Enzyme Engineering

D-Amino acid

合成生物学

Fermentation Engineering

微生物系統分類学

Life sciences, Applied microbiology

Apr. 2023 - Present
Nihon University, Department of Basic Science, College of Industrial Technology, 助教

Jul. 2022 - Mar. 2023
国立研究開発法人産業技術総合研究所, 社会実装本部, 企画主幹

Oct. 2018 - Mar. 2023
National Institute of Advanced Industrial Science and Technology, 機能化学研究部門, 主任研究員

Nov. 2021 - Jun. 2022
国立研究開発法人産業技術総合研究所, イノベーション推進本部, 企画主幹

Apr. 2021 - Aug. 2021
National Institute of Technology, Kure College, Faculty of Civil & Environmental Engineering, 非常勤講師

Apr. 2015 - Sep. 2018
National Institute of Advanced Industrial Science and Technology, 機能化学研究部門, 研究員

Apr. 2014 - Mar. 2015
National Institute of Advanced Industrial Science and Technology, バイオマスリファイナリー研究センター, 研究員

Apr. 2013 - Mar. 2014
日本学術振興会 特別研究員 (DC2)

Apr. 2011 - Mar. 2014
Kyushu University, Graduate School of Bioresource and Bioenvironmental Sciences, Department of Bioscience and Biotechnology

Apr. 2009 - Mar. 2011
Kyushu University, Graduate School of Bioresource and Bioenvironmental Sciences, 遺伝子資源工学専攻 (修士)

Apr. 2008 - Mar. 2009
Chiba Institute of Technology, Faculty of Engineering, 生命環境科学科 (研究生)

Apr. 2004 - Mar. 2008
Chiba Institute of Technology, Faculty of Engineering, 生命環境科学科 (学士)

Aug. 2023 - Present

Jun. 2023 - Present

Jul. 2021 - Present

Jan. 2021 - Dec. 2023

Mar. 2023 - Jun. 2023

Nov. 2023
公益財団法人コーセーコスメトロジー研究財団, 2023年度コスメトロジー研究助成
秋田紘長

Jun. 2023
日本海水学会, 2023年度日本海水学会第74年会 最優秀賞
秋田紘長

Nov. 2022
環境バイオテクノロジー学会, 2022年度 奨励賞
秋田紘長

Nov. 2021
酵素工学研究会, 2021年度 酵素工学奨励賞
秋田紘長

Jul. 2017
The D-Amino Acid Research Society, Award
Akita Hironaga

Feb. 2017
Inoue Foundation for Science, Inoue Research Award for Young Scientists
Akita Hironaga

Mar. 2014
Kyushu University, Award
Akita Hironaga

A short review of second-generation isobutanol production by SHF and SSF
Hironaga Akita; Akinori Matsushika
Applied Biosciences, Jul. 2024, Refereed, Invited
Lead

Utilization of seawater for isobutanol production
Hironaga Akita; Shodai Shibata; Tomoe Komoriya; Shinnosuke Kamei; Hiromichi Asamoto; Masakazu Matsumoto
Salt and Seawater Science & Technology, Jul. 2024, Refereed, Not invited
Lead

Inhibitor tolerance capacity of Pichia kudriavzevii NBRC1279 and NBRC1664
Hironaga Akita; Akinori Matsushika
Fermentation, Jun. 2024, Refereed, Not invited
Lead

Simultaneous saccharification and fermentation for isobutanol production from banana peel
Simultaneous Saccharification; Fermentation for Isobutanol; Production from Banana Peel
Fermentation, Mar. 2024, Refereed, Not invited
Lead

Isolation, draft genome sequence, and identification of Paenibacillus glycanilyticus subsp. hiroshimensis CCS26
Hironaga Akita; Yoshiki Shinto; Zen-ichiro Kimura
Journal of Genomics, Sep. 2023, Refereed, Not invited
Lead

Isolation and draft genome sequence of Paenibacillus sp. CCS19
Hironaga Akita; Yoshiki Shinto; Zen-ichiro Kimura
Journal of Genomics, Jul. 2023, Refereed, Not invited
Lead

Transcription analysis of the acid tolerance mechanism of Pichia kudriavzevii NBRC1279 and NBRC1664
Hironaga Akita; Akinori Matsushika
Fermentation, Jun. 2023, Refereed, Not invited
Lead

Analysis of the Bacterial Community of Metal Scrap Using an Enrichment Culture Approach
Hironaga Akita; Yoshiki Shinto; Zen-ichiro Kimura
Applied Biosciences, Jan. 2023, Refereed
Lead

Bacterial community analysis of biofilm formed on metal joint
Hironaga Akita; Yoshiki Shinto; Zen-ichiro Kimura
Applied Biosciences, Sep. 2022, Refereed
Lead

