Yamagata Kazuo

College of Bioresource SciencesProject Professor

Research Keyword

  • ポリフェノール
  • アストロサイト
  • フィトケミカル
  • 動脈硬化
  • タイトジャンクション
  • 遺伝子制御
  • 細胞応答
  • 病因解析
  • 血液脳関門
  • 血管内皮細胞
  • SHRSP
  • 脳卒中

Field Of Study

  • Life sciences, Pathobiochemistry, Pathological physiology
  • Life sciences, Cell biology, Cell Biology
  • Life sciences, Food sciences, Molecular Neutrition
  • Life sciences, Food sciences, Food Science

Educational Background

  • 1978
    Nihon University, Graduate School, Division of Agriculture, 食品工学専攻

Paper

  • Onion quercetin inhibits vascular endothelial cell dysfunction and prevents hypertension.
    Yamagata K.
    European Food Research and Technology, Oct. 2023, Refereed
    Lead
  • Docosahexaenoic acid inhibits ischemic stroke to reduce vascular dementia and Alzheimer’s disease.
    Yamagata K.
    Prostaglandins and Other Lipid Mediators., Oct. 2023, Refereed
    Lead
  • Fatty acids act on vascular endothelial cells and influence the development of cardiovascular disease
    Yamagata K.
    Prostaglandins & Other Lipid Mediators, Apr. 2023, Refereed
    Lead
  • 脳卒中ラットで示された食品成分の有用な作用
    山形一雄
    SHR News Letter, Jan. 2022, Refereed
    Lead
  • Lactate supply from astrocytes to neurons and its role in ischemic stroke-induced neurodegeneration.
    Yamagata K.
    Neuroscience, Jan. 2022, Refereed
    Lead
  • Defective Function of the Blood–Brain Barrier in a Stroke-Prone Spontaneously Hypertensive Rat: Evaluation in an In Vitro Cell Culture Model
    Shinsuke Nakagawa; Hiroki Ohara; Masami Niwa; Kazuo Yamagata; Toru Nabika
    Cellular and Molecular Neurobiology, Jan. 2022, Refereed, Not invited
  • Potential effects of soy isoflavones on the prevention of metabolic syndrome
    Yamagata K; Yamori Y.
    Molecules, Sep. 2021, Refereed
    Lead
  • Altered properties of neurons and astrocytes and the effects of food components in stroke-prone spontaneously hypertensive rats.
    Yamagata K; Yamori Y.
    Journal of Cardiovascular Pharmacology, Jun. 2021, Refereed, Not invited
    Lead
  • Oleic acid and oleoylethanolamide decrease interferon-γ-induced expression of PD-L1 and induce apoptosis in human lung carcinoma cells.
    Yamagata K; Uzu E; Yoshigai Y; Kato C; Tagami M.
    European Journal of Pharmacology, Jun. 2021, Refereed, Not invited
    Lead
  • Astrocyte-induced synapse formation and ischemic stroke.
    Yamagata K.
    Journal of Neuroscience Research, May 2021, Refereed, Not invited
    Lead
  • Prevention of cardiovascular disease through modulation of endothelial cell function by dietary seaweed intake.
    Yamagata K.
    Phytomedicine Plus, Apr. 2021, Refereed, Not invited
    Lead
  • 野菜や果物に含まれるフラボノイドの高血圧に対する有用な作用.
    山形一雄
    湘南健康長寿研究会会誌, Mar. 2021, Not refereed, Invited
    Lead
  • Dietary docosahexaenoic acid inhibits neurodegeneration and prevents stroke.
    Yamagata K.
    Journal of Neuroscience Research, Feb. 2021, Refereed, Not invited
    Lead
  • [Invited review article] Prevention of endothelial dysfunction and cardiovascular benefits by n-3 fatty acids-inhibiting action on oxidative stress and inflammation.
    Yamagata K.
    Current Pharmaceutical Design, Sep. 2020, Refereed, Invited
    Lead
  • Astrocytic nutritional dysfunction associated with hypoxia-induced neuronal vulnerability in stroke-prone spontaneously hypertensive rats.
    Yamagata K.
    Neurochemistry International, Jul. 2020, Refereed, Not invited
    Lead
  • [翻訳] 食事性脂肪酸による内皮細胞応答と血管機能の調節 (Youjia, Modulation of endothelial cell responses and vascular function by dietary fatty acids. Nut Res Vol.77(9):614–629)
    山形 一雄
    栄養学レビュー, May 2020, Refereed, Invited
    Lead
  • Protective effect of epigallocatechin gallate on endothelial disorders in atherosclerosis.
    Yamagata Kazuo
    Journal of Cardiovascular Pharmacology., May 2020, Refereed, Not invited
    Lead
  • Dietary apigenin reduces induction of LOX-1 and NLRP3 expression, leukocyte adhesion and acetylated low-density lipoprotein uptake in human endothelial cells exposed to trimethylamine-N-oxide. (In issue commentary page 513-515)
    Yamagata; K; Hashiguchi K; YamamotoH; Tagami M.
    Journal of Cardiovascular Pharmacology., Dec. 2019, Refereed, Not invited
    Lead
  • Inhibition of endothelial dysfunction by dietary flavonoids and preventive effects on cardiovascular disease.
    Yamagata K; Yamori Y
    Journal of Cardiovascular Pharmacology., Dec. 2019, Refereed, Not invited
    Lead
  • 脳卒中ラット由来アストロサイトの神経細胞へのエネルギー供給能.
    Yamagata K
    SHR News Letter, Dec. 2019, Not refereed, Invited
    Lead
  • [Invited review article] Polyphenols regulate endothelial functions and reduce the risk of cardiovascular disease.
    Yamagata Kazuo
    Current Pharmaceutical Design., Nov. 2019, Refereed, Not invited
    Lead
  • Soy isoflavones inhibit endothelial cell dysfunction and prevent cardiovascular disease.
    Yamagata Kazuo
    Journal of Cardiovascular Pharmacology, Sep. 2019, Refereed, Not invited
    Lead
  • 血管内皮細胞の機能不全と大豆イソフラボンの動脈硬化予防
    山形 一雄
    New Food Industry, May 2019, Refereed, Not invited
    Lead
  • 食品と健康長寿 -長寿食の理にかなったしくみ-
    山形 一雄
    湘南健康長寿研究会会誌, Mar. 2019, Not refereed, Not invited
    Lead
  • Chlorogenic acid regulates apoptosis and stem cell marker-related gene expression in A549 human lung cancer cells
    Kazuo Yamagata; Yuri Izawa; Daiki Onodera; Motoki Tagami
    Molecular and Cellular Biochemistry, Apr. 2018, Refereed, Not invited
    Lead
  • Do coffee polyphenols have a preventive action on metabolic syndrome associated endothelial dysfunctions? An assessment of the current evidence
    Kazuo Yamagata
    Antioxidants, Feb. 2018, Refereed, Not invited
    Lead
  • ライフサイエンスを基盤にした食品機能に関する授業展開-講義 「分子栄養学」での取り組み-
    山形 一雄
    日本大学生物資源科学部教職課程紀要, Sep. 2017, Not refereed, Not invited
    Lead
  • Arginine vasopressin altered the expression of monocarboxylate transporters in cultured astrocytes isolated from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats
    Kazuo Yamagata; Natsumi Takahashi; Nozomi Akita; Toru Nabika
    JOURNAL OF NEUROINFLAMMATION, Sep. 2017, Refereed, Not invited
    Lead
  • A phytoestrogen supplement prevents the altered gene expression associated with pregnancy implantation induced by IL-1β in endometrial epithelial cells.
