yamazaki jun
| College of Bioresource Sciences Department of Veterinary Medicine | Professor |
Researcher Information
Research Keyword
Field Of Study
Career
- Apr. 2018 - Present
Department of Veterinary Medicine, Nihon University College of Bioresource Sciences, Laboratory of Veterinary Pharmacology, Professor - Apr. 2015 - Mar. 2018
Fukuoka Dental College, Division of Biomedical Sciences, Chair of the Division - Jul. 2009 - Mar. 2018
Fukuoka Dental College, Department of Physiological Science & Molecular Biology, Professor - Apr. 2011 - Mar. 2015
Fukuoka Dental College, Department of Physiological Science & Molecular Biology, Chair of the Department - Apr. 1998 - Jun. 2009
Fukuoka Dental College, Department of Physiological Science & Molecular Biology (Former Dept. Pharmacol.), Associate Professor - Sep. 1995 - Apr. 1998
University of Nevada School of Medicine, USA, Dept. Physiol. and Cell Biol., Research Assistant Professor - Apr. 1993 - Apr. 1998
Faculty of Pharmaceutical Sciences, The University of Tokyo, Department of Toxicology and Pharmacology, Assistant Professor - Apr. 1990 - Mar. 1993
Faculty of Pharmaceutical Sciences, Department of Toxicology and Pharmacology, Research Assistant
Educational Background
- Apr. 1987 - Mar. 1990
The University of Tokyo, Graduate School of Pharmaceutical Sciences, Ph.D Course - Apr. 1985 - Mar. 1987
The University of Tokyo, Graduate School of Pharmaceutical Sciences, Master's Course - Apr. 1983 - Mar. 1985
The University of Tokyo, Faculty of Pharmaceutical Sciences, 薬学科 - Apr. 1981 - Mar. 1983
The University of Tokyo, Komaba, College of Arts and Sciences, 理科II類
Research activity information
Award
Paper
- Canine, mouse, and human TRPA1 channels show different sensitivity to menthol or cold stimulation
Yamaguchi T; Uchida K; Yamazaki J
J. Vet. Med. Sci., Dec. 2023, Refereed, Not invited
Last - Involvement of pore helix in voltage-dependent inactivation of TRPM5 channel.
Uchida K.; Kita T.; Hatta M.; Itoh S.G.; Okumura H.; Tominaga M.; Yamazaki J.
Heliyon, 2021, Refereed, Not invited
Last - Non-transcriptional and translational function of canonical NF-κB signaling in activating ERK1/2 in IL-1β-induced COX-2 expression in synovial fibroblasts.
Nakano R.; Kitanaka T.; Namba S.; Kitanaka N.; Suwabe Y.; Konno T.; Yamazaki J.; Nakayama T.; Sugiya H.
Front. Immunol., 2020, Refereed, Not invited - Analysis of the Influence of Porphyromononas gingivalis on the Human Oral Mucosa with a Three-demensional Construct Model
Ryu T; Uchida K.; Okamura K.; Hatta M.; Yamazaki J.; Sakagami R.
The Japanese Journal of Conservative Dentistry, 2020, Refereed, Not invited - FK506 (tacrolimus) causes pain sensation through the activation of transient receptor potential ankyrin 1 (TRPA1) channels
Kita T.; Uchida K.; Kato K.; Suzuki Y.; Tominaga M.; Yamazaki J.
J Physiol Sci., 2019, Refereed, Not invited
Last - Identification and classification of a new TRPM3 variant (γ subtype)
Uchida K.; Fukuta N.; Yamazaki J.; Tominaga M.
J Physiol Sci., 2019, Refereed, Not invited - Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line
Mitsutoki Hatta; Yuki Miyake; Kunitoshi Uchida; Jun Yamazaki
Biochemical and Biophysical Research Communications, Feb. 2018, Refereed, Not invited
Last - Role of thermo-sensitive transient receptor potential channels in brown adipose tissue
Uchida K; Sun W; Yamazaki J; Tominaga M
Biol. Pharm. Bull., 2018, Refereed, Invited - TRPV2 channel inhibitors attenuate fibroblast differentiation and contraction mediated by keratinocyte-derived TGF-beta1 in an in vitro wound healing model of rats.
Ishii T.; Uchida K.; Hata S.; Hatta M.; Kita T.; Miyake Y.; Okamura K.; Tamaoki S.; Ishikawa H.; Yamazaki J.
J. Dermatol. Sci., 2018, Refereed, Not invited
Last - Peptidylarginine deiminase is involved in maintaining the cornified oral mucosa of rats.
Arita S.; Hatta M.; Uchida K.; Kita T.; Okamura K.; Ryu T.; Murakami H.; Sakagami R.; Yamazaki J.
J. Periodont. Res., 2018, Refereed, Not invited
Last - PLXNA2 identified as a candidate gene by genome-wideassociation analysis for mandibular prognathism in human chondrocytes
Kajii T.S.; Oka A.; Hatta M.; Yamazaki J.; Yamashita J.; Iida J.