Structural basis for the mechanism of action in glycoside hydrolase family 3 isoprimeverose-producing oligoxyloglucan hydrolase
Tomohiko Matsuzawa; Masahiro Watanabe; Yusuke Nakamichi; Hironaga Akita; Katsuro Yaoi
FEBS Letters, Jun. 2022, Refereed

Crystal structure of metagenomic β-glycosidase MeBglD2 in complex with various saccharides
Tomohiko Matsuzawa; Masahiro Watanabe; Yusuke Nakamichi; Hironaga Akita; Katsuro Yaoi
Applied Microbiology and Biotechnology, Jun. 2022, Refereed

Biosorption of palladium using Enterobacter oligotrophicus CCA6T
Hironaga Akita, Akio Kumagai
Salt and Seawater Science & Technology, Aug. 2021, Refereed, Not invited
Lead

Draft genome sequence of Klebsiella pneumoniae subsp. pneumoniae CCI2 isolated from leaf soil
Hironaga Akita; Yuya Itoiri; Noriyo Takeda; Zen-ichiro Kimura; Hiroyuki Inoue; Akinori Matsushika
Microbiology Resource Announcements, May 2021, Refereed, Not invited
Lead

Application of Pichia kudriavzevii NBRC1279 and NBRC1664 to Simultaneous Saccharification and Fermentation for Bioethanol Production
Hironaga Akita; Tetsuya Goshima; Toshihiro Suzuki; Yuya Itoiri; Zen-ichiro Kimura; Akinori Matsushika
Fermentation, May 2021, Refereed, Not invited
Lead

Preparation of oil palm empty fruit bunch hydrolysate
Hironaga Akita; Mohd Zulkhairi Mohd Yusoff; Shinji Fujimoto
Fermentation, May 2021, Refereed, Not invited
Lead

Paenibacillus glycanilyticus subsp. hiroshimensis subsp. nov., isolated from leaf soil collected in Japan
Hironaga Akita; Yuya Itoiri; Noriyo Takeda; Akinori Matsushika; Zen-ichiro Kimura
Archives of Microbiology, May 2021, Refereed
Lead

Draft genome sequence of Enterobacter oligotrophicus CCA3 isolated from leaf soil
Hironaga Akita; Yuya Itoiri; Noriyo Takeda; Zen-ichiro Kimura; Akinori Matsushika
Microbiology Resource Announcements, Jan. 2021, Refereed
Lead

Draft genome sequence of Enterobacter sp. AS-1, a potential eurytrophic recombination host
Yuki Iwasaki; Yuya Itoiri; Sota Ihara; Hironaga Akita; Mamoru Oshiki; Zen-ichiro Kimura
Journal of Genomics, Jan. 2021, Refereed

Isolation, draft genome sequencing and identification of Enterobacter roggenkampii CCI9
Hironaga Akita; Yuya Itoiri; Noriyo Takeda; Zen-ichiro Kimura; Hiroyuki Inoue; Akinori Matsushika
Journal of Genomics, Jan. 2021, Refereed
Lead

Performance of Burkholderia multivorans CCA53 for ethyl red degradation
Hironaga Akita; Shinji Fujimoto; Keisuke Wada; Noriyo Takeda; Yuki Iwasaki; Tatsuya Fujii; Akinori Matsushika
The Journal of General and Applied Microbiology, Nov. 2020, Refereed
Lead

Characterization of an NAD(P)+-dependent meso-diaminopimelate dehydrogenase from Thermosyntropha lipolytica
Hironaga Akita; Yusuke Nakamichi; Tomotake Morita; Akinori Matsushika
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Oct. 2020, Refereed
Lead

Deinococcus kurensis sp. nov., isolated from pond water collected in Japan
Hironaga Akita; Yuya Itoiri; Sota Ihara; Noriyo Takeda; Akinori Matsushika; Zen-ichiro Kimura
Archives of Microbiology, Sep. 2020, Refereed
Lead

Identification and functional characterization of NAD(P)+‐dependent meso‐diaminopimelate dehydrogenase from Numidum massiliense
Hironaga Akita; Yusuke Nakamichi; Tomotake Morita; Akinori Matsushika
MicrobiologyOpen, Aug. 2020, Refereed
Lead

Application of a pyruvate-producing Escherichia coli strain LAFCPCPt-accBC-aceE: a case study for D-lactate production
Keisuke Wada; Tatsuya Fujii; Hiroyuki Inoue; Hironaga Akita; Tomotake Morita; Akinori Matsushika
Fermentation, Jul. 2020, Refereed

Draft genome sequence of Deinococcus sp. KR-1, a potential strain for palladium-leaching
Hironaga Akita; Yuya Itoiri; Akio Kumagai; Noriyo Takeda; Akinori Matsushika; Mamoru Oshiki; Zen-ichiro Kimura
Journal of Genomics, Feb. 2020, Refereed
Lead