    Suzuki Sayaka*; Nakashima Noe; Kageyama Masakatsu; Yamagata Kazuo** (SS* and KY** contributed equally)
    Reproductive Biology, Aug. 2017, Refereed, Not invited
    Lead
  • Docosahexaenoic acid regulates vascular endothelial cell function and prevents cardiovascular disease
    Kazuo Yamagata
    LIPIDS IN HEALTH AND DISEASE, Jun. 2017, Refereed, Not invited
    Lead
  • Lutein Regulates the Expression of Apoptosis-related Genes and Stem Cell Markers in A549 Human Lung Cancer Cells
    Kazuo Yamagata; Ayame Fujiwara; Daiki Onodera; Tagami Motoki
    NATURAL PRODUCT COMMUNICATIONS, Jun. 2017, Refereed, Not invited
    Lead
  • Different effects of arginine vasopressin on high-mobility group box 1 expression in astrocytes isolated from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats.
    Yamagata K; Sone N; Suguyama S; Nabika T.
    International Journal of Experimental Pathology (IJEP), Mar. 2016, Refereed, Not invited
    Lead
  • Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence
    Kazuo Yamagata; Sayaka Suzuki; Motoki Tagami
    PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, Jan. 2016, Refereed, Not invited
    Lead
  • α-マンゴスチンの健康効果
    秋田 佳小里、山形 一雄
    New Food Industry, Jan. 2016, Not refereed, Not invited
    Corresponding
  • Epigallocatechin-3-gallate inhibits VCAM-1 expression and apoptosis induction associated with LC3 expressions in TNF alpha-stimulated human endothelial cells
    Kazuo Yamagata; Yajie Xie; Sayaka Suzuki; Motoki Tagami
    PHYTOMEDICINE, Apr. 2015, Refereed, Not invited
    Lead
  • Dietary polyphenols regulate endothelial function and prevent cardiovascular disease
    Kazuo Yamagata; Motoki Tagami; Yukio Yamori
    Nutrition, 2015, Refereed, Not invited
    Lead
  • ARGININE VASOPRESSIN REGULATED ASCT1 EXPRESSION IN ASTROCYTES FROM STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS AND CONGENIC SHRPCH1_18 RATS
    K. Yamagata; M. Yamamoto; K. Kawakami; H. Ohara; T. Nabika
    NEUROSCIENCE, May 2014, Refereed, Not invited
    Lead
  • Docosahexaenoic acid decreases TNF-alpha-induced lectin-like oxidized low-density lipoprotein receptor-1 expression in THP-1 cells
    Kazuo Yamagata; Chiaki Tusruta; Akane Ohtuski; Motoki Tagami
    PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, Apr. 2014, Refereed, Not invited
    Lead
  • Epigallocatechin 3-gallate inhibits 7-ketocholesterol-induced monocyte-endothelial cell adhesion
    Kazuo Yamagata; Noriko Tanaka; Koichi Suzuki
    MICROVASCULAR RESEARCH, Jul. 2013, Refereed, Not invited
    Lead
  • 血管内皮細胞の健全性に対するポリフェノールの作用特性
    山形一雄、田上幹樹
    New Food Industry, Jun. 2013, Not refereed, Not invited
    Lead
  • 抗酸化栄養素の虚血性脳卒中に対する予防効果
    山形一雄
    New Food Industry, Apr. 2013, Not refereed, Not invited
    Lead
  • Dietary beta-carotene regulates interleukin-1 beta-induced expression of apolipoprotein E in astrocytes isolated from stroke-prone spontaneously hypertensive rats
    Kazuo Yamagata; Chika Nakayama; Koichi Suzuki
    NEUROCHEMISTRY INTERNATIONAL, Jan. 2013, Refereed, Not invited
    Lead
  • Dietary apigenin regulates high glucose and hypoxic reoxygenation-induced reductions in apelin expression in human endothelial cells
    Kazuo Yamagata; Chika Tagawa; Hiroshi Matsufuji; Makoto Chino
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Aug. 2012, Refereed, Not invited
    Lead
  • β-carotene reverses the IL-1β-mediated reduction in paraoxonase-1 expression via induction of the CaMKKII pathway in human endothelial cells
    Yamagata K; Tanaka N; Matsufuji H; Chino M
    Microvas Res, Jun. 2012, Refereed, Not invited
    Lead
  • Effect of tocopherol on the ischemia-reperfusion injury of the brain
    Kazuo Yamagata; Yukio Yamori
    Tocopherol: Sources, Uses and Health Benefits, 2012
  • Pathological alterations of astrocytes in stroke-prone spontaneously hypertensive rats under ischemic conditions
    Kazuo Yamagata
    NEUROCHEMISTRY INTERNATIONAL, Jan. 2012, Refereed, Not invited
    Lead
  • Apigenin inhibits tumor necrosis factor alpha plus high glucose-induced LOX-1 expression in human endothelial cells
    Kazuo Yamagata; Akinori Miyashita; Makoto Chino; Hiroshi Matsufuji
    MICROVASCULAR RESEARCH, Jan. 2011, Refereed, Not invited
    Lead
  • ゴマ若葉に含まれるポリフェノール成分のラジカル消去
    松藤寛、大森潤一、後藤修一、千野誠、和田悦治、内田あゆみ、深堀勝謙、山形一雄、櫻井英敏
    日本食品科学工学会誌, Jan. 2011, Refereed, Not invited
  • 天然酸化防止剤ローズマリー抽出物中の活性成分と活性寄与率
    松藤寛、千野誠、山形一雄、山崎壮
    日本食品化学学会誌, 2011, Refereed, Not invited
  • NEURONAL VULNERABILITY OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS TO ISCHEMIA AND ITS PREVENTION WITH ANTIOXIDANTS SUCH AS VITAMIN E
    K. Yamagata; M. Tagami; Y. Yamori
    NEUROSCIENCE, Sep. 2010, Refereed, Not invited
    Lead
  • SDS-PAGEによる既存添加物酵素のタンパク質分離パターン
    秋山卓美、佐々木亮、山崎壮、棚元憲一、山形一雄、河村葉子
    日本食品化学学会誌, Jul. 2010, Refereed, Not invited
  • Dietary flavonoid apigenin inhibits high glucose and tumor necrosis factor alpha-Induced adhesion molecule expression in human endothelial cells
    Kazuo Yamagata; Akinori Miyashita; Hiroshi Matsufuji; Makoto Chino
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Feb. 2010, Refereed, Not invited
    Lead
  • Stroke status evoked adhesion molecule genetic alterations in astrocytes isolated from stroke-prone spontaneously hypertensive rats and the apigenin inhibition of their expression
    Kazuo Yamagata; Takuya Kitazawa; Masahiro Shinoda; Chika Tagawa; Makoto Chino; Hiroshi Matsufuji
    Stroke Research and Treatment, 2010, Refereed, Not invited
    Lead
  • Effects of Nonthermal Processes on the Inactivation of Microorganisms and Antioxidants in Minimally Processed Vegetables
    Hiroshi Matsufuji; Soichi Furukawa; Kiyotaka Teranishi; Kazumichi Kawaharada; Makoto Chino; Kazuo Yamagata; Hirokazu Ogihara; Makari Yamasaki
    FOOD SCIENCE AND TECHNOLOGY RESEARCH, Mar. 2009, Refereed, Not invited
  • Vitamin E regulates SMase activity, GSH levels, and inhibits neuronal death in stroke-prone spontaneously hypertensive rats during hypoxia and reoxygenation.
    Yamagata K; Ichinose S; Tagawa C; Tagami M.
    J Exp Stroke & Translational Medicine, Feb. 2009, Refereed, Not invited
    Lead
