Nucleus Accumbens

Insular Cortex

Incurable nerve disorders

Neuropathic pain

Neuropharmacology

GABA

Dopamine

Oral dyskinesia

Life sciences, Oral medicine, Functional Basic Odontology

Life sciences, Neuroscience - general, Nerve Chemistry/Nerve Pharmacology

Life sciences, Neuroscience - general, General Neuroscience

Life sciences, Pharmacology, Neuropharmacology

Life sciences, Pharmacology, General Pharmacology

Apr. 2016 - Mar. 2021
Nihon University School of Dentistry, Department of Pharmacology, Project Professor

Apr. 1999 - Mar. 2016
Nihon University School of Dentistry, Department of Pharmacology, Professor

Sep. 2011 - Aug. 2014
Nihon University School of Dentistry, Dean

Apr. 1989 - Mar. 1999
Nihon University School of Dentistry, Department of Pharmacology, Associate Professor

Apr. 1986 - Mar. 1989
Nihon University School of Dentistry, Department of Pharmacology, Assistant Professor

Dec. 1983 - Mar. 1986
Nihon University School of Dentistry, Department of Pharmacology, Lecturer

Apr. 1979 - Nov. 1983
Nihon University School of Dentistry, Department of Pharmacology, Research Assistant

Apr. 1975 - Mar. 1979
Nihon University, Graduate School, Division of Dental Research, Pharmacology

Apr. 1969 - Mar. 1975
Nihon University, School of Dentistry, Dentistry

Apr. 2016 - Present
名誉会員, 日本薬理学会

Oct. 1991 - Present
評議員, 歯科基礎医学会

Oct. 1991 - Present
名誉会員, 歯科基礎医学会

Jan. 1990 - Present
評議員, 日本神経精神薬理学会

Jan. 1990 - Present
功労会員, 日本神経精神薬理学会

Feb. 2000 - Apr. 2016
評議員, 日本歯科薬物療法学会

Apr. 2014 - Mar. 2016
研究推進委員会委員, 日本薬理学会

Jan. 2000 - Mar. 2016
評議員, 日本歯科心身医学会

Apr. 1990 - Mar. 2016
評議員, 日本薬理学会

Apr. 2012 - Mar. 2014
広報委員会委員, 日本薬理学会

Apr. 2010 - Mar. 2012
理事, 日本薬理学会

Apr. 2009 - Mar. 2012
理事, 歯科基礎医学会

Apr. 2009 - Mar. 2012
評議員, 歯科基礎医学会

Apr. 2004 - Mar. 2012
企画教育委員会委員, 日本薬理学会

Jan. 2008 - Dec. 2011
学術委員, 日本歯科薬物療法学会

Phase-dependent activity of neurons in the rostral part of the thalamic reticular nucleus with saccharin intake in a cue-guided lever manipulation task
Ryuhei Aoki; Risako Kato; Satoshi Fujita; Jun Shimada; Noriaki Koshikawa; Masayuki Kobayashi
BRAIN RESEARCH, Mar. 2017, Refereed, Not invited

OPIOID SUBTYPE- AND CELL-TYPE-DEPENDENT REGULATION OF INHIBITORY SYNAPTIC TRANSMISSION IN THE RAT INSULAR CORTEX
Eiko Yokota; Yuko Koyanagi; Kiyofumi Yamamoto; Yoshiyuki Oi; Noriaki Koshikawa; Masayuki Kobayashi
NEUROSCIENCE, Dec. 2016, Refereed, Not invited

Spike Timing Rigidity Is Maintained in Bursting Neurons under Pentobarbital-Induced Anesthetic Conditions
Risako Kato; Masanori Yamanaka; Eiko Yokota; Noriaki Koshikawa; Masayuki Kobayashi
FRONTIERS IN NEURAL CIRCUITS, Nov. 2016, Refereed, Not invited

Sequential Changes in Cortical Excitation during Orthodontic Treatment
E. Horinuki; K. Yamamoto; N. Shimizu; N. Koshikawa; M. Kobayashi
JOURNAL OF DENTAL RESEARCH, Jul. 2016, Refereed, Not invited

Cytoarchitecture-Dependent Decrease in Propagation Velocity of Cortical Spreading Depression in the Rat Insular Cortex Revealed by Optical Imaging
Satoshi Fujita; Naoko Mizoguchi; Ryuhei Aoki; Yilong Cui; Noriaki Koshikawa; Masayuki Kobayashi
CEREBRAL CORTEX, Apr. 2016, Refereed, Not invited

Distinct Excitation to Pulpal Stimuli between Somatosensory and Insular Cortices
H. Nakamura; T. Shirakawa; N. Koshikawa; M. Kobayashi
JOURNAL OF DENTAL RESEARCH, Feb. 2016, Refereed, Not invited

Orthodontic Force Facilitates Cortical Responses to Periodontal Stimulation
E. Horinuki; M. Shinoda; N. Shimizu; N. Koshikawa; M. Kobayashi
JOURNAL OF DENTAL RESEARCH, Aug. 2015, Refereed, Not invited

Spatiotemporal profiles of dental pulp nociception in rat cerebral cortex: An optical imaging study
Hiroko Nakamura; Risako Kato; Tetsuo Shirakawa; Noriaki Koshikawa; Masayuki Kobayashi
Journal of Comparative Neurology, Jun. 2015, Refereed, Not invited

Accumbal alpha-adrenoceptors, but not beta-adrenoceptors, regulate behaviour that is mediated by reserpine-sensitive storage vesicles
Michel M. M. Verheij; Tadashi Saigusa; Noriaki Koshikawa; Alexander R. Cools
BEHAVIOURAL PHARMACOLOGY, Feb. 2015, Refereed, Invited

Simultaneous activation of the alpha(1A)-, alpha(1B)- and alpha(1D)-adrenoceptor subtypes in the nucleus accumbens reduces accumbal dopamine efflux in freely moving rats
Yuri Aono; Hiroko Taguchi; Tadashi Saigusa; Takuya Uchida; Koji Takada; Hatakazu Takiguchi; Tetsuo Shirakawa; Noriyoshi Shimizu; Noriaki Koshikawa; Alexander R. Cools
BEHAVIOURAL PHARMACOLOGY, Feb. 2015, Refereed, Invited

Investigating complex basal ganglia circuitry in the regulation of motor behaviour, with particular focus on orofacial movement
Hiroko Ikeda; Kazunori Adachi; Satoshi Fujita; Katsunori Tomiyama; Tadashi Saigusa; Masayuki Kobayashi; Noriaki Koshikawa; John L. Waddington
BEHAVIOURAL PHARMACOLOGY, Feb. 2015, Refereed, Invited

PRESYNAPTIC CELL TYPE-DEPENDENT REGULATION OF GABAERGIC SYNAPTIC TRANSMISSION BY NITRIC OXIDE IN RAT INSULAR CORTEX
K. Yamamoto; H. Takei; Y. Koyanagi; N. Koshikawa; M. Kobayashi
NEUROSCIENCE, Jan. 2015, Refereed, Not invited

Fast-spiking Cell to Pyramidal Cell Connections Are the Most Sensitive to Propofol-induced Facilitation of GABAergic Currents in Rat Insular Cortex
Yuko Koyanagi; Yoshiyuki Oi; Kiyofumi Yamamoto; Noriaki Koshikawa; Masayuki Kobayashi
ANESTHESIOLOGY, Jul. 2014, Refereed, Not invited

ACCUMBAL CORE: ESSENTIAL LINK IN FEED-FORWARD SPIRALING STRIATO-NIGRO-STRIATAL IN SERIES CONNECTED LOOP
H. Ikeda; N. Koshikawa; A. R. Cools
NEUROSCIENCE, Nov. 2013, Refereed, Not invited

Reciprocal regulation of inhibitory synaptic transmission by nicotinic and muscarinic receptors in rat nucleus accumbens shell
Kiyofumi Yamamoto; Katsuko Ebihara; Noriaki Koshikawa; Masayuki Kobayashi
Journal of Physiology, Nov. 2013, Refereed, Not invited

PHENOTYPIC CHARACTERIZATION OF OROFACIAL MOVEMENT TOPOGRAPHY IN MUTANTS WITH DISRUPTION OF AMINO ACID MECHANISMS: GLUTAMATE N2A/B/D [GLUR epsilon 1/2/4] SUBTYPES AND THE GABA SYNTHESIZING ENZYME GAD65
K. Tomiyama; R. Kato; Y. Hara; M. Kobayashi; M. Mishina; Y. Yanagawa; A. Kinsella; N. Koshikawa; J. L. Waddington
NEUROSCIENCE, Oct. 2013, Refereed, Not invited

Functional neuroimaging of aversive taste-related areas in the alert rat revealed by positron emission tomography
Masayuki Kobayashi; Yilong Cui; Takeo Sako; Tetsuya Sasabe; Naoko Mizoguchi; Kiyofumi Yamamoto; Yasuhiro Wada; Yosky Kataoka; Noriaki Koshikawa
JOURNAL OF NEUROSCIENCE RESEARCH, Oct. 2013, Refereed, Not invited

Synergistic, but not separate, stimulation of accumbal beta(1)- and beta(2)-adrenoceptors alters the accumbal dopamine efflux in freely moving rats
Yuri Aono; Tadashi Saigusa; Hiroko Taguchi; Takuya Uchida; Koji Takada; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Sep. 2013, Refereed, Not invited

Apomorphine-induced modulation of neural activities in the ventrolateral striatum of rats
Satoshi Fujita; Risako Kato; Yilong Cui; Masanori Terakado; Kurando Suga; Noriaki Koshikawa; Masayuki Kobayashi
SYNAPSE, Jul. 2013, Refereed, Not invited

SPIRALING DOPAMINERGIC CIRCUITRY FROM THE VENTRAL STRIATUM TO DORSAL STRIATUM IS AN EFFECTIVE FEED-FORWARD LOOP
H. Ikeda; T. Saigusa; J. Kamei; N. Koshikawa; A. R. Cools
NEUROSCIENCE, Jun. 2013, Refereed, Not invited

Anatomical and electrophysiological mechanisms for asymmetrical excitatory propagation in the rat insular cortex: In vivo optical imaging and whole-cell patch-clamp studies
Kazunori Adachi; Satoshi Fujita; Atsushi Yoshida; Hiroshi Sakagami; Noriaki Koshikawa; Masayuki Kobayashi
JOURNAL OF COMPARATIVE NEUROLOGY, May 2013, Refereed, Not invited

Cholinergic interneurons suppress action potential initiation of medium spiny neurons in rat nucleus accumbens shell
K. Ebihara; K. Yamamoto; K. Ueda; N. Koshikawa; M. Kobayashi
Neuroscience, Apr. 2013, Refereed, Not invited

Working Mechanism Underlying the Reduction of the Behavioral and Accumbal Dopamine Response to Cocaine by alpha-1-Adrenoceptor Antagonists
Michel M. M. Verheij; Tadashi Saigusa; Noriaki Koshikawa; Alexander R. Cools
NEUROPSYCHOPHARMACOLOGY, Feb. 2013, Refereed, Not invited

