi Kenji; Yagi Takashi
日本環境変異原学会大会プログラム・要旨集, 2012

P-130(O-8) Exploration of novel DNA adducts using comprehensive adduct analysis (DNA adductome analysis)(VII. Genotoxicity Test (II),Poster Presentation)
Ishino Kousuke; Sekine Akihiro; Goto Sumio; Nakagama Hitoshi; Totsuka Yukari
日本環境変異原学会大会プログラム・要旨集, 2012

P-078 Formation of a novel mutagen, ABAQ, under diabetic condition in vivo(Poster Presentation)
Yamada Masanori; Shimamura Yuko; Totsuka Yukari; Inaba Naoyuki; Coulibaly Souleymane; Tamura Yuka; Hasei Tomohiro; Wakabayashi Keiji; Watanabe Tetsushi; Masuda Shuichi
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 20 Oct. 2011, Not refereed, Not invited

ナノマテリアルによりマウス肺に誘発されるDNA付加体の網羅的解析
ISHINO KOSUKE; KATO TATSUYA; MATSUDA TOMONARI; TOTSUKA YUKARI; NAKAGAMA HITOSHI
日本環境変異原学会大会プログラム・要旨集, 20 Oct. 2011, Not refereed, Not invited

P-025 Differences in DNA damaging potency and incorporation rate into cultured mammalian cells of differently-originated kaolins(Poster Presentation)
Kato Tatsuya; Ishino Kousuke; Toyooka Tatsushi; Ibuki Yuko; Watanabe Masatoshi; Wakabayashi Keiji; Masuda Shuichi; Totsuka Yukari; Nakagama Hitoshi
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 20 Oct. 2011, Not refereed, Not invited

P-066 Contribution of homologous recombination to nanomaterial-induced micronucleus induction(Poster Presentation)
Ikemoto Miho; Kawanishi Masanobu; Totsuka Yukari; Wakabayashi Keiji; Yagi Takashi
日本環境変異原学会大会プログラム・要旨集, 2011

P-029 In vivo mutagenicity of aminobenzoazepinoquinolinone derivative (ABAQ) formed from L-tryptophan and glucose by the Maillard reaction(Poster Presentation)
Otsuka Kumi; Totsuka Yukari; Wakabayashi Keiji; Nunoshiba Tatsuo; Watanabe Tetsushi; Nakagama Hitoshi
日本環境変異原学会大会プログラム・要旨集, 2011

ヒトがん発生に係わる環境要因及び感受性要因の掌握とその制御に基づいたがん予防法の開発に資する基盤的研究
中釜斉; 今井田克己; 豊國伸哉; 鰐渕英機; 塚本徹哉; 荒川博文; 戸塚ゆ加里; 片岡洋行; 岡田太; 松田知成; 横田淳; 野口雅之; 松尾恵太郎; 柴田龍弘; 湯浅保仁
国立がん研究センターがん研究開発費総括研究報告書(Web), 2011, Not refereed, Not invited

P-089 In vivo Genotoxicity induced by Nanoparticles, Multi-wall carbon nanotube (MWCNT) and magnetite (MGT)(Poster Presentation)
Matsumoto Yoko; Ishino Kousuke; Kato Tatsuya; Masuda Shuichi; Goto Sumio; Sugimura Takashi; Wakabayashi Keiji; Totsuka Yukari
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 29 Oct. 2010, Not refereed, Not invited

P-090 Analysis of DNA adduct formation in mice exposed to nanomaterials(Poster Presentation)
Ishino Kousuke; Kato Tatsuya; Masuda Shuichi; Matsuda Tomonari; Sugimura Takashi; Wakabayashi Keiji; Totsuka Yukari
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 29 Oct. 2010, Not refereed, Not invited

P-102 Mutagenicity and anti-cancer activity of DNA ADP-ribosylating protein, pierisin-1(Poster Presentation)
Koshida Hideshi; Yamamoto Masafumi; Totsuka Yukari; Nakano Tsuyoshi; Hibiya Yuko; Nakaguchi Azusa; Ohta Toshihiro; Akiyoshi Kazunari; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2010

