博士（情報学）, 京都大学

Young Scientists Award / JSAS Excellent Presentation Award
Analysis of realized heritability and other genetic parameters in a long-term selection experiment for non-destructive deformation in White Leghorns, 国際学会・会議・シンポジウム等の賞

★Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population
Olivier Gervais; Kazuko Ueno; Yosuke Kawai; Yuki Hitomi; Yoshihiro Aiba; Mayumi Ueta; Minoru Nakamura; Katsushi Tokunaga; Masao Nagasaki
European Journal of Human Genetics, 2021年04月, 査読有り, 通常論文
筆頭著者

★Genomic Heritabilities and Correlations of 17 Traits Related to Obesity and Associated Conditions in the Japanese Population
Olivier Gervais; Kazuko Ueno; Yosuke Kawai; Yuki Hitomi; Kazuharu Misawa; Shunsuke Teraguchi; Yen-Yen Wang; Katsushi Tokunaga; Masao Nagasaki
G3: Genes, Genomes, Genetics, 2020年07月, 査読有り, 通常論文
筆頭著者

★Antagonistic genetic correlations for milking traits within the genome of dairy cattle
Olivier Gervais; Ricardo Pong-Wong; Pau Navarro; Chris S. Haley; Yoshitaka Nagamine
PLoS ONE, 2017年04月, 査読有り, 通常論文
筆頭著者

rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis
Yuki Hitomi; Yoshihiro Aiba; Kazuko Ueno; Nao Nishida; Yosuke Kawai; Minae Kawashima; Michio Yasunami; Olivier Gervais; Masahiro Ito; Heather J. Cordell; George F. Mells; Masao Nagasaki; Katsushi Tokunaga; Makoto Tsuiji; Minoru Nakamura
Journal of Autoimmunity, 2022年01月, 査読有り

An international genome-wide meta-analysis of primary biliary cholangitis: novel risk loci and candidate drugs
Heather J. Cordell; James J. Fryett; Kazuko Ueno; Rebecca Darlay; Yoshihiro Aiba; Yuki Hitomi; Minae Kawashima; Nao Nishida; Seik-Soon Khor; Olivier Gervais; Yosuke Kawai; Masao Nagasaki; Katsushi Tokunaga; Ruqi Tang; Yongyong Shi; Zhiqiang Li; Brian D. Juran; Elizabeth J. Atkinson; Alessio Gerussi; Marco Carbone; Rosanna Asselta; Angela Cheung; Mariza de Andrade; Aris Baras; Julie Horowitz; Manuel A.R. Ferreira; Dylan Sun; David E. Jones; Steven Flack; Ann Spicer; Victoria L. Mulcahy; Jinyoung Byan; Younghun Han; Richard N. Sandford; Konstantinos N. Lazaridis; Christopher I. Amos; Gideon M. Hirschfield; Michael F. Seldin; Pietro Invernizzi; Katherine A. Siminovitch; Xiong Ma; Minoru Nakamura; and George F. Mells for the Canadian PBC Consortium; Chinese PBC Consortium; Italian PBC Study Group; Japan-PBC-GWAS Consortium; US PBC Consortium; and UK-PBC Consortium
Journal of Hepatology, 2021年05月, 査読有り, 通常論文

X chromosome contribution to the genetic architecture of primary biliary cholangitis
Rosanna Asselta; Elvezia Maria Paraboschi; Alessio Gerussi; Heather J. Cordell; George F. Mells; Richard N. Sandford; David E. Jones; Minoru Nakamura; Kazuko Ueno; Yuki Hitomi; Minae Kawashima; Nao Nishida; Katsushi Tokunaga; Masao Nagasaki; Atsushi Tanaka; Ruqi Tang; Zhiqiang Li; Yongyong Shi; Xiangdong Liu; Ma Xiong; Gideon Hirschfield; Katherine A. Siminovitch; Canadian-US PBC Consortium; Italian PBC Genetics Study Group; UK-PBC Consortium; Japan PBC-GWAS Consortium; Marco Carbone; Giulia Cardamone; Stefano Duga; M. Eric Gershwin; Michael F. Seldin; Pietro Invernizzi
Gastroenterology, 2021年03月, 査読有り, 通常論文

rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis
Yuki Hitomi; Yoshihiro Aiba; Yosuke Kawai; Kaname Kojima; Kazuko Ueno; Nao Nishida; Minae Kawashima; Olivier Gervais; Seik-Soon Khor; Masao Nagasaki; Katsushi Tokunaga; Minoru Nakamura & Makoto Tsuiji
Scientific Reports, 2021年02月, 査読有り, 通常論文

Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis
Kazuko Ueno; Yoshihiro Aiba; Yuki Hitomi; Shinji Shimoda; Hitomi Nakamura; Olivier Gervais; Yosuke Kawai; Minae Kawashima; Nao Nishida; Seik‐Soon Kohn; Kaname Kojima; Shinji Katsushima; Atsushi Naganuma; Kazuhiro Sugi; Tatsuji Komatsu; Tomohiko Mannami; Kouki Matsushita; Kaname Yoshizawa; Fujio Makita; Toshiki Nikami; Hideo Nishimura; Hiroshi Kouno; Hirotaka Kouno; Hajime Ohta; Takuya Komura; Satoru Tsuruta; Kazuhiko Yamauchi; Tatsuro Kobata; Amane Kitasato; Tamotsu Kuroki; Seigo Abiru; Shinya Nagaoka; Atsumasa Komori; Hiroshi Yatsuhashi; Kiyoshi Migita; Hiromasa Ohira; Atsushi Tanaka; Hajime Takikawa; Masao Nagasaki; Katsushi Tokunaga; Minoru Nakamura; PBC‐GWAS Consortium in Japan
Hepatology Communications, 2020年03月, 査読有り, 通常論文

HLA-VBSeq v2: improved HLA calling accuracy with full-length Japanese class-I panel
Yen-Yen Wang; Takahiro Mimori; Seik-Soon Khor; Olivier Gervais; Yosuke Kawai; Yuki Hitomi; Katsushi Tokunaga; Masao Nagasaki
Human Genome Variation, 2019年06月, 査読有り, 通常論文

Population-scale whole genome sequencing identifies 271 highly polymorphic short tandem repeats from Japanese population
Satoshi Hirata; Kaname Kojima; Kazuharu Misawa; Olivier Gervais; Yosuke Kawai; Masao Nagasaki
Heliyon, 2018年08月, 査読有り, 通常論文

Long‐term selection using a single trait criterion, non‐destructive deformation, in White Leghorns: Effect over time on genetic parameters for traits related to egg production
Olivier Gervais; Keijiro Nirasawa; Christian E. Vincenot; Yoshitaka Nagamine; Kazuyuki Moriya
Animal Science Journal, 2016年06月, 査読有り, 通常論文
筆頭著者

Effect of Long-Term Selection for Non-Destructive Deformation on Egg Shape in White Leghorns
Olivier Gervais; Keijiro Nirasawa; Christian E. Vincenot; Yoshitaka Nagamine; Kazuyuki Moriya
The Journal of Poultry Science, 2016年05月, 査読有り, 通常論文
筆頭著者

Multiple-trait analysis of a long-term selection experiment for non-destructive deformation in White Leghorns: Evolution of genetic parameters for traits related to eggshell strength
Olivier Gervais; Keijiro Nirasawa; Christian E. Vincenot; Yoshitaka Nagamine; Kazuyuki Moriya
Livestock Science, 2016年05月, 査読有り, 通常論文
筆頭著者

遺伝子医学36号,特集：Common disease解析の最前線
分担執筆, ポリジェニックモデルによるゲノム情報解析の最前線
メディカルドゥ, 2021年04月
9784909508126

rs1944919 on human chromosome 11q23.1 and its effector genes COLCA1 and COLCA2 confer susceptibility to primary biliary cholangitis
Y. Hitomi; Y. Aiba; Y. Kawai; K. Kojima; K. Ueno; N. Nishida; M. Kawashima; O. Gervais; S-S. Khor; M. Nagasaki; K. Tokunaga; M. Nakamura; M. Tsuiji
2021 Annual Meeting of the American Society of Human Genetics, 2021年10月, 通常論文

