Tohya Yukinobu
| College of Bioresource Sciences Department of Veterinary Medicine | Professor |
Researcher Information
Field Of Study
Research activity information
Paper
- ★Identification and characterization of the genome of a papillomavirus,from skin lesions of four‑toed hedgehogs (Atelerix albiventris)
Yotaro Shimazaki · Shion Yoneya · Shigeru Fujita · Tomomi Nakashima · Kei Nabeshima · Sumire Sudoh ·; Katsuki Matsubara · Naka Okumura · Hirotaka Kondo · Koji Nishifuji · Ryota Koba· Yukinobu Tohya
Virus Genes, Jan. 2023, Refereed, Not invited
Last - ★Identification of amino acid substitutions escaping from a broadly,neutralizing monoclonal antibody of feline calicivirus
Shigeru Fujita; Ryota Koba; Yukinobu Tohya
Virus Research, Jun. 2022, Refereed, Not invited
Last - ★Caliciviruses induce mRNA of tumor necrosis factor alpha via their protease activity
Sekiguchi K; Koba R; Oka T; Tohya Y.
Virus Research, Oct. 2021, Refereed
Last - ★Identification and characterization of a novel bat polyomavirus in Japan
Ryota Koba; Satori Suzuki; Go Sato; Shingo Sato; Kazuo Suzuki; Soichi Maruyama; Yukinobu Tohya
Virus Genes, Aug. 2020, Refereed, Not invited
Last - Inactivation of human norovirus and its surrogate by the disinfectant consisting of calcium hydrogen carbonate mesoscopic crystals.
Shimakura H; Gen-Nagata F; Haritani M; Furusaki K; Kato Y; Yamashita-KAwanishi N; Le DT; Tsuzuki M; Tohya Y; Kyuwa S; Saito H; Horimoto; T Onodera T; Haga T.
FEMS Microbiol Lett, Oct. 2019, Refereed, Not invited - Characterization of a novel species of adenovirus from Japanese microbat and role of CXADR as its entry factor.
Kobayashi T; Matsugo H; Maruyama J; Kamiki H; Takada A; Maeda K; Takenaka-Uema A; Tohya Y; Murakami S; Horimoto T.
Scientific Reports, Jan. 2019, Refereed, Not invited
Lead - Molecular characterization and immune responsive expression of feline MDA5 gene.
Koba R; Shoji S; Toshimura S; Tohya Y.
J Vet Med Sci, Aug. 2018, Refereed, Not invited - Eligibility of feline calicivirus for a surrogate of human norovirus in comparison with murine norovirus , poliovirus and coxsackievirus.
Ohmine T; Marai S; Matsubara T; Nomura T; Fukushi M; Irie T; Komatsu T; Tohya Y; Sakaguchi T.
Biocontrol Sci., Jun. 2018, Refereed, Not invited - A Proposal for a Structural Model of the Feline Calicivirus Protease Bound to the Substrate Peptide under Physiological Conditions
Masaru Yokoyama; Tomoichiro Oka; Hirotaka Takagi; Hirotatsu Kojima; Takayoshi Okabe; Tetsuo Nagano; Yukinobu Tohya; Hironori Sato
FRONTIERS IN MICROBIOLOGY, Jul. 2017, Refereed, Not invited - Nonstructural protein p39 of feline calicivirus suppresses host innate immune response by preventing IRF-3 activation
Yo Yumiketa; Takanori Narita; Yosuke Inoue; Go Sato; Wataru Kamitani; Tomoichiro Oka; Kazuhiko Katayama; Takemasa Sakaguchi; Yukinobu Tohya
VETERINARY MICROBIOLOGY, Mar. 2016, Refereed, Not invited - Novel cyclovirus detected in the intestinal contents of Taiwan squirrels (Callosciurus erythraeus thaiwanensis)
Go Sato; Taketo Kawashima; Masahiro Kiuchi; Yukinobu Tohya
VIRUS GENES, Aug. 2015, Refereed, Not invited - Development of a novel single step reverse genetics system for feline calicivirus
Tomoichiro Oka; Hirotaka Takagi; Yukinobu Tohya
JOURNAL OF VIROLOGICAL METHODS, Oct. 2014, Refereed, Not invited - Characterization of St-Valerien-like virus genome detected in Japan
Sato G; Ido H; Kiuchi M; Kataoka M; Katayama K; Tohya Y.
