Hashimoto Osamu
| College of Bioresource Sciences Department of Veterinary Medicine | Professor |
Researcher Information
Field Of Study
Career
- Apr. 2022 - Present
Nihon University, College of Bioresource Sciences Department of Veterinary Medicine, Professor - Apr. 2022 - Mar. 2023
長浜バイオ大学 バイオサイエンス学部 非常勤講師 - Apr. 2018 - Mar. 2023
Kagawa University, Faculty of Medicine, 非常勤講師 - Apr. 2020 - Mar. 2022
Nagahama Institute of Bio-Science and Technology, Department of Bio-Science, Professor - Jul. 2013 - Mar. 2020
Kitasato University, School of Veterinary Medicine, 准教授 - Apr. 2016 - Mar. 2017
Kagawa University, Faculty of Medicine, 非常勤講師 - 2007 - 2013
Kitasato University, School of Veterinary Medicine, 専任講師 - 2003 - 2004
UCSD School of Medicine, Post doctral fellow - 1999 - 2001
Kitasato University, 専任講師 - Apr. 1997 - Mar. 1999
National Institute of Health Sciences, 流動研究員 - 1997 - 1999
国立医薬品食品衛生研究所 流動研究員
Educational Background
Research activity information
Award
Paper
- ★Activin E upregulates uncoupling protein 1 and fibroblast growth factor 21 in brown adipocytes
Maho Sakaki; Yuji Kamatari; Akira Kurisaki; Masayuki Funaba; Osamu Hashimoto
Molecular and Cellular Endocrinology, Oct. 2024, Refereed
Corresponding - ★Dermocystid infection in Japanese fire-bellied newt, Cynops pyrrhogaster
Go KAWAHARA; Yuta TAKAYAMA; Makoto SUGIYAMA; Hiromi IKADAI; Osamu HASHIMOTO
Journal of Veterinary Medical Science, Oct. 2022, Refereed
Corresponding - ★Activin E enhances insulin sensitivity and thermogenesis by activating brown/beige adipocytes.
Kazunari Sekiyama; Yuuki Ushiro; Akira Kurisaki; Masayuki Funaba; Osamu Hashimoto
The Journal of veterinary medical science, May 2019, Refereed, Not invited
Corresponding - ★Inducible brown/beige adipocytes in retro-orbital adipose tissues.
Sugiyama M; Shindo D; Kanada N; Ohzeki T; Yoshioka K; Funaba M; Hashimoto O
Exp. Eye Res., Apr. 2019, Refereed, Not invited
Corresponding - ★Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine.
Osamu Hashimoto; Masayuki Funaba; Kazunari Sekiyama; Satoru Doi; Daichi Shindo; Ryo Satoh; Hiroshi Itoi; Hiroaki Oiwa; Masahiro Morita; Chisato Suzuki; Makoto Sugiyama; Norio Yamakawa; Hitomi Takada; Shigenobu Matsumura; Kazuo Inoue; Seiichi Oyadomari; Hiromu Sugino; Akira Kurisaki
Cell reports, Oct. 2018, Refereed, Not invited
Lead - ★Castration induced browning in subcutaneous white adipose tissue in male mice
Osamu Hashimoto; Tatsuya Noda; Atsushi Morita; Masahiro Morita; Hirofumi Ohtsuki; Makoto Sugiyama; Masayuki Funaba
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Sep. 2016, Refereed, Not invited
Lead - Regulatory mechanisms underlying interleukin-6 expression in murine brown adipocytes.
Xiajie Fu; Masaru Murakami; Osamu Hashimoto; Tohru Matsui; Masayuki Funaba
Cell biochemistry and function, Jan. 2024 - Detection and molecular analysis of Philopinna higai (Digenea: Didymozoidae) from domestically introduced Sarcocheilichthys fishes in the Tohoku region, Japan.