Biomed. Rep., 2018, Refereed, Not invited - 10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, enhances energy metabolism by activation of TRPV1
Minji Kim; Tomoya Furuzono; Kanae Yamakuni; Yongjia Li; Young-Il Kim; Haruya Takahashi; Ryuji Ohue-Kitano; Huei-Fen Jheng; Nobuyuki Takahashi; Yuriko Kano; Rina Yu; Shigenobu Kishino; Jun Ogawa; Kunitoshi Uchida; Jun Yamazaki; Makoto Tominaga; Teruo Kawada; Tsuyoshi Goto
FASEB JOURNAL, Nov. 2017, Refereed, Not invited - Characteristics of TMEM16A (anoctamin 1) activation induced by P2Y receptors stimulation in rat small pulmonary artery smooth muscle cells
Kenichi Kato; Kunitoshi Uchida; Mitsutoki Hatta; Jun Yamazaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017
Last - The involvement of TRPM2 channel in insulin secretion and the development of diabetes
Kunitoshi Uchida; Jun Yamazaki; Makoto Tominaga
JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017, Refereed, Not invited - Involvement of thermo-TRP channels in energy metabolism.
Uchida, K; Dezaki, K; Yoneshiro, T; Watanabe, T; Yamazaki, J; Saito, M; Yada, T; Tominaga, M; Iwasaki, Y
J Physiol Sci., 2017, Refereed, Invited - Differentiation of rat dermal mesenchymal cells and calcification in three-dimensional cultures
Taiki Suyama; Mitsutoki Hatta; Shozaburo Hata; Hiroyuki Ishikawa; Jun Yamazaki
TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Oct. 2016, Refereed, Not invited
Last - Accelerated Osteogenic Differentiation and Bone Formation on Zirconia with Surface Grooves Created with Fiber Laser Irradiation
Yusuke Taniguchi; Kae Kakura; Katsuki Yamamoto; Hirofumi Kido; Jun Yamazaki
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Oct. 2016, Refereed, Not invited
Last - 上皮細胞のイオン輸送と分化に関与したカルシウム活性化クロライドチャネル関連分子の機能発現．カルシウムシグナル制御研究から見えてきた内分泌・免疫系疾患の新たな創薬標的．
山﨑 純
薬学雑誌, 2016, Refereed, Invited
Lead - Mechanistic insight into the aberrant silencing of the keratin 13 gene in oral squamous cell carcinoma cells.
Hatta M; Arita S; Yamazaki J
J. Oral Biosci., 2016, Refereed, Not invited
Last - 3-Deazaneplanocin A suppresses aggressive phenotype-related gene expression in an oral squamous cell carcinoma cell line
Mitsutoki Hatta; Kaori Naganuma; Kenichi Kato; Jun Yamazaki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2015, Refereed, Not invited
Last - Estimated molecular structure of a carbon nanotube molecular heater based on binding properties to a target protein
Minoru Kawaguchi; Jun Yamazaki
JOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALS, Oct. 2015, Refereed, Not invited
Last - NF-kappa B-regulated transcriptional control of CLCA in a differentiated mouse keratinocyte line
Ryo Hiromatsu; Mitsutoki Hatta; Kazuhiko Okamura; Ryuji Sakagami; Jun Yamazaki
JOURNAL OF DERMATOLOGICAL SCIENCE, Jun. 2015, Refereed, Not invited
Corresponding - Integrin alpha 6 beta 4 and TRPV1 channel coordinately regulate directional keratinocyte migration
Ayako Miyazaki; Tsuyako Ohkubo; Mitsutoki Hatta; Hiroyuki Ishikawa; Jun Yamazaki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 2015, Refereed, Not invited
Last - Epigenetic alterations of the keratin 13 gene in oral squamous cell carcinoma
Kaori Naganuma; Mitsutoki Hatta; Tetsuro Ikebe; Jun Yamazaki
BMC CANCER, Dec. 2014, Refereed, Not invited
Last - Association of caspase-14 and filaggrin expression with keratinization of the oral mucosa and reconstruction culture rat models
H. Murakami; K. Okamura; S. Aoki; R. Sakagami; J. Yamazaki
JOURNAL OF PERIODONTAL RESEARCH, Dec. 2014, Refereed, Not invited
Corresponding - Proteolytic and Non-proteolytic Activation of Keratinocyte-Derived Latent TGF-beta 1 Induces Fibroblast Differentiation in a Wound-Healing Model Using Rat Skin
Shozaburo Hata; Kazuhiko Okamura; Mitsutoki Hatta; Hiroyuki Ishikawa; Jun Yamazaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, Feb. 2014, Refereed, Not invited
Corresponding - Involvement of IP3-receptor activation in endothelin-1-induced Ca2+ influx in rat pulmonary small artery
K. Kato; K. Okamura; M. Hatta; H. Morita; S. Kajioka; S. Naito; J. Yamazaki
