HASHIZUME-TAKIZAWA Tomomi
| School of Dentistry at Matsudo Department of Dentistry | Assistant Professor |
Researcher Information
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Research activity information
Paper
- Cell wall glycosyltransferase of Streptococcus mutans impacts its dissemination to murine organs
Tomomi Hashizume-Takizawa; Taiki Ando; Ayaka Urakawa; Kazuhiro Aoki; Hedenobu Senpuku
Infection and Immunity, Mar. 2025, Refereed, Not invited
Lead - Assessment of biofilm formation on ceramic, metal, and plastic brackets in orthodontic materials by new method using renG-expressing Streptococcus mutans
Hiroyuki Kato; Hiroko Yoshida; Masanori Saito; Tomomi Hashizume-Takizawa; Shinichi Negishi; Hidenobu Senpuku
Journal of Oral Biosciences, Mar. 2025, Refereed, Not invited - Lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli: Differential and interactive effects on novelty-induced hyperlocomotion, blood cytokine levels and TLR4-related processes
Yuri Aono; Koji Saito; Hiroki Kawashima; Arata Watanabe; Tetsuro Kono; Tomomi Hashizume-Takizawa; Hiroyuki Okada; Yasuhiro Kosuge; Hidenobu Senpuku; John L. Waddington; Tadashi Saigusa
PLOS ONE, Jun. 2024, Refereed, Not invited - Effects of Adhesive or Non-adhesive Protein-immobilized Bioactive（Lactic Acid-ε-caprolactone）Films on Mouse Osteoblast-like Cells
Megumi Fuse; Tomomi Hashizume-Takizawa; Chieko Taguchi; Kou Fujita-Nakajima; Takao Kuwada-Kusunose; Hiroyuki Okada
International Journal of Oral-Medical Sciences, Dec. 2023, Refereed - Study of Bioactive Film: Fabrication of Poly(lactic acid) Film Immobilized the Tilapia Fish Collagen or Porcine Collagen and Behavior of MC3C3T-E1 Cells
M. Fuse; T. Hashizume-Takizawa; A. Watabane; C. Taguchi; K. Fujita-Nakajima; T. Kuwada-Kusunose; H. Okada
International Journal of Oral-Medical Sciences, Dec. 2022, Refereed - Editorial: Oral Microbiome and Inflammation Connection to Systemic Health
Loreto Abusleme; Ana Carolina Morandini; Tomomi Hashizume-Takizawa; Sinem Esra Sahingu
Frontiers in Cellular and Infection Microbiology, Nov. 2021, Refereed - Actinomyces capricornis sp. nov., isolated from the oral cavity of a Japanese serow
Masanori Saito; Noriko ShinozakiーKuwahara; Tomomi Hashizume-Takizawa; Hiroya Gotouda; Hidenobu Senpuku; Tomoko Kurita-Ochiai
Microbiol. Immunol., Sep. 2021, Refereed, Not invited - Lactic acid bacteria prevent both periodontitis and atherosclerosis exacerbated by periodontitis in spontaneously hyperlipidemic mice
Kobayashi; R.; Hashizume-Takizawa; T.; Kurita-Ochiai; T.
Journal of periodontal research, Aug. 2021, Refereed, Not invited - Effect of Alkaline-hydrolyzed Bioactive Poly(Lactic Acid-ε-caprolactone)Film on Apatite Precipitation in simulated Body Fluid
M. Fuse; T. Hashizume-Takizawa; C. Taguchi; K. Fujita-Nakajima; T. Kuwada-Kusunose
International Journal of Oral-Medical Sciences, Jun. 2021, Refereed, Not invited - 日本人の発酵食品に対する意識の分析：Tweetデータを用いた探索的分析
小林良喜; 古川裕康; 瀧澤智美; 落合智子
日大口腔科学, Mar. 2021, Refereed, Not invited - Oral bacteria affect the gut microbiome and intestinal immunity
Kobayashi; R.; Ogawa; Y.; Hashizume-Takizawa; T.; Kurita-Ochiai; T.
Pathogens and Disease, Apr. 2020, Refereed, Not invited - Oral challenge with Streptococcus sanguinis induces aortic inflammation and accelerates atherosclerosis in spontaneously hyperlipidemic mice
Hashizume-Takizawa; T.; Yamaguchi; Y.; Kobayashi; R.; Shinozaki-Kuwahara; N.; Saito; M.; Kurita-Ochiai; T.
Biochemical and Biophysical Research Communications, Nov. 2019, Refereed, Not invited
Lead - Distinct roles for Peyer's patch B cells for induction of antigen-specific IgA antibody responses in mice given oral recombinant Salmonella
Tomomi Hashizume-Takizawa; Naoko Shibata; Yosuke Kurashima; Hiroshi Kiyono; Tomoko Kurita-Ochiai; Kohtaro Fujihashi
International Immunology, Jul. 2019, Refereed, Not invited
Lead - Aggregatibacter actinomycetemcomitans-sensitized monocytes induce endothelial cell apoptosis
M.Hirasawa; T.Hashizume-Takizawa; M.Saito; R.Kobayashi; N.Shinozaki-Kuwahara; T.Kurita-Ochiai
International Journal of Oral-Medical Sciences, Jun. 2019, Refereed, Not invited - CCR7-deficient mice exhibit a delayed antigen-specific mucosal IgA antibody response to an oral recombinant Salmonella strain
Tomomi Hashizume-Takizawa; Ryoki Kobayashi; Osamu Tsuzukibashi; Masanori Saito; Tomoko Kurita-Ochiai
Pathogens and Disease, Apr. 2019, Refereed, Not invited
Lead - Estimation of efficient exposure time for photoconversion of the cells derived from lymphoid tissues of photoconvertible fluorescence protein transgenic mice by the heating device for bleaching of tooth surface
Tomomi Hashizume-Takizawa; Ryoki Kobayashi; Tomoko Kurita-Ochiai
日大口腔科学, Mar. 2019, Refereed, Not invited
Lead - Nasal immunization with a vaccinia virus-based pentavalent H5N1 avian influenza vaccine induces cellular immunity in the respiratory tract of mice
Tomomi Hashizume-Takizawa; Megumi Fuse; Noriko Shinozaki-Kuwahara; Masanori Saito; Ryoki Kobayashi; Tomoko Kurita-Ochiai
International Journal of Oral-Medical Sciences, Mar. 2019, Refereed, Not invited
Lead - Mucosal vaccines for oral disease
Tomoko Kurita-Ochiai; Tomomi Hashizume-Takizawa; Ryoki Kobayashi; Masafumi Yamamoto
Mucosal Vaccines: Innovation for Preventing Infectious Diseases, Jan. 2019 - Assessment of Antigen-Specific Antibody Responses Induced by Nasal Immunization with Glucosyltransferase-B
瀧澤智美、布施恵、落合智子
日大口腔科学, Jun. 2018, Refereed, Not invited
Lead - Pseudopropionibacterium rubrum sp. nov., a novel red-pigmented species isolated from human gingival sulcus