Sakure Nakamura; Motoki Shioneri; Jun Hakozaki; Kazuhiko Nakayama; Kodai Kusakisako; Osamu Hashimoto; Wataru Kakino; Hiromi Ikadai
Parasitology international, Dec. 2023 - Stimulation of uncoupling protein 1 expression by β-alanine in brown adipocytes
Tsukasa Hamaoka; Xiajie Fu; Shozo Tomonaga; Osamu Hashimoto; Masaru Murakami; Masayuki Funaba
Archives of Biochemistry and Biophysics, Sep. 2022 - Identification and expression of bovine Ucp1 variants
Zhicheng Diao; Masaru Murakami; Reiichiro Sato; Fumie Shimokawa; Manami Matsumura; Osamu Hashimoto; Ken Onda; Mitsuyuki Shirai; Tohru Matsui; Masayuki Funaba
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Apr. 2022 - Vaginal mucus in mice: Developmental and gene expression features of epithelial mucous cells during pregnancy.
Makoto Sugiyama; Nao Machida; Arata Yasunaga; Nanako Terai; Hanae Fukasawa; Hisaya K Ono; Ryosuke Kobayashi; Keita Nishiyama; Osamu Hashimoto; Shiro Kurusu; Kazuki Yoshioka
Biology of reproduction, Aug. 2021 - Improvement in identification of pro-estrous mice by using a novel method of detecting vaginal mucous cells.
Makoto Sugiyama; Arata Yasunaga; Ryosuke Kobayashi; Hanae Fukasawa; Osamu Hashimoto; Shiro Kurusu; Hiroshi Sasada; Kazuki Yoshioka
Cell and tissue research, Mar. 2021 - Response to iron overload in cultured hepatocytes.
Hsuan-Ju Chen; Makoto Sugiyama; Fumie Shimokawa; Masaru Murakami; Osamu Hashimoto; Tohru Matsui; Masayuki Funaba
Scientific reports, Dec. 2020 - Regulatory expression of bone morphogenetic protein 6 by 2,2'-dipyridyl.
Taiki Noguchi; Mayuko Ikeda; Masaru Murakami; Mikio Masuzawa; Toru Imamura; Osamu Hashimoto; Tohru Matsui; Masayuki Funaba
Biochimica et biophysica acta. General subjects, Aug. 2020, Refereed, Not invited - Data on induction of brown/beige adipocytes in mouse retro-orbital adipose tissues.
Makoto Sugiyama; Masayuki Funaba; Osamu Hashimoto
Data in brief, Dec. 2019, Refereed, Not invited
Corresponding - Chronic retinoic acid treatment induces differentiation and changes in the metabolite levels of brown (pre)adipocytes.
Mika Suzuki; Hsuan-Ju Chen; Shozo Tomonaga; Osamu Hashimoto; Teruo Kawada; Tohru Matsui; Masayuki Funaba
Cell biochemistry and function, Jul. 2019, Refereed, Not invited - Hepcidin and IL-1β.
Kanamori Y; Murakami M; Sugiyama M; Hashimoto O; Matsui T; Funaba M
Vitamins and hormones, 2019, Refereed, Not invited - Identification and expression of the medaka inhibin βE subunit.
Morita M; Hashimoto O
Mol. Biol. Rep., 2019, Refereed, Not invited
Corresponding - Metabolic changes in adipose tissues in response to β3 -adrenergic receptor activation in mice.
Yusuke Fujimoto; Osamu Hashimoto; Daichi Shindo; Makoto Sugiyama; Shozo Tomonaga; Masaru Murakami; Tohru Matsui; Masayuki Funaba
Journal of cellular biochemistry, Jan. 2019, Refereed, Not invited - Metabolic changes in adipose tissues in response to β3 -adrenergic receptor activation in mice.
Yusuke Fujimoto; Osamu Hashimoto; Daichi Shindo; Makoto Sugiyama; Shozo Tomonaga; Masaru Murakami; Tohru Matsui; Masayuki Funaba
Journal of cellular biochemistry, Jan. 2019, Refereed, Not invited - Role of estradiol and testosterone in Ucp1 expression in brown/beige adipocytes.