J Vet Med Sci, Jul. 2014, Refereed, Not invited
Corresponding - The virucidal effect against murine norovirus and feline calicivirus as surrogates for human norovirus by ethanol-based sanitizers
Yuko Shimizu-Onda; Tempei Akasaka; Fumihiro Yagyu; Shihoko Komine-Aizawa; Yukinobu Tohya; Satoshi Hayakawa; Hiroshi Ushijima
JOURNAL OF INFECTION AND CHEMOTHERAPY, Aug. 2013, Refereed, Not invited - Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts from Persimmon (Diospyros kaki) on a Broad Range of Viruses.
Ueda K; Kawabata R; Irie T; Nakai Y; Tohya Y; Sakaguchi T.
PLoS One, Jan. 2013, Refereed, Not invited - Effect of hypochlorite-based disinfectants on inactivation of murine norovirus and attempt to eliminate or prevent infection in mice by addition to drinking water
Kazuhiro Takimoto; Motoko Taharaguchi; Koji Sakai; Hirotaka Takagi; Yukinobu Tohya; Yasuko K. Yamada
Experimental Animals, 2013, Refereed, Not invited - Novel murine norovirus-like genes in wild rodents in Japan.
Tsunesumi N; Sato G; Iwasa M; Kabeya H; Maruyama S; Tohya Y.
J Vet Med Sci, Sep. 2012, Refereed, Not invited
Corresponding - Equine herpesvirus 4: recent advances using BAC technology.
Azab W; Kato K; Abdel-Gawad A; Tohya Y; Akashi H.
Veterinary Microbiology, May 2011, Refereed, Not invited - Development of a real-time RT-PCR assay combined with ethidium monoazide treatment for RNA viruses and its application to detect viral RNA after heat exposure.
Kim K; Katayama H; Kitajima M; Tohya Y; Ohgaki S.
Water Science and Technology, Apr. 2011, Refereed, Not invited - Bioluminescence technologies to detect calicivirus protease activity in cell-free system and in infected cells.
Oka T; Takagi H; Tohya Y; Murakami K; Takeda N; Wkita T; Katayama K.
Antiviral Research, Apr. 2011, Refereed, Not invited - Development and application of a broadly reactive real-time reverse transcription-PCR assay for detection of murine norovirus.
Kitajima; M.; Oka; T.; Takagi; H.; Tohya; Y.; Katayama; H.; Takeda; N. and Katayama; K.
J. Virol. Methods, Nov. 2010, Refereed, Not invited - Bat coronaviruses and experimental infection of bats, the Philippines.
Watanabe S; Masangkay JS; Nagata N; Morikawa S; Mizutani T; Fukushi S; Alviola P; Omatsu T; Ueda N; Iha K; Taniguchi S; Fujii H; Tsuda S; Endoh M; Kato K; Tohya Y; Kyuwa S; Yoshikawa Y; Akashi H.
Emerging Infectious Diseases, Aug. 2010, Refereed, Not invited - Bovine viral diarrhea virus non-structural protein 5A interacts with NIK- and IKKbeta-binding protein.
Zahoor MA; Yamane D; Mohamed YM; Suda Y; Kobayashi K; Kato K; Tohya Y; Akashi H.
Journal of General Virology, Aug. 2010, Refereed, Not invited - Chlorine inactivation of human norovirus, murine norovirus and poliovirus in drinking water.
Kitajima M; Tohya Y; Matsubara K; Haramoto E; Utagawa E; Katayama H.