Masanori Saito; Noriko Shinozaki-Kuwahara; Osamu Tsudukibashi; Tomomi Hashizume-Takizawa; Ryoki Kobayashi; Tomoko Kurita-Ochiai
Microbiology and Immunology, Jun. 2018, Refereed, Not invited - Oral immunization with Porphyromonas gingivalis outer membrane protein and CpG oligodeoxynucleotides attenuates P. gingivalis-accelerated atherosclerosis and inflammation
Takashi Takeuchi; Tomomi Hashizume-Takizawa; Ryoki Kobayashi
Journal of Oral Biosciences, Nov. 2017, Refereed, Not invited - Attachment of mouse osteoblast-like cells onto fibronectin- or albumin-immobilized poly (lactic acid-e-caprolactone) filmes
(M.Fuse; T.Hayakawa; T.Hashizume-Takizawa; H.Suzuki; H.Wakai; M. Nakanishi; Y. Niki; H. Sung-Moon; K. Asaka; T.Kurita-Ochiai; M.Fukumoto
Journal of Oral Tissue Engineering, Sep. 2017, Refereed, Not invited - Isolation and identification methods of Rothia species in oral cavities
Osamu Tsuzukibashi; Satoshi Uchibori; Taira Kobayashi; Koji Umezawa; Chiho Mashimo; Takayuki Nambu; Masanori Saito; Tomomi Hashizume-Takizawa; Tomoko Ochiai
JOURNAL OF MICROBIOLOGICAL METHODS, Mar. 2017, Refereed, Not invited - Porphyromonas gingivalis promotes low-density lipoprotein oxidation and atherosclerosis
Tomoko Kurita-Ochiai; Tomomi Hashizume-Takizawa; Ryoki Kobayashi; Ujjal K. Bhawal; Akira Hosono; Noriko Kinukawa; Sumito Oguchi
Journal of Oral Biosciences, Feb. 2017, Refereed, Not invited - Transformation of Aggregatibacter actinomycetemcomitans with green fluorescent protein
T. Hashizume-Takizawa; N. Shinozaki-Kuwahara; T. Kurita-Ochiai
International Journal of Oral-Medical Sciences, Dec. 2015, Refereed, Not invited
Lead - Vaccine potential of heat-killed attenuated strain of Salmonella
T. Hashizume-Takizawa
International Journal of Oral-Medical Sciences, Dec. 2015, Refereed, Not invited
Lead - Toll-like receptor 5 is not essential for the promotion of secretory immunoglobulin A antibody responses to flagellated bacteria
Tomomi Hashizume-Takizawa; Masafumi Yamamoto
MICROBIOLOGY AND IMMUNOLOGY, Dec. 2015, Refereed, Not invited
Lead - MC3T3-E1 cell assay on collagen or fibronectin immobilized poly(lactic acid-e-caprolactone)film
M. Fuse; T. Hayakawa; T. Hashizume-Takizawa; R. Takeuchi; T. Kurita-Ochiai; J. Fujita-Yoshigaki; M. Fukumoto
Journal of Hard Tissue Biology, Jun. 2015, Refereed, Not invited - Aggregatibacter actinomycetemcomitans induces Th17 cells in atherosclerotic lesion
R. Jia; T. Hashizume-Takizawa; Y. Du; M. Yamamoyo; T. Kurita-Ochiai
Pathogens and Disease, Jan. 2015, Refereed, Not invited - Porphyromonas gingivalis infection enhances Th17 responses for development of atherosclerosis
Yu Cai; Ryoki Kobayashi; Tomomi Hashizume-Takizawa; Tomoko Kurita-Ochiai
ARCHIVES OF ORAL BIOLOGY, Nov. 2014, Refereed, Not invited - Sublingual Vaccine with GroEL Attenuates Atherosclerosis
M. Hagiwara; T. Kurita-Ochiai; R. Kobayashi; T. Hashizume-Takizawa; K. Yamazaki; M. Yamamoto
JOURNAL OF DENTAL RESEARCH, Apr. 2014, Refereed, Not invited - Establishment of a convenient sandwich-ELISA for direct quantification of glucosyltransferase-I: Application for dual diagnosis of dental caries
Tomomi Hashizume-Takizawa; Noriko Shinozaki-Kuwahara; Naoya Tomita; Tomoko Kurita-Ochiai
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, Apr. 2014, Refereed, Not invited
Lead - Comparison of Apolipoprotein E Knockout Mice and Spontaneously Hyperlipidemic Mice in Porphyromonas gingivalis-Induced Atherosclerosis
N. Tomita; T. Hashizume-Takizawa; T. Kurita-Ochiai
International Journal of Oral-Medical Sciences, Mar. 2014, Refereed, Not invited - Midazolam Inhibits IgE Production through Suppression of Class Switch Recombination
H. Kusama; R. Kobayashi; T. Kurita-Ochiai; T. Hashizume-Takizawa; M. Ishikawa; Y. Fujita; K. Shibutani
International Journal of Oral-Medical Sciences, Dec. 2013, Refereed, Not invited - GroELによる舌下免疫は抗原特異的調節性T細胞を誘導し、細菌誘発性アテローム性動脈硬化症を減少させる(Sublingual immunization with GroEL induces antigen-specific regulatory T cells and reduces bacteria-induced atherosclerosis)
Hagiwara Mio; Kurita-Ochiai Tomoko; Kobayashi Ryoki; Hashizume-Takizawa Tomomi; Yamamoto Masafumi
日本免疫学会総会・学術集会記録, Nov. 2013 - Nasal immunization with the 40-kDa outer membrane protein of Porphyromonas gingivalis plus cholera toxin induces protective immunity in aged mice
Yu Cai; Tomoko Kurita-Ochiai; Ryoki Kobayashi; Tomomi Hashizume; Masafumi Yamamoto
JOURNAL OF ORAL SCIENCE, Jun. 2013, Refereed, Not invited - Functional balance between Th17, Th1, and Treg Cells in A. actinomycetemcomitans-Accelerated Atherosclerosis
R. Jia; T. Kurita-Ochiai; T. Hashizume-Takizawa; R. Kobayashi; M. Yamamoto
International Journal of Oral-Medical Sciences, Jun. 2013, Refereed, Not invited - Serum antibodies against Porphyromonas gingivalis GroEL are insufficient to induce P. gingivalis-accelerated atherosclerosis
M. Hagiwara; T. Kurita-Ochiai; T. Hashizume-Takizawa; M. Suemitsu; K. Kuyama; H. Yamamoto; K. Yamazaki; Y. Akimoto; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2013, Refereed, Not invited - Characterization of inflammation-derived CD11c+ dendritic cells in mouse model of periodontal disease
R. Kobayashi; T. Ochiai; T. Hashizume-Takizawa; K. Fujihashi; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2013, Refereed, Not invited - Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis
Y. Cai; T. Kurita-Ochiai; T. Hashizume; M. Yamamoto
FEMS Pathogens and Disease, Feb. 2013, Refereed, Not invited - Nasal immunization with the 40-kDa outer membrane protein of Porphyromonas gingivalis plus cholera toxin induces protective immunity in aged mice.
