NAKAYA Yuka

School of Dentistry Department of DentistrySenior Assistant Professor

Researcher Information

Field Of Study

  • Life sciences, Neuroscience - general

Career

  • Apr. 2023 - Present
    日本大学歯学部薬理学講座, 専任講師
  • Mar. 2019 - Mar. 2023
    日本大学歯学部薬理学講座, 助教
  • Apr. 2017 - Mar. 2019
    日本大学歯学部薬理学講座, ポスドク
  • Apr. 2016 - Mar. 2017
    Kanagawa Dental College, 小児歯科, 医員
  • Apr. 2011 - Mar. 2012
    日本大学歯学部付属歯科病院, 研修診療部

Educational Background

  • Apr. 2012 - Mar. 2016
    Nihon University, 大学院, 歯学研究科(口腔診断学講座)
  • Apr. 2005 - Mar. 2011
    Nihon University, School of Dentistry, Department of Dentistry
Research activity information

Award

  • 2024
    歯科基礎医学会, 第36回歯科基礎医学会奨励賞

Paper

  • Trigeminal ganglion-trigeminal spinal subnucleus oralis pathway contributes to orofacial neuropathic pain.
    Yurika Ide; Koichi Iwata; Yoshinori Hayashi; Suzuro Hitomi; Yue Zhou; Yuka Nakaya; Shiori Kawasaki; Masayuki Kobayashi; Barry J Sessle; Shinji Okada; Toshimitsu Iinuma; Masamichi Shinoda
    Pain, Mar. 2026
  • Intracellular mechanisms underlying modulation of inhibitory synaptic transmission by appetite-related peptides in the insular cortex.
    Yuka Nakaya; Masayuki Kobayashi
    Journal of oral biosciences, Feb. 2026
  • Synaptic function of descending projections from the insular cortex to the nucleus solitary tract in the rat
    Ami Wakabayashi; Yuka Nakaya; Kiyofumi Yamamoto; Yumi Tsutsumi; Fumihiko Sato; Atsushi Yoshida; Takashi Kikuiri; Masayuki Kobayashi
    Brain Research, Jan. 2026
  • Descending projections from the insular cortex to the lateral parabrachial nucleus facilitate nocifensive behaviors in rats
    Yuka Nakaya; Kensuke Hirose; Kouhei Kitano; Gege Zhao; Asuka Kobayashi; Hironobu Osaki; Masayuki Kobayashi
    Pain, Aug. 2025
  • Opioidergic activation of the descending pain inhibitory system underlies placebo analgesia.
    Hiroyuki Neyama; Yuping Wu; Yuka Nakaya; Shigeki Kato; Tomoko Shimizu; Tsuyoshi Tahara; Mika Shigeta; Michiko Inoue; Kazunari Miyamichi; Natsuki Matsushita; Tomoji Mashimo; Yoshiki Miyasaka; Yi Dai; Koichi Noguchi; Yasuyoshi Watanabe; Masayuki Kobayashi; Kazuto Kobayashi; Yilong Cui
    Science advances, Jan. 2025
  • Functional roles of descending projections from the cerebral cortex to the trigeminal spinal subnucleus caudalis in orofacial nociceptive information processing
    Masayuki Kobayashi; Yuka Nakaya; Satomi Kobayashi
    Journal of Oral Biosciences, May 2024
  • インスリンの島皮質抑制性シナプス伝達増強に対する薬理学的アプローチ
    中谷 有香; 小林 真之
    日本口腔内科学会雑誌, Dec. 2023
  • Insulin potentiates inhibitory synaptic currents between fast-spiking and pyramidal neurons in the rat insular cortex.
    Yuka Nakaya; Satoshi Kosukegawa; Satomi Kobayashi; Kensuke Hirose; Kouhei Kitano; Kotoe Mayahara; Hiroki Takei; Mitsuru Motoyoshi; Masayuki Kobayashi
    Neuropharmacology, Nov. 2023
  • Insular cortical descending projections facilitate neuronal responses to noxious but not innoxious stimulation in rat trigeminal spinal subnucleus caudalis.
    Yuka Nakaya; Koichi Iwata; Masayuki Kobayashi
    Brain research, Apr. 2023
  • Insulin facilitates synaptic transmission via gap junctions between fast-spiking interneurons in the rat insular cortex.
    Satoshi Kosukegawa; Yuka Nakaya; Satomi Kobayashi; Kohei Kitano; Sachie Matsumura; Shohei Ogisawa; Manabu Zama; Mitsuru Motoyoshi; Masayuki Kobayashi
    Journal of oral science, Mar. 2023
  • Descending projections from the insular cortex to the trigeminal spinal subnucleus caudalis facilitate excitatory outputs to the parabrachial nucleus in rats.
    Yuka Nakaya; Kiyofumi Yamamoto; Masayuki Kobayashi
    Pain, Mar. 2023
  • Neural Subtype-dependent Cholinergic Modulation of Neural Activities by Activation of Muscarinic 2 Receptors and G Protein-activated Inwardly Rectifying Potassium Channel in Rat Periaqueductal Gray Neurons.
    Shiori Sugawara; Yuka Nakaya; Sachie Matsumura; Kensuke Hirose; Yasuhiko Saito; Ryosuke Kaneko; Masayuki Kobayashi
    Neuroscience, Dec. 2022
