Doctor of Medical Science, Keio University, Mar. 2016

Life sciences, Tumor biology

Apr. 2022 - Present
Nihon University, School of Dentistry, Assistant Professor

Sep. 2018 - Mar. 2022
Tokyo University of Science, Research Institute for Biomedical Sciences, Assistant Professor

Apr. 2016 - Aug. 2018
Keio University, Division of Gene Regulation, Institute for Advanced Medical Research, Graduate School of Medicine, Project Assistant Professor

Apr. 2012 - Mar. 2016
Keio University, 医学研究科

Apr. 2010 - Mar. 2012
Kinki University, 薬学研究科

Apr. 2006 - Mar. 2010
Kindai University, Faculty of Pharmacy, Department of Pharmaceutical Sciences

Sep. 2025
日本歯科医学会, 第25回⽇本⻭科医学会学術⼤会ポスター賞
治療抵抗性頭頸部扁平上皮癌を標的とした治療薬の同定

Drug Repurposing Screen Identifies Pimozide as a ROS-Inducing Therapy With Anti-Tumor Efficacy in HNSCC PDX Models.
Shogo Okazaki; Shintaro Nakamura; Tomoya Soma; Momoko Yoshikawa; Seiji Asoda; Yurika Nakajima; Kenji Tsuchihashi; Mitsuyo Ohmura; Ryo Goitsuka; Kenichi Imai; Hideyuki Saya; Osamu Nagano; Hiroyuki Ozawa
Cancer science, Nov. 2025

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition.
Yurika Nakajima; Shogo Okazaki; Muneaki Tamura; Shuichi Sato; Kenichi Imai
FEBS open bio, Nov. 2025

治療抵抗性頭頸部扁平上皮癌を標的とした治療薬の同定
岡崎 章悟; 吉川 桃子; 相馬 智也; 莇生田 整治; 中島 由梨佳; 今井 健一
日本歯科医師会雑誌, Jul. 2025

口腔微小環境は口腔扁平上皮癌の進展に影響する
中島 由梨佳; 岡崎 章悟; 今井 健一; 佐藤 秀一
日本歯科医師会雑誌, Jul. 2025

Benzaldehyde suppresses epithelial-mesenchymal plasticity and overcomes treatment resistance in cancer by targeting the interaction of 14-3-3ζ with H3S28ph.
Jun Saito; Nobuyuki Onishi; Juntaro Yamasaki; Naoyoshi Koike; Yukie Hata; Kiyomi Kimura; Yuji Otsuki; Hiroyuki Nobusue; Oltea Sampetrean; Takatsune Shimizu; Shogo Okazaki; Eiji Sugihara; Hideyuki Saya
British journal of cancer, May 2025

Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions.
Yuka Nozaki; Masaki Kobayashi; Tomoyoshi Fukuoh; Mamiko Ishimatsu; Takumi Narita; Kanari Taki; Yuto Hirao; Shota Ayabe; Miku Yokoyama; Yuina Otani; Yuhei Mizunoe; Mami Matsumoto; Nobuhiko Ohno; Tomonori Kaifu; Shogo Okazaki; Ryo Goitsuka; Yoshimi Nakagawa; Hitoshi Shimano; Yoichiro Iwakura; Yoshikazu Higami
Scientific reports, Apr. 2025

CD44v, S1PR1, HER3, MET and cancer-associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb.
Takashi Nakano; Kouki Okita; Shogo Okazaki; Soshi Yoshimoto; Sachiko Masuko; Hideki Yagi; Kazunori Kato; Yoshihisa Tomioka; Kenichi Imai; Yoichi Hamada; Kazue Masuko; Kayoko Shimada-Takaura; Noriaki Nagai; Hideyuki Saya; Tomio Arai; Toshiyuki Ishiwata; Takashi Masuko
FEBS open bio, Jan. 2025