Y. Cai; Tomoko Kurita-Ochiai; Ryoki Kobayashi; Tomomi Hashizume; Masafumi Yamamoto
Journal of oral science, 2013 - Oxidative modification of lipoprotein by periodontopathic bacteria
T. Kurita-Ochiai; R. Jia; T. Hashizume; M. Yamamoto
IMMUNOLOGY, Sep. 2012, Not refereed, Not invited - A feasible enzyme-linked immunosorbent assay system using monoclonal and polyclonal antibodies against glucosyltransferase-B from Streptococcus mutans
N. Shinozaki-Kuwahara; T. Hashizume-Takizawa; M. Hirasawa; K. Takada
Hybridoma, Jun. 2012, Refereed, Not invited - Porphyromonas gingivalis accelerates atherosclerosis in C57BL/6 mice fed a high-fat diet
A. Fukasawa; T. Kurita-Ochiai; T. Hashizume; R. Kobayashi; Y. Akimoto; M. Yamamoto
Immunopharmacology and Immunotoxicology, Apr. 2012, Refereed, Not invited - Sublingual vaccination with fusion protein consisting of the functional domain of hemagglutinin A of Porphyromonas gingivalis and Escherichia coli maltose-binding protein elicits protective immunity in the oral cavity
S. Yuzawa; T. Kurita-Ochiai; T. Hashizume-Takizawa; R. Kobayashi; Y. Abiko; M. Yamamoto
FEMS Immunology and Medical microbiology, Apr. 2012, Refereed, Not invited - Correlation between the amount of glucosyltransferase-B and the decayed, missing and filled teeth index in oral samples
T. Hashizume; N. Shinozaki-Kuwahara; T. Kurita-Ochiai; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2012, Refereed, Not invited
Lead - Nasal vaccination with a fusion protein of hemagglutinin A antigenic region and maltose-binding protein elicits CD4+ T cell responses via Toll-like receptor 4
Y. Du; T. Hashizume; T. Kurita-Ochiai; Y. Abiko; T. Ikeda; A. Tsurumi; N. Tomita; M. Yamamoto
International Journal of Oral-Medical Sceinces, Mar. 2012, Refereed, Not invited - Glucosyltransferase-I is capable of functioning as an adjuvant to promote immune responses against the co-administered protein glucosyltransferase-B
S. Yuzawa; T. Hashizume; R. Kobayashi; T. Kurita-Ochiai; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2012, Refereed, Not invited - Intranasal immunization with Porphyromonas gingivalis outer membrane protein inhibits P. gingivalis-induced atherosclerosis in C57BL/6 mice fed a high-fat diet
A. Fukasawa; T. Kurita-Ochiai; T. Hashizume; R. Kobayashi; Y. Akimoto; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2012, Refereed, Not invited - Porphyromonas gingivalis stimulates monocyte adhesion to human umbilical vein endothelial cells
T. Hashizume; T. Kurita-Ochiai; M. Yamamoto
FEMS Immunology and Medical microbiology, Jun. 2011, Refereed, Not invited
Lead - A Fusion Protein of the Hemagglutinin A Antigenic Region of Porphyromonas gingivalis and Maltose-Binding Protein Induces Antibody Responses in the Oral Cavity
Y. Du; T. Hashizume; T. Kurita-Ochiai; S. Yuzawa; Y. Abiko; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2011, Refereed, Not invited - T Helper Cytokine Responses Induced by Nasal Immunization with Glucosyltransferase-I of Streptococcus sobrinus
K. Watanabe; T. Hashizume; T. Kurita-Ochiai; Y. Akimoto; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2011, Refereed, Not invited - Nasal Immunization with a Fusion Protein of Hemagglutinin A Antigenic Region and Maltose-Binding Protein Elicits CD11c+CD8+ Dendritic Cells for Induced Long-Term Protective Immunity.
Y. Du; T. Hashizume; T. Kurita-Ochiai; S. Yuzawa; Y. Abiko; M.Yamamoto
Infection and Immunity, Feb. 2011, Refereed, Not invited - Nasal Administration of Glucosyltransferase-Ⅰof Streptococcus sobrinus without Adjuvant Induces Protective Immunity
K. Watanabe; T. Hashizume; T. Kurita-Ochiai; Y. Akimoto; M. Yamamoto
Journal of Vaccines & Vaccination, Jan. 2011, Refereed, Not invited - Aggregatibacter actinomycetemcomitans accelerates atherosclerosis with an increase in atherogenic factors in spontaneously hyperlipidemic mice.
T. Zhang; T. Kurita-Ochiai; T. Hashizume; Y. Du; S. Oguchi; M. Yamamoto
FEMS Immunology & Medical Microbiology, Jul. 2010, Refereed, Not invited - T Helper Cytokine Responses Elicited by Nasal Immunization with Heat-Killed Recombinant Lactobacillus casei Expressing Outer Membrane Protein of Porphyromonas gingivalis
H. Tanaka; T. Hashizume; Y. Abiko; T. Sewaki; C. Nozaki; T. Kurita-Ochiai; M. Makimura; M. Yamamoto
International Journal of Oral-Medical Sciences, Jul. 2010, Refereed, Not invited - Oral immunization with Porphyromonas gingivalis outer membrane protein and CpG oligodeoxynucleotides elicites T helper 1 and 2 cytokines for enhanced protective immunity
C. Liu; T. Hashizume; T. Kurita-Ochiai; K. Fujihashi; M. Yamamoto
Molecular Oral Microbiology, Jun. 2010, Refereed, Not invited - Aggregatibacter Actinomycetemcomitans Leads to Endothelial Apoptosis and Atherosclerosis Development in Spontaneously Hyperlipidemic Mice
T. Zhang; T. Kurita-Ochiai; T. Hashizume; S. Oguchi; Y. Abiko; M. Yamamoto
Internatinal Journal of Oral-Medical Sciences, Mar. 2010, Refereed, Not invited - Mucosal Immunity in CD4-Deficient Mice: Direct Evidence for Mucosal IgA Antibody Responses
T. Hashizume; S. Tanaka; S. Kaminogawa; A. Hosono; K. kataoka; N. Shinozaki-Kuwahara; M. Kweon; T. Kurita-Ochiai; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2010, Refereed, Not invited
Lead - Effect of Porphyromonas gingivalis on Human Umbilical Vein Endothelial Cells
T. Hashizume; T. Kurita-Ochiai; D. Mikuni; K. kawanabe; S. Kanamaru; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2010, Refereed, Not invited
Lead - Immunogenicity and protective efficacy of killed recombinant Lactobacillus casei expressing outer membrane protein of Porphyromonas gingivalis
H. Tanaka; T. Hashizume; T. Kurita-Ochiai; Y. Abiko; M. Makimura; M. Yamamoto
International Journal of Oral-Medical Sciences, Dec. 2009, Refereed, Not invited - Sublingual vaccination with outer membrane protein of Porphyromonas gingivalis and Flt3 ligand elicits protective immunity in the oral cavity
T. Zhang; T. Hashizume; T. Kurita-Ochiai; M. Yamamoto
Biochemical and Biophysical Research Communications, Oct. 2009, Refereed, Not invited - Nasal Vaccination with an Outer Membrane Protein of Porphyromonas gingivalis and Nontoxic Chimeric Enterotoxin Adjuvant Induces Both T Helper 1 and T helper 2 Responses
F. Momoi; T. Hashizume; T. Kurita-Ochiai; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2009, Refereed, Not invited - Transcutaneous Immunization Induces a Higher Antibody Immune Responses than Parenteral Immunization
K. Ishikura; T. Hashizume; T. Kurita-Ochiai; M. Makimura; M. Yamamoto
International Journal of Oral-Medical Sciences, Mar. 2009, Refereed, Not invited - Transcutaneous Immunization with the Outer Membrane protein of P. gingivalis Elicits Long-term Protective Immunity in the Oral Cavity
K. Ishikura; T. Hashizume; T. Kurita-Ochiai; M. Makimura; M. Yamamoto
Journal of Oral Biosciences, Feb. 2009, Refereed, Not invited - Nasal Vaccination with 40-kilodalton Outer Membrane Protein of Porphyromonas gingivalis and a Nontoxic Chimeric Enterotoxin Adjuvant Induces Long-Term Protective Immunity with Reduced Levels of Immunoglobulin E Antibodies
F. Momoi; T. Hashizume; T. Kurita-Ochiai; Y. Yuki; H. Kiyono; M. Yamamoto
Infection and Immunity, Jun. 2008, Refereed, Not invited - Peyer's Patches Are Required for Intestinal Immunoglobulin A Responses to Salmonella spp.