Nucleus Accumbens and Dopamine-Mediated Turning Behavior of the Rat: Role of Accumbal Non-dopaminergic Receptors
Hiroko Ikeda; Junzo Kamei; Noriaki Koshikawa; Alexander R. Cools
JOURNAL OF PHARMACOLOGICAL SCIENCES, Nov. 2012, Refereed, Invited

The alpha(1)-, but not alpha(2)-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats
Tadashi Saigusa; Yuri Aono; Takuya Uchida; Koji Takada; Michel M. M. Verheij; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Aug. 2012, Refereed, Not invited

Constitutive and Conditional Mutant Mouse Models for Understanding Dopaminergic Regulation of Orofacial Movements: Emerging Insights and Challenges
Katsunori Tomiyama; John Drago; John L. Waddington; Noriaki Koshikawa
JOURNAL OF PHARMACOLOGICAL SCIENCES, Aug. 2012, Refereed, Invited

Disruption of programmed masticatory movements in unilateral MPTP-treated monkeys as a model of jaw movement abnormality in Parkinson's disease
Kazunori Adachi; Masayuki Kobayashi; Toshiyuki Kawasaki; Chihiro Yokoyama; John L. Waddington; Hiroshi Sakagami; Hirotaka Onoe; Noriaki Koshikawa
JOURNAL OF NEURAL TRANSMISSION, Aug. 2012, Refereed, Not invited

Histaminergic effects on the frequency of repetitive spike firing in rat insular cortex
Hiroki Takei; Liqiu Song; Katsuko Ebihara; Tetsuo Shirakawa; Noriaki Koshikawa; Masayuki Kobayashi
NEUROSCIENCE LETTERS, Jun. 2012, Refereed, Not invited

SPATIOTEMPORAL PROFILES OF TRANSCALLOSAL CONNECTIONS IN RAT INSULAR CORTEX REVEALED BY IN VIVO OPTICAL IMAGING
S. Fujita; T. Kitayama; N. Mizoguchi; Y. Oi; N. Koshikawa; M. Kobayashi
NEUROSCIENCE, Mar. 2012, Refereed, Not invited

Kinetics of GABA(B) autoreceptor-mediated suppression of GABA release in rat insular cortex
Masayuki Kobayashi; Hiroki Takei; Kiyofumi Yamamoto; Hiroshige Hatanaka; Noriaki Koshikawa
JOURNAL OF NEUROPHYSIOLOGY, Mar. 2012, Refereed, Not invited

In vivo neurochemical evidence that newly synthesised GABA activates GABA(B), but not GABA(A), receptors on dopaminergic nerve endings in the nucleus accumbens of freely moving rats
Tadashi Saigusa; Yuri Aono; Reiko Sekino; Takuya Uchida; Koji Takada; Yoshiyuki Oi; Noriaki Koshikawa; Alexander R. Cools
NEUROPHARMACOLOGY, Feb. 2012, Refereed, Not invited

D-2-like dopamine receptors differentially regulate unitary IPSCs depending on presynaptic GABAergic neuron subtypes in rat nucleus accumbens shell
Shuntaro Kohnomi; Noriaki Koshikawa; Masayuki Kobayashi
JOURNAL OF NEUROPHYSIOLOGY, Jan. 2012, Refereed, Not invited

GABA(B) RECEPTORS ACCENTUATE NEURAL EXCITATION CONTRAST IN RAT INSULAR CORTEX
S. Fujita; N. Koshikawa; M. Kobayashi
NEUROSCIENCE, Dec. 2011, Refereed, Not invited

Spatiotemporal dynamics of long-term potentiation in rat insular cortex revealed by optical imaging
Naoko Mizoguchi; Satoshi Fujita; Noriaki Koshikawa; Masayuki Kobayashi
NEUROBIOLOGY OF LEARNING AND MEMORY, Oct. 2011, Refereed, Not invited

Phenotypic Disruption to Orofacial Movement Topography in Conditional Mutants With Generalized CamKIIa/Cre D1Tox Versus Striatal-Specific DARPP-32/Cre D1Tox Ablation of D1 Dopamine Receptor-Expressing Cells
Katsunori Tomiyama; Hyun Ah Kim; Anthony Kinsella; Michelle E. Ehrlich; Guenter Schuetz; Noriaki Koshikawa; Andrew J. Lawrence; John L. Waddington; John Drago
SYNAPSE, Sep. 2011, Refereed, Not invited

Dopamine D-1-like receptors play only a minor role in the increase of striatal dopamine induced by striatally applied SKF38393
Reiko Sekino; Tadashi Saigusa; Yuri Aono; Takuya Uchida; Koji Takada; Yoshiyuki Oi; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Dec. 2010, Refereed, Not invited

Morphine Modulation of Thrombospondin Levels in Astrocytes and Its Implications for Neurite Outgrowth and Synapse Formation
Hiroko Ikeda; Mayumi Miyatake; Noriaki Koshikawa; Kuniyasu Ochiai; Kiyoshi Yamada; Alexi Kiss; Maureen J. Donlin; W. Michael Panneton; James D. Churchill; Michael Green; Akbar M. Siddiqui; Andrew L. Leinweber; Nicholas R. Crews; Lubov A. Ezerskiy; Victoria R. Rendell; Mariana M. Belcheva; Carmine J. Coscia
JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2010, Refereed, Not invited

INSULIN FACILITATES REPETITIVE SPIKE FIRING IN RAT INSULAR CORTEX VIA PHOSPHOINOSITIDE 3-KINASE BUT NOT MITOGEN ACTIVATED PROTEIN KINASE CASCADE
H. Takei; S. Fujita; T. Shirakawa; N. Koshikawa; M. Kobayashi
NEUROSCIENCE, Nov. 2010, Refereed, Not invited

Postsynaptic Cell Type-Dependent Cholinergic Regulation of GABAergic Synaptic Transmission in Rat Insular Cortex
Kiyofumi Yamamoto; Yuko Koyanagi; Noriaki Koshikawa; Masayuki Kobayashi
JOURNAL OF NEUROPHYSIOLOGY, Oct. 2010, Refereed, Not invited

Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity
Kazunori Adachi; Kohei Shimizu; James W. Hu; Ikuko Suzuki; Hiroshi Sakagami; Noriaki Koshikawa; Barry J. Sessle; Masamichi Shinoda; Makiko Miyamoto; Kuniya Honda; Koichi Iwata
MOLECULAR PAIN, Sep. 2010, Refereed, Not invited

Orofacial Movements in Phospholipase C-Related Catalytically Inactive Protein-1/2 Double Knockout Mice: Effect of the GABAergic Agent Diazepam and the D-1 Dopamine Receptor Agonist SKF 83959
Katsunori Tomiyama; Liqiu Song; Masayuki Kobayashi; Anthony Kinsella; Takashi Kanematsu; Masato Hirata; Noriaki Koshikawa; John L. Waddington
SYNAPSE, Sep. 2010, Refereed, Not invited

Presynaptic Interneuron Subtype- and Age-Dependent Modulation of GABAergic Synaptic Transmission by beta-Adrenoceptors in Rat Insular Cortex
Yuko Koyanagi; Kiyofumi Yamamoto; Yoshiyuki Oi; Noriaki Koshikawa; Masayuki Kobayashi
JOURNAL OF NEUROPHYSIOLOGY, May 2010, Refereed, Not invited

Assessment of jaw movements by magnetic sensor in relation to topographies of orofacial behaviour in freely moving rats: Studies with the dopamine D-1-like receptor agonists SKF 83822 vs SKF 83959
Satoshi Fujita; Motori Kiguchi; Masayuki Kobayashi; Anthony Kinsella; Noriaki Koshikawa; John L. Waddington
EUROPEAN JOURNAL OF PHARMACOLOGY, Apr. 2010, Refereed, Not invited

DIFFERENTIAL ROLE OF GABA(A) AND GABA(B) RECEPTORS IN TWO DISTINCT OUTPUT STATIONS OF THE RAT STRIATUM: STUDIES ON THE SUBSTANTIA NIGRA PARS RETICULATA AND THE GLOBUS PALLIDUS
H. Ikeda; A. Kotani; N. Koshikawa; A. R. Cools
NEUROSCIENCE, Apr. 2010, Refereed, Not invited

Functional Mapping of Gustatory Neurons in the Insular Cortex Revealed by pERK-Immunohistochemistry and In Vivo Optical Imaging
Masayuki Kobayashi; Satoshi Fujita; Hiroki Takei; Liqui Song; Shaoyun Chen; Ikuko Suzuki; Atsushi Yoshida; Koichi Iwata; Noriaki Koshikawa
SYNAPSE, Apr. 2010, Refereed, Not invited

PILOCARPINE-INDUCED STATUS EPILEPTICUS CAUSES ACUTE INTERNEURON LOSS AND HYPER-EXCITATORY PROPAGATION IN RAT INSULAR CORTEX
S. Chen; S. Fujita; N. Koshikawa; M. Kobayashi
NEUROSCIENCE, Mar. 2010, Refereed, Not invited

Involvement of NMDA receptors in the ventrolateral striatum of rats in apomorphine-induced jaw movements
Satoshi Fujita; Motori Kiguchi; Masayuki Kobayashi; Noriaki Koshikawa; John L. Waddington
BRAIN RESEARCH, Mar. 2010, Refereed, Not invited

SPATIOTEMPORAL DYNAMICS OF EXCITATION IN RAT INSULAR CORTEX: INTRINSIC CORTICOCORTICAL CIRCUIT REGULATES CAUDAL-ROSTRO EXCITATORY PROPAGATION FROM THE INSULAR TO FRONTAL CORTEX
S. Fujita; K. Adachi; N. Koshikawa; M. Kobayashi
NEUROSCIENCE, Jan. 2010, Refereed, Not invited

Dopamine receptor subtypes and orofacial movement topographies: studies with mutant models
Noriaki Koshikawa; Katsunori Tomiyama; John L. Waddington
Journal of Oral Biosciences, 2010, Refereed, Not invited

Contribution of vesicular and cytosolic dopamine to the increased striatal dopamine efflux elicited by intrastriatal injection of SKF38393
Tadashi Saigusa; Yuri Aono; Reiko Sekino; Takuya Uchida; Koji Takada; Yoshiyuki Oi; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Dec. 2009, Refereed, Not invited

GABA(A) RECEPTORS IN THE MEDIODORSAL THALAMUS PLAY A CRUCIAL ROLE IN RAT SHELL-SPECIFIC ACETYLCHOLINE-MEDIATED, BUT NOT DOPAMINE-MEDIATED, TURNING BEHAVIOUR
H. Ikeda; A. Kotani; J. Lee; N. Koshikawa; A. R. Cools
NEUROSCIENCE, Apr. 2009, Refereed, Not invited

Presynaptic and Postsynaptic Modulation of Glutamatergic Synaptic Transmission by Activation of alpha(1)- and beta-Adrenoceptors in Layer V Pyramidal Neurons of Rat Cerebral Cortex
Masayuki Kobayashi; Masao Kojima; Yuko Koyanagi; Kazunori Adachi; Kazuyuki Imamura; Noriaki Koshikawa
SYNAPSE, Apr. 2009, Refereed, Not invited