  • Protective effects of ebselen, a seleno-organic antioxidant on neurodegeneration induced by hypoxia and reperfusion in stroke-prone spontaneously hypertensive rat
    K. Yamagata; S. Ichinose; A. Miyashita; M. Tagami
    NEUROSCIENCE, May 2008, Refereed, Not invited
    Lead
  • Nitric oxide reduces astrocytic lactate production and induces neuronal vulnerability in stroke-prone spontaneously hypertensive rats.
    Yamagata K; Tagami M; Yamori Y
    Glia, Apr. 2008, Refereed, Not invited
    Lead
  • 抗酸化物質の2成分混合系におけるDPPHラジカル消去活性
    松藤 寛、佐々怜 一郎、本間友輝、宮島拓臣、千野 誠、山崎 壮、島村智子、受田浩之、松井利郎、松本清、山形一雄.
    日本食品科学工学会誌, 2008, Refereed, Not invited
  • Adenosine induces expression of glial cell line-derived neurotrophic factor (GDNF) in primary rat astrocytes
    Kazuo Yamagata; Kumiko Hakata; Aya Maeda; Chiemi Mochizuki; Hiroshi Matsufuji; Makoto Chino; Yukio Yamori
    NEUROSCIENCE RESEARCH, Dec. 2007, Refereed, Not invited
    Lead
  • Detection of recombinant DNA of genetically modified (GM) soybeans in heat-treated GM soybeans and commercial natto
    Yoshiteru Kakihara; Hiroshi Matsufuji; Makoto Chino; Kazuo Yamagata
    FOOD CONTROL, Oct. 2007, Refereed, Not invited
  • Potassium bromate treatment predominantly causes large deletions, but not GC > TA transversion in human cells
    Yang Luan; Takayoshi Suzuki; Rajaguru Palanisamy; Yoshio Takashima; Hiroko Sakamoto; Mayumi Sakuraba; Tomoko Koizumi; Mika Saito; Hiroshi Matsufuji; Kazuo Yamagatae; Teruhide Yamaguchi; Makoto Hayashi; Masamitsu Honma
    MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, Jun. 2007, Refereed, Not invited
  • Stability to light, heat, and hydrogen peroxide at different pH values and DPPH radical scavenging activity of acylated anthocyanins from red radish extract
    Hiroshi Matsufuji; Hirotsugu Kido; Hisashi Misawa; Junichi Yaguchi; Takashi Otsuki; Makoto Chino; Mitsuharu Takeda; Kazuo Yamagata
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, May 2007, Refereed, Not invited
  • 食の安全・安心と健康障害を考える
    桜門春秋, Apr. 2007, Not refereed, Not invited
    Lead
  • 既存添加物エステル系ガムベースの成分分析
    多田敦子、増田愛乃、杉本直樹、山形一雄、棚元憲一
    食品衛生学雑誌, 2007, Refereed, Not invited
  • Glutamate reduces secretion of L-serine in astkocytes isolated from stroke-prone spontaneously hypertensive rats
    K. Yamagata; Y. Shoji; T. Terashima; H. Yokogoshi
    NEUROSCIENCE, Dec. 2006, Refereed, Not invited
    Lead
  • Genotoxicity of acrylamide and glycidamide in human lymphoblastoid TK6 cells.
    Naoki Koyama; Hiroko Sakamoto; Mayumi Sakuraba; Tomoko Koizumi; Yoshio Takashima; Makoto Hayashi; Hiroshi Matsufuji; Kazuo Yamagata; Shuichi Masuda; Naohide Kinae; Masamitsu Honma
    Mutation research, Feb. 2006
  • Genotoxicity of acrylamide and glycidamide in human lymphoblastoid TK6 cells
    N Koyama; H Sakamoto; M Sakuraba; T Koizumi; Y Takashima; M Hayashi; H Matsufuji; K Yamagata; S Masuda; N Kinae; M Honma
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Feb. 2006, Refereed, Not invited
  • 既存添加物ウルシロウの成分分析
    金哲龍、多田敦子、松本直樹、佐藤恭子、増田愛乃、山形一雄、棚元憲一
    食品衛生学雑誌, 2006, Refereed, Not invited
  • Detailed examination of cartilage formation and endochondral ossification using human mesenchymal stem cells
    S Ichinose; K Yamagata; Sekiya, I; T Muneta; M Tagami
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Jul. 2005, Refereed, Not invited
  • 脳卒中ラット(SHRSP/Izm)を用いた神経細胞障害の予防に関する研究
    SHR News Letter, 2005, Not refereed, Not invited
    Lead
  • Hypoxia-induced changes in tight junction permeability of brain capillary endothelial cells are associated with IL-1beta and nitric oxide
    K Yamagata; M Tagami; F Takenaga; Y Yamori; S Itoh
    NEUROBIOLOGY OF DISEASE, Dec. 2004, Refereed, Not invited
    Lead
  • Mycoleptodonoides aitchisonii affects brain nerve growth factor concentration in newborn rats
    S Okuyama; NV Lam; T Hatakeyama; T Terashima; K Yamagata; H Yokogoshi
    NUTRITIONAL NEUROSCIENCE, Oct. 2004, Refereed, Not invited
  • Amlodipine and carvedilol prevent cytotoxicity in cortical neurons isolated from stroke-prone spontaneously hypertensive rats
    K Yamagata; S Ichinose; M Tagami
    HYPERTENSION RESEARCH, Apr. 2004, Refereed, Not invited
    Lead
  • Ca2+ oscillations regulated by Na+-Ca2+ exchanger and plasma membrane Ca2+ pump induce fluctuations of membrane currents and potentials in human mesenchymal stem cells
    S Kawano; K Otsu; S Shoji; K Yamagata; M Hiraoka
    CELL CALCIUM, Aug. 2003, Refereed, Not invited
  • Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes
    K Yamagata; M Tagami; Y Torii; F Takenaga; S Tsumagari; S Itoh; Y Yamori; Y Nara
    GLIA, Jan. 2003, Refereed, Not invited
    Lead
  • Polyunsaturated fatty acids induce tight junctions to form in brain capillary endothelial cells
    K Yamagata; M Tagami; F Takenaga; Y Yamori; Y Nara; S Itoh
    NEUROSCIENCE, 2003, Refereed, Not invited
    Lead
  • Genetic and fine structural study of the differentiation between human mesenchimal stem cell to adipocyte.
    Tagami M; Ichinose S; Yamagata K; Shoji S; Hiroaki M; Fujino H; Kawano S.
    Cell Tissue Res, 2003, Refereed, Not invited
  • 機能性食品におけるEBMの必要性・重要性.
    山形一雄、横越英彦.
    機能性食品と薬理栄養, 2003, Not refereed, Not invited
    Lead
  • SHRSPアストロサイトにおけるGDNFの発現変異
    山形一雄、田上幹樹、池田克巳、奈良安雄、家森幸男.
    Therapeutic Res, 2003, Not refereed, Not invited
    Lead
  • Characterization of Ca2+ signaling pathways in human mesenchymal stem cells
    S Kawano; S Shoji; S Ichinose; K Yamagata; M Tagami; M Hiraoka
    CELL CALCIUM, Oct. 2002, Refereed, Not invited
  • Differential regulation of glial cell line-derived neurotrophic factor (GDNF) mRNA expression during hypoxia and reoxygenation in astrocytes isolated from stroke-prone spontaneously hypertensive rats
    K Yamagata; M Tagami; K Ikeda; S Tsumagari; Y Yamori; Y Nara
    GLIA, Jan. 2002, Refereed, Not invited
    Lead
  • Ischemic neuronal death and its prevention by antioxidants.
    Yamagata K; Tagami M; Nara Y; and Yamori Y.
    Curr Top Pharmacol, 2002, Refereed, Not invited
    Lead
  • Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats
    T Noguchi; K Ikeda; Y Sasaki; J Yamamoto; J Seki; K Yamagata; Y Nara; H Hara; H Kakuta; Y Yamori
    HYPERTENSION RESEARCH, Nov. 2001, Refereed, Not invited
  • Nutritional pathogenesis and prevention of stroke