T. Hashizume; A. Togawa; T. Nochi; O. Igarashi; M. Kweon; H. Kiyono; M. Yamamoto
Infection and Immunity, Mar. 2008, Refereed, Not invited
Lead - CpG Oligodeoxynucleotide is an Effective Adjuvant for Transcutaneous Immunization
C. Liu; T. Hashizume; T. Kurita-Ochiai; M. Yamamoto
International Journal of Oral-Medical Sciences, Dec. 2007, Refereed, Not invited - Isolated lymphoid follicles are not IgA inductive sites for recombinant Salmonella
T. Hashizume; F. Momoi; T. Kurita-Ochiai; S. Kaminogawa; A. Hosono; K. Kataoka; N. Shinozaki-Kuwahara; M. Kweon; M. Yamamoto
Biochemical and Biophysical Research Communications, Aug. 2007, Refereed, Not invited
Lead - A role of reactive oxygen species in mitochondria-, TNF-, and endoplasmic reticulum stress-mediated apoptosis induced by butyric acid
T. Kurita-Ochiai; T. Hashizume; K. Ochiai; M. Yamamoto
13TH INTERNATIONAL CONGRESS OF IMMUNOLOGY, 2007, Refereed, Not invited - Characterization of the effects of butyric acid on cell proliferation, cell cycle distribution and apoptosis
T. Kurita-Ochiai; T. Hashizume; H. Yonezawa; K. Ochiai; M. Yamamoto
FEMS Immunol Med Microbiol., Jun. 2006, Refereed, Not invited - Evaluation of a Rapid-Immunoassay Kit for S. mutans Using Brushing-Plaque Samples from University Students and School Children
水野恭子、後藤田宏也、田口千恵子、小林清吾、橋爪智美、前田隆秀、福島和雄
小児歯科学雑誌, Mar. 2005, Refereed, Not invited - Effect of One-time PMTC Treatment on Mutans Streptococcal Levels in Brushing-plaque and Stimulated-saliva Samples
岡田珠美、橋爪智美、熱田亙、藤田光、杉山道紀、佐藤京子、福島和雄、池見宅司
日本歯科保存学雑誌, Feb. 2005, Refereed, Not invited - Production of a single-chain variable fraction capable of inhibiting the Streptococcus mutans glucosyltransferase in Bacillus brevis : construction of a chimeric shuttle plasmid secreting its gene product(共著)
T. Shiroza; N. Shinozaki-Kuwahara; M. Hayakawa; Y. Shibata; T. Hashizume; K. Fukushima; S. Udaka; Y. Abiko
Biochimica et Biophysica Acta, Apr. 2003, Refereed, Not invited
Books and other publications
- Mucosal vaccines,Innovation for preventing infectious diseases,Second edition
Contributor, Mucosal vaccine for oral disease, Tomoko Kurita-Ochiai; Tomomi Hashizume-Takizawa; Ryoki Kobayashi; Masafumi Yamamoto
Academic press, 2020 - Mucosal vaccinesInnovation for preventing infectious diseasesSecond edition
Others, Mucosal vaccine for oral disease
Academic press, 2019
Lectures, oral presentations, etc.
- Peyer' s patches are required for antigen-specific systemic IgA induction against oral recombinant Salmonella
Tomomi Hashizume-Takizawa; Hedenobu Senpuku
第53回日本免疫学会, Dec. 2024, Not invited - 16S rRNA遺伝子解析で分類困難であったmitisグループ細菌の分類について
齋藤真規; 桒原紀子; 瀧澤智美; 泉福英信
第66回歯科基礎医学会, Nov. 2024, Not invited - Staphylococcus aureus 由来膜小胞の経鼻免疫による抗原特異的IgA抗体応答の誘導についての検討
瀧澤智美; 齋藤真規; 泉福英信
第66回歯科基礎医学会, Nov. 2024, Not invited - Comparative analysis of Leptotrichia sp. isolated from human oral cavity
Noriko Shinozaki-Kuwahara; Masanori Saito; Tomomi Hashizume-Takizawa; Hidenobu senpuku; Koichi Hiratsuka
第97回日本細菌学会, Aug. 2024 - Nasal Staphylococcus aureus membrane vesicles induces mucosal IgA responses without adjuvant
Tomomi Hashizume-Takizawa; Masanori Saito; Noriko Shinozaki-Kuwahara; Ryoki Kobayashi; Hidenobu Senpuku
第97回日本細菌学会, Aug. 2024 - Novel Streptococcus species forming extremely long chains isolated from the human oral cavity
Masanori Saito, Noriko Shinozaki-Kuwahara, Tomomi Hashizume-Takizawa, Hidenobu Senpuku
第97回日本細菌学会, Aug. 2024 - 経鼻ワクチンによる口腔バイオフィルム形成阻害効果
瀧澤 智美, 泉福 英信
第38回日本バイオフィルム学会, Jul. 2024, Invited - Nasal immunization with Streptococcus mutans membrane vesicles and nano-size hydroxyapatite induced mucosal IgA Ab responses
Hashizume-Takizawa, T; Mochizuki, C; Sakai, Y; Nakamura, K; Senpuku, H
第52回日本免疫学会, Jan. 2024, Not invited - IL-22 regulates salivary β-defensin 3 production after lactic acid bacteria administration
Kobayashi, R; Hashizume-Takizawa, T; Senpuku, H
第52回日本免疫学会, Jan. 2024, Not invited - Analysis of red pigment produced by Arachnia rubra strain SK-1T
Saito, M; Kuwahara, N; Takizawa, T; Kobayashi, R; Senpuku, H
第65回歯科基礎医学会学術大会, Sep. 2023, Not invited - Whole genome analysis of gram-negative filamentous bacilli isolated from saliva
Shinozaki-Kuwahara, N; Saito, M; Hiratsuka, K; Tanaka, Y; Taguchi, C; Hashizume-Takizawa, T; Kobayashi, R; Senpuku, H
第65回歯科基礎医学会学術大会, Sep. 2023, Not invited - Streptococcus sanguinis膜小胞が血管内皮細胞に及ぼす影響
瀧澤智美; 小林良喜; 桒原紀子; 齋藤真規; 泉福英信
第65回歯科基礎医学会学術大会, Sep. 2023, Not invited - Systemic administration of lipopolysaccharide derived from Escherichia coli, but not from Porphyromonas gingivalis, increases blood IL-6, TNF-alpha and IL-10 levels in mice.