Phenotype of spontaneous orofacial dyskinesia in neuregulin-1 'knockout' mice
Katsunori Tomiyama; Colm M. O'Tuathaigh; Gerard J. O'Sullivan; Anthony Kinsella; Donna Lai; Richard P. Harvey; Orna Tighe; David I. Croke; Noriaki Koshikawa; John L. Waddington
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, Mar. 2009, Refereed, Not invited

SOMATOSTATIN RECEPTORS IN THE NUCLEUS ACCUMBENS MODULATE DOPAMINE-DEPENDENT BUT NOT ACETYLCHOLINE-DEPENDENT TURNING BEHAVIOUR OF RATS
H. Ikeda; A. Kotani; N. Koshikawa; A. R. Cools
NEUROSCIENCE, Mar. 2009, Refereed, Not invited

The reboxetine-induced increase of accumbal dopamine efflux is inhibited by l-propranolol: A microdialysis study with freely moving rats
Naoko Mizoguchi; Tadashi Saigusa; Yuri Aono; Reiko Sekino; Koji Takada; Yoshiyuki Oi; Koichiro Ueda; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Dec. 2008, Refereed, Not invited

5-HT_1A and 5-HT_1B receptors in the ventrolateral striatum differentially modulate apomorphine-induced jaw movements in rats
Fujita; S.; Kiguchi; M.; Lee; J.; Terakado; M.; Suga; K.; Hatanaka; H.; Koshikawa; N.
Journal of Oral Science, Dec. 2008, Refereed, Not invited
Corresponding

Behavioural characterisation of rats exposed neonatally to bisphenol-A: responses to a novel environment and to methylphenidate challenge in a putative model of attention-deficit hyperactivity disorder
Motori Kiguchi; Satoshi Fujita; Hidero Oki; Noriyoshi Shimizu; Alexander R. Cools; Noriaki Koshikawa
JOURNAL OF NEURAL TRANSMISSION, Jul. 2008, Refereed, Not invited

Role of GABA(B) receptors in the endomorphin-1-, but not endomorphin-2-, induced dopamine efflux in the nucleus accumbens of freely moving rats
Tadashi Saigusa; Yuri Aono; Naoko Mizoguchi; Tomoyo Iwakami; Koji Takada; Yoshiyuki Oi; Koichiro Ueda; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Mar. 2008, Refereed, Not invited

Role of orexin receptors in the nucleus accumbens in dopamine-dependent turning behaviour of rats
Ayako Kotani; Hiroko Ikeda; Noriaki Koshikawa; Alexander R. Cools
NEUROPHARMACOLOGY, Mar. 2008, Refereed, Not invited

Role of GABA(A) receptors in the endomorphin-1-, but not endomorphin-2-, induced dopamine efflux in the nucleus accumbens of freely moving rats
Yuri Aono; Tadashi Saigusa; Naoko Mizoguchi; Tomoyo Iwakami; Koji Takada; Nobuhito Gionhaku; Yoshiyuki Oi; Koichiro Ueda; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Feb. 2008, Refereed, Not invited

Activation of alpha(1)-adrenoceptors increases firing frequency through protein kinase C in pyramidal neurons of rat visual cortex
Masayuki Kobayashi; Tetsuya Sasabe; Yasuteru Shiohama; Noriaki Koshikawa
NEUROSCIENCE LETTERS, Jan. 2008, Refereed, Not invited

A vehicle injection into the right core of the nucleus accumbens both reverses the region-specificity and alters the type of contralateral turning elicited by unilateral stimulation of dopamine D-2/D-3 and D-1 receptors in the left core of the nucleus accumbens
Hiroko Ikeda; Ayako Kotani; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Dec. 2007, Refereed, Not invited

Behavioral responses to methylphenidate and apomorphine in rats exposed neonatally to bisphenol-A
Kiguchi; M.; Fujita; S.; Lee; J.; Shimizu; N.; Koshikawa; N.
Journal of Oral Science, Dec. 2007, Refereed, Not invited

Role of alpha adrenoceptors in the nucleus accumbens in the control of accumbal noradrenaline efflux: a microdialysis study with freely moving rats
Y. Aono; T. Saigusa; S. Watanabe; T. Iwakami; N. Mizoguchi; H. Ikeda; K. Ishige; K. Tomiyama; Y. Oi; K. Ueda; W.-D. Rausch; J. L. Waddington; Y. Ito; N. Koshikawa; A. R. Cools
JOURNAL OF NEURAL TRANSMISSION, Sep. 2007, Refereed, Not invited

Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods
Kumiko Ishige; Noritaka Takagi; Toru Imai; Wolf Dieter Rausch; Yasuhiro Kosuge; Tetsuroh Kihara; Kuniko Kusama-Eguchi; Hiroko Ikeda; Alexander Rudolf Cools; John Lionel Waddington; Noriaki Koshikawa; Yoshihisa Ito
JOURNAL OF PHARMACOLOGICAL SCIENCES, May 2007, Refereed, Not invited

Differential involvement of cyclase-coupled versus non-cyclase-coupled D-1-like dopamine receptors in orofacial movement topography in mice: Studies with SKF 83822
Yasuyuki Makihara; Yaeko Okuda; Chieko Kawada; Mitsuhiko Matsumoto; John L. Waddington; Noriaki Koshikawa; Katsunori Tomiyama
NEUROSCIENCE LETTERS, Mar. 2007, Refereed, Not invited

Adrenergic receptors in the nucleus accumbens shell differentially modulate dopamine and acetylcholine receptor-mediated turning behaviour
Hiroko Ikeda; Shoko Moribe; Michiko Sato; Ayako Kotani; Noriaki Koshikawa; Alexander R. Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Jan. 2007, Refereed, Not invited

Disruption of orofacial movement topographies in congenic mutants with dopamine D(5) but not D(4) receptor or DARPP-32 transduction 'knockout'
Katsunori Tomiyama; Yasuyuki Makihara; Hiroshi Yamamoto; Gerard O'Sullivan; Rachel E. Nally; Orna Tighe; Anthony Kinsella; Allen A. Fienberg; David K. Grandy; David R. Sibley; David T. Croke; Noriaki Koshikawa; John L. Waddington
EUROPEAN NEUROPSYCHOPHARMACOLOGY, Aug. 2006, Refereed, Not invited

Topographical resolution of jaw movements mediated by cyclase- vs. noncyclase-coupled dopamine D-1-like receptors: Studies with SK&F 83822
S Fujita; J Lee; M Kiguchi; T Uchida; AR Cools; JL Waddinton; N Koshikawa
EUROPEAN JOURNAL OF PHARMACOLOGY, May 2006, Refereed, Not invited

Endomorphin-2 and endomorphin-1 promote the extracellular amount of accumbal dopamine via nonopioid and mu-opioid receptors, respectively
H Okutsu; S Watanabe; Takahashi, I; Y Aono; T Saigusa; N Koshikawa; AR Cools
NEUROPSYCHOPHARMACOLOGY, Feb. 2006, Refereed, Not invited

Effects of alpha-methyl-p-tyrosine on extracellular dopamine levels in the nucleus accumbens and the dorsal striatum of freely moving rats
Watanabe; S.; Fusa; K.; Takada; K.; Aono; Y.; Saigusa; T.; Koshikawa; N.; Cools; A.R.
Journal of Oral Science, Dec. 2005, Refereed, Not invited

Phenotypic studies on dopamine receptor subtype and associated signal transduction mutants: insights and challenges from 10 years at the psychopharmacology-molecular biology interface
JL Waddington; C O'Tuathaigh; G O'Sullivan; K Tomiyama; N Koshikawa; DT Croke
PSYCHOPHARMACOLOGY, Oct. 2005, Refereed, Not invited

Acetylcholine receptor effects on accumbal shell dopamine-mediated turning behaviour in rats
S Moribe; H Ikeda; M Sato; G Akiyama; S Matsuzaki; K Hasegawa; N Koshikawa; AR Cools
NEUROPHARMACOLOGY, Sep. 2005, Refereed, Not invited

Anterior Cingulate cortical neuronal activity during perception of noxious thermal stimuli in monkeys
K Iwata; H Kamo; A Ogawa; Y Tsuboi; N Noma; Y Mitsuhashi; M Taira; N Koshikawa; J Kitagawa
JOURNAL OF NEUROPHYSIOLOGY, Sep. 2005, Refereed, Not invited

Role of GABA(A) receptors in the retrorubral field and ventral pallidum in rat jaw movements elicited by dopaminergic stimulation of the nucleus accumbens shell
T Uchida; K Adachi; S Fujita; J Lee; N Gionhaku; AR Cools; N Koshikawa
EUROPEAN JOURNAL OF PHARMACOLOGY, Mar. 2005, Refereed, Not invited

The non-peptidic delta opioid receptor agonist TAN-67 enhances dopamine efflux in the nucleus accumbens of freely moving rats via a mechanism that involves both glutamate and free radicals
K Fusa; Takahashi, I; S Watanabe; Y Aono; H Ikeda; T Saigusa; H Nagase; T Suzuki; N Koshikawa; AR Cools
NEUROSCIENCE, 2005, Refereed, Not invited

Effects of NMDA and MK-801 injected into the substantia nigra pars reticulata on jaw movements evoked by dopamine D1/D2 receptor stimulation in the ventrolateral striatum: Studies in freely moving rats
T. Uchida; J. Lee; S. Fujita; M. Kiguchi; M. Matsumoto; Y. Oi; N. Gionhaku; Noriaki Koshikawa
Methods and Findings in Experimental and Clinical Pharmacology, Jan. 2005, Refereed, Not invited

Interactions among mu- and delta-opioid receptors, especially putative delta(1)- and delta(2)-opioid receptors, promote dopamine release in the nucleus accumbens
N Hirose; K Murakawa; K Takada; Y Oi; T Suzuki; H Nagase; AR Cools; N Koshikawa
NEUROSCIENCE, 2005, Refereed, Not invited

Contribution of vesicular and cytosolic dopamine to the increased striatal dopamine efflux elicited by intrastriatal injection of dexamphetamine
S Watanabe; Y Aono; K Fusa; K Takada; T Saigusa; N Koshikawa; AR Cools
NEUROSCIENCE, 2005, Refereed, Not invited

Topographical effects of D-1-like dopamine receptor agonists on orofacial movements in mice and their differential regulation via oppositional versus synergistic D1-like : D-2-like interactions: cautionary observations on SK&F 82958 as an anomalous agent
Y Makihara; H Yamamoto; M Inoue; K Tomiyama; N Koshikawa; JL Waddington
JOURNAL OF PSYCHOPHARMACOLOGY, Dec. 2004, Refereed, Not invited

D₁-like dopamine receptor-mediated function in congenic mutants with D₁ vs. D₅ receptor "knockout"
O'Sullivan; G.J.; Clifford; J.J.; Tomiyama; K.; Koshikawa; N.; Drago; J.; Sibley; D.R.; Croke; D.T.; Waddington; J.L.
Journal of Receptors and Signal Transduction Research, Aug. 2004, Refereed, Not invited

Masticatory efficiency before and after surgery in oral cancer patients: comparative study of glossectomy, marginal mandibulectomy and segmental mandibulectomy
Namaki; S.; Matsumoto; M.; Ohba; H.; Tanaka; H.; Koshikawa; N.; Shinohara; M.
Journal of Oral Science, Jun. 2004, Refereed, Not invited