Mika Suzuki; Masaru Murakami; Mitsuyuki Shirai; Osamu Hashimoto; Teruo Kawada; Tohru Matsui; Masayuki Funaba
Cell biochemistry and function, Dec. 2018, Refereed, Not invited - Supra-pharmacological concentration of capsaicin stimulates brown adipogenesis through induction of endoplasmic reticulum stress.
Ryosuke Kida; Taiki Noguchi; Masaru Murakami; Osamu Hashimoto; Teruo Kawada; Tohru Matsui; Masayuki Funaba
Scientific reports, Jan. 2018, Refereed, Not invited - Interleukin-1 beta (IL-1 beta) transcriptionally activates hepcidin by inducing CCAAT enhancer-binding protein delta (C/EBP delta) expression in hepatocytes
Yohei Kanamori; Masaru Murakami; Makoto Sugiyama; Osamu Hashimoto; Tohru Matsui; Masayuki Funaba
JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 2017, Refereed, Not invited - Regulation of hepcidin expression by inflammation-induced activin B
Yohei Kanamori; Makoto Sugiyama; Osamu Hashimoto; Masaru Murakami; Tohru Matsui; Masayuki Funaba
Scientific Reports, Dec. 2016, Refereed, Not invited - Modulation of brown adipocyte activity by milk by-products: Stimulation of brown adipogenesis by buttermilk
Hiroki Asano; Ryosuke Kida; Kengo Muto; Takayuki Y. Nara; Ken Kato; Osamu Hashimoto; Teruo Kawada; Tohru Matsui; Masayuki Funaba
CELL BIOCHEMISTRY AND FUNCTION, Dec. 2016, Refereed, Not invited - Expression of uncoupling protein 1 in bovine muscle cells
M. A. Abd Eldaim; O. Hashimoto; H. Ohtsuki; T. Yamada; M. Murakami; K. Onda; R. Sato; Y. Kanamori; Y. Qiao; S. Tomonaga; T. Matsui; M. Funaba
JOURNAL OF ANIMAL SCIENCE, Dec. 2016, Refereed, Not invited - Direct action of capsaicin in brown adipogenesis and activation of brown adipocytes
Ryosuke Kida; Hirofumi Yoshida; Masaru Murakami; Mitsuyuki Shirai; Osamu Hashimoto; Teruo Kawada; Tohru Matsui; Masayuki Funaba
CELL BIOCHEMISTRY AND FUNCTION, Jan. 2016, Refereed, Not invited - Brown Adipose Tissue in Cetacean Blubber
Osamu Hashimoto; Hirofumi Ohtsuki; Takehiko Kakizaki; Kento Amou; Ryo Sato; Satoru Doi; Sara Kobayashi; Ayaka Matsuda; Makoto Sugiyama; Masayuki Funaba; Takashi Matsuishi; Fumio Terasawa; Junji Shindo; Hideki Endo
PLOS ONE, Feb. 2015, Refereed, Not invited
Lead - Regulation of brown adipogenesis by the Tgf-β family: involvement of Srebp1c in Tgf-β- and Activin-induced inhibition of adipogenesis.