B Cells of Early-life Origin Defined by RAG2-based Lymphoid Cell Tracking under Native Hematopoietic Conditions.
Keiko Fujisaki; Shogo Okazaki; Shuhei Ogawa; Miyama Takeda; Eiji Sugihara; Kenichi Imai; Seiya Mizuno; Satoru Takahashi; Ryo Goitsuka
Journal of immunology (Baltimore, Md. : 1950), Jun. 2024

The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor.
Atsuya Sawabe; Shogo Okazaki; Akira Nakamura; Ryo Goitsuka; Tomonori Kaifu
Journal of leukocyte biology, Jan. 2024

CD98 regulates the phosphorylation of HER2 and a bispecific anti‐HER2 / CD98 antibody inhibits the growth signal of human breast cancer cells
Akitaka Yamasaki; Kumiko Maruyama‐Takahashi; Kento Nishida; Shogo Okazaki; Kouki Okita; Yasutoshi Akiyama; Hideaki Suzuki; Yuichi Endo; Kazue Masuko; Takashi Masuko; Yoshihisa Tomioka
Genes to Cells, Feb. 2023

Dual‐targeting therapy against HER3 / MET in human colorectal cancers
Akitaka Yamasaki; Rikuto Miyake; Yuta Hara; Hideki Okuno; Takuya Imaida; Kouki Okita; Shogo Okazaki; Yasutoshi Akiyama; Kenji Hirotani; Yuichi Endo; Kazue Masuko; Takashi Masuko; Yoshihisa Tomioka
Cancer Medicine, Feb. 2023

MEK inhibition suppresses metastatic progression of KRAS-mutated gastric cancer.
Juntaro Yamasaki; Yuki Hirata; Yuji Otsuki; Kentaro Suina; Yoshiyuki Saito; Kenta Masuda; Shogo Okazaki; Takatsugu Ishimoto; Hideyuki Saya; Osamu Nagano
Cancer science, Mar. 2022

口腔扁平上皮癌においてFOXA1発現はxCT依存的腫瘍成長を抑制する
岡崎 章悟; 中野 友暉; 吉川 桃子; 相馬 智也; 莇生田 整治; 後飯塚 僚; 佐谷 秀行; 永野 修
日本癌学会総会記事, Sep. 2021

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target
Natsumi Hayashi; Akitaka Yamasaki; Shiho Ueda; Shogo Okazaki; Yoshiya Ohno; Toshiyuki Tanaka; Yuichi Endo; Yoshihisa Tomioka; Kazue Masuko; Takashi Masuko; Reiko Sugiura
Oncotarget, Jun. 2021

Antitumor effects of novel mAbs against cationic amino acid transporter 1 (CAT1) on human CRC with amplified CAT1 gene.
Kouki Okita; Yuta Hara; Hiroshi Okura; Hidemi Hayashi; Yoko Sasaki; Sachiko Masuko; Eri Kitadai; Kazue Masuko; Soshi Yoshimoto; Natsumi Hayashi; Reiko Sugiura; Yuichi Endo; Shogo Okazaki; Sayaka Arai; Toshiaki Yoshioka; Toshiharu Matsumoto; Yasutaka Makino; Hiromitsu Komiyama; Kazuhiro Sakamoto; Takashi Masuko
Cancer science, Feb. 2021

The Inhibitor of Apoptosis Protein Livin Confers Resistance to Fas-Mediated Immune Cytotoxicity in Refractory Lymphoma.
Eiji Sugihara; Norisato Hashimoto; Satoru Osuka; Takatsune Shimizu; Sayaka Ueno; Shogo Okazaki; Tomonori Yaguchi; Yutaka Kawakami; Kenjiro Kosaki; Taka-Aki Sato; Shinichiro Okamoto; Hideyuki Saya
Cancer research, Oct. 2020

Author Correction: CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake.
Nana Kobayashi; Shogo Okazaki; Oltea Sampetrean; Junichiro Irie; Hiroshi Itoh; Hideyuki Saya
Scientific reports, Apr. 2020, Refereed, Not invited