    Y Yamori; K Ikeda; M Tagami; K Yamagata; Y Nara
    NUTRITION AND BRAIN, 2001, Refereed, Not invited
  • ビタミンE による神経細胞アポトーシスの予防.
    医学のあゆみ, 2001, Refereed, Not invited
    Lead
  • 脳卒中ラット(SHRSP)における脳虚血再潅流時の脳血流量変化と海馬領域一酸化窒素産生
    野口孝則、池田克巳、奈良安雄、家森幸男
    脳循環代謝, 2001, Not refereed, Not invited
  • Reduced production of lactate during hypoxia and reoxygenation in astrocytes isolated from stroke-prone spontaneously hypertensive rats
    K Yamagata; M Tagami; K Ikeda; T Noguchi; Y Yamori; Y Nara
    NEUROSCIENCE LETTERS, Dec. 2000, Refereed, Not invited
    Lead
  • Altered gene expressions during hypoxia and reoxygenation in cortical neurons isolated from stroke-prone spontaneously hypertensive rats
    K Yamagata; M Tagami; K Ikeda; Y Yamori; Y Nara
    NEUROSCIENCE LETTERS, Apr. 2000, Refereed, Not invited
    Lead
  • Nitric oxide synthase and Bcl-2 expression in apoptosis of hippocampal neurons in stroke-prone spontaneously hypertensive rats after cerebral ischemia and reperfusion.
    T Noguchi; K Ikeda; K Yamagata; Y Nara; Y Yamori
    BIOLOGY OF NITRIC OXIDE, PT 7, 2000, Refereed, Not invited
  • 高血圧性脳血管障害におけるアストロサイトの役割.
    田上幹樹; 山形一雄
    細胞, 2000, Refereed, Not invited
    Last
  • 脳卒中易発症高血圧自然発症ラット海馬における脳虚血再潅流時の酸化ストレスとアポトーシスに関する研究
    野口孝則、池田克巳、奈良安雄、家森幸男
    血圧, 2000, Not refereed, Not invited
  • Vitamin E prevents apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats
    M Tagami; K Ikeda; K Yamagata; Y Nara; H Fujino; A Kubota; F Numano; Y Yamori
    LABORATORY INVESTIGATION, May 1999, Refereed, Not invited
  • Genetic vulnerability of cortical neurons isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion
    M Tagami; K Yamagata; K Ikeda; H Fujino; Y Nara; K Nakagawa; A Kubota; F Numano; Y Yamori
    HYPERTENSION RESEARCH-CLINICAL AND EXPERIMENTAL, Mar. 1999, Refereed, Not invited
  • Vitamin E prevents apoptosis in cortical neurons during hypoxia and oxygen reperfusion
    M Tagami; K Yamagata; K Ikeda; Y Nara; H Fujino; A Kubota; F Numano; Y Yamori
    LABORATORY INVESTIGATION, Nov. 1998, Refereed, Not invited
  • Faulty induction of blood-brain barrier functions by astrocytes isolated from stroke-prone spontaneously hypertensive rats
    K Yamagata; M Tagami; Y Nara; H Fujino; A Kubota; F Numano; T Kato; Y Yamori
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Sep. 1997, Refereed, Not invited
    Lead
  • Astrocyte-conditioned medium induces blood-brain barrier properties in endothelial cells
    K Yamagata; M Tagami; Y Nara; M Mitani; A Kubota; H Fujino; F Numano; T Kato; Y Yamori
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Sep. 1997, Refereed, Not invited
    Lead
  • Insulin-like growth factors prevent apoptosis in cortical neurons isolated from stroke-prone spontaneously hypertensive rats
    M Tagami; K Yamagata; Y Nara; H Fujino; A Kubota; F Numano; Y Yamori
    LABORATORY INVESTIGATION, May 1997, Refereed, Not invited
  • Ultrastructural analysis of survival in cultured smooth muscle cells isolated from stroke-prone spontaneously hypertensive rats: Effect of growth factors
    M Tagami; K Yamagata; Y Nara; H Fujino; A Kubota; F Numano; Y Yamori
    CELL AND TISSUE RESEARCH, Aug. 1996, Refereed, Not invited
  • Astrocytic contributions to blood-brain barrier (BBB) formation by endothelial cells: A possible use of aortic endothelial cell for in vitro BBB model
    Ichiro Isobe; Takao Watanabe; Toshihisa Yotsuyanagi; Norio Hazemoto; Kazuo Yamagata; Takatoshi Ueki; Keiko Nakanishi; Kiyofumi Asai; Taiji Kato
    Neurochemistry International, 1996, Refereed, Not invited
  • DEMONSTRATION OF HEREDITARILY ACCELERATED PROLIFERATION IN ASTROCYTES DERIVED FROM SPONTANEOUSLY HYPERTENSIVE RATS
    K YAMAGATA; Y NARA; M TAGAMI; Y YAMORI
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Sep. 1995, Not refereed, Not invited
    Lead
  • 高血圧性脳障害におけるastrocytesの役割 : in vitro モデル系の確 立と脳障害発症機序解析への応用.
    山形一雄
    東邦医学会誌, 1995, Refereed, Not invited
    Lead
  • HUMAN NEUROBLASTOMA GROWTH-INHIBITORY FACTOR (H-NGIF), DERIVED FROM HUMAN ASTROCYTOMA CONDITIONED MEDIUM, HAS NEUROTROPHIC PROPERTIES
    YZ EKSIOGLU; J IIDA; K ASAI; T UEKI; K NAKANISHI; ISOBE, I; K YAMAGATA; T KATO
    BRAIN RESEARCH, May 1994, Refereed, Not invited
  • MORPHOLOGICAL-DIFFERENTIATION OF ENDOTHELIAL-CELLS COCULTURED WITH ASTROCYTES ON TYPE-I OR TYPE-IV COLLAGEN
    M TAGAMI; K YAMAGATA; H FUJINO; A KUBOTA; Y NARA; Y YAMORI
    CELL AND TISSUE RESEARCH, May 1992, Refereed, Not invited
  • DIFFERENTIATION OF ASTROCYTES AND ENDOTHELIAL-CELLS MAINTAINED IN COCULTURE TECHNIQUES
    M TAGAMI; K YAMAGATA; H FUJINO; Y YAMORI
    ELECTRON MICROSCOPY II, 1992, Refereed, Not invited
  • EXAMINATION OF ASTROCYTIC FUNCTIONS IN STROKE-PRONE SHR APPLYING COCULTURE TECHNIQUES
    M TAGAMI; K YAMAGATA; Y NARA; Y YAMORI
    GENETIC HYPERTENSION, 1992, Refereed, Not invited
  • NGIF, A neuroblastoma growth inhibitory factor from human astrocytoma with neurotrophic properties.
    Eksioglu Y Z; Iida J; Yamagata K; Asai K; and Kato K.
    Bul Jap Neurochem, 1992, Refereed, Not invited
  • Analysis of detalied disease processes of cerebral endothelia, pericytes and astrocytes using stroke-pron SHR and cultured astrocytes.
    Tagami M; Tukada T; Kubota A; Yamagata K; Nara Y; and Yamori Y.
    Clin Eex Hypertention, 1990, Refereed, Not invited
  • INDUCTION BY FIBROBLAST GROWTH-FACTOR OF ANGIOTENSIN CONVERTING ENZYME IN VASCULAR ENDOTHELIAL-CELLS INVITRO
    T OKABE; K YAMAGATA; M FUJISAWA; F TAKAKU; H HIDAKA; Y UMEZAWA
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jun. 1987, Refereed, Not invited
  • LIPID AND TRIACYLGLYCEROL COMPOSITIONS OF TOTAL LIPIDS IN PUMPKIN SEEDS
    H TSUYUKI; S ITOH; K YAMAGATA
    JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI, 1985, Refereed, Not invited
    Last
  • ヒト抹消 monocytesリポ蛋白リパーゼ (LPL) 分泌能について.
    村瀬敏郎; 岡部哲朗; 山形一雄; 山田信博; 高久文麿 他
    動脈硬化, 1984, Refereed, Not invited
  • INCREASED ANGIOTENSIN CONVERTING ENZYME IN PERIPHERAL-BLOOD MONOCYTES FROM PATIENTS WITH SARCOIDOSIS
    T OKABE; K YMAMAGATA; M FUJISAWA; J WATANABE; F TAKAKU; JJ LANZILLO; BL FANBURG
    CLINICAL RESEARCH, 1984, Refereed, Not invited
  • 活性型レニン及び不活性型レニンの測定法の改良.
    山形一雄; 丸山昭治; 石戸利貞
    臨床検査, 1982, Refereed, Not invited
    Lead