GABA(A) and GABA(B) receptors in the nucleus accumbens shell differentially modulate dopamine and acetylcholine receptor-mediated turning behaviour
G Akiyama; H Ikeda; S Matsuzaki; M Sato; S Moribe; N Koshikawa; AR Cools
NEUROPHARMACOLOGY, Jun. 2004, Refereed, Not invited

Role of mu- and delta-opioid receptors in the nucleus accumbens in turning behaviour of rats
S Matsuzaki; H Ikeda; G Akiyama; M Sato; S Moribe; T Suzuki; H Nagase; AR Cools; N Koshikawa
NEUROPHARMACOLOGY, Jun. 2004, Refereed, Not invited

Deltorphin II enhances extracellular levels of dopamine in the nucleus accumbens via opioid receptor-independent mechanisms
K Murakawa; N Hirose; K Takada; T Suzuki; H Nagase; AR Cools; N Koshikawa
EUROPEAN JOURNAL OF PHARMACOLOGY, Apr. 2004, Refereed, Not invited

Evidence that angiotensin II enhances apomorphine-induced jaw movements via AT₁ receptors in the ventrolateral striatum: studies by magnet-sensing system in freely moving rats
Lee; J.; Adachi; K.; Gionhaku; N.; Fujita; S.; Uchida; T.; Gerstner; G.E.; Koshikawa; N.
Methods and Findings in Experimental and Clinical Pharmacology, Apr. 2004, Refereed, Not invited
Corresponding

Decreased postsynaptic dopaminergic and cholinergic functions in the ventrolateral striatum of spontaneously hypertensive rat
S Fujita; K Adachi; J Lee; T Uchida; N Koshikawa; AR Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Jan. 2004, Refereed, Not invited

Comparative phenotypic resolution of spontaneous D(2)-like and D(1)-like agonist-induced orofacial movement topographies in congenic mutants with dopamine D(2) vs. D(3) receptor "knockout"
K Tomiyama; FN McNamara; JJ Clifford; A Kinsella; J Drago; S Fuchs; DK Grandy; MJ Low; M Rubinstein; O Tighe; DT Croke; N Koshikawa; JL Waddington
SYNAPSE, Jan. 2004, Refereed, Not invited

GABA(A) receptors in the pedunculopontine tegmental nucleus play a crucial role in rat shell-specific dopamine-mediated, but not shell-specific acetylcholine-mediated, turning behaviour
H Ikeda; G Akiyama; S Matsuzaki; M Sato; N Koshikawa; AR Cools
NEUROSCIENCE, 2004, Refereed, Not invited

GABA_A receptors in the nucleus accumbens core modulate turning behavior induced by dopamine receptor stimulation
Akiyama; G.; Ikeda; H.; Matsuzaki; S.; Sato; M.; Moribe; S.; Koshikawa; N.
Journal of Oral Science, Dec. 2003, Refereed, Not invited
Corresponding

Measurement of dopamine receptor-mediated jaw movements by a magnet-sensing system in freely moving rats
Lee; J.; Adachi; K.; Gionhaku; N.; Fujita; S.; Uchida; T.; Koshikawa; N.
Methods and Findings in Experimental and Clinical Pharmacology, Sep. 2003, Refereed, Not invited
Corresponding

Prefrontal, accumbal [shell] and ventral striatal mechanisms in jaw movements and non-cyclase-coupled dopamine D1-like receptors
K Adachi; M Hasegawa; S Fujita; J Lee; AR Cools; JL Waddington; N Koshikawa
EUROPEAN JOURNAL OF PHARMACOLOGY, Jul. 2003, Refereed, Not invited

Altered pre- and postsynaptic dopamine receptor functions in spontaneously hypertensive rat: an animal model of attention-deficit hyperactivity disorder
Fujita; S.; Okutsu; H.; Yamaguchi; H.; Nakamura; S.; Adachi; K.; Saigusa; T.; Koshikawa; N.
Journal of Oral Science, Jun. 2003, Refereed, Not invited
Corresponding

The superior colliculus contains a discrete region involved in the control of jaw movements: role of GABA(A) receptors
K Adachi; M Hasegawa; H Ikeda; M Sato; N Koshikawa; AR Cools
EUROPEAN JOURNAL OF PHARMACOLOGY, Mar. 2003, Refereed, Not invited

Role of AMPA and NMDA receptors in the nucleus accumbens shell in turning behaviour of rats: interaction with dopamine receptors
H Ikeda; G Akiyama; Y Fujii; R Minowa; N Koshikawa; AR Cools
NEUROPHARMACOLOGY, Jan. 2003, Refereed, Not invited

Tyrosine-induced release of dopamine is under inhibitory control of presynaptic dopamine D2 and, probably, D3 receptors in the dorsal striatum, but not in the nucleus accumbens
Fusa; K.; Saigusa; T.; Koshikawa; N.; Cools; A.R.
European Journal of Pharmacology, Jul. 2002, Refereed, Not invited

Dopaminergic and cholinergic stimulation of the ventrolateral striatum elicit rat jaw movements that are funnelled via distinct efferents
Adachi; K.; Hasegawa; M.; Fujita; S.; Sato; M.; Miwa; Y.; Ikeda; H.; Koshikawa. N.; Cools; A.R.
European Journal of Pharmacology, May 2002, Refereed, Not invited
Corresponding

Phenotypic resolution of spontaneous and D(1)-like agonist-induced orofacial movement topographies in congenic dopamine D(1A) receptor 'knockout' mice
K Tomiyama; FN McNamara; JJ Clifford; A Kinsella; J Drago; O Tighe; DT Croke; N Koshikawa; JL Waddington
NEUROPHARMACOLOGY, Apr. 2002, Refereed, Not invited

Ventral striatal vs. accumbal (shell) mechanisms and non-cyclase-coupled dopamine D(1)-like receptors in jaw movements
M Hasegawa; K Adachi; S Nakamura; M Sato; JL Waddington; N Koshikawa
EUROPEAN JOURNAL OF PHARMACOLOGY, Jul. 2001, Refereed, Not invited

Monitoring of extracellular dopamine levels in the dorsal striatum and the nucleus accumbens with 5-minute on-line microdialysis in freely moving rats
Saigusa; T.; Fusa; K.; Okutsu; H.; Koshikawa; N.
Journal of Oral Science, Jun. 2001, Refereed, Not invited

The psychopharmacology-molecular biology interface: exploring the behavioural roles of dopamine receptor subtypes using targeted gene deletion ('knockout')
Waddington; J.L.; Clifford; J.J.; McNamara; F.N.; Tomiyama; K.; Koshikawa; N.; Croke; D.T.
Progress in Neuro-Psychopharmacology and Biological Psychiatory, May 2001, Refereed, Not invited

Site-specific activation of dopamine and serotonin transmission of aniracetam in the mesocorticolimbic pathway of rats
Nakamura; K.; Shirane; M.; Koshikawa; N.
Brain Research, Apr. 2001, Refereed, Not invited

Topographical assessment and pharmacological characterization of orofacial movements in mice: dopamine D(1)-like vs. D(2)-like receptor regulation
K Tomiyama; FN McNamara; JJ Clifford; A Kinsella; N Koshikawa; JL Waddington
EUROPEAN JOURNAL OF PHARMACOLOGY, Apr. 2001, Refereed, Not invited

GABA(A) agents injected into the ventral pallidum differentially affect dopaminergic pivoting and cholinergic circling elicited from the shell of the nucleus accumbens
M Kitamura; H Ikeda; N Koshikawa; AR Cools
NEUROSCIENCE, 2001, Refereed, Not invited

Effects of Saiko-ka-ryukotsu-borei-to on spontaneous locomotor activity in mice
Imai; T.; Takahashi; I.; Yamauchi; M.; Sawada; S.; Sato; M.; Koshikawa; N.
Journal of Oral Science, Sep. 2000, Refereed, Not invited
Corresponding

In vivo microdialysis evidence that midazolam facilitates propofol-induced reduction in rat accumbal dopamine release
Yoshida; Y.; Koide; S.; Hirose; N.; Takada; K.; Saigusa; T.; Koshikawa; N.
Neuroscience Research Communications, Dec. 1999, Refereed, Not invited
Corresponding

Effects of chronic haloperidol and clozapine on vacuous chewing and dopamine-mediated jaw movements in rats: evaluation of a revised animal model of tardive dyskinesia
Ikeda; H.; Adachi; K.; Hasegawa; M.; Sato; M.; Hirose; N.; Koshikawa; N.; Cools; A.R.
Journal of Neural Transmission, Dec. 1999, Refereed, Not invited
Corresponding

Behavioural and neurochemical effects of cholinergic and dopaminergic agonists administered into the accumbal core and shell in rats
Kitamura; M.; Koshikawa; N.; Yoneshige; N.; Cools; A.R.
Neuropharmacology, Sep. 1999, Refereed, Not invited
Corresponding

Fentanyl increases dopamine release in rat nucleus accumbens: involvement of mesolimbic mu- and delta-2-opioid receptors
Yoshida; Y.; Koide; S.; Hirose; N.; Takada; K.; Tomiyama; K.; Koshikawa; N.; Cools; A.R.
Neuroscience, Jun. 1999, Refereed, Not invited
Corresponding

SK & F 83959 and non-cyclase-coupled dopamine D(1)-like receptors in jaw movements via dopamine D(1)-like/D(2)-like receptor synergism
K Adachi; H Ikeda; M Hasegawa; S Nakamura; JL Waddington; N Koshikawa
EUROPEAN JOURNAL OF PHARMACOLOGY, Feb. 1999, Refereed, Not invited

High and low responders to novelty: effects of a catecholamine synthesis inhibitor on novelty-induced changes in behaviour and release of accumbal dopamine
Saigusa; T.; Tuinstra; T.; Koshikawa; N.; Cools; A.R.
Neuroscience, Feb. 1999, Refereed, Not invited

Effects of propofol and fentanyl on extracellular levels of gamma-aminobutyric acid in the rat nucleus accumbens: An in vivo microdialysis study
Hirose; N.; Yoshida; Y.; Koide; S.; Takada; K.; Saigusa; T.; Koshikawa; N.
Journal of Oral Science, Dec. 1998, Refereed, Not invited
Corresponding

Clonidine reduces dopamine and increases GABA in the nucleus accumbens: an in vivo microdialysis study
Murai; T.; Yoshida; Y.; Koide; S.; Takada; K.; Misaki; T.; Koshikawa; N.; Cools; A.R.
Pharmacology Biochemistry and Behavior, Jul. 1998, Refereed, Not invited
Corresponding

Effects of Hochu-ekki-to on spontaneous locomotor activity in mice
Imai; T.; Takahashi; I.; Yamauchi; M.; Sawada; S.; Sato; M.; Yoneshige; N.; Koshikawa; N.
Japanese Journal of Psychosomatic Dentistry, Jun. 1998, Refereed, Not invited
Corresponding

Chronic treatment with tianeptine attenuates the behavioural effects induced by 5-HTP, but not the effects on hippocampal 5-HT concetrations
Koshikawa; N.; Kitamura; M.; Tomiyama; K.; Stephenson; J.D.
Neuroscience Research communications, Apr. 1998, Refereed, Not invited
Lead