Saito, K; Aono, Y; Watanabe, A; Kono, T; Hashizume-Takizawa, T; Okada, H; Senpuku, H; Saigusa, T
第65回歯科基礎医学会学術大会, Sep. 2023, Not invited - 尾静脈投与したStreptococcus mutansのラムノースーグルコース多糖類合成能がマウスの臓器へ及ぼす影響
安藤大貴; 瀧澤智美; 青木和広; 泉福英信
第65回歯科基礎医学会学術大会, Sep. 2023, Not invited - 接着性または非接着性タンパク質固定化バイオアクティブフィルムの開発
布施恵; 松根健介; 中西健人; 岡部達; 瀧澤(橋爪)智美; 田口千恵子; 藤田(中島)光; 桑田(楠瀬)隆生; 卯田昭夫; 岡田裕之; 小倉昭弘
第31回硬組織再生生物学会, Sep. 2023 - 口腔環境の変化に応答する Porphyromonas gingivalis の発現遺伝子の検索
桑原 紀子,平塚 浩一,齋藤 真規,瀧澤 智美,小林 良喜,泉福 英信
第96日本細菌学会, Mar. 2023 - オゾンナノバブル水が口腔細菌叢へおよぼす影響
齋藤真規; 桒原紀子; 瀧澤智美; 泉福英信
第96回日本細菌学会, Mar. 2023, Not invited - Aggregatibacter actinomycetemcomitansの酸性環境での発現遺伝子の動態
桑原 紀子,平塚 浩一,齋藤 真規,田中 陽子,瀧澤 智美,小林 良喜,泉福 英信
第64回歯科基礎医学会, Sep. 2022 - マウスガードを用いた誤嚥性肺炎予防のための口腔ケアシステムの開発
齋藤 真規,岩田 好弘,桑原 紀子,瀧澤 智美,小林 良喜,泉福 英信
第64回歯科基礎医学会, Sep. 2022, Not invited - Effect of eggshell-derived hydroxyapatites on enhancement of mucosal immunity
Tomomi Hashizume-Takizawa; Chihiro Mochizuki; Masanori Saito; Noriko Shinozaki-Kuwahara; Ruoki Kobayashi; Hidenobu Senpuku
第64回歯科基礎医学会学術大会, Sep. 2022, Not invited - Eggshell-derived hydroxyapatite enhance mucosal immunity to Streptococcus mutans vesicles
Tomomi Hashizume-Takizawa; Chihiro Mochizuki; Yuki Sakai; Koichi Nakamura; Hidenobu Senpuku
2022 IADR/APR General Session & Exhibition, Jun. 2022, Not invited - De novo assembly of Actinomyces capricornis strain MAS-1T complete genome sequence
齋藤真規; 桒原紀子; 瀧澤智美; 泉福英信
第95回日本細菌学会総会, Mar. 2022, Not invited - 歯肉溝内のpH変化に関する歯周病原細菌Aggregatibacter actinomycetemcomitans遺伝子発現の検討
桒原紀子; 平塚浩一; 齋藤真規; 瀧澤智美; 泉福英信
第95回日本細菌学会総会, Mar. 2022, Not invited - 細菌由来メンブレンベジクルを用いた粘膜ワクチンにおける卵殻由来水酸アパタイトのアジュバント効果
瀧澤智美; 齋藤真規; 桒原紀子; 泉福英信
第95回日本細菌学会総会, Mar. 2022, Not invited - Inflammatory mediators are increased in vascular endothelial cells in response to Streptococcus sanguinis
Tomomi Hashizume-Takizawa; Tomoko Kurita-Ochiai; Hidenobu Senpuku
第50回日本免疫学会, Dec. 2021, Not invited - 歯周炎モデルマウスによる免疫応答の検討
小林良喜; 瀧澤智美; 泉福英信
第64回秋季日本歯周病学会学術大会, Oct. 2021, Not invited - Streptococcus sanguinisが血管内皮機能に及ぼす影響
瀧澤智美; 桒原紀子; 齋藤真規; 小林良喜; 泉福英信
第63回歯科基礎医学会学術大会, Oct. 2021, Not invited - Arachnia rubra SK-1株のde novo全ゲノムアセンブリ
齋藤真規; 桒原紀子; 瀧澤智美; 小林良喜; 泉福英信
第63回歯科基礎医学会学術大会, Oct. 2021, Not invited - 歯周病関連疾患の解明を目的とした歯周病モデルマウスの確立
小林良喜; 瀧澤智美; 齋藤真規; 桒原紀子; 泉福英信
第63回歯科基礎医学会学術大会, Oct. 2021, Not invited - Streptococcus sanguinis induces vascular inflammation and accelerates atherosclerotic plaque formation
T. Hashizume-Takizawa; N. Shinozaki-Kuwahara; R. Kobayashi; M. Saito; T. Kurita-Ochiai
World microbe forum, Jun. 2021, Not invited - Streptococcus sobrinus誘発性う蝕の抑制におけるIgA抗体の役割
瀧澤智美; 齋藤真規; 桒原紀子; 小林良喜; 落合智子
第94回日本細菌学会総会, Mar. 2021, Not invited - 健常学生の唾液由来におけるStreptococcus sobrinusの分布状況
桒原紀子,齋藤真規,瀧澤智美,小林良喜,落合智子
第62回歯科基礎医学会学術大会, Sep. 2020, Not invited - 羅漢果抽出液の口腔微生物に対する抗菌効果の基礎的研究
齋藤真規,桒原紀子,瀧澤智美,落合智子
第62回歯科基礎医学会学術大会, Sep. 2020, Not invited - 腸管を起点とした口腔免疫機能を活性化させる液性因子の検索
小林良喜,瀧澤智美,落合智子
第62回歯科基礎医学会学術大会, Sep. 2020, Not invited - Oral infection with Streptococcus sanguinis accelerates atherosclerosis in hyperlipidemic mice
Tomomi Hashizume-Takizawa; Yohei Yamaguchi; Ryoki Kobayashi; Noriko Shinozaki-Kuwahara; Masanori Saito; Tomoko Kurita-Ochiai
第93回 日本細菌学会総会, Feb. 2020, Not invited - 健常学生の鼻腔におけるStaphylococcus aureusの保有状況
桑原紀子; 齋藤真規; 瀧澤智美; 小林良喜; 落合智子
第61回歯科基礎医学会, Oct. 2019, Not invited - Probiotic bacterium, Lactobacillus gasseri O3-2 prevent periodontitis via intestinal tract
Ryoki Kobayashi; Tomoko Kurita-OChiai; Tomomi Hashizume-Takizawa
97th General Session & Exhibition of the IADR, Jun. 2019, Not invited - Preventive effect on periodontitis via intestinal tract by Lactobacillus gasseri O3-2
Kobayashi R.; Hahisumze-Takizawa T.; Kurita-Ochiai T.
第60回歯科基礎医学会学術大会, Sep. 2018, Not invited - Medium for cultivation of periodontopathogenic black-pigmented Gram-negative anaerobes
Saito M.; Kuwahara N.; Takizawa T.; Ochiai T.
第60回歯科基礎医学会学術大会, Sep. 2018, Not invited - Identification of novel species of genus Leptotrichia isolated from humen saliva
Kuwahara N.; Saito M.; Takizawa T.; Kobayashi R.; Ochiai T.
第60回歯科基礎医学会学術大会, Sep. 2018, Not invited - The effect of Streptococcus sanguinis and Streptococcus anginosus infection on development of atherosclerosis
Hashizume-Takizawa T.; Kobayashi R.; Shinozaki-Kuwahara N.; Saito M.; Tsuzukibashi O.; Kurita-Ochiai T.