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers.
Kouki Okita; Shogo Okazaki; Shinya Uejima; Erina Yamada; Hiroki Kaminaka; Misa Kondo; Shiho Ueda; Ryo Tokiwa; Nami Iwata; Akitaka Yamasaki; Natsumi Hayashi; Dai Ogura; Kenji Hirotani; Toshiaki Yoshioka; Masahiro Inoue; Kazue Masuko; Takashi Masuko
Oncotarget, Jan. 2020, Refereed, Not invited

Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy.
Yuji Otsuki; Juntaro Yamasaki; Kentaro Suina; Shogo Okazaki; Naoyoshi Koike; Hideyuki Saya; Osamu Nagano
Cancer science, Jan. 2020, Refereed, Not invited

Transcription factor Tlx1 marks a subset of lymphoid tissue organizer-like mesenchymal progenitor cells in the neonatal spleen.
Yuta Ueno; Keiko Fujisaki; Shoko Hosoda; Yusuke Amemiya; Shogo Okazaki; Chihiro Notsu; Chiharu Nishiyama; Yo Mabuchi; Yumi Matsuzaki; Akihisa Oda; Ryo Goitsuka
Scientific reports, Dec. 2019, Refereed, Not invited

Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma.
Shogo Okazaki; Kiyoko Umene; Juntaro Yamasaki; Kentaro Suina; Yuji Otsuki; Momoko Yoshikawa; Yushi Minami; Takashi Masuko; Sho Kawaguchi; Hideki Nakayama; Kouji Banno; Daisuke Aoki; Hideyuki Saya; Osamu Nagano
Cancer science, Nov. 2019, Refereed, Not invited

小細胞肺癌において、xCTはがん幹細胞性に寄与する(xCT confers cancer stem-like properties in small cell lung cancer cells)
推名 健太郎; 山崎 淳太郎; 大槻 雄士; 平田 雄紀; 岡崎 章悟; 土橋 賢司; サンペトラ・オルテア; 光石 陽一郎; 高橋 史行; 高橋 和久; 佐谷 秀行; 永野 修
日本癌学会総会記事, Sep. 2019

Benzaldehydeは腫瘍細胞における14-3-3ζの高発現を介してAMPK活性を亢進させる(Benzaldehyde activates AMPK via cancer specific upregulated 14-3-3ζ)
齋藤 潤; 大西 伸幸; 杉原 英志; 清水 孝恒; 木村 聖美; 小池 直義; サンペトラ・オルテア; 岡崎 章悟; 信末 博行; 笠間 隆志; 佐谷 秀行
日本癌学会総会記事, Sep. 2019

Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension.
Sarasa Isobe; Masaharu Kataoka; Jin Endo; Hidenori Moriyama; Shogo Okazaki; Kenji Tsuchihashi; Yoshinori Katsumata; Tsunehisa Yamamoto; Kohsuke Shirakawa; Naohiro Yoshida; Masayuki Shimoda; Tomohiro Chiba; Takashi Masuko; Yoji Hakamata; Eiji Kobayashi; Hideyuki Saya; Keiichi Fukuda; Motoaki Sano
American journal of respiratory cell and molecular biology, Sep. 2019, Refereed, Not invited

Sulfasalazine could modulate the CD44v9-xCT system and enhance cisplatin-induced cytotoxic effects in metastatic bladder cancer.
Koichiro Ogihara; Eiji Kikuchi; Shogo Okazaki; Masayuki Hagiwara; Toshikazu Takeda; Kazuhiro Matsumoto; Takeo Kosaka; Shuji Mikami; Hideyuki Saya; Mototsugu Oya
Cancer science, Apr. 2019, Refereed, Not invited