EUROPEAN JOURNAL OF PHARMACOLOGY, Nov. 2013, Refereed, Not invited
Last - CLCA Splicing Isoform Associated with Adhesion through beta(1)-Integrin and Its Scaffolding Protein SPECIFIC EXPRESSION IN UNDIFFERENTIATED EPITHELIAL CELLS
Jun Yamazaki; Kazuhiko Okamura; Kiyoko Uehara; Mitsutoki Hatta
JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2013, Refereed, Not invited
Lead - 高齢者歯科外来における疾患及び服薬に関する実態調査．
牧野路子; 内藤徹; 円林彩子; 中佳香; 野田佐織; 竹内哲二; 内田初美; 村上早苗; 大星博明; 山﨑純; 廣藤卓雄
福岡歯科大学学会雑誌, 2013, Refereed, Not invited - T-type voltage-activated calcium channel Ca(v)3.1, but not Ca(v)3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells
Tsuyako Ohkubo; Jun Yamazaki
INTERNATIONAL JOURNAL OF ONCOLOGY, Jul. 2012, Refereed, Not invited
Last - Preparation and binding study of a complex made of DNA-treated single-walled carbon nanotubes and antibody for specific delivery of a "molecular heater" platform
Minoru Kawaguchi; Jun Yamazaki; Jun Ohno; Tadao Fukushima
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2012, Refereed, Not invited - Blockade of TRPM8 activity reduces invasive potential of oral squamous carcinoma cell lines
Okamoto; Y.; Ohkubo; T.; Ikebe; T.; Yamazaki; J.
Int. J Oncol., 2012, Refereed, Not invited
Corresponding - Dual signaling pathways of arterial constriction by extracellular uridine 5′-triphosphate in the rat.
Sugihara, M; Morita, H; Matsuda, M; Umebayashi, H; Kajioka, S; Ito, S; Nishida, M; Inoue, R; Futatsuki, T; Yamazaki, J; Mori, Y; Inoue, R; Ito, Y; Abe, K; Hirata, M
J. Pharmacol. Sci., 2011, Refereed, Not invited - Inhibition of T-type calcium channels and hydrogen sulfide-forming enzyme reverses paclitaxel-evoked neuropathic hyperalgesia in rats.
Okubo. K; Takahashi, T; Sekiguchi, F; Kanaoka, D; Matsunami, M; Ohkubo, T; Yamazaki, J; Fukushima, N; Yoshida, S; Kawabata, A
Neuroscience, 2011, Refereed, Not invited - Dispersion stability and exothermal properties of DNA-functionalized single-walled carbon nanotubes.
Kawaguchi; M.; Ohno; J.; Irie; A.; Fukushima; T.; Yamazaki; J.; Nakashima; N.
Int. J. Nanomed., 2011, Refereed, Not invited - Specific expression of salivary maxi-K channel variant is augmented in diabetic mice
Kazuhiko Okamura; Kenichi Kato; Ryuji Uchida; Tsuyako Ohkubo; Kunihisa Taniguchi; Jun Yamazaki
ARCHIVES OF ORAL BIOLOGY, Nov. 2010, Refereed, Not invited
Corresponding - Tarantula Toxin ProTx-I Differentiates Between Human T-type Voltage-Gated Ca2+ Channels Ca(v)3.1 and Ca(v)3.2
Tsuyako Ohkubo; Jun Yamazaki; Kenji Kitamura
JOURNAL OF PHARMACOLOGICAL SCIENCES, Apr. 2010, Refereed, Not invited - 上皮細胞におけるCl- チャネルとCLCAの機能
山﨑 純
福岡歯科大学雑誌, 2010, Refereed, Invited
Lead - Giant cell fibroma of the tongue: report of a case showing unique S-100 and HLA-DR immunolocalization and literature review.
Okamura, K; Ohno, J; Iwahashi, T; Enoki, N; Taniguchi, K; Yamazaki,J
Oral Med.Pathol., 2009, Refereed, Not invited
Last - Involvement of apical P2Y(2) receptor-regulated CFTR activity in muscarinic stimulation of Cl- reabsorption in rat submandibular gland
Kazunari Ishibashi; Kazuhiko Okamura; Jun Yamazaki
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, May 2008, Refereed, Not invited
Corresponding - Roles of CLCA and CFTR in electrolyte re-absorption from rat saliva
K. Ishibashi; J. Yamazaki; K. Okamura; Y. Teng; K. Kitamura; K. Abe
JOURNAL OF DENTAL RESEARCH, Dec. 2006, Refereed, Not invited - Characterization of CLCA protein expressed in ductal cells of rat salivary glands
J Yamazaki; K Okamura; K Ishibashi; K Kitamura
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, Sep. 2005, Refereed, Not invited
Lead - Regulation of RecA protein binding to DNA by opposing effects of ATP and ADP on inter-domain contacts: Analysis by urea-induced unfolding of wildtype and C-terminal truncated RecA
J Yamazaki; T Horii; M Sekiguchi; M Takahashi
JOURNAL OF MOLECULAR BIOLOGY, May 2003, Refereed, Not invited
Lead - Characterization of Ca2+ current inhibition by cilnidipine using a beta-subunit antisense oligonucleotide.