第60回歯科基礎医学会学術大会, Sep. 2018, Not invited - 口腔常在細菌が全身疾患である動脈硬化症に与える影響についての検討
瀧澤智美、小林良喜、桒原紀子、齋藤真規、續橋治、福本雅彦、落合智子
第18回日本大学口腔科学会学術大会, Sep. 2018, Not invited - 脂質代謝異常が歯槽骨吸収に与える影響
小林良喜、瀧澤智美、有川量祟、田口千恵子、後藤田宏也、落合智子
第18回日本大学口腔科学会学術大会, Sep. 2018, Not invited - ロジンを含有した歯のコーティング剤による歯周病原細菌に対する抗菌効果の調査
續橋治; 瀧澤智美,和田幸子,浦井薫子,落合智子
日本歯周病学会60周年記念京都大会, Dec. 2017, Not invited - Surface IgA+ Peyer's patch B cells play key roles for induction of recombinant Salmonella-derived antigen-specific intestinal IgA antibody responses
T.Hashizume-Takizawa
第46回日本免疫学会, Dec. 2017, Not invited - 口臭簡易キットの開発と口臭に関わる細菌の検索
續橋治,内堀聡史,齋藤真規,小林良喜,瀧澤智美,桑原紀子,落合智子
第59回歯科基礎医学会学術大会, Sep. 2017, Not invited - Poly-L-lysine dendrigraft 固定化顎骨再生PLAフィルムの開発
布施恵,深津晶,小倉由希; 小西賀美,小峯千明,渕上真奈; 瀧澤智美; 落合智子; 福本雅彦
第17回日大口腔科学学会, Sep. 2017, Not invited - 口臭に関わる細菌の検索と口臭簡易検出キットの臨床応用
続橋治; 齋藤真規,桒原紀子,小林良喜,瀧澤智美,落合智子
第17回日大口腔科学学会, Sep. 2017, Not invited - Peyer's patch B cells play distinct roles for induction of antigen-specific intestinal IgA antibody responses against orally administered recombinant Salmonella
T.Hashizume-Takizawa; K.Fujihashi; JR.McGhee; Y.Kurashima; N.Shibata; H.Kiyono; T.Kurita-Ochiai
18th International Congress of Mucosal Immunology, Jul. 2017, Not invited - Lactic acid bacteria perevent both periodontitis and atherosclerosis
R. Kobayashi; T. Hashizume; M. Saito; O. Tsuzukibashi; N. Kuwahara; T. Ochiai
第90回日本細菌学会, Mar. 2017, Not invited - フィブロネクチン, アルブミン固定化ポリ（乳酸-ε-カプロラクトン）共重合体フィルムへのマウス骨芽細胞様細胞の付着, 増殖について
布施恵; 深津晶,小倉由希,小西賀美,田中宏征,小峯千明,渕上真奈,瀧澤智美; 落合智子; 福本雅彦
第9回日本口腔検査学会総会, Oct. 2016, Not invited - タンパク固定化ポリ(乳酸-ε-カプロラクトン)共重合体フィルムへのマウス骨芽細胞様細胞の付着・増殖に対するフィブロネクチン,アルブミン固定化の効果
布施恵; 深津晶,小倉由希,小西賀美,田中宏征,小峯千明,渕上真奈,瀧澤智美; 落合智子,福本雅彦
第16回日大口腔科学学会, Sep. 2016, Not invited - 抗Heat Shock Protein（HSP)60特異抗体誘導舌下ワクチンによる歯周病の軽減効果
小林良喜,瀧澤智美; 大口純人,Bhawal Ujjal,細野明,細川典子,落合智子
第16回日大口腔科学学会, Sep. 2016, Not invited - Streptococcus ferus cariogenic factor遺伝子の検索
桑原紀子,斎藤真規,続橋治,小林良喜,瀧澤智美,落合智子
第58回歯科基礎医学会, Aug. 2016, Not invited - Actinomyces israeliiの分離用選択培地の開発とその口腔内分布
続橋治,内堀聡史; 斎藤真規,小林良喜,瀧澤智美,桑原紀子,落合智子
第58回歯科基礎医学会, Aug. 2016, Not invited - ヒト歯肉溝から分離された赤色集落を呈する真菌種Propionibacterium gingivaerubrumの解析
斎藤真規,桑原紀子; 続橋治,瀧澤智美; 小林良喜,落合智子
第58回歯科基礎医学会, Aug. 2016, Not invited - ジンジパインと酸化LDLとのエピトープ交差反応性
落合智子,瀧澤智美,小林良喜
第59回春季日本歯周病学会学術大会, May 2016, Not invited - Porphyromonas gingivalisで憎悪する動脈硬化および歯周病におけるNLRP3インフラマゾームの活性化
落合智子、小林良喜、瀧澤智美、桑原紀子、続橋治、齋藤真規
第57回歯科基礎医学会, Sep. 2015, Not invited - A. actinomycetemcomitans簡易検出キットの開発と臨床応用
続橋治、桑原紀子、齋藤真規、瀧澤智美、小林良喜、落合智子
第57回歯科基礎医学会, Sep. 2015, Not invited - 歯周ポケットから分離された赤色色素産生性新規Propionibacterium属菌の解析
齋藤真規、桑原紀子、続橋治、小林良喜、瀧澤智美、落合智子
第57回歯科基礎医学会, Sep. 2015, Not invited - Aggregatibacter actinomycetemcomitans血清型gのゲノム解析
桒原紀子、齋藤真規、続橋治、瀧澤智美、小林良喜、落合智子
第57回歯科基礎医学会, Sep. 2015, Not invited - Activation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated atherosclerosis and periodontal disease
Y. yamaguchi; R. Kobayashi; T. Hashizume-Takizawa; T. Ando; T. Kurita-Ochiai
93rd IADR, Mar. 2015, Not invited - Activation of NLRP3 inflammasome in Porphyromonas gingivalis-accelerrated atherosclerosis and periodontal disease
Y. Yamaguchi; T. Ochiai; R. Kobayashi; T. Hashizume; T. Ando
第43回日本免疫学会, Dec. 2014, Not invited - 歯周病原性細菌Aggregatibacter actinomycetemcomitans GFP発現株の作成
瀧澤智美、桑原紀子、落合智子
第56回歯科基礎医学会, Sep. 2014, Not invited - LDL酸化変性におけるArg-及びLys-gingipainの役割
落合智子、瀧澤智美、小林良喜
第56回歯科基礎医学会, Sep. 2014, Not invited - Association of inflammasome in periodontal desease and atherosclerosis induced by Porphyromonas gingivalis oral infection
Y. Yamagichi; T. Ochiai; T. Hashizume; R. Kobayashi; T. Ando
American Association of Oral and Maxillofacial Surgeons 96th Annual Meeting, Sep. 2014, Not invited - Inflamed gingiva derived CD11c+ dendritic cell induced Foxp3+ Treg cell
R. Kobayashi; T. Ochiai; T. Hashizume; K. Fujihashi; M. Yamamoto
第42回日本免疫学会学術集会, Dec. 2013, Not invited - Peyer's patch lymphocytes are distinctive in the induction of antigen-specific intestinal mucosal IgA antibody responses against recombinant Salmonella
T. Hashizume-Takizawa; T. Ochiai; M. Yamamoto
第42回日本免疫学会学術集会, Dec. 2013, Not invited - Sublingual immunization with GroEL induces antigen-specific regulatory T cells and reduces bacteria-induced atherosclerosis
M. Hagiwara; T. Kurita-Ochiai; R. Kobayashi; T. Hashizume-Takizawa; M. Yamamoto
第42回日本免疫学会学術集会, Dec. 2013, Not invited - Porphyromonas gingivalis 口腔感染により進展する動脈硬化におけるインフラマソームの関与
山口陽平、落合智子、小林良喜、瀧澤智美、安藤智博
第56回秋季歯周病学会, Sep. 2013, Not invited - Lymphocytes activated in the Peyer's patches, but not in other lymphoid tissues, are essential for intestinal IgA responses against recombinant Salmonella
T. Hashizume-Takizawa; T. Ochiai; M. Yamamoto
16th International Congress of Mucosal Immunology, Jul. 2013, Not invited - Sublingual immunization with GroEL attenuates Porphyromonas gingivalis-induced atherosclerosis
M. Hagiwara; T. Hashizume-Takizawa; T. Kurita-Ochiai; M. Yamamoto
第41回日本免疫学会学術集会, Dec. 2012, Not invited - Severe periodontal tissue damage by Aggregatibacter actinomycetemcominats in mouse model
R. Kobayashi; T. Ochiai; T. Hashizume; K. Fujihashi; M. Yamamoto
第41回日本免疫学会学術集会, Dec. 2012, Not invited - Oxidative modification of lipoprotein by periodontopathic bacteria
T. Kurita-Ochiai; R. Jia; T. Hashizume; M. Yamamoto
European congress of immunology, Sep. 2012, Not invited - 歯周科治療による動脈硬化の進展への効果
吉野祥一、大口純人、落合智子、橋爪智美、目澤優、高井英樹、鈴木桃子、小山朱美、大橋顕二郎、岡野千春、中尾寿美、井上文央、坂巻達夫、小方頼昌
第12回日大口腔科学会, Sep. 2012, Not invited - Midazolam inhibits production of surface IgE antibody of B cells
H. Kusama; R. Kobayashi; T. Hashizume-Takizawa; S. Yuzawa; T. Kurita-Ochiai; M. Yamamoto; K. Shibutani
90th General Seestion & Exhibition of the IADR, Jun. 2012, Not invited - Induction of Foxp3+CD4+ Treg cell by inflammatory-induced gingival dendritic cells