MISC

  • Spontaneous Ca2+ oscillation induces membrane fluctuation in human mesenchymal stem cells
    S Kawano; K Otsu; S Shoji; K Yamagata; M Hiraoka
    BIOPHYSICAL JOURNAL, Feb. 2003, Not refereed, Not invited
  • Vitamin E prevents apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats
    M Tagami; K Ikeda; K Yamagata; Y Nara; A Kubota; Y Yamori
    STROKE, Jan. 1998, Not refereed, Not invited

Books and other publications

  • (Chapter title) Main coffee polyphenols: chlorogenic, ferulic, and caffeic acids. (Book title) Coffee and human health: Chemistry and mechanisms of action.
    Kazuo Yamagata, Single work, Chapter, Yamagata K.
    The Royal Society of Chemistry (RSC), Jul. 2023, Refereed
    9781839163852
  • (Chapter title) Dietary lipids, effect of docosahexaenoic acid on stroke-related neuronal damage. (Book title) Nutrition and Neurological Disorders.
    Kazuo Yamagata, Single work, Chapter, Yamagata K.
    Elsevier, May 2023, Refereed
    9780323898348
  • (Chapter title) The effects of nut consumption on the inhibition of obesity-related endothelial cell dysfunction and prevention of cardiovascular diseases. (Book title) Studies in Natural Product Chemistry (Bioactive Natural Products)
    Yamagata K., Single work, Chapter 1. p1-39, Yamagata K.
    Elsevier, Oct. 2022, Refereed
    9780323912501
  • (Chapter title) Effects of chlorogenic acid: Inhibition of obesity-induced vascular endothelial dysfunction and prevention of metabolic syndrome development. (Book title) Chlorogenic Acid: Properties, Sources and Health Effects.
    Single work, Yamagata K
    Nova Science Publishers, Inc., Oct. 2021, Refereed
  • (Chapter title) Effects of dietary n-3 polyunsaturated fatty acids on cardiovascular disease. (Book title) Studies in Natural Products Chemistry Vol. 64 (Bioactive Natural Products)
    Yamagata Kazuo, Single work, Chapter 7 Vol 64 Page 217-240, Yamagata K.
    Elsevier, Feb. 2020, Refereed
    9780128179031
  • Prevention of vascular endothelial dysfunction by polyphenols: role in cardiovascular disease prevention.Book title; Phytopharmaceuticals: Potential Therapeutic Applications.
    Yamagata Kazuo, Single work, Chapter 11 Page 223-246, Yamagata K.
    Wiley-Scrivener, Feb. 2020, Refereed
    9781119681915
  • (Chapter title) Dietary soybean isoflavones in lifestyle-related disease prevention. Book title; Phytochemicals: Plant Sources and Potential Health Benefits.
    Yamagata Kazuo, Single work, Page 53-90, Yamagata K.
    Nova Science Publishers,Inc, Apr. 2019, Refereed
    9781536154788
  • (Chapter title) Effects of dietary polyphenols on chronic diseases: Epidemiological data and molecular mechanisms of action. (Book title) Frontiers in Natural Product Chemistry Vol. 5
    Yamagata Kazuo, Single work, Chapter 3 Page 55-94, Yamagata K.
    Bentham Science Publishers, Apr. 2019, Refereed
    9789811423765
  • (Chapter title) Metabolic syndrome: preventive effects of dietary flavonoids. (Book title) Studies in Natural Products Chemistry (Bioactive Natural Products).
    Yamagata Kazuo, Single work, Chapter 1 p1-28, Yamagata Kazuo
    Elsevier, Dec. 2018, Not refereed
    9780444641816
  • (Title) Do coffee polyphenols have a preventive action on metabolic syndrome associated endothelial dysfunctions ? an assessment of the current evidence. Book title; Dietary Antioxidants and Prevention of Non-Communicable Diseases.
    Yamagata Kazuo, Single work, p126-143, Yamagata Kazuo
    MDPI, Sep. 2018, Refereed
    9783038972266
  • (Chapter title) Insight into dietary epigallocatechin-3-gallate for endothelial dysfunction. (Book title) Advancements in Endothelial Dysfunction Research
    Yamagata Kazuo, Single work, Chapter 4 p99-124, Yamagata Kazuo
    Nova Science Publishers, Inc, Jul. 2018, Refereed
    9781536139518
  • (Chapter title) Endothelial protective effects of dietary phytochemicals: focus on polyphenols and carotenoids. (Book title) Studies in Natural Products Chemistry 55 (Bioactive Natural Products).
    Yamagata Kazuo, Single work, Chapter 10 p323-350, Yamagata Kazuo
    Elsevier, Dec. 2017, Refereed
    9780444505880
  • (Chapter title) Carotenoids regulate endothelial functions and reduce the risk of cardiovascular disease. (Book title) Carotenoids, Editer, Dragan Cvetkovic
    Yamagata Kazuo, Single work, Chapter 7 p105-121, Yamagata Kazuo
    In Tech, Apr. 2017, Refereed
    9789535153078
  • (Chapter title) Preventive properties of green tea catechins against metabolic syndrome. (Book title) Epicatechin: Sources, Effects and Research.
    Yamagata Kazuo, Single work, Chapter 2 p43-69, Yamagata Kazuo
    Nova Science Publishers, Inc, Apr. 2017, Refereed
    9781536117943
  • (Chapter title) Role of scavenger receptors in the development of atherosclerosis and the preventative effects of dietary components. (Book title) In Advances in Medicine and Biology.Volume 108, Editors: Leon V. Berhardt,
    Yamagata Kazuo, Single work, Chapter 7 p127-151, Yamagata Kazuo
    Nova Science Publishers, Inc., Dec. 2016, Refereed
    9781536101355
  • (Chapter title) Cerebral ischemia induces neuronal vulnerability and astrocytic dysfunction in stroke-prone spontaneously hypertensive rats. in “ Ischemic stroke - updates”.
    Yamagata Kazuo, Single work, Chapter 3 p43-58, Yamagata Kazuo
    Intech, Nov. 2016, Refereed
    9789535127130
  • (Chapter title) Protective effects of docosahexaenoic acid on vascular endothelial dysfunction and cardiovascular disease. Book title; Docosahexaenoic Acid (DHA): Properties, Function and Health Effects.
    Yamagata Kazuo, Single work, Chapter 4 p119-140., Yamagata Kazuo
    Nova Science Publishers,Inc., Sep. 2016, Refereed
  • Stroke-prone spontaneously hypertensive rats: insights on neuronal vulnerability and astrocytic abnormalities on stroke. Book title; Advances in Medicine and Biology. Volume 96, Chapter 8, Editors; Leon V. Berhardt.
    Yamagata Kazuo, Single work, Chapter 8 p115-132, Yamagata Kazuo
    Nova Science Publishers,Inc., Mar. 2016, Refereed
    1634845064
  • Prevention of ischemia-induced neuronal apoptosis by vitamin E in stroke-prone spontaneously hypertensive rats-cellular mechanisms of antioxidant. Bioactive nutriceuticals and food supplements in neurological and brain disease: prevention and therapy.
    Yamagat K; Tagami M, Joint work, Chapter 41 pp399-402, Yamagat K; Tagami M.
    Elsevier Science & Technology Books, Oct. 2014, Refereed
    9780124114623
  • ビタミンE -大豆の栄養成分と機能性
    山形 一雄, Single work, pp71-78, 山形 一雄
    シーエムシー出版, Aug. 2014, Not refereed
    9784781309491
  • Effect of tocopherol on the ischemia-reperfusion injury of the brain (Tocopherol: Sources, Uses and Health BenefitsEdits, Angel Catala)
    Yamagata K; Yamori Y, Joint work, pp 193–205, Yamagata K and Yamori Y
    Nova Science Publishers, Inc., Dec. 2012, Refereed
    9781621007043
  • Ischemic neurodegeneration in stroke-prone spontaneously hypertensive rats and its prevention with antioxidants such as polyphenols (Advances in the Preclinical Study of Ischemic Stroke, Edited by Maurizio Balestrino) Published online: 16 March, 2012
    Yamagata K, Single work, pp 1-20, Yamagata K
    InTech, Jan. 2012, Refereed
    9789535102908
  • Fatty Acid Induce Tight Junctions in Brain Capillary Endothelial Cells.(Microvascula Research: Biology and Pathology)
    Yamagata K; Tagami M; Nara Y; Yokogoshi H; Yamori Y, Joint work, Volume 2 Chapter 65 pp411-414, Yamagata K; Tagami M; Nara Y; Yokogoshi H; Yamori Y.
    Elsevier, May 2006, Refereed
  • Nutritional Pathogenesis and Prevention of Stroke.(Nestle Nutrition Workshop Series, Clin Perform Programme)
    Yamori Y; Ikeda K; Tagami M; Yamagata K; Nara Y, Joint work, pp 231-244, Yamori Y; Ikeda K; Tagami M; Yamagata K; and Nara Y.
    Karger, May 2001, Not refereed
  • Genetic Hypertention-Examination of astrocytic functions in stroke-pron SHR applyling co-culture techniques.
    Tagami M; Yamagata K; Nara Y; Yamori Y, Joint work, pp 603-605., Tagami M; Yamagata K; Nara Y; and Yamori Y.
    John Libbey Eurotext Ltd, Feb. 1992, Not refereed

Lectures, oral presentations, etc.

