NAKANISHI Yusuke

College of Bioresource Sciences Department of Zoological ScienceAssistant Professor

Researcher Information

Research Keyword

  • 癌免疫 粘膜免疫

Field Of Study

  • Life sciences, Immunology, Immunology

Career

  • Jun. 2014 - Mar. 2017
    東京医科歯科大学, 難治疾患研究所 IBD難病基盤応用研究プロジェクト室, 助教
  • Jan. 2010 - May 2014
    東京医科歯科大学, 難治疾患研究所 生体防御学分野, 特任講師
  • Apr. 2006 - Dec. 2009
    Yale University, 医学部 免疫部門, 博士研究員

Educational Background

  • 2006
    日本大学, 生物資源科学研究科, 生物資源利用科学専攻
Research activity information

Paper

  • ★Pannexin1 channel-dependent secretome from apoptotic tumor cells shapes immune-escape microenvironment
    Hiroki Mukai; Nagisa Miki; Hikari Yamada; Haruka Goto; Taiko Kawakami; Akari Suzuki; Kazuhiko Yamamoto; Yusuke Nakanishi; Kyoko Takahashi
    Biochem Biophys Res Commun., Aug. 2022, Refereed, Not invited
    Corresponding
  • Gut microbiota-dependent adaptor molecule recruits DNA methyltransferase to the TLR4 gene in colonic epithelial cells to suppress inflammatory reactions
    Hikari Narabayashi; Chiharu Koma; Kazuaki Nakata; Mion Ikegami; Yusuke Nakanishi; Jun Ogihara; Masato Tsuda; Akira Hosono; Shigemasa Hanazawa; Kyoko Takahashi.
    Front Mol Biosci., Oct. 2022, Refereed, Not invited
  • Post-translational suppression of the high affinity IgE receptor expression on mast cells by an intestinal bacterium
    S. Fukatsu; H. Horinouchi; S. Nagata; R. Kamei; D. Tanaka; W. Hong; Y. Kazami; M; Fujimori; K. Itoh; Y. Momose; K. Kasakura; A. Hosono; S. Kaminogawa; S. Hanazawa; Y. Nakanishi; K.Takahashi
    Immunobiology, Mar. 2021, Refereed, Not invited
  • IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
    Kana Minamide; Taku Sato; Yusuke Nakanishi; Hiroshi Ohno; Tamotsu Kato; Jumpei Asano; Toshiaki Ohteki
    Sci Rep, Sep. 2020, Refereed, Not invited
  • Regulation of Gene Expression Through Gut Microbiota-Dependent DNA Methylation in Colonic Epithelial Cells
    Kyoko Takahashi; Yutaka Sugi; Kou Nakano; Tetsuro Kobayakawa; Yusuke Nakanishi; Masato Tsuda; Akira Hosono; Shuichi Kaminogawa
    Immunohorizons ., Apr. 2020, Refereed, Not invited
  • Role of eosinophils in a murine model of inflammatory bowel disease.
    Wang Z; Adachi S; Kong L; Watanabe D; Nakanishi Y; Ohteki T; Hoshi N; Kodama Y.
    Biochem Biophys Res Commun., 2019, Refereed, Not invited
  • IFN-γ-dependent epigenetic regulation instructs colitogenic monocyte/macrophage lineage differentiation in vivo.
    Nakanishi Y; Sato T; Takahashi K; Ohteki T.
    Mucosal Immunology, 2018, Refereed, Not invited
    Lead
  • Commensal microbiota-induced microRNA modulates intestinal epitelilal permeability through the small GTPase ARF4.
    K.Nakata; Y.Sugi; T.KObayakawa; Y.Nakanishi; M.Tsuda; A.Hosono; S.Kaminogawa; S.Hanazawa; K.Takahashi.
    Journal of Biological Chemistry, 2017, Refereed, Not invited
  • Commensal gram-positive bacteria initiates colitis by inducing monocyte/macrophage mobilization.
    Nakanishi Y; Sato T; Ohteki T.
    Mucosal Immunology., 2015, Not refereed, Not invited
    Lead
  • Orally administered Bifidobacterium triggers immune responses following capture by CD11c(+) cells in Peyer's patches and cecal patches.
    Hiramatsu Y; Hosono A; Konno T; Nakanishi Y; Muto M; Suyama A; Hachimura S; Sato R; Takahashi K; Kaminogawa S.
    Cytotechnology., 2011, Refereed, Not invited
  • CD8+ T lymphocyte mobilization to virus-infected tissue requires CD4+ T-cell help.
    Nakanishi Y; Lu B; Gerard C; Iwasaki A.
    Nature, 2009, Refereed, Not invited
    Lead
  • Increase in terminal restriction fragments of Bacteroides-derived 16S rRNA genes after administration of short-chain fructoologosaccharides.
    Nakanishi Y; Murashima K; Ohara H; Suzuki T; Hayashi H; Sakamoto M; Fukasawa T; Kubota H; Hosono H; Kono T; Kaminogawa S; Benno Y.
    Applied and Environmental Microbiology., 2006, Refereed, Not invited
    Lead
  • Characteristic immune response in Peyer’s patch cells induced by oral administration of Bifidobacterium componets.
    Nakanishi; A Hosono; Y Hiramatu; T Kimura; R Nakamura; S Kaminogawa.
    Cytotechnology., 2005, Not refereed, Not invited
  • Dietary fructoologosaccharide induce immunoregulation of intestinal IgA secretion by murine Peyer’s patch cells.
    A Hosono; A Ozawa; R Kato; Y Ohnishi; Y Nakanishi; T Kimura; R Nakamura.
    Bioscience,Biotechnology, and Biochemistry, 2003, Refereed, Not invited

Research Themes

  • がん細胞の細胞死が腫瘍微小環境の構築に与える影響の解明
    日本学術振興会, 科学研究費助成事業, 01 Apr. 2022 - 31 Mar. 2025
    中西 祐輔
  • メタボリックレギュレーターとしてのマスト細胞の新規な役割とその制御
    日本学術振興会, 科学研究費助成事業, 01 Apr. 2020 - 31 Mar. 2023
    高橋 恭子; 中西 祐輔; 細野 朗
  • Analyze the antitumor activity of neutrophils extracellular traps
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2019 - 31 Mar. 2022
    NAKANISHI Yusuke
  • Identify the commensal bacteria that development of colitis
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2014 - 31 Mar. 2016
    Nakanishi Yusuke
  • The role of eosinophil in the gut homeostasis
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 2011 - 2012
    NAKANISHI Yusuke
  • 腸管免疫系を調節する食品由来成分の構造と機能特性
    日本学術振興会, 科学研究費助成事業, 2005 - 2006
    中西 祐輔