  • Synchronous inhibitory synaptic inputs to layer II/III pyramidal neurons in the murine barrel cortex
    Kiyofumi Yamamoto; Yuka Nakaya; Shiori Sugawara; Masayuki Kobayashi
    Brain Research, Dec. 2021
  • Differential regulation of medium spiny and cholinergic neurons in the nucleus accumbens core by the insular and medial prefrontal cortices in the rat.
    Kensuke Hirose; Yuka Nakaya; Kohei Kitano; Yasuhiko Saito; Ryosuke Kaneko; Yuchio Yanagawa; Kiyofumi Yamamoto; Tetsuo Shirakawa; Masayuki Kobayashi
    Pflugers Archiv : European journal of physiology, Dec. 2021
  • Presynaptic NK1 Receptor Activation by Substance P Suppresses EPSCs via Nitric Oxide Synthesis in the Rat Insular Cortex.
    Sachie Matsumura; Kiyofumi Yamamoto; Yuka Nakaya; Kazunori O'Hashi; Keisuke Kaneko; Hiroki Takei; Hiromasa Tsuda; Tetsuo Shirakawa; Masayuki Kobayashi
    Neuroscience, Feb. 2021
  • Anatomical aspects of corticotrigeminal projections to the medullary dorsal horn.
    Masayuki Kobayashi; Yuka Nakaya
    Journal of oral science, Mar. 2020
  • Involvement of TRPV4 ionotropic channel in tongue mechanical hypersensitivity in dry-tongue rats
    Jui Yen Chen; Asako Kubo; Masamichi Shinoda; Yuka Nakaya; Akiko Okada-Ogawa; Yoshiki Imamura; Koichi Iwata
    JOS, 2019, Refereed, Not invited
  • Preceding Administration of Minocycline Suppresses Plastic Changes in Cortical Excitatory Propagation in the Model Rat With Partial Infraorbital Nerve Ligation.
    Manabu Zama; Satoshi Fujita; Yuka Nakaya; Morio Tonogi; Masayuki Kobayashi
    Frontiers in neurology, 2019
  • ERK-GluR1 phosphorylation in trigeminal spinal subnucleus caudalis neurons is involved in pain associated with dry tongue.
    Yuka Nakaya; Yoshiyuki Tsuboi; Akiko Okada-Ogawa; Masamichi Shinoda; Asako Kubo; Jui Yen Chen; Noboru Noma; Dulguun Batbold; Yoshiki Imamura; Barry J Sessle; Koichi Iwata
    Molecular pain, 2016
  • Headache attributed to temporomandibular disorders and masticatory myofascial pain.
    Kazuhiko Hara; Takahiro Shinozaki; Akiko Okada-Ogawa; Yumiko Matsukawa; Ko Dezawa; Yuka Nakaya; Jui-Yen Chen; Noboru Noma; Shunichi Oka; Koichi Iwata; Yoshiki Imamura
    Journal of oral science, 2016
  • p38 phosphorylation in medullary microglia mediates ectopic orofacial inflammatory pain in rats.
    Masaaki Kiyomoto; Masamichi Shinoda; Kuniya Honda; Yuka Nakaya; Ko Dezawa; Ayano Katagiri; Satoshi Kamakura; Tomio Inoue; Koichi Iwata
    Molecular pain, Aug. 2015
  • Involvement of medullary GABAergic system in extraterritorial neuropathic pain mechanisms associated with inferior alveolar nerve transection.
    Akiko Okada-Ogawa; Yuka Nakaya; Yoshiki Imamura; Masayuki Kobayashi; Masamichi Shinoda; Kozue Kita; Barry J Sessle; Koichi Iwata
    Experimental neurology, May 2015
  • Involvement of Trigeminal Transition Zone and Laminated Subnucleus Caudalis in Masseter Muscle Hypersensitivity Associated with Tooth Inflammation
    Kohei Shimizu; Kunihito Matsumoto; Noboru Noma; Shingo Matsuura; Kinuyo Ohara; Hiroki Komiya; Tetsuro Watase; Bunnai Ogiso; Yoshiyuki Tsuboi; Masamichi Shinoda; Keisuke Hatori; Yuka Nakaya; Koichi Iwata
    PLOS ONE, Oct. 2014, Refereed, Not invited
  • Interaction of IL-1 beta and P2X(3) Receptor in Pathologic Masseter Muscle Pain
    N. Noma; M. Shinoda; K. Honda; M. Kiyomoto; K. Dezawa; Y. Nakaya; O. Komiyama; Y. Imamura; K. Iwata
    JOURNAL OF DENTAL RESEARCH, May 2013, Refereed, Not invited
  • Involvement of GABAergic interneurons in orofacial neuropathic pain following trigeminal nerve transection in rats
    OKADA OGAWA Akiko; SUZUKI Ikuko; NAKAYA Yuka; KOBAYASHI Masayuki; EBIHARA Katsuko; IMAMURA Yoshiki; IWATA Koichi
    PAIN RESEARCH, Mar. 2013
  • Stellate ganglion block as an early intervention in sympathetically maintained headache and orofacial pain caused by temporal arteritis.
    Noboru Noma; Hiroshi Kamo; Yuka Nakaya; Ko Dezawa; Andrew Young; Junad Khan; Yoshiki Imamura
    Pain medicine (Malden, Mass.), Mar. 2013

