UKIYA Motohiko
| Department of Materials and Applied Chemistry | Professor |
Researcher Information
Research Keyword
Field Of Study
- Life sciences, Pharmaceuticals - chemistry and drug development, Chemical Pharmaceutical Science
- Life sciences, Pharmaceuticals - chemistry and drug development, Drug Development Chemistry
- Life sciences, Bioorganic chemistry, Organic Chemistry
- Life sciences, Bioorganic chemistry, Biological Production Chemistry/Biological Organic Chemistry
Research activity information
Paper
- Promotion of ABCG2 gene expression by neolignans from Piper longum L.
Atsuyoshi Nishina; Motohiko Ukiya; Kazuki Motegi; Risa Kiryu; Daisuke Sato; Mitsuru Sada; Yuki Hori; Hideo Satsu; Kazuhiro Uemura; Mamoru Koketsu; Masayuki Ninomiya; Lwin Mon Mon Myint; Hirokazu Kimura
Bioscience, Biotechnology, and Biochemistry, Sep. 2023, Refereed - Amino Acid Conjugates of ent-Beyerane-type Diterpenoids and Oleanane-type Triterpenoids : Synthesis and Evaluation of Cytotoxic Activities
Motohiko Ukiya; Tomoyuki Sekine; Naoto Shimizu; Hiroyuki Akazawa; Minoru Tanigawa; Yusuke Suzuki; Atsuyoshi Nishina
JOURNAL OF OLEO SCIENCE, 2023, Refereed
Lead - Rapid removal of detergent in glycolipids using ionic liquids
Shoko Matsushita; Kazuhiko Noda; Shuta Hara; Jumpei Aisu; Aki Hayashi; Hiroki Ikake; Shigeru Shimizu; Minoru Tanigawa; Motohiko Ukiya; Katsushi Nishimura; Atsuyoshi Nishina; Yusuke Suzuki
Analytical Sciences, Jun. 2022, Refereed, Not invited - Effect of Compounds from Moringa oleifera Lam. on in Vitro Non-Alcoholic Fatty Liver Disease (NAFLD),Model System
Ukiya; Motohiko; Motegi; Kazuki; Sato; Daisuke; Kimura; Hirokazu; Satsu; Hideo; Koketsu; Mamoru; Ninomiya; Masayuki; Myint; Lwin Mon; Nishina; Atsuyoshi
Chemistry & Biodiversity, 2021, Refereed, Not invited
Lead - Cardiac glycosides from the roots of Streblus asper Lour. and their apoptosis-inducing activities in,A549 cells
Zhang; Bo-dou; Zhu; Wan-fang; Akihisa; Toshihiro; Kikuchi; Takashi; Ukiya; Motohiko; Maya; Fukuda; Xu; Jian; Liu; Wen-yuan;; Feng; Feng; Zhang; Jie
Phytochemistry, 2021, Refereed - Biological activities of flavonoids from the wood extract of Artocarpus heterophyllus L. (Jackfruit)
Akazawa; Hiroyuki; Shinozaki; Takuro; Ukiya; Motohiko; Akihisa; Toshihiro; Jiradej; Manosroi; Tokuda; Harukuni; Fukatsu; Makoto
Natural Products Journal, 2020, Refereed - Tokoronin Contained in Dioscorea tokoro Makino ex Miyabe Suppressed α-MSH-Induced,Melanogenesis in B16 Cells via Suppression of Classical MAPK Pathway Activation
Ukiya; Motohiko; Sato; Daisuke; Kimura; Hirokazu; Hirai; Yasuaki; Nishina; Atsuyoshi
Chemistry & Biodiversity, 2020, Refereed
Lead - (-)-O-methylcubebin from Vitex trifolia enhancedadipogenesis in 3T3-L1 cells via the inhibition,ofERK1/2 and p38MAPK phosphorylation
Ukiya; Motohiko; Sato; Daisuke; Kimura; Hirokazu; Koketsu; Mamoru; Phay; Nyunt; Nishina; Atsuyoshi
Molecules, 2020, Refereed
Lead - Synthesis of Lanostane-Type Triterpenoid N-Glycosides and Their Cytotoxicity against Human Cancer Cell Lines
Ukiya; Motohiko Hayakawa; Teppei Okazaki; Kouta Hikawa; Maiko Akazawa; Hiroyuki Li; Wei Koike; Kazuo Fukatsu; Makoto
Chemistry & Biodiversity, 2018, Refereed, Not invited