P-046 Genotoxicity of amino benzoazepinoquinolinone derivative formed by the Maillard reaction(Poster Presentation)
Kobayashi Sae; Nishizaki Marina; Ozeki Minoru; Kajimoto Tetsuya; Node Manabu; Hasei Tomohiro; Totsuka Yukari; Kawanishi Masanobu; Yagi Takashi; Wakabayashi Keiji; Watanabe Tetsushi
日本環境変異原学会大会プログラム・要旨集, 2010

P-004 Increased formation of oxidative damage-related DNA adducts in obese model mice(Poster Presentation)
Kato Tatsuya; Totsuka Yukari; Tasato Rina; Wakabayashi Keiji; Masuda Shuichi
日本環境変異原学会大会プログラム・要旨集, 2010

P-028 In vivo Genotoxicity induced by Nanoparticles(Genotoxicity,Poster Session)
Matsumoto Yoko; Totsuka Yukari; Masuda Shuichi; Kato Tatsuya; Nohmi Takehiko; Goto Sumio; Sugimura Takashi; Wakabayashi Keiji
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 06 Nov. 2009, Not refereed, Not invited

P-073 Genotoxicity of 3,6-dinitrobenzo[e]pyrene in in vivo(Environmental mutagens,Poster Session)
Kato Tatsuya; Masuda Shuichi; Ichinose Takamichi; Hasei Tomohiro; Watanabe Tetsushi; Totsuka Yukari; Wakabayashi Keiji; Kinae Naohide
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 06 Nov. 2009, Not refereed, Not invited

O13-006 抗がん剤調製時の環境曝露(一般演題 口頭発表,調剤・処方鑑査・リスクマネジメント/医薬品情報・データベース/有害事象・副作用,医療薬学の創る未来 科学と臨床の融合)
西垣 玲奈; 戸塚 ゆ加里; 若林 敬二; 山本 弘史
日本医療薬学会年会講演要旨集, 15 Sep. 2009

Induction of SCEs in CHL cells by dichlorobiphenyl derivative water pollutants, 2-phenylbenzotriazole (PBTA) congeners and river water concentrates
Takeshi Ohe; Aki Suzuki; Tetsushi Watanabe; Tomohiro Hasei; Haruo Nukaya; Yukari Totsuka; Keiji Wakabayashi
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Aug. 2009, Not refereed, Not invited

P-075 Analysis of protein adducts derived from N-nitroso bile acid conjugates(Environmental mutagens,Poster Session)
Nishimura Koichi; Totsuka Yukari; Kawahara Nobuo; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2009

P-036 Phosphodiester adducts derived from N-Acetoxy-APNH with deoxynucleotide-3'-monophosphate(DNA damages,Poster Session)
Kirigaya Hidemasa; Nishimura Koichi; Totsuka Yukari; Kawahara Nobuo; Yajima Hirofumi; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2009

P-009(O-1) Genotoxicity of derivative of amino benzoazepinoquinolinone in the Maillard reaction(Genotoxicity,Poster Session)
Kobayashi Sae; Nishizaki Marina; Ozeki Minoru; Kajimoto Tetsuya; Node Manabu; Hasei Tomohiro; Watanabe Tetsushi; Totsuka Yukari; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2009

P-043 DNA-damaging capability of ultrafine particles(DNA damages,Poster Session)
Ogo Sayaka; Kawanishi Masanobu; Totsuka Yukari; Wakabayashi Keiji; Yagi Takashi
日本環境変異原学会大会プログラム・要旨集, 2009

Mutagenic Specificity of N-Nitrosotaurocholic Acid in supF Shuttle Vector Plasmids
Masanobu Kawanishi; Hiroshi Nishida; Yukari Totsuka; Koichi Nishimura; Keiji Wakabayashi; Takashi Yagi
Genes and Environment, 2009, Not refereed, Not invited

Analysis of DNA adducts in the lung of mice exposed to multi-wall carbon nanotube (MWCNT).
MATSUDA TOMONARI; NISHI RYUHEI; TOTSUKA YUKARI; WAKABAYASHI KEIJI
日本内分泌かく乱化学物質学会研究発表会要旨集, 13 Dec. 2008, Not refereed, Not invited

多層カーボンナノチューブを曝露したマウス肺におけるDNA付加体の解析
NISHI RYUHEI; TOTSUKA YUKARI; WAKABAYASHI KEIJI; MATSUDA TOMONARI
日本環境変異原学会大会プログラム・要旨集, 20 Nov. 2008, Not refereed, Not invited

