Nemoto(Yamamoto) Seiko

School of Dentistry at Matsudo Department of DentistrySenior Assistant Professor

Degree

  • Mar. 2012

Research Keyword

  • sleep-disordered breathing
  • craniofacial / maxillofacial anatomy
  • アルカリホスファターゼ 低ホスファターゼ症

Field Of Study

  • Life sciences, Developmental dentistry, Orthodontics/Pediatric dentistry
  • Life sciences, Molecular biology, Molecular biology

Career

  • Apr. 2010 - Mar. 2012
    Sanford Burnham Medical Research Institute, PhD student
  • May 2007 - Mar. 2010
    日本医科大学 生化学(分子生物学・遺伝学)教室, 大学院生

Award

  • May 2025
    日本小児歯科学会, 小児歯科学雑誌 優秀論文賞
    乳歯早期脱落を呈し低ホスファターゼ症と ビタミンD 欠乏性くる病との鑑別を要した1 例
    根本(山本)晴子 小 口 恭 德 秋 鹿 ゆ い 石 川 友里香 皆 川 莉 那 小 川 京 田 嶋 華 子 清 水 武 彦
  • International Association of Pediatric Dentistry, International forum of pediatric dentistry ,Morita prize
    Gene therapy for hypophosphatasia, International society

Paper

  • Computed tomographic evaluation of the relationship between maxillary sinus morphology, mucosal thickening, and age in children
    Seiko NEMOTO-YAMAMOTO; Yurika ISHIKAWA; Yasunaru OGUCHI; Yurie OKADA; Mitsuko NAKAYAMA; Eri SAWADA-HINO; Satoshi TOKUNAGA; Chihiro IWASAKI-WATANABE; Khaliun ERDENEBULGAN; Kei OGAWA; Takashi KANEDA; Takehiko SHIMIZU
    Journal of Digital Dentistry, Jun. 2026, Refereed
    Lead
  • A Case of Early Tooth Loss Requiring Differential Diagnosis of Hypophosphatasia and Vitamin D Deficiency Rickets
    Seiko Nemoto-Yamamoto; Yasunaru Oguchi; Yui Aika; Yurika Ishikawa; Rina Minagawa; Kei Ogawa; Hanako Tajima; Takehiko Shimizu
    小児歯科学雑誌, Nov. 2024, Refereed, Not invited
    Lead
  • エナメル質形成不全症を示すエナメリン遺伝子変異マウスのエナメル質形成の解析
    清水 邦彦, 小川 京, 金尾 貴子, 牧山 早紀[加藤], 太田 雪菜, 根本 晴子[山本], 清水 武彦
    Sep. 2022
  • Influence of Masticatory Functional Loss on the Remodeling of Alveolar Bone in Rats
    Kei Ogawa; Takamichi Yamada; Norimitsu Hirai; Wataru Morita; Yurie Okada; Seiko Yamamoto-Nemoto; Takehiko Shimizu
    Open Journal of Stomatology Vol.10 No.12, Dec. 2020, Refereed, Not invited
  • Nanomaterials and Nanorobotics in Dentistry: A Review
    Yelda Kasimoglu; Derya Tabakcilar; Zeynep A. Guclu; Seiko Yamamoto-Nemoto; Elif B. Tuna; Bugra Ozen; Tamer Tuzuner; and Gökhan Ince
    Journal of Dentistry Indonesia, Aug. 2020, Refereed, Not invited
  • 横紋筋肉腫の治療後に認められた顎骨の発育不全および歯の形成障害の1例
    眞田 奈緒美; 嶋田 理菜; 岡田 裕莉恵; 山口 茜; 木村 奈緒; 根本 晴子; 本; 清水 邦彦; 清水 武彦
    小児歯科学雑誌, Nov. 2018
  • Oral Symptoms and Bone Observations in Odonto-Hypophosphatasia
    Seiko Yamamoto-Nemoto; Rina Shimada; Hanako Tajima; Emiko Iwasawa; Yoko Shimizu; Elif Bahar Tuna; Kei Ogawa; Atsushi Watanabe; Takehiko Shimizu
    Open Journal of Stomatology, Dec. 2016, Refereed, Not invited
    Lead
  • In vivo neurochemical evidence that delta1-, delta2-and mu2-opioid receptors, but not mul1opioid receptors, inhibit acetylcholine efflux in the nucleus accumbens of freely moving rats
    Yuri Kiguchi; Yuri Aono; Yuriko Watanabe; Seiko Yamamoto-Nemoto; Kunihiko Shimizu; Takehiko Shimizu; Yasuhiro Kosuge; John L. Waddington; Kumiko Ishige; Yoshihisa Ito; Tadashi Saigusa
    EUROPEAN JOURNAL OF PHARMACOLOGY, Oct. 2016, Refereed, Not invited
  • What is the Best Root Surface Treatment for Avulsed Teeth?
    Elif B. Tuna; Duygu Yaman; Seiko Yamamato
    The Open Dentistry Journal, Sep. 2014, Refereed, Not invited
  • Study on factors that affect caries susceptibility in mice
    Chika Endo; Seiko Yamamoto; Kunihiko Shimizu
    Pediatric Dental Journal, 2014, Not refereed, Not invited
  • Rescue of Severe Infantile Hypophosphatasia Mice by AAV-Mediated Sustained Expression of Soluble Alkaline Phosphatase
    Tae Matsumoto; Koichi Miyake; Seiko Yamamoto; Hideo Orimo; Noriko Miyake; Yuko Odagaki; Kumi Adachi; Osamu Iijima; Sonoko Narisawa; Jose Luis Millan; Yoshitaka Fukunaga; Takashi Shimada
    Human gene therapy, Nov. 2011, Refereed, Not invited
  • Prolonged Survival and Phenotypic Correction of Akp2(-/-) Hypophosphatasia Mice by Lentiviral Gene Therapy
    Seiko Yamamoto; Hideo Orimo; Tae Matsumoto; Osamu Iijima; Sonoko Narisawa; Takahide Maeda; Jose Luis Millan; Takashi Shimada
    JOURNAL OF BONE AND MINERAL RESEARCH, Jan. 2011, Refereed, Not invited