Lead - Cytotoxic and Apoptosis-inducing Activities of Taraxastane-type Triterpenoid Derivatives in Human Cancer Cell Lines
Motohiko Ukiya; Chika Ohkubo; Masahiro Kurita; Makoto Fukatsu; Takashi Suzuki; Toshihiro Akihisa
CHEMISTRY & BIODIVERSITY, Aug. 2016, Refereed, Not invited
Lead - Melanogenesis-Inhibitory Activity and Cancer Chemopreventive Effect of Glucosylcucurbic Acid from Shea (Vitellaria paradoxa) Kernels
Jie Zhang; Masahiro Kurita; Kodai Ebina; Motohiko Ukiya; Harukuni Tokuda; Ken Yasukawa; Eliot T. Masters; Naoto Shimizu; Momoko Akihisa; Feng Feng; Toshihiro Akihisa
CHEMISTRY & BIODIVERSITY, Apr. 2015, Refereed, Not invited - Effects of various 5,7-dihydroxyflavone analogs on adipogenesis in 3T3-L1 cells
Atsuyoshi Nishina; Motohiko Ukiya; Makoto Fukatsu; Mamoru Koketsu; Masayuki Ninomiya; Daisuke Sato; Junpei Yamamoto; Kazuo Kobayashi-Hattori; Takeshi Okubo; Hideyo Tokuoka; Hirokazu Kimura
Biological and Pharmaceutical Bulletin, 2015, Refereed, Not invited - Dioscin Derived from Solanum melongena L. "Usukawamarunasu" Attenuates α-MSH-Induced Melanogenesis in B16 Murine Melanoma Cells via Downregulation of Phospho-CREB and MITF
Atsuyoshi Nishina; Kodai Ebina; Motohiko Ukiya; Makoto Fukatsu; Mamoru Koketsu; Masayuki Ninomiya; Daisuke Sato; Hirokazu Kimura
Journal of Food Science, 2015, Refereed, Not invited - Triterpene glycosides and other polar constituents of shea (Vitellaria paradoxa) kernels and their bioactivities
Jie Zhang; Masahiro Kurita; Takuro Shinozaki; Motohiko Ukiya; Ken Yasukawa; Naoto Shimizu; Harukuni Tokuda; Eliot T. Masters; Momoko Akihisa; Toshihiro Akihisa
PHYTOCHEMISTRY, Dec. 2014, Refereed, Not invited - Three New and Other Limonoids from the Hexane Extract of Melia azedarach Fruits and Their Cytotoxic Activities
Xin Pan; Masahiro Matsumoto; Yasuhiro Nakamura; Takashi Kikuchi; Jie Zhang; Motohiko Ukiya; Takashi Suzuki; Kazuo Koike; Rima Akihisa; Toshihiro Akihisa
CHEMISTRY & BIODIVERSITY, Jul. 2014, Refereed, Not invited - Cytotoxic and Apoptosis-Inducing Activities, and Anti-Tumor-Promoting Effects of Cyanogenated and Oxygenated Triterpenes
Takashi Kikuchi; Kenta Ishii; Eri Ogihara; Jie Zhang; Motohiko Ukiya; Harukuni Tokuda; Takashi Iida; Reiko Tanaka; Toshihiro Akihisa
CHEMISTRY & BIODIVERSITY, Apr. 2014, Refereed, Not invited - Limonoids and Flavonoids from the Flowers of Azadirachta indica var. siamensis, and Their Melanogenesis-Inhibitory and Cytotoxic Activities
Worapong Kitdamrongtham; Kenta Ishii; Kodai Ebina; Jie Zhang; Motohiko Ukiya; Kazuo Koike; Hiroyuki Akazawaa); Aranya Manosroia); Jiradej Manosroi; Toshihiro Akihisa
Chemistry & Biodiversity, 2014, Refereed, Not invited - Limonoids and Flavonoids from the Flowers of Azadirachta indica var. siamensis, and Their Melanogenesis-Inhibitory and Cytotoxic Activities
Worapong Kitdamrongtham; Kenta Ishii; Kodai Ebina; Jie Zhang; Motohiko Ukiya; Kazuo Koike; Hiroyuki Akazawaa; Aranya Manosroia; Jiradej Manosroi; Toshihiro Akihisa
Chemistry & Biodiversity, 2014, Refereed, Not invited - Cytotoxic and Nitric Oxide Production-Inhibitory Activities of Limonoids and Other Compounds from the Leaves and Bark of Melia azedarach