Lett. Appl. Microbiol., Jul. 2010, Refereed, Not invited - Functional analysis of Rousettus aegyptiacus "signal transducer and activator of transcription 1" (STAT1).
Fujii H; Watanabe S; Yamane D; Ueda N; Iha K; Taniguchi S; Kato K; Tohya Y; Kyuwa S; Yoshikawa Y; Akashi H.
Dev. Comp. Immunol., May 2010, Refereed, Not invited - Nosocomial outbreak of serious canine infectious tracheobronchitis (kennel cough) caused by canine herpesvirus infection.
Kawakami K; Ogawa H; Maeda K; Imai A; Ohashi E; Matsunaga S; Tohya Y; Ohshima T; Mochizuki M.
Journal of Clinical Microbiology, Apr. 2010, Refereed, Not invited - Characterization of a thymidine kinase-deficient mutant of equine herpesvirus 4 and in vitro susceptibility of the virus to antiviral agents.
Azab W; Tsujimura K; Kato K; Arii J; Morimoto T; Kawaguchi Y; Tohya Y; Matsumura T; Akashi H.
Antiviral Res., Feb. 2010, Refereed, Not invited - Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice.
Kitagawa Y; Tohya Y; Ike F; Kajita A; Park SJ; Ishii Y; Kyuwa S; Yoshikawa Y.
Exp. Anim., Feb. 2010, Refereed, Not invited - Plasmodium falciparum BAEBL binds to heparan sulfate proteoglycans on the human erythrocyte surface.
Kobayashi K; Kato K; Sugi T; Takemae H; Pandey K; Gong H; Tohya Y; Akashi H.
J Biol Chem, Jan. 2010, Refereed, Not invited - Epizootology and experimental infection of Yokose virus in bats.
Watanabe S; Omatsu T; Miranda ME; Masangkay JS; Ueda N; Endo M; Kato K; Tohya Y; Yoshikawa Y; Akashi H.
Comp Immunol Microbiol Infect Dis, Jan. 2010, Refereed, Not invited - Molecular analyses of Toxoplasma gondii calmodulin-like domain protein kinase isoform 3.
Sugi T; Kato K; Kobayashi K; Pandey K; Takemae H; Kurokawa H; Tohya Y; Akashi H.
Parasitol Int, Dec. 2009, Refereed, Not invited - Characterization of Plasmodium falciparum calcium-dependent protein kinase 4.
Kato K; Sudo A; Kobayashi K; Sugi T; Tohya Y; Akashi H.
Parasitol Int, Dec. 2009, Refereed, Not invited - Characterization and application of monoclonal antibodies to bovine viral diarrhea virus nonstructural protein 5A.
Zahoor MA; Yamane D; Mohamed YM; Kobayashi K; Kato K; Tohya Y; Akashi H.
Arch Virol., Oct. 2009, Refereed, Not invited - Development of a broadly reactive nested reverse transcription-PCR assay to detect murine noroviruses, and investigation of the prevalence of murine noroviruses in laboratory mice in Japan.
Kitajima M; Oka T; Tohya Y; Katayama H; Takeda N; Katayama K.
Microbiol Immunol., Sep. 2009, Refereed, Not invited - Detection of a new bat gammaherpesvirus in the Philippines.
Watanabe S; Ueda N; Iha K; Masangkay JS; Fujii H; Alviola P; Mizutani T; Maeda K; Yamane D; Walid A; Kato K; Kyuwa S; Tohya Y; Yoshikawa Y; Akashi H.
Virus Genes, Aug. 2009, Refereed, Not invited - Analysis of herpesvirus host specificity determinants using herpesvirus genomes as bacterial artificial chromosomes.
Arii J; Kato K; Kawaguchi Y; Tohya Y; Akashi H.
Microbiol Immunol, Aug. 2009, Refereed, Not invited - Activation of extracellular signal-regulated kinase in MDBK cells infected with bovine viral diarrhea virus.
Yamane D; Zahoor MA; Mohamed YM; Azab W; Kato K; Tohya Y; Akashi H.