MISC

  • 混合歯列期に認められた多数乳臼歯にわたる内部吸収の1例
    根本(山本)晴子 他
    日大口腔科学, 2019, Refereed, Not invited
  • Histomorphometrical Analysis in Murine Hypophosphatasia.
    Seiko Yamamoto-Nemoto; Eri Yokoi; Kei Ogawa; Chika Endo; Nao Ogawa; Kunihiko Shimizu; Takehiko Shimizu
    JOURNAL OF BONE AND MINERAL RESEARCH, Dec. 2017, Not refereed, Not invited
  • A case of dental treatment because a support of the social involvement in socially withdrawn child.
    根本(山本) 晴子; 澤本 圭南子; 横井 絵理; 嶋田 理菜; 山口 茜; 岩澤 依充子; 荒井 清司; 清水 武彦
    日大口腔科学, 2017, Refereed, Not invited
    Lead
  • Improvement of bone and dental phenotype of murine hypophosphatasia mediated by a singe injection of lentiviral gene therapy
    Open Journal of Stomatology, 2017, Refereed, Not invited
    Lead
  • 3-D image analysis on palate growth changes from birth to 1 month in healthy infants
    Fusae Ishida; Masanori Mashiko; Ikuko Shimabukuro; Seiko Yamamoto; Kunihiko Shimizu; Takahide Maeda
    Pediatric Dental Journal, Apr. 2013, Refereed, Not invited

Books and other publications

  • Japanese Journal of Clinical Dentistry For Children
    Contributor, 低ホスファターゼ症の基礎研究と歯科的臨床像
    東京臨床出版株式会社, Feb. 2018, Not refereed

Lectures, oral presentations, etc.