  • 脳卒中易発症性高血圧自然発症ラット(SHRSP)由来in vitro BBB モデルの再構築と機能評価
    中川 慎介、大原 浩貴、有賀 純、丹羽 正美、山形 一雄、並河 徹
    日本薬理学会第93年会, Mar. 2020
  • オレイン酸及びその代謝物オレオイルエタノールアミドのアポトーシス及び免疫チェックポイント関連遺伝子の発現に対する影響
    日本薬学会第139年会 (千葉), Mar. 2019, Not invited
  • 食品成分の肝細胞障害刺激に対する予防特性
    日本薬学会第138年会 (金沢), Mar. 2018, Not invited
  • 地中海料理に含まれる食品成分のヒト肺がん細胞株に対する影響
    日本薬学会第138年会 (金沢), Mar. 2018, Not invited
  • WKY/IzmとSHRSP/Izmの血液脳関門機能比較 In vitro BBBモデルを用いた検討
    第53回 高血圧関連疾患モデル学会, Nov. 2017, 高血圧関連疾患モデル学会, Not invited
  • 生活習慣病に関連した刺激による肝細胞障害誘導と食品成分の影響
    日本薬学会第137年会, Mar. 2017, Not invited
  • ヒト脂肪細胞における分化および腫瘍壊死因子-αで誘導されるアディポサイトカインの発現とα-マ ンゴスチンの影響
    日本薬学会第137年会, Mar. 2017, Not invited
  • イソフラボン複合サプリメントのIshikawa細胞におけるLIF、TGFβなどの遺伝子発現に対する作用
    日本薬学会第136年会, Mar. 2016, Not invited
  • TNFαによる血管内皮細胞の機能不全及び老化誘導に対するドコサヘキサエンの予防作用
    日本薬学会第136 年会, Mar. 2016, Not invited
  • ヒト脂肪細胞株の分化刺激と炎症刺激に対するα-マンゴスチンの影響
    日本薬学会第136 年会, Mar. 2016, Not invited
  • 生活習慣病に関連する刺激で誘導される血管内皮障害と老化誘導およびDHAの予防効果
    日本薬学会第135年会, Mar. 2015, Not invited
  • 緑茶成分EGCGとテアニンの血管内皮細胞障害に対する阻止作用-内皮機能とオートフージーの関与
    日本薬学会第134年会, Mar. 2014, Not invited
  • ヒト血管内皮細胞における食品成分のHDL 様刺激作用
    日本薬学会第131年会 (震災の為、申請のみ), Mar. 2011, Not invited
  • 血管内皮細胞障害における血管新生に関する遺伝子発現と植物成分の影響
    日本薬学会第130回年会, Mar. 2010, Not invited
  • フラボノイドの誘導LOX-1の遺伝子発現に対する抑制作用
    第84回日本栄養・食糧学会関東支部会, Sep. 2009, Not invited
  • 高グルコース刺激によるAT1受容体、LOX-1等の遺伝子発現とフラボノイドによる修飾
    日本薬学会第129回年会, Mar. 2009, Not invited
  • ヒト血管内皮細胞における接着分子およびタイトジャンクション関連遺伝子の発現誘導とフラボノイドによる修飾作用
    日本薬学会第128回年会, Mar. 2008, Not invited
  • ファイトケミカルの酸化ストレス障害に対する予防特性
    日本食品科学工学会第53回大会, Aug. 2006, Not invited
  • アストロサイト由来神経栄養因子-L-セリンの脳損傷時の神経細胞に対する役割の解明
    日本農芸化学大会, Aug. 2005, Not invited
  • SHRSP由来アストサイトにおけるGDNFの発現変異
    第30回 関西高血圧研究会, Jan. 2003, Not invited
  • ミニレビュー 脳循環代謝と一酸化窒素
    日本高血圧自然発症ラット学会総会第38回年会, Oct. 2002, Not invited
  • SHRSP由来アストサイトにおける低酸素/再酸素化に伴うGDNFの発現
    日本高血圧自然発症ラット学会総会第38回年会, Oct. 2002, Not invited
  • Ca2+ signalling pathways in human mesenchymal stem cells.
    Kawano S; Shoji S; Tagami M; Yamagata K; Ichinose S; Hiraoka M.
    Scientific Meeting of the International Society of Biophysical Society. (USA), 2002, Not invited
  • Alterd nitric oxide synthase expression in hippocampus caused by cerebral ischemia and reperfusion in genetic hypertensive rats.
    Ikeda K; Noguchi T; Negishi H; Yamagata K; Nara Y; Xu J; Yamori Y.
    19th Scientific Meeting of the International Society of Hypertention. Jointed 12th European Meeting of Hypertension. (Prague, Czech Repubic), 2002, Not invited
  • シンポジウム「脳卒中ラット(SHRSP)の本態にせまる」S-II-2. SHRSPの人工的虚血再灌流におけ る遺伝子発現
    日本高血圧自然発症ラット学会総会第37回, Oct. 2001, Not invited
  • ヒト間葉系幹細胞のイオンチャンネルの発現とCa2+動態
    日本生理学会総会第78回, Mar. 2001, Not invited
  • Changes in nitric oxide production in hippocampus and cerebral blood flow caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats.
    Noguchi T; Ikeda K; Yamagata K; Nara Y; Yamori Y.
    10th International symposium on SHR and related studies.(Germany), 2001, Not invited
  • Cytokines accelerate expression of cell adhesion molecules in cultured astrocytes from stroke-prone spontaneously hypertensive rats (SHRSP/Izm).
    Nara Y; Yamagata K; Higuchi Y; Tagami M; Ikeda K; Katano S; Yamori Y; Miki T.
    10th International symposium on SHR and related studies.(Germany), 2001, Not invited
  • 脳卒中易発症高血圧自然発症ラット海馬における脳虚血再灌流時の一酸化窒素産生と脳血流量の変化
    日本高血圧学会総会第23 回総会, Oct. 2000, Not invited
  • 脳卒中易発症高血圧自然発症ラット(SHRSP/Izm)海馬における脳虚血再灌流時の一酸化窒素産生と脳血流量の変化
    日本高血圧自然発症ラット学会第36回総会, Jul. 2000, Not invited
  • 降圧剤による細胞傷害の予防-酸素 radical 消去の観点から
    日本高血圧学会第22 回 総会, Oct. 1999, Not invited
  • 脳卒中易発症高血圧自然発症ラット海馬における脳虚血再灌流時のアポトーシス関連遺伝子発現の変化
    日本高血圧自然発症ラット学会第35回総会, Aug. 1999, Not invited
  • 脳卒中易発症ラット(SHRSP) 由来培養神経細胞の酸化ストレスに対する脆弱性と細胞内還元状態に関する研究
    日本高血圧自然発症ラット学会総会, Aug. 1999, Not invited
  • ブタ顆粒膜細胞の卵胞発育段階におけるサ イトカインの影響
    日本繁殖生物学会第91回総会, Aug. 1998, Not invited
  • Vitamin E prevents apoptosis in hipocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats.
    Tagami M; Ikeda K; Yamagata K; Nara Y; Kubota A; Yamori Y.
    23th International Joint Conference on Stroke and Cerebral Circulation. (Florida, USA), 1998, Not invited
  • Vulnerability of cultured vascular smooth muscle cells (SMC) from stroke-pron SHR (SHRSP) to hypoxic conditions.
    Nara Y; Ito T; Ikeda K; Yamagata K; Sawamura M; Yamori Y
    17th Scientific Meeting of the International Society of Hypertention. (Amsterdam, Netherlands), 1998, Not invited
  • Vitamin E prevents apoptosis in cortical neurons and astrocytes isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxigen reperfuson.
    Tagami M; Yamagata K; Ikeda K; Nara Y; Kubota A; Yamori Y.