Differential effects of YM-14673, a thyrotropin-releasing hormone analogue, on dopamine release in the dorsal and ventrolateral division of the striatum of rats
Tomiyama; K.; Koide; S.; Adachi; K.; Koshikawa; N.; Kobayashi; M.
Neuroscience Research Communications, Feb. 1998, Refereed, Not invited
Corresponding

Effects of Hochu-ekki-to, Yoku-kan-san and Saiko-ka-ryukotsu-borei-to on behavioral despair and acetic acid-induced writhing in mice
Noriaki Koshikawa; Takao Imai; Ichiro Takahashi; Michiko Yamauchi; Shigeki Sawada; Ai Kansaku
Methods and Findings in Experimental and Clinical Pharmacology, Jan. 1998, Refereed, Not invited

Effects of YM-14673, a thyrotropin-releasing hormone analogue, injected into the shell and the core of the nucleus accumbens on production of repetitive jaw movements in rats: Comparison with the effects of dopamine D₁ and D₂ receptor agonists combination
Adachi; K.; Hirose; N.; Fujioka; H.; Yoneshige; N.; Koshikawa; N.
The Journal of Nihon University School of Dentistry, Sep. 1997, Refereed, Not invited
Corresponding

Contralateral turning elicited by unilateral stimulation of dopamine D₂ and D₁ receptors in the nucleus accumbens of rats is due to stimulation of these receptors in the shell, but not the core, of this nucleus
Koshikawa; N.; Kitamura; M.; Kobayashi; M.; Cools; A.R.
Psychopharmacology, Aug. 1996, Refereed, Not invited
Lead

Behavioural effects of 7-OH-DPAT are solely due to stimulation of dopamine D₂ receptors in the shell of the nucleus accumbens; jaw movements
Koshikawa; N.; Miwa; Y.; Adachi; K.; Kobayashi; M.; Cools; A.R.
European Journal of Pharmacology, Jul. 1996, Refereed, Not invited
Lead

Behavioural effects of 7-OH-DPAT are solely due to stimulation of dopamine D₂ receptors in the shell of the nucleus accumbens; turning behaviour
Koshikawa; N.; Kitamura; M.; Kobayashi; M.; Cools; A.R.
European Journal of Pharmacology, Jul. 1996, Refereed, Not invited
Lead

Stimulation of acetylcholine or dopamine receptors in the nucleus accumbens differentially alters dopamine release in the striatum of freely moving rats
Koshikawa; N.; Yoshida; Y.; Kitamura; M.; Saigusa; T.; Kobayashi; M.; Cools; A.R.
European Journal of Pharmacology, May 1996, Refereed, Not invited
Lead

Anatomical connections of the ventral, but not the dorsal part of the striatum with the parvicellular reticular formation: implications for the anatomical substrate of oral movements
Iwata; K.; Yagi; J.; Tsuboi; Y.; Koshikawa; N.; Sumino; R.; Cools; A.R.
Neuroscience Research Communications, Apr. 1996, Refereed, Not invited
Corresponding

In vivo microdialysis evidence for transient dopamine release by local injecton of clozapine into rat dorsal striatum
Tomiyama; K.; Funada; K.; Isogawa; M.; Fujioka; H.; Koshikawa; N.; Kobayashi; M.
Methods and Findings in Experimental and Clinical Pharmacology, Mar. 1996, Refereed, Not invited
Corresponding

Effects of clozapine injected into the dorsal region of the striatum on apomorphine-induced jaw movements in rats
Miwa; Y.; Kikuchi de Beltran; K.; Takakusaki; K.; Hayakawa; H.; Ishii; K.; Koshikawa; N.; Kobayashi; M.
Methods and Findings in Experimental and Clinical Pharmacology, Mar. 1996, Refereed, Not invited
Corresponding

In vivo microdialysis evidence for transient dopamine release by benzazepines in rat striatum
Tomiyama; K.; Koshikawa; N.; Funada; K.; Oka; K.; Kobayashi; M.
Journal of Neurochemistry, Dec. 1995, Refereed, Not invited
Corresponding

ROLE OF DOPAMINE D-1 AND D-2 RECEPTOR IN THE NUCLEUS-ACCUMBENS IN JAW MOVEMENTS OF RATS - A CRITICAL ROLE OF THE SHELL
AR COOLS; Y MIWA; N KOSHIKAWA
EUROPEAN JOURNAL OF PHARMACOLOGY, Nov. 1995, Refereed, Not invited

YM-14673, a thyrotropin-releasing hormone analogue, injected into the nucleus accumbens and the striatum produces repetitive jaw movements in rats
Miwa; Y.; Koshikawa; N.; Miyata; N.; Koshida; Y.; Kobayashi; M.; Cools; A.R.
European Journal of Pharmacology, Apr. 1995, Refereed, Not invited
Corresponding

Dissimilarities between cholinergic and dopaminergic turning elicited by nucleus accumbens stimulation in freely moving rats
Saigusa; T.; Koshikawa; N.; Kitamura; M.; Mizutani; K.; Kobayashi; M.; Cools; A.R.
European Journal of Pharmacology, Feb. 1995, Refereed, Not invited
Corresponding

Clozapine injected into the nucleus accumbens potentiates apomorphine-induced jaw movements
Kikuchide Beltrán; K.; Koshikawa; N.; Miwa; Y.; Kobayashi; M.; Cools; A.R.
European Journal of Pharmacology, Sep. 1994, Refereed, Not invited
Corresponding

Opposite effects of midazolam and β-carboline-3-carboxylate ethyl ester on the release of dopamine from rat nucleus accumbens measured by in vivo microdialysis
Murai; T.; Koshikawa; N.; Kanayama; T.; Takada; K.; Tomiyama; K.; Kobayashi; M.
European Journal of Pharmacology, Aug. 1994, Refereed, Not invited
Corresponding

Dorsal striatal dopamine D₁ and D₂ receptors are involved in the carbachol-mediated potentiation of apomorphine-induced jaw movements
Kikuchi de Beltrán; K.; Koshikawa; N.; Miwa; Y.; Kobayashi; M.; Cools; A.R.
Neuroscience Research Communications, Feb. 1994, Refereed, Not invited
Corresponding

Dorsal striatal mechanisms involved in the dopamine D₂ receptor-mediated potentiation of apomorphine-induced jaw movements
Kikuchi de Beltrán; K.; Koshikawa; N.; Miwa; Y.; Kobayashi; M.
European Journal of Pharmacology, Jan. 1994, Refereed, Not invited
Corresponding

Role of the Nucleus Accumbens and the Striatum in the Production of Turning Behaviour in Intact Rats
Noriaki Koshikawa
Reviews in the Neurosciences, 1994, Refereed, Not invited

Further evidence for a functional dorsal-ventral division of the rat striatum: GABAergic involvement in oral movements
Kikuchi de Beltrán; K.; Koshikawa; N.; Miwa; Y.; Kobayashi; M.; Stephenson; J.D.
European Journal of Pharmacology, Aug. 1993, Refereed, Not invited
Corresponding

Differential role of core and shell of the nucleus accumbens in jaw movements of rats
Cools; A.R.; Kikuchi de Beltrán; K.; Prinssen; E.P.M.; Koshikawa; N.
Neuroscience Research Communications, Aug. 1993, Refereed, Not invited
Corresponding

Reevaluation of the two-component hypothesis for turning behaviour by manipulating activities in the striatum and the nucleus accumbens of intact rats
Saigusa; T.; Koshikawa; N.; Kitamura; M.; Kobayashi; M.
European Journal of Pharmacology, Jun. 1993, Refereed, Not invited
Corresponding

YM-09151-2 but not l-sulpiride induces transient dopamine release in rat striatum via a tetrodotoxin-insensitive mechanism
Tomiyama; K.; Noguchi; M.; Koshikawa; N.; Kobayashi; M.
Journal of Neurochemistry, May 1993, Refereed, Not invited
Corresponding

Effects of midazolam and flunitrazepam on the release of dopamine from rat striatum measured by in vivo microdialysis
Takada; K.; Murai; T.; Kanayama; T.; Koshikawa; N.
British Journal of Anaesthesia, Feb. 1993, Refereed, Not invited
Corresponding

Cholinergic/dopaminergic interaction in the rat striatum assessed from drug-induced repetitive oral movements
Kikuchi de Beltrán; K.; Koshikawa; N.; Saigusa; T.; Watanabe; K.; Koshida; Y.; Kobayashi; M.
European Journal of Pharmacology, Apr. 1992, Refereed, Not invited
Corresponding

Cholecystokinin octapeptide and caerulein injection into the dorsomedial nucleus accumbens potentiate apomorphine-induced jaw movements in rats
Koshikawa; N.; Kikuchi de Beltrán; K.; Saigusa; T.; Kobayashi; M.; Stephenson; J.D.
European Journal of Pharmacology, Dec. 1991, Refereed, Not invited
Lead

Functional interaction between dopamine D₁ and D₂ receptors in rat jaw movements
Koshikawa; N.; Kikuchi de Beltrán; K.; Tomiyama; K.; Kobayashi; M.; Cools; A.R.
European Journal of Pharmacology, Aug. 1991, Refereed, Not invited
Lead

THE EFFECTS OF TIANEPTINE ON WET-DOG SHAKES, FORE-PAW TREADING AND A FLEXOR REFLEX IN RATS ARE CONSISTENT WITH ENHANCEMENT OF 5-HYDROXYTRYPTAMINE UPTAKE
N KOSHIKAWA; E MOCAER; JD STEPHENSON
EUROPEAN JOURNAL OF PHARMACOLOGY, May 1991, Refereed, Not invited

Effects of dopamine D₁ and D₂ agonists and antagonists injected into the nucleus accumbens and globus pallidus on jaw movements of rats
Koshikawa; N.; Koshikawa; F.; Tomiyama; K.; Kikuchi de Beltrán; K.; Kamimura; F.; Kobayashi; M.
European Journal of Pharmacology, Jul. 1990, Refereed, Not invited
Lead

Central dopaminergic actions of YM-14673, a new TRH analogue, in rodents
Yamamoto; M.; Ozawa; Y.; Sasamata; M.; Koshikawa; N.; Kobayashi; M.
European Journal of Pharmacology, May 1990, Refereed, Not invited

Further evidence for an anomalous regulation of cortical 5-HT₂ receptors: studies with 5-HT precursors
Koshikawa; N.; Koshikawa; F.; Stephenson; J.D.
European Journal of Pharmacology, Mar. 1990, Refereed, Not invited
Lead

Dopamine D-1 but not D-2 receptor stimulation of the dorsal striatum potentiates apomorphine-induced jaw movements in rats
Koshikawa; N.; Tomiyama; K.; Omiya; K.; Kikuchi de Beltrán; K.; Kobayashi; M.
European Journal of Pharmacology, Mar. 1990, Refereed, Not invited
Lead

Role of dopamine D-1 and D-2 receptors in the ventral striatum in the turning behaviour of rats
Koshikawa; N.; Mori; E.; Maruyama; Y.; Yatsushige; N.; Kobayashi; M.
European Journal of Pharmacology, Mar. 1990, Refereed, Not invited
Lead

Rapid development of brain β-adrenoceptor down-regulation induced by phenelzin: subcellular studies
Koshikawa; N.; Maruyama; Y.; Kobayashi; M.; Campbell; I.C.
European Journal of Pharmacology, Oct. 1989, Refereed, Not invited
Lead