Clinicopathological findings and molecular profile of gastric cancer with a gastric mucin phenotype 胃型腫瘍の臨床病理と分子異常 オルガノイド技術と遺伝子操作を用いた新たな胃癌モデルの作成(Clinicopathological findings and molecular profile of gastric cancer with a gastric mucin phenotype A novel gastric cancer mouse model by using organoid technique and genetic manipulation)
平田 雄紀; 永野 修; 齋藤 慶幸; 山崎 淳太郎; 新谷 昴; 推名 健太郎; 岡崎 章悟; 佐谷 秀行; 川久保 博文; 北川 雄光
日本胃癌学会総会記事, Feb. 2019

Anti-tumor effects of mAb against L-type amino acid transporter 1 (LAT1) bound to human and monkey LAT1 with dual avidity modes.
Shiho Ueda; Hidemi Hayashi; Takako Miyamoto; Shinya Abe; Kana Hirai; Kanji Matsukura; Hideki Yagi; Yuta Hara; Kinji Yoshida; Shogo Okazaki; Masakazu Tamura; Yuki Abe; Toshinori Agatsuma; Shin-Ichiro Niwa; Kazue Masuko; Takashi Masuko
Cancer science, Feb. 2019, Refereed, Not invited

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling.
Kentaro Suina; Kenji Tsuchihashi; Juntaro Yamasaki; Shohei Kamenori; Subaru Shintani; Yuki Hirata; Shogo Okazaki; Oltea Sampetrean; Eishi Baba; Koichi Akashi; Yoichiro Mitsuishi; Fumiyuki Takahashi; Kazuhisa Takahashi; Hideyuki Saya; Osamu Nagano
Cancer science, Dec. 2018, Refereed, Not invited

Synthetic lethality of the ALDH3A1 inhibitor dyclonine and xCT inhibitors in glutathione deficiency-resistant cancer cells.
Shogo Okazaki; Subaru Shintani; Yuki Hirata; Kentaro Suina; Takashi Semba; Juntaro Yamasaki; Kiyoko Umene; Miyuki Ishikawa; Hideyuki Saya; Osamu Nagano
Oncotarget, Sep. 2018, Refereed, Not invited

Benzaldehydeは腫瘍細胞の主要シグナルとE2Fによる転写機能を癌細胞にて過剰発現する14-3-3ζを介して抑制する(Benzaldehyde inhibits the multiple signals and E2F transcription in cancer cells by suppression of overexpressed 14-3-3ζ)
齋藤 潤; 大西 伸幸; 杉原 英志; 岡崎 章悟; 信末 博行; 笠間 隆志; 佐谷 秀行
日本癌学会総会記事, Sep. 2018

CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake.
Nana Kobayashi; Shogo Okazaki; Oltea Sampetrean; Junichiro Irie; Hiroshi Itoh; Hideyuki Saya
Scientific reports, Feb. 2018, Refereed, Not invited

xCT promotes malignant phenotypes in EGFR-expressing glioma
Tsuchihashi Kenji; Okazaki Shogo; Yoshikawa Momoko; Seishima Ryo; Sampetrean Oltea; Onishi Nobuyuki; Wakimoto Hiroaki; Furnari Frank; Baba Eishi; Akashi Koichi; Saya Hideyuki; Nagano Osamu
CANCER RESEARCH, Jul. 2017, Refereed, Not invited

Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.
Shin Kasai; Yoshiyuki Furuichi; Norie Ando; Keiko Kagami; Masako Abe; Takaya Nakane; Kumiko Goi; Takeshi Inukai; Sei Saitoh; Shinichi Ohno; Shogo Okazaki; Osamu Nagano; Hideyuki Saya; Kanji Sugita
Cell death & disease, Jun. 2017, Refereed, Not invited

CD44 variant-dependent redox status regulation in liver fluke-associated cholangiocarcinoma: A target for cholangiocarcinoma treatment.
Malinee Thanee; Watcharin Loilome; Anchalee Techasen; Eiji Sugihara; Shogo Okazaki; Shinya Abe; Shiho Ueda; Takashi Masuko; Nisana Namwat; Narong Khuntikeo; Attapol Titapun; Chawalit Pairojkul; Hideyuki Saya; Puangrat Yongvanit
Cancer science, Jul. 2016, Refereed, Not invited