Hirofumi Yoshida; Yohei Kanamori; Hiroki Asano; Osamu Hashimoto; Masaru Murakami; Teruo Kawada; Tohru Matsui; Masayuki Funaba
Biochimica et biophysica acta, Nov. 2013, Refereed, Not invited - Comparative morphological examinations of the cervical and thoracic vertebrae and related spinal nerves in the two-toed sloth
Hideki Endo; Osamu Hashimoto; Hajime Taru; Keisuke Sugimura; Shin-ichi Fujiwara; Takuya Itou; Hiroshi Koie; Masato Kitagawa; Takeo Sakai
MAMMAL STUDY, Sep. 2013, Refereed, Not invited - Expression of Activin Receptor-like Kinase 7 in Adipose Tissues
Masaru Murakami; Mitsuyuki Shirai; Ryo Ooishi; Asako Tsuburaya; Kumiko Asai; Osamu Hashimoto; Kenji Ogawa; Yoshii Nishino; Masayuki Funaba
BIOCHEMICAL GENETICS, Apr. 2013, Refereed, Not invited - Diet-induced changes in Ucp1 expression in bovine adipose tissues
Hiroki Asano; Tomoya Yamada; Osamu Hashimoto; Takenao Umemoto; Ryo Sato; Shiori Ohwatari; Yohei Kanamori; Tomohiro Terachi; Masayuki Funaba; Tohru Matsui
GENERAL AND COMPARATIVE ENDOCRINOLOGY, Apr. 2013, Refereed, Not invited - Identification and characterization of canine growth differentiation factor-9 and its splicing variant
Osamu Hashimoto; Ryohei Takagi; Fuminari Yanuma; Satoru Doi; Junji Shindo; Hideki Endo; Yoshihisa Hasegawa; Shunichi Shimasaki
GENE, May 2012, Refereed, Not invited
Lead - Molecular Cloning and Expression of Canine Prolactin Gene
Osamu Hashimoto; Tomohiro Yonezawa; Yuka Sugiyama; Mitsumori Kawaminami; Yoshihisa Hasegawa
EXPERIMENTAL ANIMALS, Oct. 2010, Refereed, Not invited
Lead - Implication of activin E in glucose metabolism: Transcriptional regulation of the inhibin/activin beta E subunit gene in the liver
Osamu Hashimoto; Kazunari Sekiyama; Tsuyoshi Matsuo; Yoshihisa Hasegawa
LIFE SCIENCES, Sep. 2009, Refereed, Not invited
Lead - Gene expression of the TGF-beta family in rat brain infected with Borna disease virus
Yoshii Nishino; Ryo Ooishi; Sachiko Kurokawa; Kan Fujino; Masaru Murakami; Hiroo Madarame; Osamu Hashimoto; Kazutoshi Sugiyama; Masayuki Funaba
MICROBES AND INFECTION, Jul. 2009, Refereed, Not invited - Abnormalities in aggression and anxiety in transgenic mice overexpressing activin E
Kazunari Sekiyama; Osamu Hashimoto; Yuuki Ushiro; Chika Adachi; Takefumi Kikusui; Kentaro Tanemura; Yoshihisa Hasegawa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2009, Refereed, Not invited
Corresponding - Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice
Heather E. McMahon; Osamu Hashimoto; Pamela L. Mellon; Shunichi Shimasaki
ENDOCRINOLOGY, Jun. 2008, Refereed, Not invited - Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice
Masashi Nakatani; Yuka Takehara; Hiromu Sugino; Mitsuru Matsumoto; Osamu Hashimoto; Yoshihisa Hasegawa; Tatsuya Murakami; Akiyoshi Uezumi; Shin'ichi Takeda; Sumihare Noji; Yoshihide Sunada; Kunihiro Tsuchida
FASEB JOURNAL, Feb. 2008, Refereed, Not invited - Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development
Yuka Takehara-Kasamatsu; Kunihiro Tsuchida; Masashi Nakatani; Tatsuya Murakami; Akira Kurisaki; Osamu Hashimoto; Hideyo Ohuchi; Hitomi Kurose; Kazuhiro Mori; Shoji Kagami; Sumihare Noji; Hiromu Sugino
Journal of Medical Investigation, 2007, Refereed, Not invited - Analysis of the function of activin beta(C) subunit using recombinant protein
Yuuki Ushiro; Osamu Hashimoto; Machi Seki; Akitsu Hachiya; Hiroki Shoji; Yoshihisa Hasegawa
JOURNAL OF REPRODUCTION AND DEVELOPMENT, Aug. 2006, Refereed, Not invited
Corresponding - Impaired growth of pancreatic exocrine cells in transgenic mice expressing human activin beta E subunit
O Hashimoto; Y Ushiro; K Sekiyama; O Yamaguchi; K Yoshioka; K Mutoh; Y Hasegawa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Mar. 2006, Refereed, Not invited
Lead - Posttranslational processing of mouse and human BMP-15: Potential implication in the determination of ovulation quota
O Hashimoto; RK Moore; S Shimasaki
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2005, Not refereed, Not invited
Lead - Activin isoforms signal through type I receptor serine/threonine kinase ALK7
K Tsuchida; M Nakatani; N Yamakawa; O Hashimoto; Y Hasegawa; H Sugino
MOLECULAR AND CELLULAR ENDOCRINOLOGY, May 2004, Not refereed, Not invited - cDNA cloning and expression of human activin beta E subunit
O Hashimoto; K Tsuchida; Y Ushiro; Y Hosoi; N Hoshi; H Sugino; Y Hasegawa
MOLECULAR AND CELLULAR ENDOCRINOLOGY, Aug. 2002, Not refereed, Not invited
Lead - Possible involvement of protein kinases and Smad2 signaling pathways on osteoclast differentiation enhanced by activin A.