Arch Virol, Jul. 2009, Refereed, Not invited - Microarray analysis reveals distinct signaling pathways transcriptionally activated by infection with bovine viral diarrhea virus in different cell types.
Yamane D; Zahoor MA; Mohamed YM; Azab W; Kato K; Tohya Y; Akashi H.
Virus Res, Jun. 2009, Refereed, Not invited - Application of retrovirus-mediated expression cloning for receptor screening of a parasite.
Kobayashi K; Kato K; Sugi T; Yamane D; Shimojima M; Tohya Y; Akashi H.
Anal Biochem, Jun. 2009, Refereed, Not invited - Inhibition of sphingosine kinase by bovine viral diarrhea virus NS3 is crutial for efficient viral replication and cytopathgenesis.
Daisuke Yamane; Muhammad A. Zahoor; Yassir M. Mohamad; Walid Azab; Kentaro Kato; Yukinobu Tohya; Hiroomi Akashi
Journal of Biological Chemistry, May 2009, Refereed, Not invited - Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses
Yukinobu Tohya; Krishna Narayanan; Wataru Kamitani; Cheng Huang; Kumari Lokugamage; Shinji Makino
Journal of Virology, May 2009, Refereed, Not invited
Lead - Cloning of the genome of equine herpesvirus 4 strain TH20p as an infectious bacterial artificial chromosome.
Azab W; Kato K; Arii J; Tsujimura K; Yamane D; Tohya Y; Matsumura T; Akashi H.
Arch Virol, Apr. 2009, Refereed, Not invited - Characterization of Plasmodium falciparum protein kinase 2.
Kato K; Sudo A; Kobayashi K; Tohya Y; Akashi H.
Mol Biochem Parasitol, Nov. 2008, Refereed, Not invited - Ligation-mediated amplification for effective rapid determination of viral RNA sequences (RDV).
Watanabe S; Mizutani T; Sakai K; Kato K; Tohya Y; Fukushi S; Saijo M; Yoshikawa Y; Kurane I; Morikawa S; Akashi H.
J Clin Virol, Sep. 2008, Refereed, Not invited - Susceptibility of Plasmodium falciparum cyclic AMP-dependent protein kinase and its mammalian homologue to the inhibitors.
Sudo A; Kato K; Kobayashi K; Tohya Y; Akashi H.
Mol Biochem Parasitol, Aug. 2008, Refereed, Not invited - Chronological analysis of canine parvovirus type 2 isolates in Japan.
Ohshima T; Hisaka M; Kawakami K; Kishi M; Tohya Y; Mochizuki M.
J Vet Med Sci, Aug. 2008, Refereed, Not invited - Induction and sequencing of Rousette bat interferon alpha and beta genes.
Omatsu T; Bak EJ; Ishii Y; Kyuwa S; Tohya Y; Akashi H; Yoshikawa Y.
Vet Immunol Immunopathol, Jul. 2008, Refereed, Not invited - The relationship between the viral RNA level and upregulation of innate immunity in spleen of cattle persistently infected with bovine viral diarrhea virus.
Yamane D; Kato K; Tohya Y; Akashi H.
Vet Microbiol, May 2008, Refereed, Not invited - Rescue of Akabane virus (family Bunyaviridae) entirely from cloned cDNAs by using RNA polymerase I.
Ogawa Y; Sugiura K; Kato K; Tohya Y; Akashi H.
J Gen Virol, Dec. 2007, Refereed, Not invited - Comparison of Akabane virus isolated from sentinel cattle in Japan.
Ogawa Y; Fukutomi T; Sugiura K; Sugiura K; Kato K; Tohya Y; Akashi H.
Vet Microbiol, Sep. 2007, Refereed, Not invited - Characterization of temperature-sensitive Akabane virus mutants and their roles in attenuation.
Ogawa Y; Kato K; Tohya Y; Akashi H.
