O'Hashi Kazunori

School of Dentistry Department of DentistryAssistant Professor

Researcher Information

Research Keyword

  • 海馬
  • 機械学習
  • 二光子レーザー走査型顕微鏡
  • 広域カルシウムイメージング
  • 大脳皮質
  • 自発活動
  • 痛覚変調性疼痛
  • 大うつ病障害
  • 島皮質
  • 経頭蓋直流電気刺激法
  • 内側前頭前野
  • 血液脳関門
  • 数理モデリング
  • 電位感受性色素イメージング

Career

  • Apr. 2026 - Present
    Kobe University, Graduate School of Medicine, researcher
  • Apr. 2026 - Present
    Kyoto Institute of Technology, Faculty of Applied Biology, Project Senior Lecturer
  • 2020 - 2026
    日本大学, 助教
  • 2016 - 2020
    国立精神神経医療研究センター, 流動研究員
  • 2011 - 2016
    理化学研究所脳科学総合研究センター, 研究員
  • 2007 - 2011
    Weizmann Institute of Science, Postdoctoral fellow
  • 2007 - 2007
    理化学研究所脳科学総合研究センター, 特任研究員
  • 2004 - 2007
    理化学研究所脳科学総合研究センター, Junior Research Associate
Research activity information

Award

  • 2023
    日本歯科薬物療法会, 学術奨励賞
    大橋一徳

Paper

  • ★Repetitive nociceptive stimulation increases spontaneous neural activation similar to nociception-induced activity in mouse insular cortex
    Shutaro Kobayashi; Kazunori O'Hashi; Masayuki Kobayashi
    Scientific Reports, Sep. 2022, Refereed
    Lead
  • ★Association between vascular endothelial growth factor-mediated blood-brain barrier dysfunction and stress-induced depression
    Hitomi Matsuno; Shoko Tsuchimine; Kazunori O'Hashi; Kazuhisa Sakai; Kotaro Hattori; Shinsuke Hidese; Shingo Nakajima; Shuichi Chiba; Aya Yoshimura; Noriko Fukuzato; Mayumi Kando; Megumi Tatsumi; Shintaro Ogawa; Noritaka Ichinohe; Hiroshi Kunugi; Kazuhiro Sohya
    Molecular Psychiatry, May 2022, Refereed
  • ★A new phenotype identification method with the fluorescent expression in cross-sectioned tails in Thy1-GCaMP6s transgenic mice
    Shutaro Kobayashi; Kazunori O'Hashi; Keisuke Kaneko; Satomi Kobayashi; Shouhei Ogisawa; Morio Tonogi; Satoshi Fujita; Masayuki Kobayashi
    Journal of Oral Science, Apr. 2022, Refereed
  • Reduction in calcium responses to whisker stimulation in the primary somatosensory and motor cortices of the model mouse with trigeminal neuropathic pain.
    Kitano K.; O’Hashi K.; Fujita S.; Kobayashi M.
    J Oral Biosci., 2024, Refereed
  • In Vivo Ca 2+ Imaging of the Insular Cortex during Experimental Tooth Movement
    E Horinuki; K O'Hashi; M Kobayashi
    Journal of Dental Research, Mar. 2021, Refereed, Not invited
  • Presynaptic NK1 Receptor Activation by Substance P Suppresses EPSCs via Nitric Oxide Synthesis in the Rat Insular Cortex
    Sachie Matsumura; Kiyofumi Yamamoto; Yuka Nakaya; Kazunori O'Hashi; Keisuke Kaneko; Hiroki Takei; Hiromasa Tsuda; Tetsuo Shirakawa; Masayuki Kobayashi
    Neuroscience, Feb. 2021, Refereed, Not invited
  • Sirtuin 6 is a regulator of dendrite morphogenesis in rat hippocampal neurons
    Hitomi Matsuno; Shoko Tsuchimine; Noriko Fukuzato; Kazunori O'Hashi; Hiroshi Kunugi; Kazuhiro Sohya
    Neurochemistry International, Jan. 2021, Refereed, Not invited
  • 歯学部での薬理学教育における対面講義とオンライン講義による学修成績の比較検討
    大橋 一徳; 中谷; 有香; 菅原; 詩織; 山本; 清文; 小林 真之
    歯科薬物療法, 2021, Refereed
    Lead
  • Development and Reorganization of Orientation Representation in the Cat Visual Cortex: Experience-Dependent Synaptic Rewiring in Early Life
    Shigeru Tanaka; Masanobu Miyashita; Nodoka Wakabayashi; Kazunori O'Hashi Toshiki Tani; Jérôme Ribot
    Frontiers in Neuroinformatics, Aug. 2020, Refereed, Not invited
  • Comparison of physiological and behavioral responses to chronic restraint stress between C57BL/6J and BALB/c mice
    Shoko Tsuchimine; Hitomi Matsuno; Kazunori O'Hashi; Shuichi Chiba; Aya Yoshimura; Hiroshi Kunugi; Kazuhiro Sohya
    Biochemical and Biophysical Research Communications, Feb. 2020, Refereed, Not invited
  • Construction of the common cortical space by spontaneous activity and its application in the mouse cortex
    O’Hashi K; Sohya K; Matsuno H; Tsushimine S; Kunugi H
    Biochem Biophys Res Commun, 2019, Refereed, Not invited
    Lead
  • Interhemispheric synchrony of spontaneous cortical states at the cortical column level
    O’Hashi K; Fekete T; Deneux T; Hildesheim R; V Leeuwen C; Grinvald A
    Cereb Cortex, 2018, Refereed, Not invited
    Lead
  • Critical dynamics, anesthesia and information integration: Lessons from multi-scale criticality analysis of voltage imaging data
    Fekete T; Omer DB; O’Hashi K; Grinvald A; V Leeuwen C; Shriki O
    Neuroimage, 2018, Refereed, Not invited
  • Mechanisms for shaping receptive field in monkey area TE
    Obara K; O’Hashi K; Tanifuji M
    J Neurophysiol, 2017, Refereed, Not invited
  • Different effects of rotigotine and ropinirole on cholinergic transmission in the mouse medial prefrontal cortex
    Sohya K; O’Hashi K; Kunugi H
    Psychogeriatrics, 2017, Refereed, Not invited
  • Parallel development of orientation maps and spatial frequency selectivity in cat visual cortex
    Tani T; Ribot J; O’Hashi K; Tanaka S
    Eur J Neurosci, 2012, Refereed, Not invited
  • A postnatal critical period for orientation plasticity in the cat visual cortex
    Tanaka S; Tani T; Ribot J; O'Hashi K; Imamura K
    PLoS One, 2009, Refereed, Not invited
  • Anisotropy in the representation of direction preferences in cat area 18
    2)Ribot J; Tanaka S; O'Hashi K; Ajima A
    Eur J Neurosci, 2008, Refereed, Not invited
  • Experience-dependent orientation plasticity in the visual cortex of rats chronically exposed to a single orientation
    O'Hashi K; Miyashita M; Tanaka S
    Neurosci Res, 2007, Refereed, Not invited
    Lead
  • Visualization of neural activity in the rat visual cortex with intrinsic optical imaging.
    Ohashi K.; Tanaka S.
    International Congress Series 1269: Brain-Inspired IT I, 2004, Refereed
    Lead