Murase, Y; Okahashi, N; Koseki, T; Itoh, K; Udagawa, N; Hashimoto, O; Sugino, H; Noguchi, T; Nishihara, T
J. Cell. Physiol., 188, 236-242., Jul. 2001, Refereed, Not invited - Activin A and follistatin control osteoclast differentiation through a smad2 signaling pathway
Murase, Y; Okahashi, N; Koseki, T; Itoh, K; Udagawa, N; Hashimoto, O; Sugino, H; Nishihara, T
Journal of Cellular Physiology, 2001, Not refereed, Not invited - Crocus sativus lectin recognizes Man(3)GlcNAc in the N-glycan core structure
Y Oda; K Nakayama; B Abdul-Rahman; M Kinoshita; O Hashimoto; N Kawasaki; T Hayakawa; K Kakehi; N Tomiya; YC Lee
JOURNAL OF BIOLOGICAL CHEMISTRY, Sep. 2000, Refereed, Not invited - Difference between follistatin isoforms in the inhibition of activin signalling - Activin neutralizing activity of follistatin isoforms is dependent on their affinity for activin
O Hashimoto; N Kawasaki; K Tsuchida; S Shimasaki; T Hayakawa; H Sugino
CELLULAR SIGNALLING, Aug. 2000, Refereed, Not invited
Lead - Expression of inhibin beta(A), beta(B), and follistatin mRNAs in the carbon tetrachloride induced rat liver regeneration model
T Kobayashi; S Niimi; O Hashimoto; T Hayakawa
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Jun. 2000, Refereed, Not invited - Possible role of hepatocyte growth factor/scatter factor and activin A produced by the target organ in liver metastasis
S Hyuga; N Kawasaki; O Hashimoto; M Hyuga; M Ohta; S Yamagata; T Yamagata; T Hayakawa
CANCER LETTERS, May 2000, Refereed, Not invited - Possible role of hepatocyte growth factor/scatter factor and activin A produced by the target organ in liver metastasis
S Hyuga; N Kawasaki; O Hashimoto; M Hyuga; M Ohta; S Yamagata; T Yamagata; T Hayakawa
CANCER LETTERS, May 2000, Not refereed, Not invited - Fluorometric determination of aminopolycarboxylates using fluo-3
N Kawasaki; YC Lee; O Hashimoto; M Yamamoto; T Kawanishi; T Hayakawa
ANALYTICAL BIOCHEMISTRY, Jun. 1999, Refereed, Not invited - Fluorometric determination of aminopolycarboxylates using fluo-3
N Kawasaki; YC Lee; O Hashimoto; M Yamamoto; T Kawanishi; T Hayakawa
ANALYTICAL BIOCHEMISTRY, Jun. 1999, Not refereed, Not invited - Analysis of carbohydrate heterogeneity in a glycoprotein using liquid chromatography mass spectrometry and liquid chromatography with tandem mass spectrometry
N Kawasaki; M Ohta; S Hyuga; O Hashimoto; T Hayakawa
ANALYTICAL BIOCHEMISTRY, May 1999, Not refereed, Not invited - Analysis of carbohydrate heterogeneity in a glycoprotein using LC/MS and LC/MS/MS.