The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
Kenji Tsuchihashi; Shogo Okazaki; Mitsuyo Ohmura; Miyuki Ishikawa; Oltea Sampetrean; Nobuyuki Onishi; Hiroaki Wakimoto; Momoko Yoshikawa; Ryo Seishima; Yoshimi Iwasaki; Takayuki Morikawa; Shinya Abe; Ayumi Takao; Misato Shimizu; Takashi Masuko; Motoo Nagane; Frank B Furnari; Tetsu Akiyama; Makoto Suematsu; Eishi Baba; Koichi Akashi; Hideyuki Saya; Osamu Nagano
Cancer research, May 2016, Refereed, Not invited

Development of an ErbB4 monoclonal antibody that blocks neuregulin-1-induced ErbB4 activation in cancer cells.
Shogo Okazaki; Fumi Nakatani; Kazue Masuko; Kenji Tsuchihashi; Shiho Ueda; Takashi Masuko; Hideyuki Saya; Osamu Nagano
Biochemical and biophysical research communications, Jan. 2016, Refereed, Not invited

Ink4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis.
Ryo Seishima; Takeyuki Wada; Kenji Tsuchihashi; Shogo Okazaki; Momoko Yoshikawa; Hiroko Oshima; Masanobu Oshima; Toshiro Sato; Hirotoshi Hasegawa; Yuko Kitagawa; James R Goldenring; Hideyuki Saya; Osamu Nagano
Cancer prevention research (Philadelphia, Pa.), Jun. 2015, Refereed, Not invited

NIH3T3 cells overexpressing CD98 heavy chain resist early G1 arrest and apoptosis induced by serum starvation.
Kaori Hara; Shiho Ueda; Yoshiya Ohno; Toshiyuki Tanaka; Hideki Yagi; Shogo Okazaki; Rieko Kawahara; Takechi Masayuki; Takemi Enomoto; Yoshiyuki Hashimoto; Kazue Masuko; Takashi Masuko
Cancer science, Aug. 2012, Refereed, Not invited

Anti-tumor effect against human cancer xenografts by a fully human monoclonal antibody to a variant 8-epitope of CD44R1 expressed on cancer stem cells.
Kazue Masuko; Shogo Okazaki; Mayumi Satoh; Goh Tanaka; Tatsuya Ikeda; Ryota Torii; Eri Ueda; Takashi Nakano; Masaaki Danbayashi; Tomoyo Tsuruoka; Yoshiya Ohno; Hideki Yagi; Noritsugu Yabe; Hideaki Yoshida; Tomoyuki Tahara; Shiro Kataoka; Taichi Oshino; Takayuki Shindo; Shin-ichiro Niwa; Takatsugu Ishimoto; Hideo Baba; Yoshiyuki Hashimoto; Hideyuki Saya; Takashi Masuko
PloS one, 2012, Refereed, Not invited

Oncogenicity of L-type amino-acid transporter 1 (LAT1) revealed by targeted gene disruption in chicken DT40 cells: LAT1 is a promising molecular target for human cancer therapy.
Mayumi Ohkawa; Yoshiya Ohno; Kazue Masuko; Akiko Takeuchi; Kentaro Suda; Akihiro Kubo; Rieko Kawahara; Shogo Okazaki; Toshiyuki Tanaka; Hideyuki Saya; Masayuki Seki; Takemi Enomoto; Hideki Yagi; Yoshiyuki Hashimoto; Takashi Masuko
Biochemical and biophysical research communications, Mar. 2011, Refereed, Not invited

口腔微小環境は口腔扁平上皮癌の進展に影響する
中島由梨佳; 岡崎章悟; 今井健一; 佐藤秀一
日本歯科医師会雑誌, 2025

スフェロイド培養とHippo経路阻害剤を用いた口腔扁平上皮癌細胞株-Porphyromonas gingivalis共培養系の樹立とその応用
中島由梨佳; 中島由梨佳; 岡崎章悟; 今井健一; 佐藤秀一
日本歯周病学会会誌(Web), 2024