Uchida, R; Yamazaki, J; Kitamura K
Eur. J. Pharmacol., 2003, Refereed - Intercellular electrical coupling in vascular cells present in rat intact cerebral arterioles
J Yamazaki; K Kitamura
JOURNAL OF VASCULAR RESEARCH, Jan. 2003, Refereed, Not invited
Lead - Differences in protective profiles of diltiazem isomers in ischemic and reperfused guinea pig hearts
Sato R; Sakamoto K; Yamazaki J; Nagao T
European Journal of Pharmacology, 2002, Refereed, Not invited - State-dependent inhibition of L-type Ca2+ channels in A7r5 cells by cilnidipine and its derivatives
R Uchida; J Yamazaki; S Ozeki; K Kitamura
JAPANESE JOURNAL OF PHARMACOLOGY, Mar. 2001, Refereed, Not invited - Chloride channels and their functional roles in smooth muscle tone in the vasculature.
Kitamura, K; Yamazaki, J
Jpn. J. Pharmacol., 2001, Refereed, Not invited
Last - Diltiazem ameliorates contractile dysfunction without shortening of action potential duration in ischemic heart of anesthetized dogs.
Hamada, K; Yamazaki, J; Nagao, T
Jpn. J. Pharmacol., 2001, Refereed - Cell-to-cell communication via nitric oxide modulation of oscillatory Cl- currents in rat intact cerebral arterioles
Yamazaki; J. and Kitamura
J. Physiol. (Lond), 2001, Refereed, Not invited
Lead - Anion transport in heart.
Hume, J.R; Duan, D; Collier, M.L; Yamazaki, J; Horowitz B
Physiol. Rev., 2000, Refereed, Not invited - Lysophosphatidylcholine triggers intracellular calcium release and activation of non-selective cation channels in renal arterial smooth muscle cells.
Jabr, R.I; Yamazaki, J; Hume, J.R
Pflügers Archiv., 2000, Refereed, Not invited - Presence and possible role of spliced isoform of P2X1 receptor in rat vascular smooth muscle cells.
Ohkubo, T; Yamazaki, J; Nakashima, Y; Kitamura, K
Pflügers Archiv., 2000, Refereed, Not invited - Purinoceptor-coupled Cl- channels in mouse heart: a novel, alternative pathway for CFTR regulation
DY Duan; LY Ye; F Britton; LJ Miller; J Yamazaki; B Horowitz; Hume, JR
JOURNAL OF PHYSIOLOGY-LONDON, Nov. 1999, Refereed, Not invited - Temporal differences in actions of calcium channel blockers on K+ accumulation, cardiac function, and high-energy phosphate levels in ischemic guinea pig hearts
R Sato; J Yamazaki; T Nagao
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, May 1999, Refereed, Not invited - Regulation of recombinant cardiac CFTR chloride channels by protein kinase C in Xenopus oocytes
Yamazaki; J.; Britton; F.; Collier; M.L.; Horowitz; B.; Hume J.R.
Biophysical Journal, 1999, Refereed, Not invited
Lead - Shortening of action potential duration is not prerequisite for cardiac protection by ischemic preconditioning or a K-ATP channel opener
K Hamada; J Yamazaki; T Nagao
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Jul. 1998, Refereed, Not invited - Direct activation of endothelial NO pathway by Ba(2+) in canine coronary artery
J Yamazaki; K Sato; F Ohara; T Nagao
BRITISH JOURNAL OF PHARMACOLOGY, Jul. 1998, Refereed, Not invited
Lead - Shortening of monophasic action potential duration during hyperkalemia and myocardial ischemia in anesthetized dogs.
Hamada, K; Yamazaki, J; Nagao, T
Jpn. J. Pharmacol., 1998, Refereed, Not invited - Real time measurement of nitric oxide released from cultured endothelial cells.
Kurumatani, H; Kikuchi, K; Nagano, T; Hirobe, M; Yamazaki, J; Nagao, T
Biol. Pharm. Bull., 1998, Refereed, Not invited - 5-Hydroxydecanoate selectively reduces the initial increase in extracellular K+ in ischemic guinea-pig heart
Sakamoto; K.; Yamazaki; J.; Nagao; T.
Eur. J. Pharmacol., 1998, Refereed, Not invited - Modulatory role of endothelial calcium level in vascular tension of canine depolarized coronary arteries
Sato; K.; Yamazaki; J.; Nagao; T.