P-071 Genotoxicity of nanoparticles in in vivo assay systems(Poster Session)
Totsuka Yukari; Kato Tatsuya; Masuda Shuichi; Nohmi Takehiko; Sugimura Takashi; Wakabayashi Keiji
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 20 Nov. 2008, Not refereed, Not invited

P-126 Mutagenicity of extract prepared from surface soil of residential and industrial areas in Shizuoka prefecture, and detection of mutagens(Poster Session)
KATO Tatsuya; MASUDA Shuichi; WATANABE Tetsushi; TOTSUKA Yukari; WAKABAYASHI Keiji; KINAE Naohide
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 20 Nov. 2008, Not refereed, Not invited

D317 モンシロチョウ由来アポトーシス誘導タンパク質ピエリシン-1の寄生蜂に対する毒性
高橋(中口) 梓; 松本 恭子; 山本 真史; 岩淵 喜久男; 戸塚 ゆ加里; 杉村 隆; 若林 敬二
日本応用動物昆虫学会大会講演要旨, 12 Mar. 2008

P-003 Formation of aminophenylnorharman-phosphoester (APNH-PE) adducts(Poster Session)
Nishimura Koichi; Totsuka Yukari; Kirigaya Hidemasa; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2008

P-059 Genotoxicity of nanomaterials(Poster Session)
OGO Sayaka; KAWANISHI Masanobu; TOTSUKA Yukari; WAKABAYASHI Keiji; YAGI Takashi
日本環境変異原学会大会プログラム・要旨集, 2008

P-004 Formation of an RNA adduct derived from aminophenylnorharman (APNH), a novel endogenous mutagen and carcinogen(Poster Session)
Higuchi Takashi; Totsuka Yukari; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2008

P-053 Mutagenicity of PBTA-6 and benzo[a]pyrene in the gill and hepatopancreas of rpsL transgenic zebrafish(Poster Session)
Amanuma Kimiko; Tone Suguru; Nagaya Masato; Matsumoto Michi; Watanabe Tetsushi; Totsuka Yukari; Wakabayashi Keiji; Aoki Yasunobu
日本環境変異原学会大会プログラム・要旨集, 2008

Analysis of DNA adducts derived from N-nitroso bile acid conjugates in rat duodenogastric reflux model.
NISHIMURA KOICHI; TOTSUKA YUKARI; TERASAKI MASARU; MUKAISYO KEN-ICHI; HATTORI TAKANORI; MATSUDA TOMONARI; SUGIMURA TAKASHI; WAKABAYASHI KEIJI
日本環境変異原学会大会プログラム・要旨集, 10 Nov. 2007, Not refereed, Not invited

Formation of DNA adducts derived from N-nitroso bile acid comjugates in rat duodenogastric reflux model.
NISHIMURA KOICHI; TOTSUKA YUKARI; TERASAKI MASARU; MUKAISYO KEN-ICHI; HATTORI TAKANORI; TAKAMURA TAKEJI; MATSUDA TOMONARI; SUGIMURA TAKASHI; WAKABAYASHI KEIJI
日本癌学会学術総会記事, 25 Aug. 2007, Not refereed, Not invited

P028 Mutations produced by N-nitrosotaurocholic acid in the supF target gene replicated in human cells
NISHIDA Hiroshi; KAWANISHI Masanobu; TOTSUKA Yukari; WAKABAYASHI Keiji; YAGI Takashi
日本環境変異原学会大会プログラム・要旨集, 2007

P003 Analysis of aminophenylnorharman (APNH) in human hair samples
IKEDA Megumi; TOTSUKA Yukari; NISHIGAKI Rena; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2007

O-12 Analysis of the Major RNA Adduct Derived from Aminophenylnorharman, a Novel Endogenous Mutagen and Carcinogen(ACEM Oral Presentation III)
TOTSUKA Yukari; NISHIGAKI Rena; TAKAMURA Takeji; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2007

P034 Analysis of the Major RNA Adduct Derived from Aminophenylnorharman, a Novel Endogenous Mutagen and Carcinogen
TOTSUKA Yukari; NISHIGAKI Rena; TAKAMURA Takeji; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2007