Xin Pan; Masahiro Matsumoto; Yuki Nishimoto; Eri Ogiharaa); Jie Zhang; Motohiko Ukiya; Harukuni Tokuda; Kazuo Koike; Momoko Akihisa; Toshihiro Akihisa
Chemistry & Biodiversty, 2014, Refereed, Not invited - Cytotoxic and Melanogenesis-Inhibitory Activities of Limonoids from the Leaves of Azadirachta indica (Neem)
Mio Takagi; Yosuke Tachi; Jie Zhang; Takuro Shinozaki; Kenta Ishii; Takashi Kikuchi; Motohiko Ukiya; Norihiro Banno; Harukuni Tokuda; Toshihiro Akihisa
Chemistry & Biodiversty, 2014, Refereed, Not invited - Glycosidic Inhibitors of Melanogenesis from Leaves of Passiflora edulis
Jie Zhang; Ryosuke Koike; Ayako Yamamoto; Motohiko Ukiya; Makoto Fukatsu; Norihiro Banno; Motofumi Miura; Shigeyasu Motohashi; Harukuni Tokuda; Toshihiro Akihisa
CHEMISTRY & BIODIVERSITY, Oct. 2013, Refereed, Not invited - Cytotoxic Activities of Amino Acid-Conjugate Derivatives of Abietane-Type Diterpenoids against Human Cancer Cell Lines
Motohiko Ukiya; Takuma Kawaguchi; Kenta Ishii; Eri Ogihara; Yosuke Tachi; Masahiro Kurita; Yoichiro Ezaki; Makoto Fukatsu; Yasunori Kushi; Toshihiro Akihisa
CHEMISTRY & BIODIVERSITY, Jul. 2013, Refereed, Not invited
Lead - Cytotoxic and Apoptosis-Inducing Activities of Steviol and Isosteviol Derivatives against Human Cancer Cell Lines
Sawada; Shingo Kikuchi; Takashi Kushi; Yasunori Fukatsu; Makoto Akihisa; Toshihiro
Chemistry&Biodiversity, Feb. 2013, Refereed, Not invited
Lead - Melanogenesis-inhibitory and cytotoxic activities of diarylheptanoids from Acer nikoense bark and their derivatives
Akihisa; Toshihiro Takeda; Ayano Akazawa; Hiroyuki Kikuchi; Takashi Yokokawa; Satoru Fukatsu; Makoto Watanabe; Kensuke
Chemistry&Biodiversity, Sep. 2012, Refereed, Not invited - Cytotoxic and apoptosis-inducing activities of triterpene acids from Poria cocos.
Kikuchi; T.; Uchiyama; E.; Ukiya; M.; Tabata; K.; Kimura; Y.; Suzuki; T.; Akihisa; T.
J. Nat. Prod., Feb. 2011, Refereed, Not invited - Antitumor-promoting effects and cytotoxic activities of dammar resin triterpenoids and their derivatives.
Ukiya; M.; Kikuchi; T.; Tokuda; H.; Tabata; K.; Kimura; Y.; Arai; T.; Ezaki; Y.; Oseto; O.; Suzuki; T.; Akihisa; T.
Chem. Biodivers., Aug. 2010, Refereed, Not invited
Lead - Oxyfunctionalization of inactivated C-H bonds in triterpenoids with tert-butylhydroperoxide catalyzed by meso-5,10,15,20-tetramesitylporphyrinate osmium(II) carbonyl complex
Ogata; S.; Wakatsuki; Y.; Makino; M.; Fujimoto; Y.; Yasukawa; K.; Kikuchi; T.; Ukiya; M.; AKihisa; T.; Iida; T.
Chem. Phys. Lipids, Feb. 2010, Refereed, Not invited - Cancer chemopreventive effects of cycloartane-type and related triterpenoids in in vitro and in vivo models
Kikuchi; T.; Akihisa; T.; Tokuda; H.; Ukiya; M.; Watanabe; K.; Nishino; H.
J. Nat. Prod., 2007, Not refereed, Not invited - Triterpene glycosides from the flower petals of sunflower (Helianthus annuus) and their anti-inflammatory activity
Motohiko Ukiya; Toshihiro Akihisa; Ken Yasukawa; Kazuo Koike; Akitomo Takahashi; Takashi Suzuki; Yumiko Kimura
J. Nat. Prod., 2007, Refereed, Not invited
Lead - Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects
Akihisa; T.; Higo; N.; Tokuda; H.; Ukiya; M.; Akazawa; H.; Tochigi; Y.; Kimura; Y.; Suzuki; T.; Nishino; H.