IoGAS1, a GPI-anchored protein derived from Issatchenkia orientalis, confers tolerance of Saccharomyces cerevisiae to multiple acids
Keisuke Wada; Tatsuya Fujii; Hironaga Akita; Akinori Matsushika
Applied Biochemistry and Biotechnology, Nov. 2019, Refereed

Enterobacter oligotrophica sp. nov., a novel oligotroph isolated from leaf soil
Hironaga Akita; Akinori Matsushika; Zen‐ichiro Kimura
MicrobiologyOpen, Sep. 2019, Refereed
Lead

Pseudomonas humi sp. nov., isolated from leaf soil
Hironaga Akita; Zen-ichiro Kimura; Tamotsu Hoshino
Archives of Microbiology, Nov. 2018, Refereed
Lead

Artificial thermostable D-amino acid dehydrogenase: creation and application
Hironaga Akita; Junji Hayashi; Haruhiko Sakuraba; Toshihisa Ohshima
Frontiers in Microbiology, Aug. 2018, Refereed
Lead

Production of acetoin from hydrothermally pretreated oil mesocarp fiber using metabolically engineered Escherichia coli in a bioreactor system
Mohd Zulkhairi Mohd Yusoff; Hironaga Akita; Mohd Ali Hassan; Shinji Fujimoto; Masaru Yoshida; Nobutaka Nakashima; Tamotsu Hoshino
Bioresource Technology, Dec. 2017, Refereed
Corresponding

Identification and characterization of Burkholderia multivorans CCA53
Hironaga Akita; Zen-ichiro Kimura; Mohd Zulkhairi Mohd Yusoff; Nobutaka Nakashima; Tamotsu Hoshino
BMC Research Notes, Dec. 2017, Refereed
Lead

Complete genome sequence of Ureibacillus thermosphaericus A1, a thermophilic Bacillus isolated from compost
Hironaga Akita; Zen-ichiro Kimura; Akinori Matsushika
Genome Announcements, Sep. 2017, Refereed
Lead

Comparison of excess sludge reduction effect of dichlorophenol isomers
Zen-ichiro Kimura; Hironaga Akita
Journal of Pollution Effects & Control, Aug. 2017, Refereed, Not invited

Production of D-lactate using a pyruvate-producing Escherichia coli strain
Hironaga Akita; Nobutaka Nakashima; Tamotsu Hoshino
Bioscience Biotechnology and Biochemistry, Jul. 2017, Refereed
Lead

Structure-based engineering of an artificially generated NADP+-dependent D-amino acid dehydrogenase
Junji Hayashi; Tomonari Seto; Hironaga Akita; Masahiro Watanabe; Tamotsu Hoshino; Kazunari Yoneda; Toshihisa Ohshima; Haruhiko Sakuraba
Applied and Environmental Microbiology, Jun. 2017, Refereed

Draft genome sequence of Pseudomonas sp. strain CCA1, isolated from leaf soil
Hironaga Akita; Zen-ichiro Kimura; Tamotsu Hoshino
Genome Announcements, Dec. 2016, Refereed
Lead

Pyruvate production using engineered Escherichia coli
Hironaga Akita; Nobutaka Nakashima; Tamotsu Hoshino
AMB Express, Dec. 2016, Refereed
Lead

Isolation and characterization of Burkholderia sp. strain CCA53 exhibiting ligninolytic potential
Hironaga Akita; Zen-ichiro Kimura; Mohd Zulkhairi Mohd Yusoff; Nobutaka Nakashima; Tamotsu Hoshino
SpringerPlus, Dec. 2016, Refereed
Lead

Isolation of Pseudomonas sp. strain CCA1 from leaf soil and preliminary characterization its ligninolytic activity
Hironaga Akita; Zen-ichiro Kimura; Mohd Zulkhairi Mohd Yusoff; Tamotsu Hoshino
JSM Biotechnology & Biomedical Engineering, Oct. 2016, Refereed, Not invited
Lead

Draft genome sequence of Burkholderia sp. strain CCA53, isolated from leaf soil
Hironaga Akita; Zen-ichiro Kimura; Mohd Zulkhairi Mohd Yusoff; Nobutaka Nakashima; Tamotsu Hoshino
Genome Announcements, Aug. 2016, Refereed
Lead

Crystal structure of an acetyl esterase complexed with acetate ion provides insights into the catalytic mechanism
Keiko Uechi; Saori Kamachi; Hironaga Akita; Shouhei Mine; Masahiro Watanabe
Biochemical and Biophysical Research Communications, Aug. 2016, Refereed