W3-2 Evaluation of mutagenic activity of PBTA-6 using fish and rat(Workshop(3) : Mutagens and their Action Mechanisms)
Deguchi Yuya; Toyoizumi Tomoyasu; Masuda Shuichi; Amanuma Kimiko; Aoki Yasunobu; Watanabe Tetsushi; Totsuka Yukari; Wakabayashi Keiji; Kinae Naohide
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 10 Nov. 2006, Not refereed, Not invited

P110 Evaluation of mutagenic activity of PBTA-6 using fish and rat(Poster Session)
Deguchi Yuya; Toyoizumi Tomoyasu; Masuda Shuichi; Amanuma kimiko; Aoki Yasunobu; Watanabe Tetsushi; Totsuka Yukari; Wakabayashi Keiji; Kinae Naohide
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan, 10 Nov. 2006, Not refereed, Not invited

Genotoxic activation of N-hydroxyaminophenylnorharman by human sulfotransferases expressing in Salmonella Typhimurium umn tester strains.
Y. Oda; Y. Totsuka; K. Wakabayashi
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Jul. 2006, Not refereed, Not invited

P023 Structural analysis of DNA adducts formed from taurine with nitrite(Poster Session)
Terasaki Masaru; Totsuka Yukari; Kawahara Nobuo; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2006

P030 Analysis of aminophenylnorharman (APNH) in human hair samples(Poster Session)
Nishigaki Rena; Totsuka Yukari; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2006

W1-1 Development of a sensitive method for detection of k-ras mutations(Workshop(1) : New Test Methods for Biological Effects)
Totsuka Yukari; Nishigaki Rena; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2006

P022 Development of a sensitive method for detection of k-ras mutations(Poster Session)
Totsuka Yukari; Nishigaki Rena; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2006

P-87 Analysis of N-nitroso-bis(2-oxopropyl)amine (BOP) and its metabolites in pancreatic juice of Syrian golden hamsters treated with BOP(Poster Presentations(2))
Nishigaki R; Totsuka Y; Mori Y; Masumura K; Nohmi T; Sugimura T; Wakabayashi K
日本環境変異原学会大会プログラム・要旨集, 2005

P-10 Clastogenicity and mutational specificity of a N-hydroxy metabolite of aminophenylnorharman(Poster Presentations(1))
Ohe T.; Mizuno T.; Totsuka Y.; Takamura T.; Oda Y.; Wakabayashi K.
日本環境変異原学会大会プログラム・要旨集, 2005

P-33 Structural analysis of DNA adducts formed from N-nitrosotaurocholic acid (NO-TCA)(Poster Presentations(1))
Totsuka Y; Nishigaki R; Enomoto S; Takamura-Enya T; Masumura K; Nohmi T; Sugimura T; Wakabayashi K
日本環境変異原学会大会プログラム・要旨集, 2005

O2-4 Detection of aminophenylnorharman (APNH) in human urine
Nishigaki Rena; Totsuka Yukari; Kataoka Hiroyuki; Sugimura Takashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2004

P2-061 Quantitative mutational analysis of k-ras gene
Totsuka Yukari; Sugimura Takahashi; Wakabayashi Keiji
日本環境変異原学会大会プログラム・要旨集, 2004

P1-026 Translesion DNA synthesis of mono ADP-ribosylated dG by Y-family DNA polymerases
Kawanishi Masanobu; Matsukawa Kazuki; Takamura Takeji; Ohashi Eiji; Totsuka Yukari; Watanabe Masahiko; Sugimura Takashi; Hanaoka Fumio; Ohmori Haruo; Wakabayashi Keiji; Yagi Takashi
日本環境変異原学会大会プログラム・要旨集, 2004

発癌物質を投与した動物におけるすい液の変異原性
岡保夫; 三井雅之; 北橋宗; 戸塚ゆ加里; 増村健一; 森幸雄; 山田雅巳; 能美健彦; 若林敬二
日本癌学会総会記事, 2004

Clastogenicity and mutational specificity of an N-hydroxy metabolite of aminophenylnorharman.
T Ohe; T Mizuno; Y Totsuka; T Takamura; Y Oda; K Wakabayashi
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2004, Not refereed, Not invited