J. Nat. Prod., 2007, Not refereed, Not invited - Chalcones and other compounds from the Exudates of Angelica keiskei and Their Cancer Chemopreventive Effects
Toshihiro Akihisa; Harukuni Tokuda; Daisuke Hasegawa; Motohiko Ukiya; Yumiko Kimura; Fumio Enjo; Takashi Suzuki; Hoyoku Nishino
J. Nat. Prod., 2006, Refereed, Not invited - Anti-inflammatory, anti-tumor promoting, and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers
Motohiko Ukiya; Toshihiro Akihisa; Ken Yasukawa; Harukuni Tokuda; Takashi Suzuki; Yumiko Kimura
J. Nat. Prod., 2006, Refereed, Not invited
Lead - Antitubercular activity of triterpenoids from Asteraceae flowers
Toshihiro Akihisa; Scott G. Franzblau; Motohiko Ukiya; Hiroki Okuda; Fangqiu Zhang; Ken Yasukawa; Takashi Suzuki; Yumiko Kimura
Biol. Pharm. Bull., 2005, Refereed, Not invited - Azaphilones, furanoisophthalides, and amino acids from the extracts of Monascus pilosus-fermented rice (Red-mold rice) and their chemopreventive effects
Toshihiro Akihisa; Harukuni Tokuda; Ken Yasukawa; Motohiko Ukiya; Ayaka Kiyota; Naoyuki Sakamoto; Takashi Suzuki; Nobukazu Tanabe; Hoyoku Nishino
J. Agric. Food Chem., 2005, Refereed, Not invited - Oxygenated lanostane-type triterpenoids from the fungus Ganoderma lucidum
Toshihiro Akihisa; Masaaki Tagata; Motohiko Ukiya; Harukuni Tokuda; Takashi Suzuki; Yumiko Kimura
J. Nat. Prod., 2005, Refereed, Not invited - Antitubercular activity and inhibitory effect on Epstein-Barr virus activation of sterols and polyisoprenepolyols from an edible mushroom, Hypsizigus marmoreus
T. Akihisa; S. G. Franzblau; H. Tokuda; M. Tagata; M. Ukiya; T. Matsuzawa; K. Metori; Y. Kimura; T. Suzuki; K. Yasukawa
Biol. Pharm. Bull., 2005, Refereed, Not invited - Cucurbitane-type triterpenoids from the fruit of Momordica charantia
Y. Kimura; T. Akihisa; N. Yuasa; M. Ukiya; T. Suzuki; M. Toriyama; S. Motohashi; H. Tokuda
J. Nat. Prod., 2005, Refereed, Not invited - Xanthoangelol, a major chalcone constituents of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells
K. Tabata; K. Motani; N. Takayanagi; R. Nishimura; S. Asami; Y. Kimura; M. Ukiya; D. Hasegawa; T. Akihisa; T. Suzuki
Biol. Pharm. Bull., 2005, Refereed, Not invited - Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors
Y. Mizushina; T. Akihisa; M. Ukiya; Y. Hamasaki; C. Murakami-Nakai; I. Kuriyama; T. Takeuchi; F. Sugawara; H. Yoshida
Life Sciences, 2005, Refereed, Not invited - Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica
N. Banno; T. Akihisa; H. Tokuda; K. Yasukawa; Y. Taguchi; H. Akazawa; M. Ukiya; Y. Kimura; T. Suzuki; H. Nishino
Biol. Pharm. Bull., 2005, Refereed, Not invited - Anti-tumor-initiating effects of monascin, an azaphilonoid pigment from the extract of Monascus pilosus fermented rice (red-mold rice)
T. Akihisa; H. Tokuda; M. Ukiya; A. Kiyota; K. Yasukawa; N. Sakamoto; Y. Kimura; T. Suzuki; J. Takayasu; H. Nishino
Chem. Biodivers., 2005, Refereed, Not invited - A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos
Yoshiyuki Mizushina; Toshihiro Akihisa; Motohiko Ukiya; Chikako Murakami; Isoko Kuriyama; Xianai Xu; Hiromi Yoshida; Kengo Sakaguchi
Cancer Sci., 2004, Refereed, Not invited - Dehydrotrametenonic acid and dehydroeburiconic acid from Poria cocos and their inhibitory effects on eukaryotic DNA polymerase α and β
Toshihiro Akihisa; Yoshiyuki Mizushina; Motohiko Ukiya; Manabu Oshikubo; Seizo Kondo; Yumiko Kimura; Takashi Suzuki; Takaaki Tai
Biosci. Biotechnol. Biochem., 2004, Refereed, Not invited - (+)- and (-)-syn-2-Isobutyl-4-methylazetidine-2,4-dicarboxylic acid from the extract of monascus pilosus-fermented rice (red-mold rice)
Toshihiro Akihisa; Shoichi Mafune; Motohiko Ukiya; Yumiko Kimura; Ken Yasukawa; Takashi Suzuki; Harukuni Tokuda; Nobukazu Tanabe; Tadahiko Fukuoka