Kawasaki, N; Ohta, M; Hyuga, S; Hashimoto, O; Hayakawa, T
Anal. Biochem. 269: 297-303., 1999, Refereed, Not invited - The role of activin type I receptors in activin A-induced growth arrest and apoptosis in mouse B-cell hybridoma cells
O Hashimoto; K Yamato; T Koseki; M Ohguchi; A Ishisaki; H Shoji; T Nakamura; Y Hayashi; H Sugino; T Nishihara
CELLULAR SIGNALLING, Nov. 1998, Refereed, Not invited
Lead - Correlation between Bcl-X expression and B-cell hybridoma apoptosis induced by activin A
T Koseki; K Yamato; A Ishisaki; O Hashimoto; H Sugino; T Nishihara
CELLULAR SIGNALLING, Jul. 1998, Refereed, Not invited - Distribution of lectin binding in spermatogonia of Syrian hamsters in gonadally active and inactive states
A Suda; O Hashimoto; K Ogawa; M Kurohmaru; Y Hayashi
JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 1998, Refereed, Not invited - Distribution of lectin binding in spermatogonia of Syrian hamsters in gonadally active and inactive states
A Suda; O Hashimoto; K Ogawa; M Kurohmaru; Y Hayashi
JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 1998, Not refereed, Not invited - Study on evaluating methods for the quality control of glycoprotein products (II)—Erythropoietin products. Part 2.
Kawasaki, N; Ohta, M; Hyuga, S; Hashimoto, O; Hayakawa, T
Bull. Natl. Inst. Health Sci, 1998, Refereed, Not invited - Follistatin-like immunoreactivity in the cytoplasm and nucleus of spermatogenic cells in the rat
K Ogawa; O Hashimoto; M Kurohmaru; T Mizutani; H Sugino; Y Hayashi
EUROPEAN JOURNAL OF ENDOCRINOLOGY, Nov. 1997, Refereed, Not invited - Follistatin and its role as an activin-binding protein
Hiromu Sugino; Kishiko Sugino; Osamu Hashimoto; Hiroki Shoji; Takanori Nakamura
Journal of Medical Investigation, Aug. 1997, Not refereed, Not invited - A novel role of follistatin, an activin-binding protein, in the inhibition of activin action in rat pituitary cells - Endocytotic degradation of actin and its acceleration by follistatin associated with cell-surface heparan sulfate
O Hashimoto; T Nakamura; H Shoji; S Shimasaki; Y Hayashi; H Sugino
JOURNAL OF BIOLOGICAL CHEMISTRY, May 1997, Refereed, Not invited
Lead - cDNA cloning and expression of the Xenopus laevis vitellogenin receptor
K Okabayashi; H Shoji; T Nakamura; O Hashimoto; M Asashima; H Sugino
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 1996, Refereed, Not invited - Ultrastructure of cardiac myocyte in the Asian elephant (Elephas maximus)
H Endo; TK Yamada; N Suzuki; G Suwa; K Uetsuka; O Hashimoto; M Kurohmaru; Y Hayashi
JOURNAL OF VETERINARY MEDICAL SCIENCE, Dec. 1995, Refereed, Not invited - EFFECT OF EXTRACELLULAR-MATRIX ON 2 CELL-LINES ESTABLISHED FROM MONGOLIAN GERBILS (MERIONES-UNGUICULATUS) MALIGNANT-MELANOMA
O HASHIMOTO; K OGAWA; M KUROHMARU; Y HAYASHI
JOURNAL OF VETERINARY MEDICAL SCIENCE, Aug. 1995, Refereed, Not invited
Lead - CHARACTERIZATION OF CULTURED-CELLS DERIVED FROM MONGOLIAN GERBILS (MERIONES-UNGUICULATUS) ASCITIC MALIGNANT-MELANOMA
O HASHIMOTO; K MIYAMOTO; T MORITOMO; H SAITO; T WATANABE; K MOCHIZUKI
JOURNAL OF VETERINARY MEDICAL SCIENCE, Apr. 1993, Refereed, Not invited
Lead
MISC
- 妊娠期マウス膣粘液細胞ならびに分泌物の組織学的解析
杉山真言; 寺井菜々子; 深沢英恵; 小野久弥; 橋本統; 久留主志朗; 吉岡一機
日本獣医学会学術集会講演要旨集, 2021 - A novel hepatokine Activin E that accelerates fat combustion.