スフェロイド培養とHippo経路阻害剤を用いた口腔扁平上皮癌細胞株-Porphyromonas gingivalis共培養系の樹立とその応用
中島由梨佳; 中島由梨佳; 岡崎章悟; 岡崎章悟; 今井健一; 今井健一; 佐藤秀一; 佐藤秀一
日大歯学(Web), 2024

Proposal of promising target proteins for the diagnosis and therapy of pancreatic cancers defined by mAb
沖田鋼季; 沖田鋼季; 岡崎章悟; 中埜尚; 加藤和則; 八木秀樹; 富岡佳久; 長井紀章; 佐谷秀行; 石渡俊行; 益子高; 益子高
日本癌学会学術総会抄録集(Web), 2024

Porphyromonas gingivalisが口腔扁平上皮癌におけるFOXA1発現に及ぼす影響
中島由梨佳; 中島由梨佳; 岡崎章悟; 今井健一; 佐藤秀一
日本歯周病学会会誌(Web), 2023

スフェロイド培養を用いた口腔扁平上皮癌-歯周病原性細菌共培養系の樹立
中島由梨佳; 中島由梨佳; 岡崎章悟; 田村宗明; 佐藤秀一; 今井健一
Journal of Oral Biosciences Supplement (Web), 2023

Establishment of an oral squamous cell carcinoma-periodontopathogenic bacteria co-culture system using spheroid culture
中島由梨佳; 中島由梨佳; 岡崎章悟; 佐藤秀一; 今井健一
日本癌学会学術総会抄録集(Web), 2023

P.gingivalis Mfa1線毛はTLR-2を介して呼吸器上皮細胞からの炎症性サイトカイン産生を誘導する
中島由梨佳; 岡崎章悟; 岡崎章悟; 今井健一; 今井健一; 長谷川義明; 佐藤秀一; 佐藤秀一
日本歯周病学会会誌(Web), 2023

Transcription factor FOXA1 is a negative regulator for xCT-dependent tumor formation in oral cancer
Shogo Okazaki; Yuki Nakano; Momoko Yoshikawa; Tomoya Soma; Seiji Asoda; Ryo Goitsuka; Hideyuki Saya; Osamu Nagano
CANCER SCIENCE, Feb. 2022

Decreased expression of FOXA1 promotes tumor growth and xCT dependency in oral squamous cell carcinoma.
岡崎章悟; 中島由梨佳; 吉川桃子; 相馬智也; 莇生田整治; 今井健一; 後飯塚僚; 佐谷秀行; 永野修
日本分子生物学会年会プログラム・要旨集(Web), 2022

FOXA1 suppresses oral cancer progression through inhibiting p38 activation induced by lipid-derived aldehydes
岡崎章悟; 吉川桃子; 相馬智也; 莇生田整治; 今井健一; 後飯塚僚; 佐谷秀行; 永野修
日本癌学会学術総会抄録集(Web), 2022

Benzaldehydeは癌細胞のAxl受容体の発現を14-3-3ζを介して抑制し,Osimertinibによる治療抵抗性を制する
齋藤潤; 齋藤潤; 大西伸幸; 杉原英志; 清水孝恒; 清水孝恒; 木村聖美; 小池直義; 小池直義; サンペトラ オルテア; 岡崎章悟; 信末博行; 笠間隆志; 佐谷秀行
日本癌学会学術総会抄録集(Web), 2021

Pimozide combined with paclitaxel demonstrates a significant antitumor effect in head and neck squamous cell carcinoma
Shintaro Nakamura; Hiroyuki Ozawa; Juntaro Yamasaki; Shogo Okazaki; Momoko Yoshikawa; Tomoya Soma; Seiji Asoda; Osamu Nagano; Mariko Sekimizu; Shin Saito; Keisuke Yoshihama; Takuya Mikoshiba; Kaoru Ogawa; Hideyuki Saya
CANCER RESEARCH, Aug. 2020