J. Nat. Prod., 2004, Refereed, Not invited - Microbial transformation of isosteviol and inhibitory effects on Epstein-Barr virus activation of the transformation products
Toshihiro Akihisa; Yusuke Hamasaki; Harukuni Tokuda; Motohiko Ukiya; Yumiko Kimura; Hoyoku Nishino
J. Nat. Prod., 2004, Refereed, Not invited - Cancer chemopreventive effects of polyunsaturated fatty acids
Toshihiro Akihisa; Harukuni Tokuda; Masakazu Ogata; Motohiko Ukiya; Masao Iizuka; Takashi Suzuki; Koichi Metori; Naoto Shimizu; Hoyoku Nishino
Cancer Lett., 2004, Refereed, Not invited - Triterpe Acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects
Norihiro Banno; Toshihiro Akihisa; Harukuni Tokuda; Ken Yasukawa; Hiroshi Higashihara; Motohiko Ukiya; Kenji Watanabe; Yumiko Kimura; Jun-ichi Hasegawa; Hoyoku Nishino
Biosci. Biotechnol. Biochem, 2004, Refereed, Not invited - 3-Epicabraleahydroxylactone and other triterpenoids from camellia oil and their inhibitory effects on Epstein-Barr virus activation
Toshihiro Akihisa; Harukuni Tokuda; Motohiko Ukiya; Toshie Suzuki; Fumio Enjo; Kazuo Koike; Tamotsu Nikaido; Hoyoku Nishino
Chem. Pharm. Bull., 2004, Refereed, Not invited - Lucidenic acid P and Q, methyl lucidenate P, and other triterpenoids from the fungus ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation
Kenji Iwatsuki; Toshihiro Akihisa; Harukuni Tokuda; Motohiko Ukiya; Manabu Oshikubo; Yumiko Kimura; Takeshi Asano; Atsushi Nomura; Hoyoku Nishino
J. Nat. Prod., 2003, Refereed, Not invited - Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects
Toshihiro Akihisa; Harukuni Tokuda; Motohiko Ukiya; Masao Iizuka; Stefan Schneider; Kazuya Ogasawara; Teruo Mukainaka; Kenji Iwatsuki; Takashi Suzuki; Hoyoku Nishino
Cancer Lett., 2003, Refereed, Not invited - Sterol Ferulates, Sterols, and 5-alk(en)ylresorcinols from wheat, rye, and corn bran oil and their inhibitory effects on Epstein-Barr virus activation
Kenji Iwatsuki; Toshihiro Akihisa; Harukuni Tokuda; Motohiko Ukiya; Hiroshi Higashihara; Teruo Mukainaka; Masao Iizuka; Yoshiharu Hayashi; Yumiko Kimura; and Hoyoku Nishino
J. Agric. Food Chem., 2003, Refereed, Not invited - Isolation, Structural Elucidation, and Inhibitory Effects of Terpenoid and Lipid Constituents from Sunflower Pollen on Epstein-Barr Virus Early Antigen Induced by Tumor Promoter, TPA
M. Ukiya; T. Akihisa; H. Tokuda; K. Koike; J. Takayasu; H. Okuda; Y. Kimura; T. Nikaido; H. Nishino
J. Agric. Food Chem., 2003, Refereed, Not invited
Lead - Sunpollenol and Five Other Rearranged 3,4-seco-Tirucallane-Type Triterpenoids from Sunflower Pollen and Their Inhibitory Effects on Epstein-Barr Virus Activation
M. Ukiya; T. Akihisa; H. Tokuda; K. Koike; Y. Kimura; T. Asano; S. Motohashi; T. Nikaido; H. Nishino
J. Nat. Prod., 2003, Refereed, Not invited
Lead - Inhibition of Tumor-Promoting Effects by Poricoic Acids G and H and Other Lanostane-type Triterpenes and Cytotoxic Activity of Poricoic A and G from Poria cocos
M. Ukiya; T. Akihisa; H. Tokuda; M. Hirano; M. Oshikubo; Y. Nobukuni; Y. Kimura; T. Tai; S. Kondo; H. Nishino
J. Nat. Prod., 2002, Refereed, Not invited
Lead - Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica
M. Ukiya; T. Akihisa; K. Yasukawa; H. Tokuda; M. Toriumi; K. Koike; Y. Kimura; T. Nikaido; W. Aoi; H. Nishino; M. Takido
J. Nat. Prod., 2002, Refereed, Not invited
Lead - Inhibitory Effects of Cucurbitane Glycosides and Other Triterpenoids from the Fruit of Momordica grosvenori on Epstein-Barr Virus Early Antigen Induced by Tumor Promoter 12-O-Tetradecanoylphorbol-13-Acetate
M. Ukiya; T. Akihisa; H. Tokuda; M. Toriumi; T. Mukainaka; N. Banno; Y. Kimura; J. Hasegawa; H. Nishino
J. Agric. Food Chem., 2002, Refereed, Not invited
Lead - Constituents of Compositae Plants Ⅲ. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene dids and trids from edible chrysanthemum flowers