Characterization of the Kluyveromyces marxianus strain DMB1 YGL157w gene product as a broad specificity NADPH-dependent aldehyde reductase
Hironaga Akita; Masahiro Watanabe; Toshihiro Suzuki; Nobutaka Nakashima; Tamotsu Hoshino
AMB Express, Dec. 2015, Refereed
Lead

Molecular cloning and characterization of two YGL039w genes encoding broad specificity NADPH-dependent aldehyde reductases from Kluyveromyces marxianus strain DMB1
Hironaga Akita; Masahiro Watanabe; Toshihiro Suzuki; Nobutaka Nakashima; Tamotsu Hoshino
FEMS Microbiology Letters, Aug. 2015, Refereed
Lead

Structural insight into the thermostable NADP+-dependent meso-diaminopimelate dehydrogenase from Ureibacillus thermosphaericus
Hironaga Akita; Tomonari Seto; Toshihisa Ohshima; Haruhiko Sakuraba
Acta Crystallographica Section D Biological Crystallography, May 2015, Refereed
Lead

Spectrophotometric assay of D-isoleucine using an artificially created D-amino acid dehydrogenase
Hironaga Akita; Yoshifumi Imaizumi; Hirokazu Suzuki; Katsumi Doi; Toshihisa Ohshima
Biotechnology Letters, Nov. 2014, Refereed
Lead

Bacterial production of isobutanol without expensive reagents
Hironaga Akita; Nobutaka Nakashima; Tamotsu Hoshino
Applied Microbiology and Biotechnology, Oct. 2014, Refereed
Lead

Establishment of a novel gene expression method, BICES (biomass-inducible chromosome-based expression system), and its application to the production of 2,3-butanediol and acetoin
Nobutaka Nakashima; Hironaga Akita; Tamotsu Hoshino
Metabolic Engineering, Sep. 2014, Refereed

Efficient synthesis of D-branched-chain amino acids and their labeled compounds with stable isotopes using D-amino acid dehydrogenase
Hironaga Akita; Hirokazu Suzuki; Katsumi Doi; Toshihisa Ohshima
Applied Microbiology and Biotechnology, Feb. 2014, Refereed
Lead

Creation of a thermostable NADP+-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus strain A1 meso-diaminopimelate dehydrogenase by site-directed mutagenesis
Hironaga Akita; Katsumi Doi; Yutaka Kawarabayasi; Toshihisa Ohshima
Biotechnology Letters, Sep. 2012, Refereed
Lead

Highly stable meso-diaminopimelate dehydrogenase from an Ureibacillus thermosphaericus strain A1 isolated from a Japanese compost: purification, characterization and sequencing
Hironaga Akita; Yasuhiro Fujino; Katsumi Doi; Toshihisa Ohshima
AMB Express, Nov. 2011, Refereed, Not invited
Lead

SDGs の観点を導入した研究リソースの利活用による 探求・学科横断型授業の設計II −考え抜くTBL 実践のためのディスカッション教材の開発−
間田潤; 朝本紘充; 今滝暢子; 秋田紘長; 柴山均; 高橋智輝; 森 健太郎; 松本 真和
工学教育, Jul. 2024, Refereed, Not invited

D-アミノ酸って知っていますか？
秋田紘長
生物工学会誌, May 2024, Refereed, Not invited
Lead

SDGs の観点を導入した研究リソースの利 活用による探求・学科横断型授業の設計- 工学系初年次教育における大人数クラスで の教育効果の検証-
間田潤; 朝本紘充; 今滝暢子; 秋田紘長; 新井健一; 大熊康典; 大坂直樹; 菊地俊紀; 北島雄一郎; 小林奈央樹; 柴山均; 高橋智輝; 髙寄正樹; 三浦慎一郎; 南澤宏明; 森 健太郎; 松本 真和
工学教育, Feb. 2024, Refereed, Not invited

大腸菌を対象とした遺伝子組換え技術の開発と応用
秋田紘長; 中島信孝
科学と工業, Jan. 2023, Refereed, Invited
Lead

バイオ系のキャリアデザイン (インタビュー編)
秋田紘長
生物工学会誌, Nov. 2022, Refereed
Lead

高知県産香酸柑橘ブシュカン果皮の乳酸発酵による利用の試み
堀江祐範; 秋田紘長; 中道優介; 奈良一寛; 高山竜大; 田村吉教
日本食品工学会誌, May 2022, Refereed, Not invited

A simple method for the screening, isolation, and identification of novel bacteria
Hironaga Akita; Zen-ichiro Kimura
Journal of Environmental Biotechnology, Feb. 2022, Refereed, Not invited
Lead

耐熱性NADP+依存性D-アミノ酸脱水素酵素の創製と応用
秋田紘長
D-アミノ酸学会誌, Apr. 2019, Not refereed, Invited
Lead