Arch Virol, Sep. 2007, Refereed, Not invited - Highly conserved configuration of catalytic amino acid residues among calicivirus-encoded protease
Tomoichiro Oka; Mami Yamamoto; Masaru Yokoyama; Satoko Ogawa; Grant S. Hansman; Kazuhiko Katayama; Kana Miyashita; Hirotaka Takagi; Yukinobu Tohya; Hironori Sato; Naokazu Takeda
Journal of Virology, Jul. 2007, Refereed, Not invited - Sequence determination and functional analysis of the Akabane virus (family Bunyaviridae) L RNA segment.
Ogawa Y; Kato K; Tohya Y; Akashi H.
Arch Virol, May 2007, Refereed, Not invited - Molecular cloning of a cDNA encoding the feline CD62L.
Nishimura Y; Shimojima M; Tohya Y; Miyazawa T.
J Vet Med Sci., Jan. 2007, Refereed, Not invited - Genetic analysis of calicivirus genomes detected in intestinal contents of piglets in Japan
Y. Yin; Y. Tohya; Y. Ogawa; K. Kato; H. Akashi
Archives of Virology, Sep. 2006, Refereed, Not invited
Corresponding - Junctional adhesion molecule 1 is a functional receptor for feline calicivirus
Akiko Makino; Masayuki Shimojima; Takayuki Miyazawa; Kentaro Kato; Yukinobu Tohya; Hiroomi Akashi
Journal of Virology, May 2006, Refereed, Not invited
Corresponding - Construction of an infectious clone of canine herpesvirus genome as a bacterial artificial chromosome
Jun Arii; Orkesh Hushur; Kentaro Kato; Yashushi Kawaguchi; Yukinobu Tohya; Hiroomi Akashi
Microbes and Infection, Apr. 2006, Refereed, Not invited
Corresponding - A novel antigenic variant of Canine parvovirus from a Vietnamese dog
M. Nakamura; Y. Tohya; T. Miyazawa; M. Mochizuki; H.T.T. Phung; N.H. Nguyen; L.M.T. Huynh; L.T. Nguyen; P.N. Nguyen; P.V. Nguyen; N.P.T. Nguyen; H.Akashi
Archives of Virology, Nov. 2004, Refereed, Not invited
Corresponding - Early interaction of canine calicivirus with cells is the major determinant for its cell tropism in vitro
Maeda Y; Tohya Y; Matsuura Y; Mochizuki M; Sugimura T.
Veterinary Microbiology, Jul. 2002, Refereed, Not invited
Corresponding - Identification of conformatinal neutralizing epitopes on the capsid proteion of canine calicivirus
Yuichi Matsuura; Yukinobu Tohya; Masami Mochizuki; Kozo Takase; Takaaki Sugumura
Journal of General Virology, Jul. 2001, Refereed, Not invited
Corresponding - Mapping of antigenic sites involved in neutralization on the capsid protein of feline calicivirus
Yukinobu Tohya; Naoaki Yokoyama; Ken Maeda; Yasushi Kawaguchi; Takeshi Mikami
Journal of General Virology, Feb. 1997, Refereed, Not invited
Lead
MISC
Books and other publications
Research Themes
- Further characterization of porcine enterie caliciviruses
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2010 - 2012
TOHYA Yukinobu - 伴侶動物のための遺伝子治療を目指した新しいヘルペスウイルスベクターの開発
日本学術振興会, 科学研究費助成事業, 2004 - 2006
明石 博臣; 遠矢 幸伸 - Studies on emerging diseases derived from Primates and Chiroptera
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2004 - 2006
AKASHI Hiroomi; YOSHIKAWA Yasuhiro; HONDO Ryou; MORIKAWA Shigeru; TOHYA Yukinobu; KYUWA Shigeru - Evolution and host adaptation strategy of carnivorous parvoviruses
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2003 - 2004
TOHYA Yukinobu; MOCHIZUKI Masami - 我が国とアルゼンチン国における動物疾病の発症状況とその特色
日本学術振興会, 科学研究費助成事業, 2003 - 2003
小野 憲一郎; 辻本 元; 土井 邦雄; 小川 博之; 遠矢 幸伸; 西村 亮平 - Use of interferon-τ for generation of viral resistant animals.