Osamu Hashimoto; Masayuki Funaba; Akira Kurisaki
医学のあゆみ, 14 Dec. 2019, Not refereed, Invited
Lead - マウス眼窩脂肪組織は発熱器官である
杉山 真言; 大関 貴大; 金田 規寿; 吉岡 一機; 舟場 正幸; 橋本 統
日本獣医学会学術集会講演要旨集, Aug. 2019, Not refereed, Not invited - 鉄負荷に対する肝細胞の応答
Chen Hsuan-Ju; 杉山 真言; 下河 史枝; 村上 賢; 橋本 統; 松井 徹; 舟場 正幸
日本栄養・食糧学会大会講演要旨集, Apr. 2019, Not refereed, Not invited - マウス眼窩脂肪組織の解析
杉山真言; 大関貴大; 金田規寿; 吉岡一機; 舟場正幸; 橋本 統
日本解剖学会 東北・北海道連合支部学術集会, Sep. 2018, Not refereed, Not invited - ヘプシジン転写調節機構について
金森耀平; 村上賢; 杉山真言; 橋本統; 松井徹; 舟場正幸
日本鉄バイオサイエンス学会学術集会プログラム・抄録集, Aug. 2018, Not refereed, Not invited - ウシ骨格筋におけるUcp1の発現
金森耀平; MABROUK Abd Eldaim; MABROUK Ab; Eldaim; 橋本統; 大津寄洋史; 山田知哉; 村上賢; 恩田賢; 佐藤礼一郎; 喬宇航; 友永省三; 松井徹; 舟場正幸
日本畜産学会大会講演要旨, 06 Sep. 2017, Not refereed, Not invited - β３アドレナリン受容体アゴニストが褐色脂肪組織および白色脂肪組織中の低分子代謝物質濃度に及ぼす影響
冨士本有佑; 橋本統; 友永省三; 松井徹; 舟場正幸
日本畜産学会第１２２回大会, Mar. 2017, Not refereed, Not invited - 炎症によるヘプシジン発現亢進の仲介因子アクチビンB
金森耀平; 杉山真言; 橋本統; 村上賢; 松井徹; 舟場正幸
日本栄養・食糧学会近畿支部大会および公開シンポジウム講演抄録集, 14 Sep. 2016, Not refereed, Not invited - ACTIVIN B PRODUCED BY SINUSOIDAL ENDOTHELIAL/KUPFFER CELLS IN RESPONSE TO INFLAMMATORY STIMULI INDUCES HEPCIDIN EXPRESSION THROUGH UNCANONICAL SIGNALING IN HEPATOCYTES
Y. Kanamori; M. Sugiyama; O. Hashimoto; M. Murakami; T. Matsui; M. Funaba
HAEMATOLOGICA, Jun. 2016, Not refereed, Not invited - Presence of brown/beige adipocytes in adipose tissues of fattening cattle and diet-related changes in their activity
舟場 正幸; 山田 知哉; 橋本 統; 村上 賢; 金森 燿平; 松井 徹
Proc Jpn Soc Anim Nutr Metab 60 (2): 85－97., 2016, Not refereed, Invited - Development of specific immunoassay systems for canine pituitary hormones using hetero-antibody fluor-immunoassay (FIA) method
Y. Hasegawa; O. Hashimoto
REPRODUCTION IN DOMESTIC ANIMALS, Aug. 2012, Not refereed, Not invited - ACTIVIN IN GLUCOSE METABOLISM
Osamu Hashimoto; Masayuki Funaba
ACTIVINS AND INHIBINS, 2011, Not refereed, Invited - アクチビンEの糖代謝への関与 肝臓におけるアクチビンE遺伝子の発現調節
橋本 統; 関山 一成; 松尾 剛; 長谷川 喜久
日本生化学会大会プログラム・講演要旨集, Sep. 2009 - 高インスリン感受性を示すアクチビン遺伝子改変マウスの解析
橋本 統; 関山 一成; 宇城 有紀; 長谷川 喜久
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Nov. 2007 - トランスジェニックマウスを用いたアクチビンEの機能解析
関山 一成; 橋本 統; 長谷川 喜久
日本獣医学会学術集会講演要旨集, Aug. 2006 - マウス肝臓におけるアクチビンβEサブユニットの局在性
宇城 有紀; 橋本 統; 山本 修; 関 真知; 吉岡 一機; 木崎 景一郎; 星 信彦; 長谷川 喜久