大腸菌の炭素カタボライト抑制解除
秋田紘長
生物工学会誌, May 2016, Refereed, Not invited
Lead

耐熱性人工NADP＋依存性D-アミノ酸脱水素酵素：創製と応用
秋田紘長; 櫻庭春彦; 大島敏久
ビタミン, Jan. 2016, Refereed, Not invited
Lead

耐熱性D-アミノ酸脱水素酵素のタンパク質工学的創製と利用
秋田紘長; 櫻庭春彦; 大島敏久
生化学, Oct. 2015, Refereed, Not invited

5. 部位特異変異法による耐熱性NADP+依存性D-アミノ酸脱水素酵素の創製
大島敏久; 秋田紘長; 土居克実
ビタミン, Aug. 2012, Refereed, Not invited

腐食が発生していない金属を対象とした菌叢解析
秋田紘長
第57回 日本大学生産工学部学術講演会, Dec. 2024, Not invited

木質系バイオマスを原料に利用するバイオ燃料の発酵生産プロセスの開発
秋田紘長
第56回 日本大学生産工学部学術講演会, Dec. 2023, Not invited

細菌による金属腐食を未然に防ぐためのガイドラインの策定 –腐食が発生していない金属から採取したバイオフィルムを対象とした菌叢解析–
秋田紘長; 新藤義稀; 木村善一郎
2023年度日本海水学会第74年会, Jun. 2023

貧栄養耐性細菌Enterobacter oligotrophicus CCA6Tを利用したパラジウムの回収
秋田紘長
2023年度日本海水学会第74年会, Jun. 2023, Not invited

木質系バイオマスを原料に利用するアルコール・有機酸の発酵生産プロセスの開発 (受賞講演)
秋田紘長
環境バイオテクノロジー学会2022年度大会, Nov. 2022, Invited

微生物に起因する金属腐食メカニズムの解明を可能とする評価基盤技術の開発
秋田紘長
第34回助成研究発表会 ソルト・サイエンス研究財団, Jul. 2022, Not invited

新しい酵素化学的性質を有するmeso-ジアミノピメリン酸 脱水素酵素の発見と D-アミノ酸合成への応用 (受賞講演)
秋田紘長
酵素工学研究会第86回講演会, Nov. 2021, Invited

Burkholderia multivorans CCA53株の色素分解への応用
秋田紘長, 和田圭介, 藤井達也, 松鹿昭則
環境バイオテクノロジー学会2019年度大会, Jun. 2019, Not invited

Kluyveromyces marxianus DMB1株由来のNADPH依存性アルデヒド還元酵素の機能解析
秋田紘長, 星野保, 松鹿昭則
酵素工学研究会第 80回講演会, Nov. 2018, Not invited

Burkholderia multivorans CCA53株の単離とリグニン分解能の解析
秋田紘長; 木村善一郎; 星野保; 松鹿昭則
環境バイオテクノロジー学会2018年度大会, Jun. 2018, Not invited

D-アミノ酸生産プロセスの開発
秋田紘長
産総研中国センターシンポジウム in 岡山, Feb. 2018, Not invited

D-アミノ酸生産プロセスの開発
秋田紘長
平成29年度 産総研 材料・化学シンポジウム, Feb. 2018, Not invited

ピルビン酸高生産大腸菌を利用したD-乳酸の生産
秋田紘長; 中島信孝; 星野保
第69回日本生物工学会大会, Sep. 2017, Not invited

Structural-based engineering of an artificially created NADP-dependent D-amino acid dehydrogenase
Toshihisa Ohshima; Hironaga Akita; Junji Hayashi; Haruhiko Sakuraba
The 3rd International Conference of D-Amino Acid Research, Aug. 2017, Not invited

Creation and application of a thermostable artificial NADP+-dependent D-amino acid dehydrogenase (Invited lecture)
Hironaga Akita
The 3rd International Conference of D-Amino Acid Research, Jul. 2017, Invited

人工NADP-依存性D-アミノ酸脱水素酵素の構造情報に基づく機能改変
大島敏久; 林順司; 秋田紘長; 櫻庭春彦
2017年度 酵素補酵素研究会, Jun. 2017, Not invited

Novel genetic tools for manipulating Escherichia coli (Invited lecture)
Nobutaka Nakashima; Yuya Nakamura; Yuta Kino; Hironaga Akita; Tamotsu Hoshino
KMB 2017 Annual Meeting & International Symposium, Jun. 2017, Invited

Transformation of oil palm biomass into value added product
Mohd Zulkhairi Mohd Yusoff; Hironaga Akita; Nobutaka Nakashima; Shinji Fujimoto; Mohd Ali Hassan; Tamotsu Hoshino
九工大・マレーシアプトラ大学国際合同シンポジウム, Dec. 2016, Not invited