ハムスターにおけるすい液を介するすい管癌発生機構の解析:すい液によるニトロソ化合物の活性化
岡保夫; 戸塚ゆ加里; 増村健一; 森幸雄; 辻内俊文; 国安弘基; 山田雅巳; 能美健彦; 若林敬二
日本癌学会総会記事, 2003

Genotoxicity and mutational specificity induced by aminophenylnorharman and related heterocyclic amines.(GENERAL SESSION BY ORAL PRESENTATION)(GENOTOXICITY)
ODA YOSHIMITSU; SHIMADA TSUTOMU; TOTSUKA YUKARI; WAKABAYASHI KEIJI; OHE TAKESHI
Journal of toxicological sciences, Oct. 2002

Mutatiinal analysis of mono(ADP-ribosyl)ated DNA in CHL cells treated with pieisin-I
TOTSUKA Yukari; NISHIGAKI Rena; WATANABE Masahiko; TAKAMURA Takeji; KAWANISHI Masanobu; MATSUKAWA Kazuki; YAGI Takashi; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2002

Molecular analysis of mutations induced by pierisin, apotosis-inducing protein deriverd from Pieris butterflis.
MATSUKAWA Kazuki; KAWANISHI Masanobu; TAKAMURA ENYA Takeji; TOTSUKA Yukari; SUGIMURA Takashi; WAKABAYASHI Keiji; YAGI Takashi
日本環境変異原学会大会プログラム・要旨集, 2002

Identification of the enzymes involved in the formation of APNH from norharman with aniline
NISHIGAKI Rena; TOTSUKA Yukari; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2002

Mono(ADP-ribosyl)ation of guanine base by pierisinl, an apoptosis-inducing protein from cabbagebutterfly.
TAKAMURA Takeji; WATANABE Masahiko; TOTSUKA Yukari; KANAZAWA Takeshi; HIBIYA Yuko; KOYAMA Koutaro; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2002

Formation of DNA adducts in various organs of F344 rats given APNH.
TOTSUKA Yukari; KAWAMORI Toshihiko; TAKAHASHI Mami; MUTO Michihiro; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2000

Analysis of estorgen-like compounds in food
TAKAMURA-ENYA Takeji; ISHIHARA Jyunko; TOTSUKA Yukari; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2000

Mechanisms on metabolic activation of genotoxic aminophenylnorharman and aminomethylphenylphenylnorharman
ODA Yoshimitsu; SHIMADA Tsutomu; TOTSUKA Yukari; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 2000

21WA-03-3 In Vivo Toxicity of Aminophenylnorharman, a Product from the Reaction of Norharman and Aniline, in F344 Rats.
TOTSUKA Yukari; KAWAMORI Toshihiko; ISHIHARA Junko; MITSUMORI Kunitoshi; HISADA Shigeru; SUGIMURA Takashi; WAKABAYASHI Keiji
Journal of toxicological sciences, 26 Oct. 1999

DNA adduct formation of aminophenylnorharman, responsible for co-mutagenic action of norharman
TOTSUKA Yukari; ENYA Takeji; ISHIHARA Junko; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 1999

Search for estrogen-like compounds present in food
ISHIHARA Junko; ENYA Takeji; TOTSUKA Yukari; SUGIMURA Takashi; WAKABAYASHI Keiji
日本環境変異原学会大会プログラム・要旨集, 1999

P-83 Aminophenylnorharmanのラットに対する毒性
戸塚 ゆ加里; 川森 俊人; 石原 純子; 三森 国敏; 久田 茂; 杉村 隆; 若林 敬二
日本環境変異原学会大会プログラム・要旨集, 1998

★
01 Nov. 2021, Not invited

★Multidisciplinary Study to Adress the Causal Relationship between NPIP Exposure and Esophageal Cancer.
Yukari Totsuka
The 4th International Forum on Theory and Practice of Cancer Prevention and Control, 30 Oct. 2021, Invited

★
30 Sep. 2021, Not invited

★
26 Mar. 2021, Invited

★
01 Nov. 2021, Not invited

★Multidisciplinary Study to Adress the Causal Relationship between NPIP Exposure and Esophageal Cancer.
Yukari Totsuka
The 4th International Forum on Theory and Practice of Cancer Prevention and Control, 30 Oct. 2021, Invited