Research Themes

  • 島皮質から三叉神経脊髄路核尾側亜核への下行性投射の慢性痛に対する役割の解明
    日本学術振興会, 科学研究費助成事業, 01 Apr. 2023 - 31 Mar. 2026
    中谷 有香; 小林 真之; 加藤 成樹
  • Exploration of insulocortical neurons relating to memory consolication of orofacial pain
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 30 Jun. 2023 - 31 Mar. 2025
    小林 真之; 尾崎 弘展; 中谷 有香; 加藤 成樹
  • Regulatroy mechanisms of hyperexcitation of insulocortical circuit of the model with neuropathic pain by chemical genetics
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2022 - 31 Mar. 2025
    小林 真之; 藤田 智史; 山本 清文; 中谷 有香; 加藤 成樹
  • The study using chemical genetics to reveal regulation mechanisms of insulocortical hyperactivities in the neuropathic pain model
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2022 - 31 Mar. 2025
    小林 真之; 藤田 智史; 山本 清文; 中谷 有香; 加藤 成樹
  • 光遺伝学的手法による島皮質から腕傍核への投射経路の機能解明
    日本学術振興会, 科学研究費助成事業, 01 Apr. 2021 - 31 Mar. 2023
    中谷 有香
  • 味覚の臨界期を探るためのGRINレンズによる覚醒マウスの脳内イメージング法の確立
    日本学術振興会, 科学研究費助成事業, 01 Apr. 2020 - 31 Mar. 2023
    武井 浩樹; 藤田 智史; 山本 清文; 中谷 有香
  • Mechanisms of insulocortical inhibitory synaptic transmission plasticity that regulates neuropathic pain
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2019 - 31 Mar. 2022
    KOBAYASHI Masayuki
  • Optogenetic strategies to investigate profiles of excitatory projection from the insular cortex to trigeminal spinal subnucleus caudalis
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2018 - 31 Mar. 2020
    NAKAYA Yuka