R. Kobayashi; S. Yuzawa; T. Hashizume-Takizawa; T. Kurita-Ochiai; M. Yamamoto
90th General Seestion & Exhibition of the IADR, Jun. 2012, Not invited - Epigallocatechin-3-gallate reduces atherosclerosis exacerbated by Porphyromonas gingivalis
Y. Cai; T; Hashiaume; T. Kurita-Ochiai; M. Yamamoto
90th General Seestion & Exhibition of the IADR, Jun. 2012, Not invited - Association of serum antibodies to Porphyromonas gingivalis HSP60 and atherosclerosis
M. Hagiwara; T. Hashizume-Takizawa; T. Kurita-Ochiai; M. Suemitsu; K. Kutama; H. Yamamoto; Y. Akimoto; M. Yamamoto
90th General Seestion & Exhibition of the IADR, Jun. 2012, Not invited - Emerging function of Th17 responses for development of atherosclerosis infected by Porphyromonas gingivalis
Y. Cai; T. Hashizume; R. Kobayashi; T. Ochiai; M. Yamamoto
日本歯周病学会学術大会, May 2012, Not invited - Porphyromonas gingivalisによる低比重リポタンパクの酸化変性
T. Kurita-Ochiai; T. Hashizume; M. Yamamoto
第40回日本免疫学会学術集会, Nov. 2011, Not invited - Porphyromonas gingivalis由来のheat-shock protein 特異的免疫応答による動脈硬化の誘導
萩原美緒、橋爪智美、落合智子、秋元芳明、山本正文
第53回 歯科基礎医学会学術大会ならびに総会, Oct. 2011, Not invited - Porphyromonas gingivalisのhemagglutinin A抗原領域とマルトース結合タンパクの複合タンパク質の舌下免疫による抗原特異的抗体応答誘導
湯沢仁、橋爪智美、落合智子、安孫子宜光、山本正文
第54回 秋季日本歯周病学会学術大会, Sep. 2011, Not invited - Porphyromonas gingivalis感染による動脈硬化マウスモデルの検討
深澤飛鳥、橋爪智美、落合智子、秋元芳明、山本正文
第54回 秋季日本歯周病学会, Sep. 2011, Not invited - Green tea epigallocatechin-3-gallate reduces atherosclerosis exacerbated by P.gingivalis
Y. Cai; T. Hashizume; T. Kurita-Ochiai; M. Yamamoto
第54回 秋季日本歯周病学会, Sep. 2011, Not invited - Aggregatibacter Actinomycetemcomitans infection Accelerates Atherosclerosis through LDL Oxidation
89th General Seestion & Exhibition of the IADR, Mar. 2011, Not invited - Aggregatibacter Actinomycetemcomitans-Sensitized Monocytes Induce Endothelial Cell Apoptosis
89th Gerenal Session & exhibition of the IADR, Mar. 2011, Not invited - Porphyromonas gingivalis Infection Enhances Th17 Responses for Development of Atherosclerosis
89th Gerebnal Session & Exhibition of the IADR, Mar. 2011, Not invited - Porphyromonas gingivalis Enhances Monocytes Adhesion to Endothelial Cells
T. Hashizume; T. Kurita-Ochiai; M. Yamamoto
89th Gerenal Session & Exhibition of the IADR, Mar. 2011, Not invited - Increased atherosclerotic lesions and Th17 in mice infected with Porphyromonas gingivalis
第52回歯科基礎医学会, Sep. 2010, Not invited - Streptococus sobrinus の菌体外酵素GTF-Iの経鼻免疫によるう蝕ワクチンの検討
第52回歯科基礎医学会, Sep. 2010, Not invited - Porphyromonas gingivalis 感染に動脈硬化マウスモデルの確立
第52回歯科基礎医学会, Sep. 2010, Not invited - Porphyromonas gingivalis による血管内皮細胞及び単球におけるケモカインの発現解析
第52回歯科基礎医学会, Sep. 2010, Not invited - Aggregatibacter actinomycetemcomitans accelerates atherosclerosis with oxidization of low-density lipoprotein
第52回歯科基礎医学会, Sep. 2010, Not invited - Nasal vaccination with a fusion protein of hemagglutinin A antigenic region and maltose-binding protein induces immunity via toll-like receptor 4
第52回歯科基礎医学会, Sep. 2010, Not invited - Antigen priming for mucosal IgA responses occurs solely in Peyer's patch after oral administration of recombinant Salmonella
14th internatinal congress of immunology, Aug. 2010, Not invited - Nasal vaccination with a fusion protein of hemagglutinin A and maltose-binding protein elicits protective immunity against Porphyromonas gingivalis infection
14th international congress of immunology, Aug. 2010, Not invited - Nasal Vaccination With Glucosyltransferase-I And CpG Oligodeoxynucleotides Elicits Antibody Responses
88th General Session & Exhibition of the IADR, Jul. 2010, Not invited - Establishment of P. gingivalis-accelerated atherosclerosis model using normal mice
88th General Session & Exhibition of the IADR, Jul. 2010, Not invited - Porphyromonas gingivalis induces ER stress-induced apoptosis and autophagy in HUVEC
88th General Session & Exhibition of the IADR, Jul. 2010, Not invited - Induction of apoptosis and autophagy in periodontal pathogen sensitized vascular endothelial cells
2nd European Congress of Immunology, Sep. 2009, Not invited - Porphyromonas gingivalisのhemagglutinin A とマルトース結合タンパク複合タンパク質の舌下免疫による口腔への抗体応答誘導
第51回歯科基礎医学会学術大会ならびに総会, Sep. 2009, Not invited - Streptcoccus sobrinusの菌体外酵素GTF-Iの経鼻免疫によるう蝕ワクチンの検討
第51回歯科基礎医学会学術大会ならびに総会, Sep. 2009, Not invited - Porphyromonas gingivalis感染が血管内皮細胞／単球系細胞共培養に及ぼす影響
第51回歯科基礎医学会学術大会ならびに総会, Sep. 2009, Not invited - Oral immunization with outer membrane protein of Porphyromonas gingivalis and CpG oligodeoxynucleotides decreases P. gingivalis-induced atheromatous lesions
第51回歯科基礎医学会学術大会ならびに総会, Sep. 2009, Not invited - Nasal vaccination with a fusion protein of hemagglutinin A and maltose-binding protein elicits CD11c+ CD8alpha+ dendritic cells for mucosal immunity
第51回歯科基礎医学会学術大会ならびに総会, Sep. 2009, Not invited - Intravenous Infection With Actinobacillus actinomycetemcomitans Accelerates Early Atherosclerosis in Apolipoprotein E deficient Mice
第51回歯科基礎医学会学術大会ならびに総会, Sep. 2009, Not invited - CD11b+alphaL+Dendritic Cells Play Crucial Roles in the Induction of Antigen-Specific Mucosal IgA Antibody Responses against Recombinant Salmonella
14th International Congress of Mucosal Immunology, Jul. 2009, Not invited - Nasal Vaccination Induces Long-term Protective Immunity against Porphyromonas gingivalis Infection（共同）
87th General Session & Exhibition of the IADR, Apr. 2009, Not invited - Nasal vaccination with the 40-kDa outer membrane protein of Porphyromonas gingivalis and a nontoxic chimeric enterotoxin adjuvant induces long-term protective immunity with reduced levels of IgE(共同)
第38回日本免疫学会総会･学術集会, Dec. 2008, Not invited - CpG oligodeoxynucleotides as adjuvant for the development of oral vaccine against Porphyromonas gingivalis infection(共同)