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2001 - 2002
KAZUHIKO Imakawa; SAKAI Senkiti; TOHYA Yukinobu; MIYAZAWA Takayuki; SENTUI Hiroshi - Development of methods that facilitate generation of recombinant herpesviruses using BAC system
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2000 - 2002
KAWAGUCHI Yasushi; MAEDA Ken; HORIMOTO Taisuke; MIKAMI Takeshi; TANAKA Michiko; TOHYA Yukinobu - Analysis of factors determining the host range of calicviruses
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1999 - 2001
TOHYA Yukinobu - Research on the immunological responses of cats against feline immunodeficiency virus
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1999 - 2001
SHITA Kunio; TOHYA Yukinobu; AKASHI Hiroomi; TAKAHASHI Eiji; MAEDA Ken; MIYAZAWA Takayuki - ネコカリシウィルス非構造蛋白の同定とその機能の解析
日本学術振興会, 科学研究費助成事業, 1997 - 1998
遠矢 幸伸 - MUTATIONS IN ALPHAHERPESVIRUSES WITH VARIOUS GENOMIC GC CONTENTS.
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1996 - 1998
OTSUKA Haruki; TOHYA Yukinobu; MATSUMOTO Yasunobu; MIKAMI Takeshi; YAMADA Syunji; HORIMOTO Taisuke - Host Range Specificity of Herpesvirus
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1995 - 1996
OTSUKA Haruki; THOYA Yukinobu - ネコカリシウイルス非構造蛋白遺伝子の発現とプロセッシング機構の解析
日本学術振興会, 科学研究費助成事業, 1995 - 1995
遠矢 幸伸 - Development of cytotoxicity test for outbred animals using recombinant viruses.
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1993 - 1995
KAI Chieko; AIDA Yohko; IHARA Takeshi; YAMANOUCHI Kazuya; FUMIO Kobune; SAITOH Izumi - ネコカリシウイルスの抗原性に関与する遺伝的多様性の解析とタイピング法の開発
日本学術振興会, 科学研究費助成事業, 1994 - 1994
遠矢 幸伸 - Development of polyvalent recombinant vaccines for chickens and companion animals
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1992 - 1994
MIKAMI Takeshi; HIRAI Kanji; HIRAI Katusya; TOHYA Yukinobu; TUCHIYA Kotaro; KAI Chieko - 猫カリキウイルスの抗原構造の解析
日本学術振興会, 科学研究費助成事業, 1993 - 1993
遠矢 幸伸 - Studies on the mechanisms of persistent infection and reactivation of animal viruses
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1991 - 1993
MIKAMI Takeshi; GOITSUKA Ryo; TOHYA Yukinobu; TSUJIMOTO Hajime; KAI Chieko - 牛疫ウイルスによって誘発される免疫不全機序の研究
日本学術振興会, 科学研究費助成事業, 1992 - 1992
甲斐 知恵子; 山内 一也; 遠矢 幸伸 - ネコ免疫不全ウイルスによるエイズの動物病態モデルの確立とその解析
日本学術振興会, 科学研究費助成事業, 1991 - 1991
見上 彪; 遠矢 幸伸; 新倉 昌浩; 甲斐 知恵子 - ネコ免疫不全ウイルスによるエイズの動物病態モデルの確立とその解析
日本学術振興会, 科学研究費助成事業, 1990 - 1990
見上 彪; 遠矢 幸伸; 畔高 政行; 高橋 英司 - The Role of Tumor-Associated Antigen in Tumor Immunity
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 1988 - 1990
MIKAMI Takeshi; TOHYA Yukinobu; AZETAKA Masayuki; KODAMA Hiroshi; TAKAHASHI Eiji; TAKAHASHI Michio