日本獣医学会学術集会講演要旨集, Sep. 2003, Not refereed, Not invited - The role of follistatin in activin signal transduction
Nakamura Takanori; Hashimoto Osamu; t; al
“Inhibin, Activin and Follistatin: Regulatory functions in system and cell biology, A Serono Symposia U.S.A”, (Aono, T.,Sugino, H. and Vale, W. W. eds.) Springer-Verlag, New York. pp. 264-276., 1997, Not refereed, Invited
Books and other publications
- 薬理学・毒性学実験
日本獣医薬理学・毒性学会; 大濱, 剛; 堀, 正敏; 室井, 喜景; 石塚, 真由美; 宇野, 泰広; 西村, 和彦, コラム10
文永堂出版, Mar. 2023
9784830032868 - 愛玩動物看護師必携テキスト
Joint work
Gakken, Jan. 2023
4780914671 - The role of follistatin in activin signal transduction.
Inhibin, activin and follistatin : Regulatory functions in system and cell biology, 1997, Not refereed
Lectures, oral presentations, etc.
Courses
Research Themes
- アクチビンE-KOマウスのNAFLD/NASHモデルとしての有用性
日本学術振興会, 科学研究費助成事業, Apr. 2022 - Mar. 2025
橋本 統 - Activin E-Knockout mice as a useful animal model of obesity/diabetes
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2019 - 31 Mar. 2022
Hashimoto Osamu - A novel physiological function of mast cells on tissue remodeling
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2011 - 31 Mar. 2014
KAWAMINAMI Mitsumori; YONEZAWA Tomohiro; HASHIMOTO Osamu; HASEGAWA Yoshihisa - Development of a lung regeneration method with lung precursor cells
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2011 - 31 Mar. 2014
Kurisaki Akira; Hashimoto Osamu - The role of activin E in metabolic syndrome and mood disorder
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2007 - 2008
HASHIMOTO Osamu - Isolation of Inhibin Receptor and Siginal Transuduction In TGF-β Superfamily
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2003 - 2005
HASEGAWA Yoshihisa; HASHIMOTO Osamu - インヒビンレセプターの同定とシグナル伝達に関する研究
日本学術振興会, 科学研究費助成事業, 2002 - 2004
長谷川 喜久; 橋本 統; 星 信彦 - 新規アクチビンβサブユニット遺伝子の機能解析
日本学術振興会, 科学研究費助成事業, 2001 - 2002
橋本 統 - Effects of fetal and neonatal exposure of male mice to diethylstilbestrol as endocrine disrupter on the reproductive and neuroendocrine system
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2000 - 2001
HOSHI Nobuhiko; SUGAWARA Teruo; HASHIMOTO Osamu; HASEGAWA Yoshihisa - メタボリック症候群に対するアクチビンEの有用性
- Study on Activins and Follistatins in Organogenesis