第38回日本免疫学会総会･学術集会, Dec. 2008, Not invited - Protective immunity to Porphyromonas gingivalis induced by nasal immunization with a fusion protein of hemegglutinin A and maltose-binding protein(共同)
第38回日本免疫学会総会･学術集会, Dec. 2008, Not invited - Critical role of Peyer's patch CD11b+ dendritic cells for the induction of antigen-specific mucosal IgA antibody responses to recombinant Salmonella
第38回日本免疫学会総会･学術集会, Dec. 2008, Not invited - Sublingual vaccination with outer membrane protein of Porphyromonas gingivalis plus Flt-3 ligand induces antibody responses in mucosal and systemic compartments(共同)
第38回日本免疫学会総会･学術集会, Dec. 2008, Not invited - P.gingivalis外膜タンパク抗原の経皮免疫による防御免疫応答の誘導(共同）
第12回日本ワクチン学会学術集会, Nov. 2008, Not invited - 無毒化キメラ分子アジュバントとP. gingivalis外膜タンパクの経鼻ワクチンによる免疫応答の誘導(共同)
The 50th Annual Meeting of Japanese Association for Oral Biology, Sep. 2008, Not invited - 歯周病原細菌タンパク抗原を発現した乳酸菌による特異的抗体応答の誘導(共同)
The 50th Annual Meeting of Japanese Association for Oral Biology, Sep. 2008, Not invited - P. gingivalis外膜タンパク抗原の経皮免疫による抗原特異的抗体応答の誘導(共同)
The 50th Annual Meeting of Japanese Association for Oral Biology, Sep. 2008, Not invited - The efficacy of CpG oligodeoxynucleotides as an adjuvant for the development of oral vaccine against Porphromonas gingivalis infection.(共同)
The 50th Annual Meeting of Japanese Association for Oral Biology, Sep. 2008, Not invited - Protective immunity to P. gingivalis induced by nasal immunization with a fusion protein of hemagglutinin A and maltose-binding protein(共同)
The 50th Annual Meeting of Japanese Association for Oral Biology, Sep. 2008, Not invited - Intravenous Infection with Oral Pathogens Accelerates Early Atherosclerosis in Apolipoprotein E deficient Mice(共同)
The 50th Annual Meeting of Japanese Association for Oral Biology, Sep. 2008, Not invited - CpG Oligodeoxynucleotide Adjuvant for Mucosal Immunity to Porphromonas gingivalis.（共同）
86th General Session of International Association for Dental Research, Jul. 2008, Not invited - Sublingual Vaccination with Outer Membrane Protein of Porphyromonas gingivalis.(共同）
86th General Session of International Association for Dental Research, Jul. 2008, Not invited - Recombinant modified vaccinia virus Ankara(MVA) expressing multivalent tuberculosis antigens along with IL-15 induces specific IFN-gamma responses in the lung following nasal immunization.(共同）
第11回日本ワクチン学会学術集会, Dec. 2007, Not invited - 歯周病細菌タンパク抗原を発現する乳酸菌による特異的抗体応答の誘導(共同)
第11回日本ワクチン学会学術集会, Dec. 2007, Not invited - Lymphostructure of Peyer's patch is important for induction of intestinal IgA immunity against recombinant Salmonella
第37回日本免疫学会総会･学術集会, Nov. 2007, Not invited - CpG oligodeoxynucleotides is an effective oral adjuvant for the induction of mucosal immunity against 40-kDa outer membrane protein of Porphyromonas gingivalis（共同）
第37回日本免疫学会総会･学術集会, Nov. 2007, Not invited - Nasal immunization with outer membrane protein of Porphyromonas gingivalis plus nontoxic chimeric enterotoxin adjuvant elicite protective immunity against P. gingivalis infection（共同）
13 th International Congress of Immunology, Aug. 2007, Not invited - A role of reactive oxygen species in nitochondria-, TNF-, and endoplasmic reticulum stress-mediated apoptosis induced by butyric acid（共同）
13th international Congress of Immunology, Aug. 2007, Not invited - Importance of organized Peyer's patches for IgA immunity against Salmonella-derived antigen
13th International Congress of Immunology, Aug. 2007, Not invited - Peyer's patches are required for induction of intestinal IgA responses against Salmonella-derived antigen
13th International Congress of Mucosal Immunology, Jul. 2007, Not invited - A nontoxic chimeric enterotoxin adjuvant for oral immunity to outer membrane protein of Porphromonas gingivalis（共同）
13th International Congress of Mucosal Immunology, Jul. 2007, Not invited - Lack of intestinal IgA responses in Peyer's patch-null mice against Salmonella-derived antigen
橋爪智美/劉晨路; 山本正文
第36回日本免疫学会総会･学術集会, Dec. 2006, Not invited - A nontoxic adjuvant for oral immunity to outer membrane protein of Porphromonas gingivalis (共同）
第36回日本免疫学会総会･学術集会, Dec. 2006, Not invited - Lack of mucosal and systemic IgA responses in Peyer's patch-null mice following oral immunization with recombinant Salmonella
American Association of Immunologists, May 2006, Not invited - GALT Compensatory Network for the Induction of Antigen-specific IgG but not IgA Responses against Salmonella-derived Antigen
第35回日本免疫学会総会･学術集会, Dec. 2005, Not invited - Role of reactive oxygen species in bacterial infection（共同）
第35回日本免疫学会総会･学術集会, Dec. 2005, Not invited - 高う蝕者と無う蝕者のGTF-B産生性について
第47回歯科基礎医学会学術大会ならびに総会, Sep. 2005, Not invited - Role of reactive oxygen species in butyric acid-induced T cell apoptosis
7th World Congress on Inflammation, Sep. 2005, Not invited - 歯周病原性細菌の産生するヒトIL-1β様物質の精製と分子生物学的解析
第78回日本細菌学会総会, Apr. 2005, Not invited - 歯垢中のS.sobrinus GTF-Iを直接定量できるサンドイッチELISA系の構築
第46回歯科基礎医学会, Sep. 2004, Not invited - S.mutansGTF-Bの局在性および総生産量についての解析
第46回歯科基礎医学会学術大会ならびに総会, Sep. 2004, Not invited - サンドイッチELISA系を用いた歯垢･唾液中のGTF-B量の定量とS.mutans 菌数レベル及びDMFTとの相関について
第45回歯科基礎医学会, Sep. 2003, Not invited - バイオフィルム形成及び非形成過程におけるS.mutansGTF-Bの産生性と局在性
第45回歯科基礎医学会学術集会及び総会, Sep. 2003, Not invited - サンドイッチELISA法によるS.mutans株のGTF-B産生性の解析
第44回歯科基礎医学会学術大会ならびに総会, Oct. 2002, Not invited - 変性米糠アラビノキシラン由来の培養系癌細胞増殖抑制成分に関する研究
日本農芸化学会2002年度大会, Mar. 2002, Not invited - ヒト胎盤水解物におけるHL60細胞増殖抑制成分の検索
日本農芸化学会2000年度大会, Apr. 2000, Not invited
Research Themes
- メンブレンベジクルを利用した多機能性ワクチンプラットフォームの開発
日本学術振興会, 科学研究費助成事業, Apr. 2022 - Mar. 2025
瀧澤 智美; 泉福 英信 - 経口ワクチン接種時のパイエル板における粘膜免疫誘導機序の解明
Apr. 2015 - Mar. 2018 - 歯周病起因性動脈硬化における歯周病原性細菌の動態及び制御機序についての解析
2012 - 2014 - 歯周炎で誘導される動脈硬化の自己免疫疾患様病態の解明と経口免疫寛容による制御
2010 - 2012 - 有効な経口投与型ワクチンを開発するための腸管粘膜免疫応答誘導機序の解明
2010 - 2011 - P.gingivalis 感染予防のための安全・有効な経口，経鼻ワクチンの開発
2007 - 2008