小細胞肺癌において、xCTはがん幹細胞性に寄与する(xCT confers cancer stem-like properties in small cell lung cancer cells)
推名 健太郎; 山崎 淳太郎; 大槻 雄士; 平田 雄紀; 岡崎 章悟; 土橋 賢司; サンペトラ・オルテア; 光石 陽一郎; 高橋 史行; 高橋 和久; 佐谷 秀行; 永野 修
日本癌学会総会記事, Sep. 2019, Not refereed, Not invited

SLC7A11 expression confers cancer stem-like properties in small cell lung cancer cells
Shohei Kamenori; Kentaro Suina; Juntaro Yamasaki; Subaru Shintani; Yuji Otsuki; Yuki Hirata; Shogo Okazaki; Kenji Tsuchihashi; Oltea Sampetrean; Yoichiro Mitsuishi; Fumiyuki Takahashi; Kazuhisa Takahashi; Hideyuki Saya; Osamu Nagano
CANCER RESEARCH, Jul. 2019, Not refereed, Not invited

Clinicopathological findings and molecular profile of gastric cancer with a gastric mucin phenotype 胃型腫瘍の臨床病理と分子異常 オルガノイド技術と遺伝子操作を用いた新たな胃癌モデルの作成(Clinicopathological findings and molecular profile of gastric cancer with a gastric mucin phenotype A novel gastric cancer mouse model by using organoid technique and genetic manipulation)
平田 雄紀; 永野 修; 齋藤 慶幸; 山崎 淳太郎; 新谷 昴; 推名 健太郎; 岡崎 章悟; 佐谷 秀行; 川久保 博文; 北川 雄光
日本胃癌学会総会記事, Feb. 2019, Not refereed, Not invited

Benzaldehyde activates AMPK via cancer specific upregulated 14-3-3ζ
齋藤潤; 齋藤潤; 大西伸幸; 杉原英志; 清水孝恒; 清水孝恒; 木村聖美; 小池直義; 小池直義; サンペトラ オルテア; 岡崎章悟; 信末博行; 笠間隆志; 佐谷秀行
日本癌学会学術総会抄録集(Web), 2019

A novel gastric cancer mouse model by using organoid technique and genetic manipulation
Yuki Hirata; Osamu Nagano; Yoshiyuki Saito; Juntaro Yamasaki; Subaru Shintani; Kentaro Suina; Shogo Okazaki; Hirofumi Kawakubo; Hideyuki Saya; Yuko Kitagawa
CANCER SCIENCE, Dec. 2018, Not refereed, Not invited

The establishment of new therapeutic strategy for metastatic urothelial carcinoma targeting against cancer stem cell
Koichiro Ogihara; Eiji Kikuchi; Kyohei Hakozaki; Shogo Okazaki; Masayuki Hagiwara; Toshikazu Takeda; Kazuhiro Matsumoto; Takeo Kosaka; Shuji Mikami; Hideyuki Saya; Mototsugu Oya
INTERNATIONAL JOURNAL OF UROLOGY, Oct. 2018

オルガノイド技術を用いた、遺伝子操作による新しい型胃癌モデルの作成(A novel gastric cancer mouse model by using organoid technique and genetic manipulation)
平田 雄紀; 永野 修; 齋藤 慶幸; 山崎 淳太郎; 新谷 昴; 推名 健太郎; 岡崎 章悟; 川久保 博文; 佐谷 秀行; 北川 雄光
日本癌学会総会記事, Sep. 2018, Not refereed, Not invited

オルガノイドを用いた新しい胃癌モデルの作成と悪性化メカニズムの解明
平田 雄紀; 永野 修; 齋藤 慶幸; 山崎 淳太郎; 新谷 昴; 推名 健太郎; 岡崎 章悟; 佐谷 秀行; 北川 雄光
日本癌治療学会学術集会抄録集, Oct. 2017, Not refereed, Not invited