ピルビン酸高生産大腸菌を利用したピルビン酸の生産
秋田紘長; 中島信孝; 星野保
第68回日本生物工学会大会, Sep. 2016, Not invited

耐熱性NADP+依存性D-アミノ酸脱水素酵素の創製
秋田紘長; 櫻庭春彦; 大島敏久
第12回D-アミノ酸学会学術講演会, Sep. 2016, Not invited

Utilization of Oil Palm Biomass for Acetoin Production using Engineered Escherichia coli
Mohd Zulkhairi Mohd Yusoff; Hironaga Akita; Nobutaka Nakashima; Tamotsu Hoshino
第68回日本生物工学会大会, Sep. 2016, Not invited

大腸菌における遺伝子発現の低コスト化と生育必須遺伝子の操作方法
中島信孝; 秋田紘長; 星野保
第67回日本生物工学会大会, Oct. 2015, Not invited

キシロース誘導型外来遺伝子発現システムを利用したイソブタノールの生産
秋田紘長; 中島信孝; 星野保
第67回日本生物工学会大会, Oct. 2015, Not invited

Thermostable NADP-dependent D-amino acid dehydrogenase created by site-directed mutation: characteristics and application (Invited lecture)
Toshihisa Ohshima; Hironaga Akita; Katsumi Doi; Haruhiko Sakuraba
18th Japanese-German Workshop Enzyme Technology, Sep. 2015, Invited

蛋白研ビームラインを利用したAIST-ISCの研究成果について
渡邊真宏; 蒲池沙織; 秋田紘長; 上地敬子; 峯昇平
大阪大学蛋白質研究所セミナー, Aug. 2015, Not invited

Thermostable NADP-dependent D-amino acid dehydrogenase: Creation from meso-diaminopimelate dehydrogenase by site-directed mutagenesis and application
Toshihisa Ohshima; Hironaga Akita; Katsumi Doi; Hirokazu Suzuki
Enzyme Engineering XXII, Sep. 2013, Not invited

耐熱性NADP依存性D-アミノ酸脱水素酵素の構造解析
秋田紘長, 土居克実, 大島敏久, 櫻庭春彦
日本農芸化学会関西・中四国・西日本支部合同大会(第481回講演会), Sep. 2013, Not invited

Efficient synthesis and stable isotope-labeling of D-branched-chain amino acids using thermostable D-amino acid dehydrogenase
Hironaga Akita; Hirokazu Suzuki; Katsumi Doi; Toshihisa Ohshima
Thermophiles 2013 12th International Meeting, Sep. 2013, Not invited

変異型のNADP依存性D-アミノ酸脱水素酵素を用いるD-アミノ酸の分光学的分析法の開発
今泉吉史, 秋田紘長, 牟田口祐太, 清水泰博, 大島敏久
日本農芸化学会2013年度仙台大会, Mar. 2013, Not invited

Creation of a thermostable NADP-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus
Hironaga Akita; Katsumi Doi; Yutaka Kawarabayashi; Toshihisa Ohshima
9th International Congress on Extremophiles, Sep. 2012, Not invited

部位特異的変異法を用いた耐熱性NADP依存性D-アミノ酸脱水素酵素の創製と機能解析
秋田紘長; 土居克実; 大島敏久
2012年度 酵素補酵素研究会, Jul. 2012, Not invited

部位特異的変異法による耐熱性NADP依存性D-アミノ酸脱水素酵素の創製
大島敏久; 秋田紘長; 土居克実
第428回ビタミンB研究協議会, Jun. 2012, Not invited

耐熱性NADP依存性D-アミノ酸脱水素酵素の創製と機能解析
秋田紘長; 土居克実; 大島敏久
日本生化学会九州支部例会(福岡大会), May 2012, Not invited

好熱菌Ureibacillus thermosphaericusの耐熱性NADP依存性meso-ジアミノピメリン酸脱水素酵素の探索および機能解析
秋田紘長; 土居克実; 大島敏久
平成23年度 日本農芸化学会西日本支部・中四国支部合同大会, Sep. 2011, Not invited

好熱菌Ureibacillus thermosphaericusの耐熱性NADP依存性meso-ジアミノピメリン酸脱水素酵素の発見と機能解析
秋田紘長; 土居克実; 大島敏久
日本農芸化学会2011年度大会, Mar. 2011, Not invited

好熱菌Ureibacillus thermosphaericus由来のNADP依存性 meso-ジアミノピメリン酸脱水素酵素の機能解析
秋田紘長; 土居克実; 大島敏久
化学関連支部合同九州大会, Jul. 2010, Not invited

励起した気相の液相への微細化導入による酸素種活性種の生成促進
秋田紘長; 松本真和; 尾上薫
第10回化学工学会学生発表会 (群馬大会), Mar. 2008, Not invited