M. Ukiya; T. Akihisa; H. Tokuda; H. Suzuki; T. Mukainaka; E. Ichiishi; K. Yasukawa; Y. Kasahara; H. Nishino
Cancer Lett., 2002, Refereed, Not invited
Lead - Constituents of Compositae Plants. 2. Triterpene Diols, Triols, and Their 3-0-Fatty Accd Esters from Edible Chrysanthemum Flower Extract and Their Anti-inflammatory Effects
M. Ukiya; T. Akihisa; K. Yasukawa; Y. Kasahara; Y. Kimura; K. Koike; T. Nikaido; M. Takido
J. Agric. Food Chem., 2001, Refereed, Not invited
Lead - 6S,8R-stereochemistry of the C-27- and C-29-alkane-6,8-diols isolated from three Compositae flowers
M Ukiya; T Akihisa; S Motohashi; K Yasukawa; Y Kimura; Y Kasahara; M Takido; N Tokutake
CHEMICAL & PHARMACEUTICAL BULLETIN, Aug. 2000, Refereed, Not invited
Lead - Triterpene alcohol and sterol ferulates from rice bran and their anti-inflammatory effects
T Akihisa; K Yasukawa; M Yamaura; M Ukiya; Y Kimura; N Shimizu; K Arai
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, Jun. 2000, Refereed, Not invited - Acyclic and incompletely cyclized triterpene alcohols in the seed oils of Theaceae and Gramineae
T Akihisa; K Koike; Y Kimura; N Sashida; T Matsumoto; M Ukiya; T Nikaido
LIPIDS, Nov. 1999 - Inhibitory effect of heliantriol C; a component of edible Chrysanthemum, on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin
K Yasukawa; T Akihisa; Y Kasahara; M Ukiya; K Kumaki; T Tamura; S Yamanouchi; M Takido
PHYTOMEDICINE, May 1998, Refereed, Not invited
MISC
- 5,7-Dihydroxyflavone analogues may regulate lipopolysaccharide-induced inflammatory responses by suppressing I kappa B alpha-linked Akt and ERK5 phosphorylation in RAW 264.7 macrophages
A. Nishina; M. Ukiya; M. Fukatsu; M. Koketsu; M. Ninomiya; D. Sato; H. Kimura
PLANTA MEDICA, Dec. 2016, Not refereed, Not invited - (+)- and (-)-syn-2-isobutyl-4-methylazetidine-2,4-dicarboxylic acids from the extract of Monascus pilosus-fermented rice (red-mold rice). (vol 67, pg 479, 2004)
T Akihisa; S Mafune; M Ukiya; Y Kimura; K Yasukawa; T Suzuki; H Tokuda; N Tanabe; T Fukuoka
JOURNAL OF NATURAL PRODUCTS, Sep. 2005, Not refereed, Not invited - Selective inhibition of the activities of both DNA polymerases and DNA topoisomerase II by lanostane-type triterpene acids from Poria cocos
Y.Mizushina; T.Akihisa; M.Ukiya; C.Murakami; I.Kuriyama; X.Xu; H.Yoshida; K.Sakaguchi
Cancer Sci., 2004, Not refereed, Not invited - Microbial transformations of two lupane-type triterpenes and anti-tumor-promoting effects of the transformation products
T Akihisa; Y Takamine; K Yoshizumi; H Tokuda; Y Kimura; M Ukiya; T Nakahara; T Yokochi; E Ichiishi; H Nishino
JOURNAL OF NATURAL PRODUCTS, Mar. 2002, Not refereed, Not invited - Inhibitory Effects of Triterpenoids and Sterols on Human Immunodeficiency Virus-1 Reverse Transcriptase
秋久 俊博; Jun Ogihara; Jun Kato; Ken Yasukawa; Motohiko Ukiya; Sake Yamanouchi; Kunio Oishi
Lipids, 2001, Not refereed, Not invited - Inhibition of Trypsin and Chymotrypsin by Anti-Inflammatory Triterpenoids from Compositae Flowers
秋久 俊博; Antonio Rajic; Motohiko Ukiya; Ken Yasukawa; R. Mark Sanderman; David S. Chandler; Gideon M. Polya
Planta Medica, 2001, Not refereed, Not invited - Anti-Tumor Promoting Effects of Multiflorane-Type Triterpenoids and Cytotoxic Activity of Karounidiol against Human Cancer Cll Lines
秋久 俊博; Harukuni Tokuda; Eiichiro Ichiishi; Teruo Mukainaka; Masakazu Toriumi; Motohiko Ukiya; Ken Yasukawa; Hoyoku Nishino
Cancer Letters, 2001, Not refereed, Not invited - (17α,20R)-Dammara-12,24-dien-3b-ol : A Novel Triterpenoid from Clusia guaviarensis
AKIHISA Toshihiro; OLIVARES Eduardo Martinez; KIMURA Yumiko; UKIYA Motohiko; MONACHE Franco Delle
Journal of Japan Oil Chemical Society, 1999, Not refereed, Not invited
Books and other publications
Lectures, oral presentations, etc.