Effects of SCH 23390 injection into the dorsal striatum and nucleus accumbens on methamphetamine-induced gnawing and hyperlocomotion in rats
Koshikawa; N.; Mori; E.; Oka; K.; Nomura; H.; Yatsushige; N.; Maruyama; Y.
The Journal of Nihon University School of Dentistry, Jun. 1989, Refereed, Not invited
Lead

Production of wet-dog shakes in rats and down-regulation of spinal 5-HT₂ receptors
Koshikawa; N.; Maruyama; Y.; Stephenson; J.D.
European Journal of Pharmacology, May 1989, Refereed, Not invited
Lead

Effects of intrastriatal injections of selective dopamine D-1 and D-2 agonists and antagonists on jaw movements of rats
Noriaki Koshikawa; Shigeo Aoki; Masako Hiruta; Katsunori Tomiyama; Masafumi Kobayashi; Yoshiyuki Tsuboi; Koichi Iwata; Ryuji Sumino; John D. Stephenson
European Journal of Pharmacology, Apr. 1989, Refereed, Not invited

Changes in cortical 5-HT₂ receptors following 5-HTP and paroxetine administration in rats
Koshikawa; N.; Maruyama; Y.; Oka; K.; Nomura; H.; Mori; E.; Kobayashi; M.; Stephenson; J.D.
The Journal of Nihon University School of Dentistry, Sep. 1988, Refereed, Not invited
Lead

An examination of experimental design in relation to receptor binding assays
Dunn; G.; Koshikawa; N.; Durcan; M.J.; Campbell; I.C.
British Journal of Pharmacology, Jul. 1988, Refereed, Not invited

Circadian studies of 5HT₂ receptors: effects of clorgyline administration
Koshikawa; N.; Durcan; M.J.; Dunn; G.; Campbell; I.C.
Pharmacology Biochemistry and Behaviour, Jun. 1988, Refereed, Not invited
Lead

Ketamine anaesthesia has no effect on striatal dopamine metabolism in rats
Koshikawa; N.; Tomiyama; K.; Omiya; K.; Kobayashi; M.
Brain Research, Mar. 1988, Refereed, Not invited
Lead

Subcellular distribution of β-adrenoceptors in brain following administration of antidepressant drugs
Koshikawa; N.; Durcan; M.J.; Weaver; K.; Lawrence; K.; Campbell; I.C.
Neuropharmacology, Sep. 1987, Refereed, Not invited
Lead

In vivo voltammetric study of cortical 5-HT after administration of 5-HTP or paroxetine to phenelzine treated rats
Aoki; S.; Koshikawa; N.; Kobayashi; M.; Stephenson J.D.
The Journal of Nihon University School of Dentistry, Sep. 1987, Refereed, Not invited
Corresponding

Sulpiride injection into the dorsal striatum increases methamphetamine-induced gnawing in rats
Koshikawa; N.; Aoki; S.; Tomiyama; K.; Maruyama; Y.; Kobayashi; M.
European Journal of Pharmacology, Jan. 1987, Refereed, Not invited
Lead

Monitoring of dopamine metabolism by in vivo voltammetry and high performance liquid chromatography in L-DOPA-treated rats
Aoki; S.; Inukai; K.; Sakurai; M.; Koshikawa; N.; Kobayashi; M.
Japanese Journal of Pharmacology, Jan. 1987, Refereed, Not invited
Corresponding

Effects of sulpiride injection into the dorsal striatum and the nucleus accumbens on dopamine-mediated oral stereotypy and hyperlocomotion in rats
Koshikawa; N.; Aoki; S.; Imai; E.; Kobayashi; M.
The Journal of Nihon University School of Dentistry, Jun. 1986, Refereed, Not invited
Lead

Effects of antidepressant drug combinations on cortical 5-HT₂ receptors and wet-dog shakes in rats
Koshikawa; F.; Koshikawa; N.; Stephenson; J.D.
European Journal of Pharmacology, Dec. 1985, Refereed, Not invited

Is waning of a 5-hydroxytryptamine(5-HT)-mediated syndrome due to 5-HT₂ receptor down-regulation?
Koshikawa; N.; Smokcum; R.W.J.; Stephenson; J.D.
Neuroscience Letters, May 1985, Refereed, Not invited
Lead

Behavioral pharmacology of orofacial movement disorders. In: Translating Mechanisms of Orofacial Neurological Disorder; International Review of Neurobiology Vol. 97
Koshikawa, N; Fujita, S; Adachi, K, Joint work, 1-38, Koshikawa; N.; Fujita; S.; Adachi; K.
Academic Press, Jun. 2011, Not refereed
9780123851987

Chapter 12: Mutant and Transgenic Tools in Modeling Schizophrenia. In: Transgenic and Mutant Tools to Model Brain Disorders; Springer Protocols, Neuromethods, Vol. 44
Desbonnet, L; Tomiyama, K; Koshikawa, N; O’Tuathaigh; C.M.P; Waddington, J.L; Eds. Kalueff; A.V; Bergner, Joint work, 217-239, Desbonnet; L.; Tomiyama; K.; Koshikawa; N.; O’Tuathaigh; C.M.P.; Waddington; J.L. (Eds. Kalueff; A.V.; Bergner; C.L.)
Humana Press, Apr. 2010, Not refereed
9781607614746

Chapter 13: Dopamine receptors and behavior: from psychopharmacology to mutant models. In: The Dopamine Receptors 2nd Ed
O’Sullivan, G.J; O’Tuathaigh, C; Tomiyama, K; Koshikawa, N; Waddington; J.L. (Ed; Neve, K, Joint work, 323-371, O’Sullivan; G.J.; O’Tuathaigh; C.; Tomiyama; K.; Koshikawa; N.; Waddington; J.L. (Ed; Neve; K.A.)
Humana Press, Jan. 2010, Not refereed
9781603273329

Dental pharmacology 5th ed
石田甫; 大浦清; 上﨑善規; 土肥敏博; 編; 五十嵐治義; 川口充; 北村憲司; 越川憲明; 村上伸也; 石川康子; 柏俣正典; 川島博行; 北山滋雄; 雫石聰; 西川殷維; 山本隆; 加藤幸夫; 河原道夫; 木村智彦; 千葉有; 丹羽均; 吉山昌宏; 梅本俊夫; 菊谷仁; 古郷幹彦; 筒井健機; 増田裕次; 和田孝一郎; 井上紀子; 入舩正浩; 北村正博; 佐伯万騎男; 佐藤友昭; 篠原光子; 永田英樹; 野﨑中成, Joint work, 169-172, 362-371, 378-379, 380-383, 石田甫・大浦清・上﨑善規・土肥敏博 編/五十嵐治義・川口充・北村憲司・越川憲明・村上伸也・石川康子・柏俣正典・川島博行・北山滋雄・雫石聰・西川殷維・山本隆・加藤幸夫・河原道夫・木村智彦・千葉有・丹羽均・吉山昌宏・梅本俊夫・菊谷仁・古郷幹彦・筒井健機・増田裕次・和田孝一郎・井上紀子・入舩正浩・北村正博・佐伯万騎男・佐藤友昭・篠原光子・永田英樹・野﨑中成 執筆
Ishiyaku Publishers Inc., Mar. 2005, Not refereed
4263455827

スタンダード歯学薬理学 第２版
編著 川口; 充; 五十嵐治義; 大浦 清; 北村憲司; 越川憲明; 千葉元つぐ; 東城庸介; 戸苅彰史; 藤井 彰; 前橋; 浩 著; 新井通次; 大久保つや子; 岡部栄逸朗; 澤木康平; 篠原光子; 塗々木和夫茂木眞希雄; 矢崎欽也; 山崎 純; 山根潤一; 松本仁人; 王 久子, Joint work, 3-11, 253-261, 309-313, 412-419, 420-424, 編著 川口 充 五十嵐治義 大浦 清 北村憲司 越川憲明 千葉元つぐ 東城庸介 戸苅彰史 藤井 彰 前橋 浩 著 新井通次 大久保つや子 岡部栄逸朗 澤木康平 篠原光子 塗々木和夫茂木眞希雄 矢崎欽也 山崎 純 山根潤一 松本仁人 王 久子
学建書院, Mar. 2001, Not refereed
9784762406249

Dental Pharmacology 4th ed
石田 甫; 大浦 清; 齋藤喜八; 土肥敏博, Joint work, 137-151, 石田 甫; 大浦 清; 齋藤喜八; 土肥敏博 編
Ishiyaku Publishers Inc., Jun. 1997, Not refereed
4263453700

Behavioural and biochemical evidence that cholinergic or dopaminergic stimulation in the nucleus accumbens differentially alters dopaminergic activities in rat ventrolateral striatum. Advances in Behavioral Biology･Volume 47: The basal ganglia V
Koshikawa, N; Yoshida, Y; Kitamura, M; Saigusa, T; Cools, A.R; Eds. Ohye, C; Kimura, M; McKenzie, J, Joint work, 105-111, Koshikawa; N.; Yoshida; Y.; Kitamura; M.; Saigusa; T.; Cools; A.R. (Eds. Ohye; C.; Kimura; M. and McKenzie; J.S.)
Plenum Press, Jan. 1997, Not refereed
030645386X

うつ病: 神経伝達物質－薬物作用と疾患－
小林雅文; 越川憲明; 福田英臣; 栗山欣彌編, Joint work, 361-397, 小林雅文; 越川憲明 (瀬川富朗; 福田英臣; 栗山欣彌編)
広川書店, Nov. 1991, Not refereed
9784567496605

アドレナリン神経系, 抗うつ薬およびうつ病: 精神疾患の生物学的研究
Campbell, I.C; 越川憲明, Joint work, 83-115, Campbell; I.C.; 越川憲明 (稲永和豊編)
医学書院, Jun. 1988, Not refereed
4260117327

こころと物質との接点：Monado Books 24
小林雅文; 越川憲明, Joint work, 1-92, 小林雅文; 越川憲明
海鳴社, Dec. 1983, Not refereed
9784875250234

Activation of fast-spiking GABAergic neurons in the agranular insular cortex from the piriform cortex
Yamamoto; K.; Koshikawa; N.; Kobayashi; M.
The 13th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception, Nov. 2015, Not invited

Propofol facilitates pyramidal cells firing synchrony in rat cerebral cortex
Koyanagi; Y.; Oi; Y.; Koshikawa; N.; Kobayashi; M.
Neuroscience 2015, Oct. 2015, Not invited

Spatial profile of neural excitation in rat insular cortex evoked by electrical stimulation of tooth pulp: an optical imaging study
Nakamura; H.; Shirakawa; T.; Koshikawa; N.; Kobayashi; M.
5th International congress on Neuropathic Pain, May 2015, Not invited

Propofol preferentially enhances fast-spiking interneuron connections to pyramidal neurons in rat insular cortex
Koyanagi; Y.; Oi; Y.; Koshikawa; N.; Kobayashi; M.
Anesthesiology2014, Oct. 2014, Not invited

Propofol induced spike synchrony of pyramidal cells in rat derebral cortex
Koyanagi; Y.; Oi; Y.; Koshikawa; N.; Kobayashi; M.
The 9th International Symposium on Memory and Awareness in Anesthesia, Jul. 2014, Not invited