Am. J. Physiol., 1998, Refereed, Not invited - Functional and molecular expression of volume-regulated chloride channels in canine vascular smooth muscle cells
Yamazaki; J.; Duan; D.; Janiak; R.; Kuenzli; K.; Horowitz; B.; Hume; J.R.
J. Physiol. (Lond. ), 1998, Refereed, Not invited
Lead - Diltiazem inhibits the late increase in extracellular potassium by maintaining glycolytic ATP synthesis during myocardial ischemia
Sakamoto; K.; Yamazaki; J.; Nagao; T.
J. Cardiovasc. Pharmacol., 1997, Refereed, Not invited - Inhibitory effects of glibenclamide on cystic fibrosis transmembrane regulator, swelling-activated and calcium-activated chloride channels in mammalian cardiac myocytes
Yamazaki; J.; Hume; J.R.
Circ. Res., 1997, Refereed, Not invited
Lead - Flow dependence of nitric oxide-mediated pressure change in rat mesenteric beds with different tonus.
Kusayama, T; Yamazaki, J; Nagao, T
Eur. J. Pharmacol., 1996, Refereed, Not invited - Barium activates rat cerebeller nitric oxide synthase
Yamazaki; J.; Urushidani; T.; Nagao; T.
Jpn. J. Pharmacol., 1996, Refereed, Not invited
Lead - Contractions and relaxations accompanied by endothelial nitric oxide production induced in the porcine coronary artery by Ca2+, Ba2+ and Sr2+
Koji Ohashi; Jun Yamazaki; Taku Nagao
European Journal of Pharmacology, Oct. 1995, Refereed, Not invited - Barium and strontium can substitute for calcium in nitric oxide production in endothelium of canine coronary arteries.
Yamazaki, J; Ohara, F; Harada, Y; Nagao, T
Jpn. J. Pharmacol., 1995, Refereed, Not invited
Lead - Differential effects of beta1-agonist stimulation on epi- and endocardial oxygen tention in anesthetized dogs.
Tagami, H; Yamazaki, J; Nagao, T
Biol. Pharm. Bull., 1995, Refereed, Not invited - Hemodynamic and coronary vasodilative properites of a selective and full beta1-adrenoceptor agonist, T-0509, in comparison with isoproterenol in anesthetized dogs.
Yamazaki, J; Sugimoto, T; Yabana, H; Nagao,T
J. Cardiovasc. Pharmacol., 1994, Refereed, Not invited
Lead - 5-HT2/5-HT1C receptor-mediated facilitatory action on unit activity of the ventral horn cells in rat spinal cord slices.
Yamazaki, J; Fukuda, H; Nagao, T; Ono, H
Eur. J. Pharmacol., 1992, Refereed, Not invited
Lead - Stimulatory and inhibitory effects of serotonergic hallucinogens on spinal monosynaptic and polysynaptic reflex pathways in the rats.
Yamazaki, J; Ono, H; Nagao, T
Neuropharmacology, 1992, Refereed
Lead - NG-Monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats.
Yamazaki, J; Fujita, N; Nagao, T
J. Pharmacol. Exp. Ther., 1991, Refereed, Not invited
Lead - Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drigs in cultured chick spinal neurons.
Yamazaki, J; Matsumoto, K; Ono, H; Fukuda, H
Comp. Biochem. Physiol. C, 1989, Refereed, Not invited
Lead - Actions of avermectins on cultured neurons.
Matsumoto, K; Yamazaki, J; Fukuda, H
Gen. Pharmacol., 1988, Refereed, Not invited - Carbacyclin 誘導体 Sodium (1S,2S,3R,5S,7E)-2[(1E,3S,5R)-5,9-dimethyl-3-hydroxy-1,8-decadienyl]-3-hydroxy-7-(4-carboxylactobutylidene)-[3.3.0]-bicyclooctane (CS-570)の中枢神経系および運動系に対する作用.
福田秀臣; 小野秀樹; 松本欣三; 鈴木岳之; 中村 健; 森 智博; 永野伸郎; 佐藤光利; 田辺光男; 三島昭宏; 山﨑 純
応用薬理, 1986, Refereed, Not invited - The actions of ivermectin on cultured chick spinal cord neurons.