Applying the regional heritability mapping method to primary biliary cholangitis in the Japanese population
O. Gervais; K. Ueno; Y. Kawai; Y. Hitomi; Y. Aiba; M. Ueta; M. Nakamura; K. Tokunaga; M. Nagasaki
2021 Annual Meeting of the American Society of Human Genetics, 2021年10月, 通常論文

Identification of seven primary functional variants in primary biliary cholangitis susceptibility loci in the Japanese population
Y. Hitomi; Y. Aiba; K. Ueno; Y. Kawai; N. Nishida; M. Kawashima; O. Gervais; M. Nagasaki; K. Tokunaga; M. Tsuiji; M. Nakamura
2021 American Society for Histocompatibility and Immunogenetics Annual Meeting, 2021年09月, 通常論文

COLCA1/COLCA2, the effector genes in primary biliary cholangitis susceptibility locus chromosome 11q23.1
Y. Hitomi; Y. Aiba; Y. Kawai; K. Kojima; K. Ueno; N. Nishida; M. Kawashima; O. Gervais; S-S. Khor; M. Nagasaki; K. Tokunaga; M. Nakamura; M. Tsuiji
Japan Society of Human Genetics 65rd Annual Meeting, 2020年11月

The analysis of POU2AF1 and its related molecules in the pathogenesis of primary biliary cholangitis by using GWAS and transcriptome datasets
Y. Aiba; K. Ueno; Y. Hitomi; O. Gervais; Y. Kawai; M. Kawashima; N. Nishida; A. Komori; K. Kojima; M. Nagasaki; K. Tokunaga; M. Nakamura
2020 Annual Meeting of the American Society of Human Genetics, 2020年10月

Transcriptome and GWAS identified androgen receptor as a central regulator for eosinophilia in primary biliary cholangitis
K. Ueno; Y. Aiba; Y. Hitomi; Y. Kawai; S.-S. Khor; O. Gervais; M. Kawashima; N. Nishida; K. Kojima; M. Nagasaki; K. Tokunaga; M. Nakamura
2020 Annual Meeting of the American Society of Human Genetics, 2020年10月

Genome-wide mapping of 4,483 plasma protein QTLs of the 743 Japanese population
M. Nagasaki; K. Nochioka; O. Gervais; K. Ueno; Y. Kawai; K. Tokunaga; T. Shiroto; S. Yasuhiko
2020 Annual Meeting of the American Society of Human Genetics, 2020年10月

Heritability of traits related to metabolic syndrome and chronic kidney disease in a large-scale cohort from Northeast Japan
O. Gervais; Y. Kawai; S-S. Khor; K. Ueno; Y. Hitomi; Y-Y. Wang; K. Tokunaga; M. Nagasaki
A Century of Genetics, 2019年11月, 通常論文

Application of genome-editing to elucidate pathogenesis attributed to primary biliary cholangitis
Y. Hitomi; Y. Kawai; K. Ueno; N. Nishida; M. Kawashima; Y. Aiba; O. Gervais; S-S. Khor; M. Tsuiji; M. Nagasaki; M. Nakamura; K. Tokunaga
Japan Society of Human Genetics 64rd Annual Meeting, 2019年11月

Linear mixed model analysis of Cystatin C in the Japanese population
O. Gervais; Y. Kawai; S-S. Khor; K. Ueno; Y. Hitomi; Y-Y. Wang; K. Tokunaga; M. Nagasaki
Japan Society of Human Genetics 64rd Annual Meeting, 2019年11月, 通常論文

Towards HLA-VBSeq v3: An HLA calling package for HLA class I and II
M. Nagasaki; Y-Y. Wang; S-S. Khor; O. Gervais; Y. Kawai; Y. Hitomi; K. Tokunaga
2019 Annual Meeting of the American Society of Human Genetics, 2019年10月

Triglyceride concentration in the Japanese population: A polygenic model analysis
O. Gervais; Y. Kawai; S-S. Khor; K. Ueno; Y. Hitomi; Y-Y. Wang; K. Tokunaga; M. Nagasaki
2019 Annual Meeting of the American Society of Human Genetics, 2019年10月, 通常論文

Integrated analysis of GWAS and mRNA expression array identified IFNG and CD40L as the most significant upstream-regulators in primary biliary cholangitis
K. Ueno; Y. Aiba; Y. Hitomi; S. Shimoda; O. Gervais; Y. Kawai; M. Kawashima; N. Nishida; K. Kojima; M. Nagasaki; K. Tokunaga; M. Nakamura
2019 Annual Meeting of the American Society of Human Genetics, 2019年10月