Intra-accumbal administration of endomorphin-2 decreases acetylcholine efflux via mu receptors and increases dopamine efflux independent of mu receptors in the nucleus accumbens of freely moving rats
Aono; Y.; Taguchi; H.; Kiguchi; Y.; Uchida; T.; Takada; K.; Koshikawa; N.; Saigusa; T.
29th The International College of Neuropsychopharmacology (CINP), Jun. 2014, Not invited

Functional mapping of excitatory synaptic inputs in the agranular insular cortex
Yamamoto; K.; Koshikawa; N.; Kobayashi; M.
Society for Neuroscience 2013, Nov. 2013, Society for Neuroscience, Not invited

Reciprocal regulation of inhibitory synaptic transmission by nicotinic and muscarinic receptors in rat nucleus accumbens shell
Ebihara; K.; Yamamoto; K.; Ueda; K.; Koshikawa; N.; Kobayashi; M.
Society for Neuroscience 2013, Nov. 2013, Society for Neuroscience, Not invited

Leptin-induced suppression of excitatory propagation in the insular cortex
Kobayashi; M.; Takei; H.; Koshikawa; N.:
The 10th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception (YR Umami Forum 2012), Nov. 2012, Not invited

P/Q-type voltage-dependent calcium channels determine release probability of GABAergic synapses in rat gustatory cortex
Yamamoto; K.; Koshikawa; N.; Kobayashi; M.
The 10th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception (YR Umami Forum 2012), Nov. 2012, Not invited

Characteristic features of layer II/III neurons in rat insular cortex
Adachi; K.; Koshikawa; N.; Kobayashi; M.
Neuroscience 2012, Oct. 2012, Not invited

In vivo voltage-sensitive dye imaging of insular cortex in a rat model of temporal lobe epilepsy
Fujita; S.; Chen; S.; Mizoguchi; N.; Koshikawa; N.; Kobayashi; M.
Gordon Research Conferences, Mechanisms of Epilepsy & Neuronal Synchronization, Aug. 2012, Not invited

Cholinergic modulation of inhibitory synaptic transmission among medium spiny neurons in rat nucleus accumbens
Ebihara; K.; Ueda; K.; Yamamoto; K.; Koshikawa; N.; Kobayashi; M.
8th Forum of European Neuroscience, Jul. 2012, Not invited

Alpha-1-, but not alpha-2-adrenoceptor in the nucleus accumbens exerts an inhibitory control upon the accumbal noradrenaline and dopamine efflux in freely moving rats
Saigusa; T.; Aono; Y.; Koshikawa; N.; Cools; A.R.
28th CINP Congress, Jun. 2012, Not invited

Simultaneous, but not separate activation of beta-1- and beta-2-adrenoceptors in the nucleus accumbens increases accumbal dopamine efflux in freely moving rats
Aono; Y.; Saigusa; T.; Uchida; T.; Koshikawa; N.; Cools; A.R.
28th CINP Congress, Jun. 2012, Not invited

Spontaneous involuntary movements are an integral component of network dysfunction in schizophrenia
Waddington J; Tomiyama K; Koshikawa N.
3rd European Conference on Schizophrenia Research [ECSR], Sep. 2011, Not invited

The alpha-1 adrenoceptor in the nucleus accumbens exerts an inhibitory control upon the accumbal noradrenaline and dopamine efflux in freely moving rats
Saigusa; T.; Aono; Y.; Uchida; T.; Cools; A.R.; Koshikawa; N.
2nd Congress of Asian College of Neuropsychopharmacology, Sep. 2011, Not invited

Postsynaptic cell type-dependent cholinergic regulation of GABAergic synaptic transmission in rat insular cortex
Yamamoto; K.; Koshikawa; N.; Kobayashi; M.
40th Annual Meeting, Neuroscience 2010, Nov. 2010, Not invited

Pilocarpine-induced status epilepticus causes hyper-excitatory propagation and interneuron loss in rat agranular insular cortex
Fujita; S.N.; Chen; S.; Mizoguchi; N.; Koshikawa; N.; Kobayashi; M.
40th Annual Meeting, Neuroscience 2010, Nov. 2010, Not invited

β-Adrenoceptors differentially regulate inhibitory synaptic transmission depending on presynaptic interneuron subtype in rat cerebral cortex
Koyanagi1; Y.; Oi; Y.; Koshikawa; N.; Kobayashi M.
40th Annual Meeting, Neuroscience 2010, Nov. 2010, Not invited

Functional connectivity of rat insular cortex revealed by optical imaging technique
Fujita; S.; Kobayashi; M.; Koshikawa; N.
39th Annual Meeting, Neuroscience 2009, Oct. 2009, Not invited

Functional mapping of gastatory neurons in the insular cortex revealed by pERK-immunohistochemistry and in vivo optical imaging
Kobayashi; M.; Fujita; S.; Koshikawa; N.
39th Annual Meeting, Neuroscience 2009, Oct. 2009, Not invited

Cholinergic or dopaminergic stimulation in the nucleus accumbens produces turning behaviour via different pathways
Ikeda; H.; Koshikawa; N. Cools; AR.
39th Annual Meeting, Neuroscience 2009, Oct. 2009, Not invited

Functional connectivity in rat insular cortex revealed by in vivo optical imaging
Fujita; S.; Adachi; K.; Koshikawa; N.; Kobayashi; M.
XXXVI International Congress of Physiological Sciences, Jul. 2009, Not invited

Physiological features of pyramidal cells in rat insular cortex revealed by in vivo whole-cell patch clamp recording
Adachi; K.; Fujita; S.; Sakagami; H.; Koshikawa; N.; Kobayashi; M.
XXXVI International Congress of Physiological Sciences, Jul. 2009, Not invited

Differential modulation of glutamatergic and GABAergic synaptic transmission by activating alpha1- and beta-adrenoceptors in rat cerebral cortex
Koyanagi; Y.; Kobayashi; M.; Koshikawa; N.
Federation of European Neuroscience Societies (FENS) Forum 2008, Jul. 2008, Not invited

ATP tooth pulp stimulation evokes brainstem reflexes and ERK phosphorylation
Adachi; K.; Shimizu; K.; Hu; J.W.; Iwata; K.; Koshikawa; N.; Sessle; B.
86th International Association for Dental Research (IADR) General Session, Jul. 2008, Not invited

Regulation of topographies of orofacial movement using mutant models. Simposiun: New applications of mutant models for neuropsychiatric disorders
Tomiyama; K; O’Tuathaigh; C . M.; O’Sullivan; G.; Clifford; J. J.; Harvey; R.; Croke; D.; Koshikawa; N.; Waddington; J.
CINP Pacific-Asia Regional Meeting, Mar. 2008, Invited

Effects of a GABA_B receptor antagonist and agonist on the endomorphin-1- and endomorphin-2-induced dopamine efflux in the nucleus accumbens of freely moving rats
Iwakami; T.; Saigusa; T.; Aono; Y.; Miziguchi; N.; Ueda; K.; Koshikawa; N.; Cools; A. R.
7th International Brain Research Organization (IBRO) World Congress of Neuroscience, Jul. 2007, Not invited

Effects of a GABA_A receptor agonist and antagonist on the endomorphin-1- and endomorphin-2-induced dopamine efflux in the nucleus accumbens of freely moving rats
Miziguchi; N.; Saigusa; T.; Aono; Y.; Iwakami; T.; Ueda; K.; Koshikawa; N.; Cools; A. R.
7th International Brain Research Organization (IBRO) World Congress of Neuroscience, Jul. 2007, Not invited

Behavioural characterization of different dopamine D1-like receptors against the D2-like antagonist
富山勝則; 川田智恵子; 奥田八重子; 松本光彦; 越川憲明; ワディントン ジョン: Tomiyama; K.; Kawada; C.; Okuda; Y.; Matsumoto; M.; Koshikawa; N.; Waddington; J.
36th Annual Meeting of the Japanese Society of Neuropsychopharmacology, Sep. 2006, Not invited

Role of GABA_A receptors in the mediodorsal thalamus in rat turning behaviour
池田弘子; 小谷彩子; 佐藤充子; 越川憲明: Ikeda; H.; Kotani; A.; Sato; M.; Koshikawa; N.
36th Annual Meeting of the Japanese Society of Neuropsychopharmacology, Sep. 2006, Not invited

Inhibitory neuron loss in the piriform cortex in a model of temporal lobe epilepsy
Kobayashi; M.; Chen; S.; Koshikawa N.
28th Annual Meeting of the Japanese Society of Biological Psychiatry, Sep. 2006, Not invited

The psychoneuropharmacology of orofacial dyskinesias
Koshikawa N.
Symposium on the Retirement of Prof Alexander Cools (Nijmegen University), Sep. 2006, Not invited

Inhibition of GABA_B receptors, but not GABA_A receptors, enhances the endomorphin-1-, but not endomorphin-2-, induced increase of the accumbal dopamine efflux in rats
Aono Y.; Saigusa T.; Mizoguchi N.; Iwakami T.; Ueda K.; Koshikawa N.; Cools A. R.
5th Forrum of European Neuroscinece, Jul. 2006, Not invited

Presynaptic alpha-adrenoceptors in the nucleus accumbens exert an inhibitory control upon the release of accumbal noradrenaline in rats
Saigusa T.; Aono Y.; Iwakami T.; Mizoguchi N.; Watanabe S.; Ueda K.; Koshikawa N.; Cools A. R.
5th Forrum of European Neuroscinece, Jul. 2006, Not invited

Interactions among mu- delta₁- and delta₂-opioid receptors promote dopamine release in the nucleus accumbens
Koshikawa; N.; Hirose; N.; Lee; J.; Cools; A.R.
18th European College of Neuropsychopharmacology (ECNP) Congress, Oct. 2005, Not invited

Role of GABA_A receptors in the substantia nigra pars reticulata in rat turning behaviour
Ikeda; H.; Moribe; S.; Sato; M.; Koshikawa; N.; Cools; A.R.
18th European College of Neuropsychopharmacology (ECNP) Congress, Oct. 2005, Not invited

Role of striatal dopamine-angiotensin mechanisms in the production of rat jaw movements
Koshikawa N; Lee J; Adachi K; Gionhaku N; Fujita S; Uchida T.
XXIVth Collegium Internationale Neuro-Psychopharmacologicum (CINP) congress in Paris, Jun. 2004, Not invited

Role of GABA_A receptors in the pedunculopontine tegmental nucleus in rat turning behaviour
Ikeda H; Akiyama G; Matsuzaki S; Sato M; Moribe S; Koshikawa N; Cools AR.
XXIVth Collegium Internationale Neuro-Psychopharmacologicum (CINP) congress in Paris, Jun. 2004, Not invited

Comparative study of D1-like dopamine receptor agonists acting via different transduction mechanisms in relation to orofacial movements on mice
Tomiyama K; Makihara Y; Inoue M; Oka J; Waddington JL; Koshikawa N.
XXIVth Collegium Internationale Neuro-Psychopharmacologicum (CINP) congress in Paris, Jun. 2004, Not invited