Matsumoto, K; Yamazaki, J; Kasuya, M; Fukuda, H
Neuroscience Lett., 1986, Refereed, Not invited
MISC
- Porphyromonas gingivalisがヒト口腔粘膜上皮細胞機能に与える影響
笠 孝成; 内田 邦敏; 有田 晴一; 有田 陽一; 河原 ゆり; 高瀬 稔; 吉永 泰周; 八田 光世; 山崎 純; 坂上 竜資
日本歯周病学会会誌, Oct. 2019 - ラット皮膚創傷治癒モデルの瘢痕収縮に対するTRPチャネル阻害薬の効果
石井 太郎; 秦 省三郎; 三宅 佑宜; 八田 光世; 内田 邦敏; 玉置 幸雄; 石川 博之; 山崎 純
福岡歯科大学学会雑誌, Jun. 2018 - Comparison of caspase-14 and filaggrin expressions between cornified and non-cornified stratified epithelia
Hiroshi Murakami; Kazuhiko Okamura; Mitsutoki Hatta; Sakagami Ryuji; Jun Yamazaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013, Not refereed, Not invited - CLCA isoforms and structural proteins differentially expressed in a reconstruction model derived from rat skin
Jun Yamazaki; Kazuhiko Okamura; Hiroshi Murakami; Shozaburo Hata; Ryo Hiromatsu; Ayako Miyazaki; Tsuyako Ohkubo; Mitsutoki Hatta
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012, Not refereed, Not invited - Transformation from fibroblast to myofibroblast is regulated by TGF beta and mechanical tension in a rat skin reconstruction model
Shozaburo Hata; Kazuhiko Okamura; Hiroyuki Ishikawa; Jun Yamazaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012, Not refereed, Not invited - Expression of caspase-14 in stratified and cornified epithelium in a rat oral mucosal reconstruction model
Hiroshi Murakami; Kazuhiko Okamura; Ryuji Sakagami; Jun Yamazaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012, Not refereed, Not invited - Expression and electrophysiological profile of TRPM8 in human oral squamous cell carcinoma-derived cell lines
Yoshihiko Okamoto; Ryuji Uchida; Tsuyako Ohkubo; Kazuhiko Okamura; Tetsuro Ikebe; Jun Yamazaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, Not refereed, Not invited - Salivary maxi-K channel variant expressed in diabetic db/db mice
Jun Yamazaki; Tsuyako Ohkubo; Kazuhiko Okamura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010, Not refereed, Not invited - Differences in expression of CLCA isoforms in rat salivary gland tissue may be related to the subcellular localization and function of integrins
Jun Yamazaki; Kazuhiko Okamura; Kenji Kitamura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Not refereed, Not invited - Distinct subcellular expressions of post-translationally modified Ca2+-activated Cl- channel-related molecules
Jun Yamazaki; Kazuhiko Okamura; Kenji Kitamura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007, Not refereed, Not invited - Characterization of the rat Ca2+-activated Cl- channel CLCA expressed in ductal cells of rat salivary glands
J Yamazaki; K Okamura; K Ishibashi; K Kitamura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005, Not refereed, Not invited - Ca 拮抗薬―T型，L型，N型チャネル抑制薬
北村憲司; 山﨑 純; 西島博明
心臓, 2000, Not refereed, Not invited
Books and other publications
- Clc-3 chloride channels in the pulmonary vasculature (Ed. J.X.-J. Yuan and J.P.T. Ward)
Hume, J.R; Wang, G.-X; Yamazaki, J; Ng, L.C; Duan, D, Joint work, Membrane receptors, channels and transporters in pulmonary circulation, AEME, vol.661., Hume; J.R; Wang; G.-X.; Yamazaki; J.; Ng; L.C.and Duan; D.
Humana press, 2010, Not refereed - イオンチャネル創薬―現状とその可能性、医学のあゆみ 223(6)
山崎 純, Single work, 7. Cl- チャネル創薬の現状と展望, 山崎 純
医歯薬出版, 2007, Not refereed - 一価イオンチャネル． 生体の科学 特集 53(4)
山﨑 純; 北村憲司, Single work, 脳細動脈平滑筋のクロライドチャネルと細胞間コミュニケーション, 山﨑 純、北村憲司.
医学書院, 2002, Not refereed - Ion channels in vascular smooth muscle. In Heart Physiology and Pathophysiology. (Ed. N. Sperelakis)
Joint work
Academic Press, London, U.K., 2000, Not refereed - Volume-regulated chloride channels in heart and smooth muscle. In Chloride channels. (Ed. R. Kozlowski)
Joint work
Isis Medical Media, Oxford, U.K., 1999, Not refereed
Lectures, oral presentations, etc.