★
30 Sep. 2021, Not invited

★
26 Mar. 2021, Invited

★
01 Nov. 2021, Not invited

★Multidisciplinary Study to Adress the Causal Relationship between NPIP Exposure and Esophageal Cancer.
Yukari Totsuka
The 4th International Forum on Theory and Practice of Cancer Prevention and Control, 30 Oct. 2021, Invited

★
30 Sep. 2021, Not invited

★
26 Mar. 2021, Invited

Colitis-associated cancer に寄与するメチルアミンクロラミン類由来の変異原性物質の解明
渡部 浩平; 下田 康代; 小宮 雅美; 戸塚 ゆ加里; 加藤 孝一
日本薬学会144年会大会, Mar. 2024, Not invited

マウス肝臓由来オルガノイドを用いた新規毒性試験法の開発
宮崎 飛翔; 藤岡 正喜; 鰐渕 英樹; 美谷島 克弘; 石ケ守 里加子; 永井 桃子; 加藤 孝一; 戸塚 ゆ加里
日本薬学会144年会大会, Mar. 2024, Not invited

生体を模倣したin vitro遺伝毒性評価
戸塚ゆ加里
日本薬学会144年会シンポジウム, Mar. 2024, Invited

役に立つがんの基本講座 〜がんの要因から予防まで〜
戸塚ゆ加里
日本大学薬学部地域貢献プロジェクト, Feb. 2024, Invited

ナノマテリアルの遺伝毒性評価とそのメカニズムの解析
戸塚ゆ加里
日本酸化ストレス学会, Dec. 2023, Invited

Elucidation of driver adducts of cancer development using comprehensive analysis of DNA adducts
Yukari Totsuka
The 51st International Symposium of the Princess Takamatsu Cancer Research Fund, Nov. 2023, Invited

アルコール発がんにおけるドライバーアダクトの探索と変異誘発メカニズムの解明
本橋実奈; 別役雄毅; 高村岳樹; 小宮雅美; 佐々彰; 戸塚ゆ加里
第52回環境変異原学会, Nov. 2023, Not invited

職業性胆管がん原因物質であるハロゲン系炭化水素のドライバーアダクト探索
白鳥修平; 小宮雅美; 魏民; 鈴木周五; 鰐渕英機; Jiri Zavadil; 渡部浩平; 戸塚ゆ加里
第52回環境変異原学会, Nov. 2023, Not invited

メチルアミン・ジクロラミン由来の大腸炎関連発がんメカニズムの解明
Kohei Watanabe; Yasuyo Shimoda; Masami Sakano; Yukari Totsuka; Koichi Kato
第52回環境変異原学会, Nov. 2023, Not invited

アドバンストナノマテリアルのin vitro遺伝毒性評価
石ケ守 里加子; 澤田 琉那; 前嶋 愛美; 小宮雅美; 大野彰子; 戸塚ゆ加里
第52回環境変異原学会, Nov. 2023, Not invited

加熱式タバコの遺伝毒性評価
小宮 雅美; 広田 航太郎; 山口 大雅; 石ケ守 里加子; 稲葉 洋平; 戸塚 ゆ加里
第52回環境変異原学会, Nov. 2023, Not invited

Elucidating the Relationship between Environmental Factors and Human Cancer Development Using Next Generation Sequencers
Yukari Totsuka; Masami Komiya; Tomonari Matsuda; Mamoru Kato
82nd 日本癌学会学術総会, Oct. 2023, Not invited

Prospects for DNA adductomics analysis
YukarinTotsuka
54th EMGS, Sep. 2023, Invited

加熱式タバコの遺伝毒性評価
小宮 雅美; 広田 航太郎; 山口 大雅; 石ケ守 里加子; 稲葉 洋平; 戸塚 ゆ加里
がん予防学術大会2023, Sep. 2023, Not invited

Comprehensive analyses of genome and DNA adducts elucidate association between environmental factors and human cancer development
Yukari Totsuka
12th AACR-JCA Joint Conference, Dec. 2022, Invited

集学的アプローチによるがんの要因解明と予防研究への展望
戸塚ゆ加里; 小宮雅美; 永井桃子; 加藤 護; 松田知成
第35回 発癌病理研究会, Nov. 2022, Invited