- ★トリテルペノイドを用いたPROTACsの合成および腫瘍細胞傷害活性
浮谷 基彦、喜佐見 智也、清水 尚登、仁科 淳良
日本薬学会第１４２年会, Mar. 2022 - がん治療薬開発を目指したタンパク質分解分子の合成
喜佐見智也,仁科淳良,浮谷基彦
第65回日本大学理工学部学術講演会, Dec. 2021 - トリテルペノイド由来α－アミノ酸合成および腫瘍細胞傷害活性
関根 兆,浮谷基彦,岡崎航太,仁科淳良,深津 誠
日本薬学会第139年会, Mar. 2019, 日本薬学会, Not invited - ジテルペノイド－アミノ酸結合体の合成および腫瘍細胞傷害活性
関根智之,浮谷基彦,宮地由皓,保科裕子,仁科淳良,深津 誠
日本薬学会第139年会, Mar. 2019, 日本薬学会, Not invited - オレアナン型トリテルペノイド－アミノ酸結合体の合成および腫瘍細胞傷害活性
住吉大輔,浮谷基彦,石井佳菜恵,山﨑貴司,仁科淳良,深津 誠
日本薬学会第139年会, Mar. 2019, 日本薬学会, Not invited - ジテルペノイド由来α-アミノ酸の合成および腫瘍細胞傷害活性評価
岡崎航太,浮谷基彦,仁科淳良,深津 誠,鈴木 孝
日本生薬学会第64回年会, Sep. 2017, Not invited - ジテルペノイド－アミノ酸結合体のアポトーシス誘導効果
保科裕子,浮谷基彦,仁科淳良,深津 誠,鈴木 孝
日本生薬学会第64回年会, Sep. 2017, Not invited - ラノスタン型トリテルペノイドN-配糖体の合成と腫瘍細胞傷害活性
樋川舞子,早川哲平,岡崎航太,仁科淳良,深津 誠,浮谷基彦
平成29年度日本大学理工学部学術講演会, 2017, 日本大学理工学部, Not invited - 副作用低減を目指した天然物アミノ酸誘導体の合成
細野 智史,浮谷 基彦,吉井 恵,早川 哲平,深津 誠,仁科 淳良,鈴木 孝,栗田 雅弘
日本薬学会 第136年会, Mar. 2016, Not invited - メグスリノキ樹皮由来ジアリールヘプタノイド及びそれらの誘導体の細胞傷害活性及びメラニン産生抑制活性
横川悟,武田綾乃,赤澤寛行,渡辺賢介,菊地崇,浮谷基彦,秋久俊博,深津誠
日本生薬学会第58回年会, Sep. 2011, Not invited - ラノスタン型及びシクロアルタン型トリテルペンアルコール誘導体の細胞傷害活性及びアポトーシス誘導活性
石井健太,菊地崇,高橋菜実,浮谷基彦,秋久俊博,深津誠
日本生薬学会第58回年会, Sep. 2011, Not invited - 天然リモノイド及びそれらの誘導体の細胞傷害活性及びＮＯ産生抑制活性
松本将裕,中村康宏,菊地崇,西本有希,高橋章友,浮谷基彦,秋久俊博
日本生薬学会第58回年会, Sep. 2011, Not invited - アビエタン型ジテルペン誘導体の細胞傷害活性
川口拓真,浮谷基彦,荻原英里,菊地崇,秋久俊博,恵崎陽一郎
日本生薬学会第58回年会, Sep. 2011, Not invited - Cytotoxic and apoptosis-inducing activities of steviol derivatives against human cancer cell lines
Motohiko Ukiya; Shingo Sawada; Takashi Kikuchi; Ryosuke Koike; Takuma Kawaguchi; Keiichi Tabata; Takashi Suzuki; Toshihiro Akihisa
The 52nd Annual Meeting of the American Society of Pharmacognosy, Jul. 2011, Not invited - 茯苓由来酸性トリテルペン誘導体の細胞傷害およびアポトーシス誘導活性
菊地 崇,秋久俊博,浮谷基彦,内山恵美子,田畑恵市,鈴木 孝
日本薬学会第129年会, Mar. 2009, Not invited - 天然甘味料Steviosideを素材とした腫瘍細胞傷害活性を有する化合物の調製
浮谷基彦,秋久俊博,菊地崇,二瓶雅俊,木村由美子,田畑恵市,鈴木孝
第52回 香料・テルペンおよび精油化学に関する討論会, Oct. 2008, Not invited - アントラキノン誘導体の調製とその生物活性
澤田真吾,浮谷基彦,秋久俊博,菊地崇,二瓶雅俊,大久保慈,木村由美子,田畑恵市,鈴木孝,徳田春邦
日本薬学会第128年会, Mar. 2008, Not invited - ダンマル樹脂由来トリテルペノイドの抗発がんプロモーター活性および腫瘍細胞傷害活性
浮谷基彦,秋久俊博,徳田春邦,菊地崇,田畑恵市,木村由美子,恵崎陽一郎,大瀬戸治,鈴木孝
日本薬学会第128年会, Mar. 2008, Not invited - 天然トリテルペノイド化学構造修飾物のトポイソメラーゼ阻害活性及び腫瘍細胞傷害活性
浮谷基彦,秋久俊博,菊地崇,二瓶雅俊,木村由美子,鈴木孝
第51回 香料・テルペンおよび精油化学に関する討論会, Nov. 2007, Not invited - Cycloartane型トリテルペノイドの発がん予防効果
菊地 崇,秋久俊博,浮谷基彦,徳田春邦,西野輔翼