Jun. 2024 - Present

Apr. 2024 - Present

Nov. 2023 - Present

Sep. 2023 - Present

Apr. 2023 - Present

Apr. 2023 - Present

自然生態学
Apr. 2021 - Aug. 2021
Kure National College of Technology

Japanese Society of Enzyme Engineering

Japan Society for Environmental Biotechnology

The Society for Biotechnology, Japan

D-AMINO ACID RESEARCH SOCIETY

日本海水学会

BTCK01000001–BTCK01000158：Draft genome sequence of Paenibacillus sp. CCS19
Hironaga Akita; Yoshiki Shinto; Zen-ichiro Kimura
Jun. 2023, Database

BTCL01000001–BTCL01000090：Draft genome sequence of Paenibacillus glycanilyticus subsp. hiroshimensis CCS26
Hironaga Akita; Yoshiki Shinto; Zen-ichiro Kimura
Jun. 2023, Database

BNJO01000001–BNJO01000078：Draft genome sequence of Klebsiella pneumoniae subsp. pneumoniae CCI2
Akita H; Itoiri Y; Takeda N; Kimura ZI; Inoue H; Matsushika A
Jun. 2021, Database

BNJN01000001-BNJN01000029：Draft genome sequence of Enterobacter oligotrophicus CCA3
Akita H; Itoiri Y; Takeda N; Kimura ZI; Inoue H; Matsushika A
May 2021, Database

BNJP01000001–BNJP01000049：Draft genome sequence of Paenibacillus glycanilyticus subsp. hiroshimensis
Akita H; Itoiri Y; Takeda N; Matsushika A; Kimura ZI
May 2021, Database

HUT-8145T = KCTC 43270T：Paenibacillus glycanilyticus subsp. hiroshimensis subsp. nov.
Akita H; Itoiri Y; Takeda N; Matsushika A; Kimura ZI
May 2021, Others

BMBZ01000001–BMBZ01000018：Draft genome sequence of Enterobacter sp. AS-1
Iwasaki Y; Itoiri Y; Ihara S; Akita H; Oshiki M; Kimura ZI
Jan. 2021

BLPJ01000001–BLPJ01000028：Draft genome sequence of Enterobacter roggenkampii CCI9
Akita H, Itoiri Y, Kimura ZI
Sep. 2020, Database

HUT-8138T = KCTC 33977T：Deinococcus kurensis sp. nov.
Akita H, Itoiri Y, Ihara S, Takeda N, Matsushika A, Kimura ZI
Feb. 2020, Others

BLBE01000001–BLBE01000007：Draft genome sequence of Deinococcus kurensis KR-1
Akita H, Itoiri Y, Kimura ZI
Nov. 2019, Database

AP019007：Complete genome sequence of Enterobacter oligotrophicus CCA6
Akita H
Oct. 2019, Database

BDGS01000001–BDGS01000024：Draft genome sequence of Pseudomonas humi CCA1
Akita H
Sep. 2019, Database

HUT-8142T = KCTC 62525T：Enterobacter oligotrophica sp. nov.
Akita H, Matsushika A, Kimura ZI
May 2019, Others

HUT8136T =TBRC8616T：Pseudomonas humi sp. nov.
Akita H, Kimura ZI, Hoshino T
Nov. 2018, Others

AP018335：Complete genome sequence of Ureibacillus thermosphaericus A1
Akita H
Jun. 2017, Database

BDDJ01000001–BDDJ01000004：Draft genome sequence of Burkholderia multivorans CCA53
Akita H
May 2016, Database

3WYC：Structure of a meso-diaminopimelate dehydrogenase in complex with NADP
Sakuraba H, Akita H, Ohshima T
May 2015, Database

3WYB：Structure of a meso-diaminopimelate dehydrogenase
Sakuraba H, Akita H, Ohshima T
May 2015, Database

Enterobacter oligotrophicus CCA6Tを利用するD-アラニン発酵法の開発
公益財団法人 発酵研究所, 一般研究助成, Apr. 2024 - Mar. 2026
秋田紘長

微生物誘起腐食を未然に防ぐガイドラインの策定
公益財団法人 ソルトサイエンス研究財団 2024年度研究助成, Apr. 2024 - Mar. 2025

皮膚バリア機能を促進するD-アミノ酸の酵素合成法の開発
KOSÉ Cosmetology Research Foudation, 2023年度コスメトロジー研究助成, Dec. 2023 - Nov. 2024
秋田紘長

貧栄養耐性細菌を利用した都市鉱山からのパラジウム回収法の開発
The Sumitomo Foundation, 環境研究助成, Nov. 2023 - Nov. 2024
秋田紘長

微生物に起因する金属腐食メカニズムの解明を可能とする評価基盤技術の開発
The Salt Science Research Foundation, General Research, Apr. 2021 - Mar. 2022
秋田紘長