- TRPM2はマウス肝マクロファージにおける炎症性サイトカインの遺伝子発現に関わる
水野 真孝; 中山 玲奈; 山口 卓哉; 山﨑 純
第6回日本獣医薬理学・毒性学科春季研究会, Mar. 2024, Not invited - サブユニット変異体によるイヌTRPV1チャネル多量体の機能変化
山﨑 純; 安藤 楓; 山口卓哉
第97回日本薬理学会年会, Dec. 2023, Not invited - イヌ、マウスおよびヒト TRPA1 におけるメントールや低温刺激に対する反応性の違い
山口卓哉; 内田邦敏; 山﨑 純
第97回日本薬理学会年会, Dec. 2023, Not invited - イヌ末梢血単核球に発現する TRPM2 の性状解析
上田 直斗; 山口 卓哉; 山﨑 純
第97回日本薬理学会年会, Dec. 2023, Not invited - 冷刺激に対するイヌ、マウスおよびヒトの TRPA1 チャネル応答性
山口卓哉; 山﨑 純
第166回日本獣医学会学術集会, Sep. 2023, Not invited - マウスクッパー細胞亜集団におけるTRPチャネル遺伝子の発現解析
中山玲奈; 山口卓哉; 山﨑 純
第5回日本獣医薬理学・毒性学科春季研究会, Mar. 2023, Not invited - イヌ末梢血単核球に発現するTRPM2の性状解析
上田直斗; 山口卓哉; 山﨑 純
第5回日本獣医薬理学・毒性学科春季研究会, Mar. 2023, Not invited - イヌTRPV1変異体が生むチャネル機能の多様性
安藤 楓; 山口卓哉; 山﨑 純
第5回日本獣医薬理学・毒性学科春季研究会, Mar. 2023, Not invited - イヌTRPM8とTRPA1のメントールに対する反応性の違い
山口卓哉; 柳川日向子; 松岡彩那; 内田邦敏; 山﨑 純
第96回日本薬理学会年会, Nov. 2022, Not invited - Role of TRPV1 in hyaluronan-induced apoptosis avoidance in MCF-7 cells
Yuki Kaguchi; Yuto Hoshino; Yui Fukuyama; Takuya Yamaguchi; Jun Yamazaki
第95回日本薬理学会年会, Mar. 2022, Not invited - Reactivity of TRPA1 to menthol differs between mouse and dog
Takuya Yamaguchi; Ayana Matsuoka; Kunitoshi Uchida; Jun Yamazaki
第95回日本薬理学会年会, Mar. 2022, Not invited - ヒアルロン酸合成酵素阻害薬によるイヌ乳腺腫瘍細胞のスフェロイド形成抑制とアポトーシス誘導
山﨑 純、伊地知秀太、吉田瑠奈、木本裕理、井上雄太、渡邊萌、山田茉里奈、齋藤光芳
第93回日本薬理学会年会, Mar. 2020, 日本薬理学会, Not invited - 救急医療での薬物療法～ショックの病態と治療～（教育講演）
山﨑 純
日本大学獣医学会, Jun. 2019, 日本大学獣医学会, Invited - 細胞のコミュニケーション―イオンと分子で伝え合う細胞社会のなりたち―
山崎 純
日本大学生物資源科学部総合研究所公開研究会（公開講座）, Dec. 2018, 日本大学生物資源科学部総合研究所, Invited - ラット皮膚再構築モデルのコラーゲンゲル収縮に対するTRPV2阻害薬による抑制効果
山﨑 純、石井太郎、内田邦敏、八田光世
第139回日本薬理学会関東部会, Oct. 2018, Not invited - アノイキス抵抗性を示すイヌ乳腺腫瘍細胞におけるヒアルロン酸の機能の解析
山田茉里奈、齋藤光芳、山﨑 純
第161回日本獣医学会学術集会, Sep. 2018, Not invited - Modification of peptidylarginine deiminase alters the stratification of rat oral mucosa
YAMAZAKI Jun
18th World Congress of Basic and Clinical Pharmacology, Jul. 2018, Not invited - 口腔粘膜上皮の構造維持に関与するペプチジルアルギニン脱イミノ化酵素
有田 晴一、八田 光世、笠 孝成、内田 邦敏、坂上 竜資、山崎 純.
第95回日本生理学会大会, Mar. 2018, Not invited - 温度感受性チャネルTRPM5の機能解析．
内田邦敏、喜多 知、笠 孝成、山﨑 純.
第59回歯科基礎医学会学術大会, Sep. 2017, Not invited - 早朝ワークショップ：最近のイオンチャネル研究から見た慢性機能異常の病態解明への展望
山﨑 純、大矢 進
第90回日本薬理学会年会, Mar. 2017, Not invited - TRPM2チャネルのインスリン分泌並びに糖尿病発症への関与
内田邦敏、山﨑 純、富永真琴.
第90回日本薬理学会年会, Mar. 2017, Invited - ラット細肺動脈平滑筋細胞における P2Y受容体刺激によるTMEM16A (anoctamin 1)チャネル活性化．
加藤健一、内田邦敏、八田光世、山﨑 純.
第90回日本薬理学会年会, Mar. 2017, Not invited - 口腔粘膜のバリア形成に寄与するペプチジルアルギニン脱イミノ化酵素．
有田晴一、笠 孝成、八田光世、内田邦敏、坂上竜資、山﨑 純.
第90回日本薬理学会年会, Mar. 2017, Not invited - 皮膚と口腔粘膜におけるフィラグリンの発現様式及び分解過程．
有田晴一、八田光世、笠 孝成、坂上竜資、山﨑 純.