日本生薬学会, Sep. 2006, Not invited - ニガウリ果実抽出物からの新規ククルビタン型トリテルペノイド
肥後直樹,秋久俊博,浮谷基彦,木村由美子,鈴木 孝,徳田春邦(日大理工,日大薬,京都府医大)
第４５回日本油化学会年会, Sep. 2006, Not invited - ニガウリ果実トリテルペノイド成分の発がん予防効果
浮谷基彦、秋久俊博、徳田春邦、栃木祐一、木村由美子、鈴木 孝、西野輔翼(日大理工、京都府医大、日大薬)
第１２６年会日本薬学会, Mar. 2006, Not invited - マリーゴールド花弁成分の抗発がんプロモーター、抗炎症、および抗腫瘍活性
浮谷基彦、秋久俊博、徳田春邦、安川 憲、木村由美子、鈴木 孝
日本生薬学会第52回年会, Sep. 2005, Not invited - アシタバ黄汁からの新規カルコン類化合物とそれらの発がん予防効果
浮谷基彦、秋久俊博、徳田春邦、長谷川大輔、鈴木 孝、木村由美子、西野輔翼
第125年回 日本薬学会, Mar. 2005, Not invited - 大黄成分の抗発がんプロモーター活性
秋久俊博,徳田春邦,西野輔翼
第９回日本フードファクター学会, Dec. 2004, Not invited - ニガウリ果実脂質成分の発がん予防効果
浮谷基彦,秋久俊博,徳田春邦,西野輔翼
第４３回日本油化学会年会, Nov. 2004, Not invited - Anti-tumor promoting effects and cytotoxic activities against human cancer cell lines of triterpene glycosidesand flavonol glycosides from marigold (Calendula officinalis L.) flowers.
Toshihiro Akihisa; Harukuni Tokuda; Yumiko Kimura; Takashi Suzuki; Hoyoku Nishino
2004 International Congress on Natural Products Research, Aug. 2004, Not invited - ニガウリ果実成分の構造と発がん予防効果
秋久俊博,湯浅紀子,早川陽佑,徳田春邦,西野輔翼,木村由美子,鈴木 孝
第11回日本がん予防研究会, Jul. 2004, Not invited - マリーゴールド花弁抽出成分の抗発がんプロモーター活性
秋久俊博,川村 愛、徳田春邦,西野輔翼、木村由美子,鈴木 孝
第124年会 日本薬学会, Mar. 2004, Not invited - ツバキ油不ケン化脂質の抗発がんプロモーター活性
秋久俊博、徳田春邦,西野穂翼、鈴木敏江
第42回日本油化学会年会, Sep. 2003, Not invited - ツバキ油不ケン化脂質成分の抗発がんプロモーター活性
浮谷基彦,秋久俊博,渡辺健二、鈴木敏江、徳田春邦,西野輔翼
第10回日本がん予防研究会, Jun. 2003, Not invited - 紅麹色素成分の抗発がんプロモーター活性
秋久俊博,真船祥一、徳田春邦,西野輔翼、田辺伸和,福岡忠彦
日本フードファクター学会第7回学術集会, Nov. 2002, Not invited - マンボウ肝油由来高度不飽和脂肪酸メチルエステルの抗発がんプロモーター活性
浮谷基彦,秋久俊博、徳田春邦,緒形正和,西野輔翼
第41回日本油化学会年会, Sep. 2002, Not invited - 小菊（白菊）抽出成分の抗発がんプロモーター活性
奥田浩貴,秋久俊博、徳田春邦,西野輔翼、阿曽田清
第9回日本がん予防研究会, Jul. 2002, Not invited - ひまわり花粉脂質成分の抗発がんプロモーター活性
秋久俊博、徳田春邦,西野輔翼、木村由美子、小池一男、二階堂保
日本フードファクター学会第６回学術集会, Nov. 2001, Not invited - ひまわり花粉テルペノイド成分の抗発がんプロモーター活性
浮谷基彦,秋久俊博、徳田春邦,西野輔翼、木村由美子、小池一男,二階堂保
第40回日本油化学会年会, Oct. 2001, Not invited - キク科植物花弁トリテルペノイド成分の抗発がんプロモーター活性
浮谷基彦,秋久俊博、徳田春邦,西野輔翼、安川憲、笠原義正
第8回日本がん予防研究会, Jul. 2001, Not invited - 食用菊のジーおよびトリヒドロキシトリテルペノイド成分の抗発がんプロモーター活性
秋久俊博、徳田春邦,西野輔翼、安川憲、笠原義正
日本フードファクター学会第５回学術集会, Nov. 2000, Not invited - Lipid Constituents of the Pollen Grains of Sunflower(Helianthus annuus L.)
Okuda; T. Akihisa; Y. Kimura; H. Tokuda; H. Nishino; K. Koike
Japan Oil Chemists’ Society American Oil Chemists’ Society World Congress 2000, Oct. 2000, Not invited