脳腫瘍に対する酸化ストレス回避機構を標的にした治療法の開発
土橋賢司; 土橋賢司; 岡崎章悟; 大村光代; SAMPETREAN Oltea; 大西伸幸; 益子高; 馬場英司; 赤司浩一; 佐谷秀行; 永野修
日本臨床腫瘍学会学術集会(CD-ROM), 2017

xCTの阻害はCD44v発現グルタミン依存性口腔扁平上皮癌細胞におけるレドックスホメオスタシスを破綻させる
岡崎 章悟; 土橋 賢司; 吉川 桃子; 佐谷 秀行; 永野 修
日本癌学会総会記事, Oct. 2016, Not refereed, Not invited

EGFRはアミノ酸トランスポーターxCTを介して脳腫瘍の悪性化を促進する
土橋 賢司; 岡崎 章悟; 大村 光代; サンペトラ・オルテア; 大西 伸幸; 吉川 桃子; 清島 亮; 益子 高; 末松 誠; 馬場 英司; 赤司 浩一; 佐谷 秀行; 永野 修
日本癌学会総会記事, Oct. 2016, Not refereed, Not invited

EGFRはシスチン・グルタミン酸交換輸送体xc(-)系を制御して神経膠芽腫細胞の悪性化を促進する
山崎淳太郎; 土橋賢司; 土橋賢司; 推名健太郎; 岡崎章悟; 佐谷秀行; 永野修
日本分子生物学会年会プログラム・要旨集(Web), 2016

ピモジドはCD44v陽性幹細胞様がん細胞において酸化ストレスを誘導し、抗腫瘍活性を示す
岡崎 章悟; 土橋 賢司; 吉川 桃子; 佐谷 秀行; 永野 修
日本癌学会総会記事, Oct. 2015, Not refereed, Not invited

Redox regulation in stem-like cancer cells by CD44 variant isoforms
O. Nagano; S. Okazaki; H. Saya
Oncogene, 31 Oct. 2013, Not refereed, Not invited

歯周病発症機序のパラダイムシフトへの挑戦 ーヒト化マウスでのウイルス関与の立証 ー
日本学術振興会, 科学研究費助成事業, 28 Jun. 2024 - 31 Mar. 2027
今井 健一; 岡崎 章悟; 蓮池 聡

J鎖依存的に腸管粘膜固有層で分化する分泌型IgA産生細胞の起源ならびに機能の解明
日本学術振興会, 科学研究費助成事業, 01 Apr. 2024 - 31 Mar. 2027
後飯塚 僚; 岡崎 章悟

PDXモデルを用いた局所進行・再発転移口腔癌に対する新たな治療戦略の考案
日本学術振興会, 科学研究費助成事業, 01 Apr. 2023 - 31 Mar. 2026
吉川 桃子; 莇生田 整治; 岡崎 章悟; 小澤 宏之; 佐谷 秀行

セロトニンシグナルを標的とした扁平上皮癌分化誘導療法の開発
日本学術振興会, 科学研究費助成事業, 01 Apr. 2022 - 31 Mar. 2025
岡崎 章悟; 莇生田 整治; 吉川 桃子; 相馬 智也

Actionable遺伝子変異に基づく新たな口腔扁平上皮癌治療戦略の開発
日本学術振興会, 科学研究費助成事業, 01 Apr. 2022 - 31 Mar. 2025
莇生田 整治; 岡崎 章悟; 黄地 健仁; 吉川 桃子; 佐谷 秀行

Functional analysis of serotonin signaling in the progression of squamous cell carcinoma
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2020 - 31 Mar. 2022
Okazaki Shogo

Analysis of antitumor effect mechanism by dopamine signal inhibitor
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, 01 Apr. 2018 - 31 Mar. 2020
Okazaki Shogo

癌幹細胞におけるＣＤ４４ｖを介したグルタミン酸放出の意義
日本学術振興会, 科学研究費助成事業 特別研究員奨励費, 25 Apr. 2014 - 31 Mar. 2016
岡崎 章悟