第58回歯科基礎医学会学術大会, Aug. 2016, Not invited - 三次元細胞培養シートにおけるラット皮膚由来間葉細胞の分化および石灰化物形成に関わる因子．
陶山大輝、八田光世、山﨑 純.
第89回日本薬理学会年会, Mar. 2016, Not invited - クロマチン修飾酵素阻害薬の口腔がん細胞の悪性形質に対する抑制効果
八田光世、永沼香織、有田晴一、加藤健一、大久保つや子、山﨑 純.
第89回日本薬理学会年会, Mar. 2016, Not invited - 口腔がん細胞におけるエピジェネティックサイレンシングに対する3-deazaneplanocin Aの効果．
八田光世、永沼香織、山﨑 純.
第68回日本薬理学会西南部会, Nov. 2015, Not invited - 上皮細胞のイオン輸送と分化に関与したカルシウム活性化クロライドチャネル関連分子の機能発現
山﨑 純
日本薬学会第135年会, Mar. 2015, Invited
Research Themes
- がんスフェロイドのアポトーシス誘導に関与するヒアルロン酸－TRPチャネル制御系
独立行政法人日本学術振興会, 科学研究費助成事業（学術研究助成基金助成金）, Apr. 2020 - Mar. 2023
山崎 純; 岡村 和彦; 内田 邦敏 - 歯周病発症におけるTRPチャネルを介した口腔上皮バリア機能破綻の関与
独立行政法人日本学術振興会, 科学研究費助成事業（学術研究助成基金助成金）, Apr. 2018 - Mar. 2021
内田邦敏 - 上皮ケラチノサイトの上皮間葉転換を制御する分子機構
独立行政法人日本学術振興会, 科学研究費助成事業（学術研究助成基金助成金）, Apr. 2017 - Mar. 2020
Hatta Mitsutoki - 創傷治癒培養モデルを用いた口蓋裂術後瘢痕形成の制御に関する研究
日本学術振興会, 科学研究費補助金 基盤研究（C）, Apr. 2015 - Mar. 2018
石川博之 - 未分化上皮細胞選択的スプライシングによる多機能性発現の分子基盤
日本学術振興会, 科学研究費補助金 挑戦的萌芽研究, Apr. 2014 - Mar. 2018
山﨑 純 - 生体内環境を調和する硬組織再建システム
文部科学省, 私立大学戦略的研究基盤形成支援事業（分担）, Apr. 2010 - Mar. 2015
福岡歯科大学 松家茂樹 - 溶解カーボンナノチューブ高機能ナノシステムのデザイン
科学技術庁, 戦略的創造研究推進事業 (CREST), Apr. 2008 - Mar. 2014
九州大学 中嶋直敏 - 疾患の抑制におけるゲノム安定性と環境ストレスの制御
文部科学省, 私立大学学術研究高度化推進事業 学術フロンティア推進事業, Apr. 2008 - Mar. 2013
関口睦夫 - クロライドチャネル関連分子CLCAによる細胞増殖・接着の制御
学術振興会, 科学研究費補助金 基盤研究（C）, Apr. 2009 - Mar. 2012
福岡歯科大学 岡村和彦 - DNA/人工タンパク質複合体の透明フィルム化と軟組織再生用材料への応用
日本学術振興会, 科学研究費補助金 萌芽研究, Apr. 2008 - Mar. 2011
福島忠男 - Ca2+ 活性化Cl- 輸送に働くトランスポートソームの分子構成と生理機能
文部科学省, 科学研究費補助金 特定領域研究 「膜輸送複合体」（公募）, Apr. 2006 - Mar. 2008
山﨑 純 - 塩素イオン透過機能を持つ新規rCLCA分子の唾液腺における局在と生理機能の解明
日本学術振興会, 科学研究費補助金 基盤研究（C）（一般）, Apr. 2005 - Mar. 2008
山﨑 純 - The localization of calcium-activated chloride channel and its contribution on related pathologic conditions
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2006 - 2007
OKAMURA Kazuhiko; YAMAZAKI Jun - Regulation of excitability of smooth muscle by endothelium in cerebral arterioles -Intercellular humoral and electrical signal transduction-
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2001 - 2002
YAMAZAKI Jun - 心臓よりクローンしたcAMP依存性Clチャネル活性のリン酸化状態による制御機構
日本学術振興会, 科学研究費助成事業, 1999 - 2000
山崎 純 - バリウムの血管内皮細胞への流入機構と一酸化窒素生成に関する研究
日本学術振興会, 科学研究費助成事業, 1995 - 1995
山崎 純 - イヌの冠動脈における一酸化窒素合成酵素についての研究
日本学術振興会, 科学研究費助成事業, 1992 - 1992
長尾 拓; 山崎 純 - 高血圧における内皮由来弛緩物質の役割の解明
日本学術振興会, 科学研究費助成事業, 1991 - 1991
山崎 純