HLA-VBSeq v2: enhancements of HLA calling accuracy from WGS data with full-length Japanese HLA sequences
Y-Y. Wang; T. Mimori; S-S. Khor; O. Gervais; Y. Kawai; Y. Hitomi; K. Tokunaga; M. Nagasaki
European Human Genetics Conference 2019, 2019年06月

A massive collection of Japanese full-length class-I HLA sequences enhanced the accuracy of HLA genotyping from WGS data
Y-Y. Wang; T. Mimori; S-S. Khor; Y. Hitomi; O. Gervais; K. Misawa; Y. Kawai; K. Tokunaga; M. Nagasaki
2018 International Conference for Leading and Young Medical Scientists, 2018年12月

Pathway analysis using datasets of GWAS and mRNA expression array identified IFNG as the most significant upstream regulator in primary biliary cholangitis in the Japanese population
K. Ueno; Y. Aiba; O. Gervais; Y. Kawai; Y. Hitomi; K. Kojima; M. Kawashima; N. Nishida; S. Shimoda; M. Nagasaki; K. Tokunaga; M. Nakamura
2018 Annual Meeting of the American Society of Human Genetics, 2018年10月

Unifying copy number variant calling and imputation from SNP arrays
T. Mimori; K. Ueno; S-S. Khor; Y. Hitomi; O. Gervais; K. Tokunaga; M. Nagasaki
2018 Annual Meeting of the American Society of Human Genetics, 2018年10月

Short-tandem repeat（STR) profile of pentanucleotide repeats and high-resolution STR typing solution for the Japanese population
M. Saito; K. Kojima; K. Misawa; T. Mimori; O. Gervais; Y. Kawai; Y. Hitomi; K. Tokunaga; M. Nakamura; M. Nagasaki
2018 Annual Meeting of the American Society of Human Genetics, 2018年10月

A massive collection of Japanese full-length class-I HLA sequences enhanced the accuracy of HLA typing from WGS data
Y-Y. Wang; T. Mimori; S-S. Khor; Y. Hitomi; O. Gervais; K. Misawa; Y. Kawai; K. Tokunaga; M. Nakamura; M. Nagasaki
2018 Annual Meeting of the American Society of Human Genetics, 2018年10月

Regional heritability mapping analysis of Waist Circumference in a Japanese population
O. Gervais; K. Misawa; Y. Harada; T. Mimori; Y. Kawai; K. Tokunaga; M. Nagasaki
2018 Annual Meeting of the American Society of Human Genetics, 2018年10月, 通常論文

The genetics of obesity: Polygenic model analysis of Waist-to-Height ratio in a Japanese population
O. Gervais; K. Misawa; Y. Harada; T. Mimori; Y. Kawai; K. Tokunaga; M. Nagasaki
Japan Society of Human Genetics 63rd Annual Meeting, 2018年10月, 通常論文

A genome-wide association study based on data from the Tohoku Medical Megabank cohort study identifies a novel susceptibility locus for total IgE in Japanese population
K. Shido; K. Kojima; K. Yamasaki; O. Gervais; Y-Y. Wang; M. Nagasaki; S. Aiba
International Investigative Dermatology 2018, 2018年05月

GWAS polygenic model approach applied to Primary Biliary Cholangitis (PBC) in a Japanese population
O. Gervais; K. Ueno; K. Kojima; Y. Aiba; M. Kawashima; Y. Kawai; Y. Hitomi; K. Tokunaga; M. Nakamura; M. Nagasaki
2017 Annual Meeting of the American Society of Human Genetics, 2017年10月, 通常論文

Analysis of realized heritability and other genetic parameters in a long-term selection experiment for non-destructive deformation in White Leghorns
O. Gervais; K. Nirasawa; C. Vincenot; Y. Nagamine; K. Moriya
17th AAAP Animal Science Congress, 2016年08月, 通常論文

ポリジェニックモデルによる慢性腎臓病・メタボリックシンドローム関連形質ゲノム解析
2018年04月 - 2020年03月