  • 下顎乳前歯へのストロー様異物の陥入を認めた 1 例
    上野純子,根本(山本)晴子,清水邦彦,清水武彦
    日本小児歯科学会第39会関東地方会大会, Oct. 2024
  • エナメリン遺伝子変異マウスにおけるエナメル質形成不全症の組織学的検討
    小川京; 森田 渉; 澤本圭南子; 根本(山本)晴子; 清水邦彦; 清水 武彦
    第62回日本小児歯科学会大会, May 2024
  • 小児の上顎洞炎のパターン分類の検討
    根本(山本)晴子; 岩澤依充子; 笠井桃江; 上野純子; 小川京; 清水武彦
    第62回日本小児歯科学会大会, May 2024
  • The nasal cavity in a boy with rhinitis was enlarged using RAMPA therapy: an anterosuperior maxillary protraction appliance
    Seiko Nemoto-Yamamoto, Yuko Okai-Kojima, Mitsuko Nakayama, Yasushi Mitani, Takehiko Shimizu
    19th symposium of international Association of Facial Growth Guidance, Apr. 2024
  • RAMPAセラピーによる鼻腔の容積変化
    岡井; 小嶋; 有子; 根本; 山; 晴子; 仲田 拡人; 三谷 寧
    第18回 日本小児耳鼻咽喉科学会総会・学術講演会,, Nov. 2023
  • 当科の研究から30年後の小児歯科を予測する
    牧山(加藤)早紀; 岩﨑(渡邉)千尋; 伊藤龍朗; 根本(山本)晴子; 小川京; 清水邦彦; 清水武彦
    日本小児歯科学会第38会関東地方会大会, Oct. 2023
  • Histomorphometrical analysis in coltical bone of murine hypophosphatasia
    Seiko Yamamoto-Nemoto; Yasuchika Ogawa; Mari Tanaka; Eri Yokoi; Hironori Tanaka; Nao Ogawa; Kei Ogawa; Takehiko Shimizu
    第58回日本小児歯科学会大会, May 2021
  • 横紋筋肉腫の治療により生じた歯の形成障害の1例
    眞田 奈緒美; 宮良 美都子; 嶋田 理菜; 根本 晴子; 本; 清水 邦彦; 清水 武彦; 諸星 弘世
    第57回日本小児歯科学会大会, May 2019
  • Histomorphometrical Analysis in Murine Hypophosphatasia.
    Consortium of Biological Sciences 2017, Dec. 2017, Not invited
  • Histomorphometrical Analysis in Murine Hypophosphatasia.
    American Society for Bone and Mineral Research 2017 Annual Meeting, Sep. 2017, Not invited
  • 低ホスファターゼ症モデルマウスのエナメル質の研究
    根本(山本) 晴子、横井 絵理、小川 京、清水 邦彦、清水 武彦
    日本分子生物学会 第39回日本分子生物学会年会, Dec. 2016, Not invited
  • Improvement of enamel and skeletal defects in murine hypophosphatasia via lentiviral gene therapy
    American Society for Bone and Mineral Research 2014 Annual Meeting, Sep. 2014, Not invited
  • Comparison of the different caries susceptibility in mice
    Chika Endo
    10th IADR World Congress on Preventive Dentistry, Oct. 2013, Not invited
  • Therapeutic effect of hard tissue by lentivairal gene therapy for hypophosphatasia
    24th international association of pediatric dentistry Seoul congress, Jun. 2013, International association of pediatric dentistry, Not invited
  • Therapeutic effect of hard tissue by gene therapy for hypophosphatasia
    第51回日本小児歯科学会大会, May 2013, Not invited
  • Improvement of enamel defect mediated lentivairal gene therapy for hypophosphatasia
    91st General Session & Exhibition of the IADR, Mar. 2013, International association of dentistry, Not invited
  • Effects of mastication on the spatial memory in mice hippocampus
    91st General Session & Exhibition of the IADR, Mar. 2013, Not invited
  • 低ホスファターゼ症の遺伝子治療
    日本小児歯科学会 第27回関東地方大会・総会『若き研究者の集い』, Oct. 2012, Not invited
  • 低ホスファターゼ症のモデルマウスを用いた遺伝子治療
    第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会(BMB2010), Dec. 2010, Not invited
  • AAV Vector Mediated Enzyme Replacement Therapy of Hypophosphatasia (HPP) Model Mice
    American Society of Gene & Cell Therapy 13th Annual Meeting, May 2010, Not invited
  • Adeno-associated virus (AAV) type8 mediated systemic neonatal gene therapy for hypophosphatasia.
    The American Society of Human Genetics 59th Annual Meeting, Oct. 2009, Not invited
  • Lentivirus mediated neonatal gene therapy for severe infantile hypophoshatasia
    11th International Congress of Inborn Errors of Metabolism, Sep. 2009, Not invited
  • Long Term Phenotypic Correction of Severe Infantile Hypophosphatasia in a Mouse Model by Neonatal Injection of Lentiviral Vector
    American Society of Gene Therapy 12th Annual Meeting, May 2009, Not invited
  • 低ホスファターゼ症のレンチウイルスベクターを用いた遺伝子治療
    日本人類遺伝学会第53回大会, Sep. 2008, Not invited

Research Themes

  • Analysis of dental pulp stem cells derived from hypophosphatasia model mice.