    17th Scientific Meeting of the International Society of Hypertention.(Amsterdam, Netherlands), 1998, Not invited
  • Vitamin EはSHRSP由来神経細胞の虚血-再灌流によるアポトーシスを完全に抑制する
    日本高血圧学会第20 回 総会, Oct. 1997, Not invited
  • Vitamin E prevents apoptosis from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion.
    Tagami M; Yamagata K; Ikeda K; Nara Y; Kubota A; Yamori Y.
    9th International symposium on SHR and related studies.(Montoriol, Canada), 1997, Not invited
  • マウスLeydig腫瘍株MLTC-1のホルモン反応性
    日本繁殖生物学会第90回総会, Oct. 1996, Not invited
  • マウスライデッヒ細胞株を用いたLH測定法の検討
    日本獣医学会第122回総会, Aug. 1996, Not invited
  • 遺伝的脳卒中発症機構の研究:アポトーシスの関与
    日本病理学会第85回総会, Apr. 1996, Not invited
  • Genetic vulnerability of cultured cortical neurons isolated from stroke-pron SHR.
    Tagami T; Yamagata Y; Nara Y; Kubota A; Numano F; and Yamori Y.
    15th Scientific Meeting of the International Society of Hypertention. (Glasgow, U.K), 1996, Not invited
  • SHRSP由来培養神経細胞の病理組織学的検討
    日本高血圧自然発症ラット学会第31回総会, Oct. 1995, Not invited
  • 血管内皮細胞、アストロサイト、神経細胞のco-cultureによる研究
    日本動脈硬学会第26回総会, Nov. 1994, Not invited
  • Growth factors attenuate the hereditary weakness of vascular smooth muscle cells derived from stroke-prone SHR
    Tagami T; Yamagata Y; Numano F; Nara Y; Kubota A; and Yamori; Y.
    15th Scintific Meeting of the International Society of Hypertention. (Melbourune, Australia), 1994, Not invited
  • NGIF, A neuroblastoma growth inhibitory factor from human astrocytoma with neurotrophic properties
    日本神経化学会第36回総会, Oct. 1993, Not invited
  • 高血圧性脳血管障害の発症機序に関する検討 -脳卒中の遺伝的成因に関する新知見-
    日本高血圧学会第16回総会, Oct. 1993, Not invited
  • SHRSP由来培養平滑筋細胞の脆弱性に関する検討
    日本高血圧自然発症ラット学会総会, Sep. 1993, Not invited
  • 血管内皮細胞とアストロサイトのco-cultureによる研究(続報)
    日本動脈硬化学会第25回総会, May 1993, Not invited
  • 血液脳関門に対するアストロサイトの影響-in vitroモデル系による検討
    日本生化学会総会, Oct. 1992, Not invited
  • Demonstration of deteriorated astrocytic functions in stroke-pron SHR using co-culture techniques.
    Tagami M; Yamagata K; Nara Y; and Yamori Y.
    14th Scientific Meeting of the International of Hypertention. (Madrid, Spain), 1992, Not invited
  • Differentiation of astrocytes and endothelial cells maintains in co-culture techniques.
    Tagami M; Yamagata Y; Fujino H; and Yamori Y.
    5th Asia-Pacific Electron Microscope Conference. (Beijng, China), 1992, Not invited
  • 血管内皮細胞とアストロサイトのco-cultureによる研究-各種培養条件による検討-
    日本病理学会第80回総会, Apr. 1991, Not invited
  • Examination of astrocytes function in stroke-pron SHR applying co-culture techniques.
    Tagami M; Yamagata K; Nara Y; and Yamori Y.
    7th International symposium on SHR and related studies. (Lyon, France), 1991, Not invited
  • 血管内皮細胞とアストロサイトのフco-cultureによる研究
    日本脈管学会第31回総会, Oct. 1990, Not invited
  • 血管内皮細胞とアストロサイトのco-cultureによる研究-内皮細胞透過性の検討-
    日本病理学会第79回総会, Oct. 1990, Not invited
  • 高血圧性脳障害発生過程における内皮細胞、周細胞、神経膠細胞の病態に関する電顕的、免疫組織化学的、組織培養学的研究
    日本高血圧学会第12回総会, Aug. 1989, Not invited
  • Charactaristics of cultured astroglia cells (AGC) from fetal brain stroke-pron SHR (SHRSP).
    Nara Y; Yamagata K; Ishinaga T; Yamada K; Yamagata K; Nishino T; Mori C; and Yamori Y.
    6th International Symposium on SHR and Related Studie (Iowa,USA), 1989, Not invited
  • Basic abnormalityies of astroglia cells (AGC) for hypertensive cerebrovascular diseases in stroke-prone SHR (SHRSP).
    Yamagata K; Nara Y; Yamada K; Mano M; Kobayashi A; Horie; R.and YamoriY.
    12th Scientific Meeting of the International Society of Hypertention.(Kyoto, Japan), 1988, Not invited
  • Roles of protein kinase C (PKC) and oncogene expressin in growth control of vascular smooth muscle cells (VSMC).
    Nabika T; Yamagata K; Nara Y. and Yamori Y.
    12th Scientific Meeting of the International Society of Hypertention.(Kyoto, Japan), 1988, Not invited
  • Na-H exchange activity in vascular smooth muscle cells of stroke-pron SHR.
    Kobayashi A; Nara Y; Yamada K; Yamagata K; Nishino T; Mori; C.and Yamori Y.
    12th Scientific Meeting of the International Society of Hypertention.(Kyoto, Japan), 1988, Not invited
  • Increased angiotensin converting enzyme in peripheral blood monocytes from patients with sarcoidosis.
    Okabe T; Yamagata K; Fuzisawa M.; Watanabe J; Takaku F; Joseph J. Lanzillo and Barry; L. Funburg.
    10th International Conferance on Sarcoidosis.(Bolltimor, U.S.A.), 1984, Not invited
  • 新しい成人病モデル動物ゲッチンゲンミニブタを用いた高血圧の作成とその病態解析
    日本内分泌学会第55 回総会, Apr. 1982, Not invited
  • ゲッチンゲンミニブタによる高血圧の作成とその病態解析に関する研究
    日本高血圧学会第4回総会, Sep. 1981, Not invited
  • Studies on the lipids in pumpkin seeds.
    Tsuyuki H; Itoh S. and Yamagata K.
    5th International Congress of Food Scinence and Technology. 1978 Abstract (Kyoto, Japan), 1978, Not invited