職業性膀胱がん候補化学物質によるDNA付加体の網羅的解析
帯金明日香; 小宮雅美; 鈴木 周五; 魏民; 鰐渕 英機; 戸塚 ゆ加里
第51回 環境変異原学会, Nov. 2022, Not invited

DNA鎖間架橋修復欠損細胞を用いたコリバクチン産生大腸菌の細胞毒性と遺伝毒性の評価
坪井理; 植嶋亜衣; 久富優太; 小田美光; 恒松雄太; 佐藤道大; 平山裕一郎; 三好規之; 岩下雄二; 吉川悠子; 椙村春彦; 戸塚ゆ加里; 若林敬二; 渡辺賢二; 川西優喜
第51回 環境変異原学会, Nov. 2022, Not invited

集学的アプローチによるがんの要因解明と予防研究への展望
戸塚ゆ加里
第1回包括的がん緩和病態生理医療薬学研究会, Nov. 2022, Invited

Comprehensive analysis of DNA adducts formed from candidate chemicals for occupational bladder cancer
帯金明日香; 小宮雅美; 鈴木 周五; 魏民; 鰐渕 英機
第81回癌学会, Sep. 2022, Not invited

Establishment of novel genotoxicity assay system using organoids derived from murine normal epithelial tissues
小宮雅美; 落合雅子; 今井俊夫; 戸塚ゆ加里
第81回癌学会, Sep. 2022, Not invited

Next generation sequencing technology elucidates the association between environmental factors and human cancer development
戸塚ゆ加里; 小宮雅美; 松田知成; 加藤護
第81回癌学会, Sep. 2022, Not invited

In vitro metabolic dynamics for p-semidine-type homo- and hetero-dimerization of monocyclic aromatic amines
Kobayashi T; Yoshioka Y; Kishimoto S; Watanabe K; Totsuka Y; Wakabayashi K; Miyoshi N
13th ICEM, Aug. 2022, Not invited

New horizons of DNA adductome for exploring environmental causes of cancer
Yukari Totsuka
13th ICEM, Aug. 2022, Invited

細胞毒性を有するo-Toluidineとo-Anisidineの尿中代謝物はラット膀胱上皮でALDH1A1を誘導する
小林 琢磨; 豊田 武士; 吉岡 泰淳; 岸本 真治; 松下 幸平; 赤根 弘敏; 小川 久美子; 渡辺 賢二; 高村 岳樹; 戸塚 ゆ加里; 若林 敬二; 三好 規之
第29回日本がん予防学術大会, Jul. 2022, Not invited

芳香族アミンの膀胱がんメカニズムの解析
小宮 雅美; 鈴木 周五; 魏民; 鰐渕 英機; 戸塚 ゆ加里
第29回日本がん予防学術大会, Jul. 2022, Not invited

集学的アプローチによる化学物質の遺伝毒性評価の現状と将来展望
戸塚ゆ加里
第49回日本毒性学会, Jun. 2022, Invited

ナノマテリアルに特化した新規in vitro生体模倣評価系の開発
戸塚ゆ加里
日本薬学会 第142年会, Mar. 2022, Invited

ゲノムおよびDNA付加体の網羅的解析により環境因子とがん発生との関連を解明する
戸塚ゆ加里
第95回 日本薬理学会, Mar. 2022, Invited

05 Jun. 2021, Invited

23 May 2021, Invited

07 Mar. 2021, Invited

05 Jun. 2021, Invited

23 May 2021, Invited

07 Mar. 2021, Invited

05 Jun. 2021, Invited

23 May 2021, Invited

07 Mar. 2021, Invited

Development of a method to identify single molecule adducts generated on genomic DNA
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2015 - 31 Mar. 2018
Shiizaki Kazuhiro; TOTSUKA Yukari

Exploration of esophageal cancer etiology using comprehensive DNA adduct analysis (DNA adductome analysis)
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2013 - 31 Mar. 2016
Totsuka Yukari; Lin Yingsong

Identification and risk assessment of novel mutagens isolated from diabetes model
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2009 - 2011
WATANABE Tetsushi; HASEI Tomohiro; OZEKI Minoru; TOTSUKA Yukari