貧栄養耐性細菌を利用したD-アミノ酸発酵法の開発
Japan Society for the Promotion of Science, KAKENHI, Apr. 2019 - Mar. 2022
Akita Hironaga

D-アミノ酸の高度利用に関する研究
国内化学メーカー, 資金提供型共同研究, Apr. 2018 - Mar. 2022
秋田紘長

非可食バイオマスの直接発酵を可能とする宿主微生物の開発
Japan Society for the Promotion of Science, Grant-in-Aid for Encouragement of Young Scientists (B) (KAKENHI), Apr. 2016 - Mar. 2018
Akita Hironaga

生物多様性保全のためのパーム油産業によるグリーン経済の推進プロジェクト
Japan Science and Technology Agency (JST), SATREPS, Apr. 2012 - Mar. 2017
Shirai Yoshito

Creation and application of thermostable d-amino acid dehydrogenase by protein engineering
Japan Society for the Promotion of Science, KAKENHI, Apr. 2013 - Mar. 2014
Akita Hironaga

特許EP3666894, 特願18844724.7, D-TYPE AMINO ACID DEHYDROGENASE
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田 友岳, (株) クレハ

特許EP3666893, 特願18844470.7, D-TYPE AMINO ACID DEHYDROGENASE
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田 友岳, (株) クレハ

特許US11098288, 特願16/637444, D-TYPE AMINO ACID DEHYDROGENASE
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田 友岳, (株) クレハ

特許6853549, 特開2017-108740, 特願2016-242578, 改変型meso-ジアミノピメリン酸脱水素酵素
秋田紘長, 星野保, 大島敏久, 櫻庭春彦, 渡邊真宏

特許US10927354, 特願16/637419, D-TYPE AMINO ACID DEHYDROGENASE
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田 友岳, (株) クレハ

特許CN111133105, 特願201880050244.7, D-TYPE AMINO ACID DEHYDROGENASE
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田 友岳, (株) クレハ

特開CN111051508, D型アミノ酸脱水素酵素
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田友岳, (株)クレハ

特許6675520, 特願2019-535715, D型アミノ酸脱水素酵素
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田 友岳, (株) クレハ

特許6675519, 特願2019-535714, D型アミノ酸脱水素酵素
秋田紘長, 渡邉真宏, 中道優介, 松鹿昭則, 森田 友岳, (株) クレハ

特許6621318, 特開2017-108646, 大腸菌変異株及びこれを用いたピルビン酸の製造方法
秋田紘長, 中島信孝, 星野保

特開2019-022462, 特願2017-142847, 新規微生物
秋田紘長, 木村善一郎, 松鹿昭則

小学生向け理科教室「夢・化学-21」
organizing_member
日本大学生産工学部, 03 Nov. 2024 - 03 Nov. 2024

スーパーサイエンスハイスクール (西条農業高校) 指導助言者
advisor
Apr. 2018 - 31 Mar. 2023

インターンシップ生 (呉工業高等専門学校) 指導教官
advisor
Jun. 2021 - Aug. 2021

インターンシップ生 (呉工業高等専門学校) 指導教官
advisor
May 2019 - Aug. 2019

博士研究員 (Universiti Putra Malaysia) 指導教官
advisor
Oct. 2015 - Mar. 2017

テレビ番組制作協力 (ナゼそこ？)
テレビ東京, Aug. 2024, Media report

テレビ番組制作協力 (ナゼそこ？)
テレビ東京, Jul. 2024, Media report

期待が集まる D-アミノ酸の新生産法を開発！〜酵素の自在設計で D-アミノ酸を生産〜
産総研 WEEKLY, 23 Jun. 2017, Internet

Special Issue: Metabolic Engineering of Yeast for the Production of Fuels and Chemicals
Others
18 Nov. 2024 - Present

Special Issue: Bioconversion of Biomass for Effective Production of Biofuels as Well as Biobased Chemicals and Materials
Others
Aug. 2023 - Present

生物工学会誌 100年史ワーキンググループ
Academic research planning
公益社団法人 日本生物工学会, Oct. 2020 - Oct. 2022

公認ファシリテーター (有資格)
Sep. 2023 - Present

エックス線作業主任者 (有資格)
Feb. 2017 - Present

危険物取扱者甲種 (有資格)
Oct. 2016 - Present

特定化学物質及び四アルキル鉛等作業主任者 (有資格)
Feb. 2016 - Present

有機溶剤作業主任者 (有資格)
Feb. 2016 - Present

衛生工学衛生管理者 (有資格)
Feb. 2016 - Present

生産工学部教育貢献賞 グループ (生産工学とSDGs)
Feb. 2024

感謝状 (広島県立西条農業高校)
Mar. 2022