Affiliated academic society

  • 日本高血圧学会
  • 日本神経化学会
  • 日本細胞生物学会
  • 高血圧関連疾患モデル(SHR)学会
  • 日本生化学会
  • 日本動脈硬化学会

Research Themes

  • Study of functional foods as incretin effects for metabolic syndrome
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2014 - 31 Mar. 2017
    Negishi Hiroko
  • 科学研究費 基盤研究A (分担) 生活習慣病とフィトケミカル(植物微量成分)に関する国際共同研究
  • 科学研究費 基盤研究C (分担) 胚性幹細胞から心筋細胞への分化誘導に伴なう興奮-収縮連関機構の発現機序の検討
  • 日本大学学術研究助成金〔総合研究〕(代表) 健康長寿をめざした食品中の新規高次生理機能分子の探索とその分子機構
  • 日本大学学術研究助成金〔総合研究〕(代表) 健康長寿をめざした食品中の新規高次生理機能分子の探索とその分子機構 (継続研究)
  • 科学研究費 基盤研究C (代表) 遺伝的脳卒中モデルラットの血液脳関門は脆弱かーインビトロ再構築技術を用いた検討

Industrial Property Rights

  • 2018-039740, 2016-173115, 不妊改善剤及び当該改善剤を用いた食品
  • 特開平6-256368, 特願平5-48179, 神経芽細胞増殖抑制因子
  • 特開平7-101990, 特願平5-269794, 神経栄養因子

Social Contribution Activities

  • 100年を生きる食品の基礎知識~地中海料 理と和食の実力 (健康長寿生活のすゝめ~健康に長生きするための8ヒント)
    appearance
    藤沢市生涯学習部 生涯学習総務課 生涯学習活動推進室, 藤沢市生涯学習大学 放送通信コース, レディオ湘南 83.1 MHz, 29 Oct. 2019 - 29 Oct. 2019
  • 食品と健康長寿ー長寿食の理にかなったしくみ
    lecturer
    (一般社団法人) 湘南健康長寿研究会, 27 Jul. 2018 - 27 Jul. 2019
  • 世界長寿地域の理にかなった食生活
    lecturer
    藤沢市 湘南大庭地区郷土づくり推進会議主催事業 湘南大庭公民館事業「男性学級」共催, 藤沢市大庭公民館, 22 Dec. 2018 - 22 Dec. 2018

Media Coverage

  • 100年を生きる食品の基礎知識~地中海料 理と和食の実力 (健康長寿生活のすゝめ~健康に長生きするための8ヒント)
    藤沢市生涯学習部 生涯学習総務課 生涯学習活動推進室, 藤沢市生涯学習大学 放送通信コース, レディオ湘南 83.1 MHz, 29 Oct. 2019, Media report