Affiliated academic society

  • Present
    日本神経科学学会

Research Themes

  • 経頭蓋直流電気刺激法によるマウス血液脳関門透過性の任意制御
    日本学術振興会, 科学研究費助成事業, 01 Apr. 2023 - 31 Mar. 2026
    大橋 一徳; 岡崎 由香
  • 歯痛の位置情報を処理する大脳皮質部位の解明
    日本学術振興会, 科学研究費助成事業, Apr. 2022 - Mar. 2025
    藤田 智史; 大橋 一徳
  • 時系列立体脳機能イメージング法による島皮質神経回路の覚醒下における動作機構の解明
    日本学術振興会, 科学研究費助成事業, Jul. 2021 - Mar. 2023
    小林 真之; 新井 嘉則; 尾崎 弘展; 大橋 一徳
  • Neural homology of major depressive disorder between human and mouse
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Apr. 2020 - Mar. 2023
    大橋 一徳
  • 毛内組織染色によるストレス履歴の可視化
    一般財団法人 ホーユー科学財団, 2020 - 2021
    大橋一徳
  • Sparse modeling to approach spatial and temporal representation of objects in the brain
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Jun. 2013 - Mar. 2018
    Tanifuji Manabu
  • An initial attempt toward brain-machine interface development for manipulatable object recognition
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Apr. 2014 - Mar. 2017
    O'Hashi Kazunori
  • Behavioral task demands modulate object tuning of neurons in the inferior temporal cortex.
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Apr. 2012 - Mar. 2015
    O'HASHI Kazunori
  • 記憶に応じた物体認識に関する 脳内情報表現の取得と操作
    公益財団法人 大川情報通信基金, 2012 - 2013
    大橋一徳