GABA_A receptors in the pedunculopontine tegmental nucleus play a crucial role in rat shell-specific dopamine-mediated turning behavior
Ikeda H; Akiyama G; Matsuzaki S; Sato M; Moribe S; Koshikawa N.
1st International Symposium of Neurobehavioral Pharmacology, Sep. 2003, Not invited

Contribution of vesicular and cytosolic dopamine to dexamphetamine- and SKF38393-induced striatal dopamine efflux in rats in vivo
Saigusa; T.; Fusa; K.; Takada; K.; Tomiyama; K.; Koshikawa; N.; Cools A.R.
1st International Symposium of Neurobehavioral Pharmacology, Sep. 2003, Not invited

Resolution of D_1A, D₂ and D₃ receptor involvement in distinct topographies of orofacial dyskinesia using congenic mutants
Waddington; J.L.; Tomiyama; K.; McNamara; F.N.; Clifford; J.J.; Tighe; O.; Kinsella A.; Drago; J.; Fuchs; S.; Grandy D.K.; Low; M.L.; Rubinstein M.; Croke D.T. and Koshikawa; N.
Dopamine 2002, Jul. 2002, Not invited

Role of GABA_A receptors in the ventral pallidum and the pedunculopontine tegmental area in rat turning behaviour
Ikeda; H.; Akiyama; G.; Matsuzaki; S. and Koshikawa; N.
Collegium Internationale Neuro-Psychopharmacologium (CINP) Regional Meeting Hiroshima, Oct. 2001, Not invited

Effects of SK&F 83959, a putative non-cyclase-coupled dopamine D1-like receptor agent, on rat repetitive jaw movements
Koshikawa; N.
7th World Congress of Biological Psychiatry, Jul. 2001, Not invited

Systemic comparison of behavioural phenotype in congenic mice with D1A, D2 or D3 dopamine receptor knockout: ethological and orofacial movement profiles
Waddington J.L.; McNamara; F.; Clifford; J.; Tomiyama; K.; Koshikawa; N. and Croke; D.T.
International Congress on Schizophrenia Research, Apr. 2001, Not invited

Assessment and pharmacological characterization of orofacial movements in mice : D₁-like vs D₂-like dopamine receptor regulation
Tomiyama; K.; McNamara; F.; Clifford; J.; Kinsella; A.; Koshikawa; N. and Waddington J.L.
The 9th International Cathecholamine Synposium, Apr. 2001, Not invited

Role of dopamine receptor subtypes in orofacial movements: analysis using D_1A, D₂, D₃ knockout mice
Tomiyama; K.; Clifford; J.; McNamara; F.; Kinsella; A.; Rubinstein; M.; Grandy; D.; Low; M.; Accili; D.; Fuchs; S.; Drago; J.; Croke; D.; Koshikawa; N. and Waddington J.L.
The 9th International Cathecholamine Symposium, Apr. 2001, Not invited

Role of dopamine receptor subtypes in orofacial movements: analysis using congenic D_1A, D₂ and D₃ ‘knockout’ mice
Tomiyama; K.; Clifford; J.; McNamara; F.; Drago; J.; Fuchs; S.; Grandy; D.; Low; M.; Rubinstein; M.; Kinsella; A.; Croke; D.; Koshikawa; N. and Waddington; J.
The 39th Annual Meeting of American College of Neuropsychopharmacology, Dec. 2000, Not invited

Pharmacological characterisation in mice of orofacial movements to D₁-like dopamine receptor function.
Tomiyama; K.; Koshikawa; N. and Waddington; J.L.
The 11th Annual Meeting of Irish Association of Pharmacologists, Nov. 2000, Not invited

Role of dopamine receptor subtypes in orofacial movements : analysis using congenic D_1A, D₂ and D₃ knockout mice
Tomiyama; K.; Clifford; J.; McNamara; F.; Kinsella; A.; Rubinstein; M.; Grandy; D.; Low; M.; Accili; D.; Fuchs; S.; Drago; J.; Croke; D.; Koshikawa; N. and Waddington; J.
The 12th Meeting of Irish Association of Pharmacologists, Nov. 2000, Not invited

Role of dopamine D₂ vs D₃ receptor subtypes in spontaneous orofacial movements: analysis using D₂vsD₃ knockout mice
Tomiyama; K.; Clifford; J.; McNamara; F.; Kinsella; A.; Rubinstein; M.; Grandy; D.; Low; M.; Accili; D.; Fuchs; S.; Drago; J.; Croke; D.; Koshikawa; N. and Waddington; J.
British association for psychopharmacology, Summer Meeting 2000, Jul. 2000, Not invited

Role of the dopamine D₂ receptor in orofacial movements: analysis using D₂ knockout mice
Tomiyama; K.; Clifford; J.J.; Kinsella; A.J.; Croke; D.T.; Koshikawa; N. and Waddington; J.L.
Royal College of Surgeons in Ireland Annual Research Day, Apr. 2000, Not invited

High and low responders to novelty; difference in mesolimbic noradrenaline-dopamine interaction
Saigusa; T.; Tuinstra; T.; Koshikawa; N. and Cools; A.R.
29th Annual Meeting of the European Brain and Behaviour Society, Sep. 1997, Not invited

Dopamine D₃ agonist 7-OH-DPAT attenuates morphine-induced motivational effect
Maeda; J.; Suzuki; T.; Funada; M.; Misawa; M.; Tomiyama; K.; Koshikawa; N. and Kobayashi; M.
57th Annual Scientific Meeting of the College on Problems of Drug Dependence (CPDD), Jun. 1995, Not invited

Unilateral stimulation of dopaminergic and cholinergic receptors in the nucleus accumbens affects dopamine release in the ipsilateral ventrolateral striatum of freely moving rats
Koshikawa; N.; Saigusa; T. Yoshida; Y. Kobayashi; M. and Cools; A.R.
IBAGS 5th Triennial Meeting, May 1995, Not invited

Dissimilarities between cholinergic and dopaminergic turning behaviour elicited from the nucleus accumbens of rats
Koshikawa; N.; Saigusa; T.; Kobayashi; M.
International Academy for Biomedical and Drug Research, Nov. 1994, Not invited

Role of dopamine receptors in turning behaviour induced by unilateral injections of carbachol into the nucleus accumbens of intact rats
Koshikawa; N.; Saigusa; T.; Kobayashi; M.
5th International Meeting of the European Behavioural Pharmacology Society, Sep. 1994, Not invited

Effects of acute and chronic treatments with tianeptine and paroxetine on 5-HTP-evoked changes in 5-HT content of rat hippocampal dialysates
Koshikawa; N.; Tomiyama; K. and Stephenson; J.D.
Winter Meeting of the British Pharmacological Society, Jan. 1994, Not invited

Involvement of striatal GABAergic mechanisms in apomorphine- and pilocarpine-induced jaw movements in rats
Kikuchi de Beltran; K.; Koshikawa; N.; Saigusa; T.; Kobayashi; M.
XVIIIth Collegium Internationale Neuro-psychopharmacologicum (C.I.N.P.) Congress, Jul. 1992, Not invited

Turning behaviour elicited by dopamine D₁ and D₂ receptor agonists; role of the nucleus accumbens
Koshikawa; N.; Saigusa; T.; Kitamura; M.; Kobayashi; M.
7th International Catecholamine Symposium, Jun. 1992, Not invited

Striatal ACh/DA interaction in the control of repetitive oral movements of rats
Kikuchi de Beltran; K.; Koshikawa; N. and Kobayashi; M.
The 10th Japan-Korea Joint Seminar on Pharmacology, Nov. 1991, Not invited

Effects of intrastriatal injections of cholinergic drugs on apomorphine-induced jaw movements in rats
Kikuchi de Beltran; K.; Tomiyama; K.; Koshikawa; N.; Kobayashi; M.
XVIIth Collegium Internationale Neuro-psychopharmacologicum (C.I.N.P.) Congress, Sep. 1990, Not invited

Behavioural effects of tianeptine in rats are consistent with increased 5-HT uptake
Stephenson; J.D.; Mocar; E.; Koshikawa; N.
XVIIth Collegium Internationale Neuro-psychopharmacologicum (C.I.N.P.) Congress, Sep. 1990, Not invited

Facilitatory effects of CCK-8 in the dorsomedial nucleus accumbens on apomorphine-induced jaw movements in rats, Eur. J. Pharmacol. Suppl., 1118, 1990,
Koshikawa; N.; Kikuchi de Beltran; K.; Kobayashi; M.; Stephenson; J.D.
XIth International Congress of Pharmacology (IUPHR), Jul. 1990, Not invited

Brain β-adrenoceptor loss after a phenerzine injection does not involve receptor internalization
Koshikawa; N.; Maruyama; Y.; Kobayashi; M. and Campbell; I. C.
Leeds Meeting of the British Pharmacological Sciety, Jul. 1989, Not invited

Injection of sulpiride into the dorsal and ventral striatum of rats have different effects on apomorphine-induced jaw movements
Koshikawa; N.; Aoki; S.; Hiruta; M.; Kobayashi; M.; Stephenson; J.D.
XVIth Collegium Internationale Neuro-psychopharmacologicum (C.I.N.P.) Congress, Aug. 1988, Not invited

Tolerance to the potentiating effects of spinal 5-HT₂ receptor activation on a flexor reflex in spinal rats
Stephenson; J.D. and Koshikawa; N.
Winter Meeting of the British Pharmacological Society, Dec. 1986, Not invited

Adrenergic systems, antidepressant drugs and depression
Campbell; I.C.; Kobayashi; M.; Koshikawa; N.
Satelight Symposium of 16th Annual Meeting of The Japanese Society of Neuropsychopharmacology, Sep. 1986, Not invited

β-Adrenoceptor desensitisation by antidepressant drugs does not involve receptor internalization
Campbell; I.C.; Koshikawa; N.
16th Annual Meeting of The Japanese Society of Neuropsychopharmacology, Sep. 1986, Not invited

Association between down-regulation of cortical 5-HT₂ receptors and waning of a related behavioural response
Koshikawa; N.; Smokcum; R.W.J.; Stephenson; J.D.
Winter Meeting of the British Pharmacological Society, Dec. 1984, Not invited

The effects of sulpiride injection into the caudate-putamen and nucleus accumbens on methamphetamine-induced hyperlocomotion and strereotyped gnawing activity
Kobayashi; M.; Koshikawa; N.
9th International Congress of Pharmacology (IUPHAR), Jul. 1984, Not invited

Effects of d-amphetamine on the 5-HT metabolism in rat brain
Koshikawa; N.; Kobayashi; M
8th International Congress of Pharmacology (IUPHAR), Jul. 1981, Not invited

Jan. 2009 - Present
Collegium Internationale Neuro-Psychopharmacologium

Jan. 1995 - Present
International Basal Ganglia Society

Jan. 1994 - Present
European Behavioural Pharmacology Society

Sep. 1984 - Present
日本神経精神薬理学会

Feb. 1976 - Present
日本薬理学会

Jun. 1975 - Present
歯科基礎医学会

Feb. 1997 - Apr. 2016
日本歯科薬物療法学会

Jul. 1986 - Mar. 2016
日本歯科心身医学会

Feb. 1976 - Mar. 2016
日本神経化学会

Feb. 1976 - Mar. 2016
日本薬学会